David Gaieski

TitleAssoc Professor
InstitutionThomas Jefferson University
DepartmentEmergency Medicine
Address1020 Sansom St.
Philadelphia PA 19107
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Perman SM, Mikkelsen ME, Goyal M, Ginde A, Bhardwaj A, Drumheller B, Sante SC, Agarwal AK, Gaieski DF. The sensitivity of qSOFA calculated at triage and during emergency department treatment to rapidly identify sepsis patients. Sci Rep. 2020 11 23; 10(1):20395. PMID: 33230117.
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    2. Mohr NM, Zebrowski AM, Gaieski DF, Buckler DG, Carr BG. Inpatient hospital performance is associated with post-discharge sepsis mortality. Crit Care. 2020 10 27; 24(1):626. PMID: 33109211.
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    3. Nguyen ML, Gause E, Mills B, Tonna JE, Alvey H, Saczkowski R, Grunau B, Becker LB, Gaieski DF, Youngquist S, Gunnerson K, England P, Hamilton J, Badulak J, Mandell SP, Bulger EM, Johnson NJ. Traumatic and hemorrhagic complications after extracorporeal cardiopulmonary resuscitation for out-of-hospital cardiac arrest. Resuscitation. 2020 Dec; 157:225-229. PMID: 33058992.
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    4. Sardesai I, Grover J, Garg M, Nanayakkara PWB, Di Somma S, Paladino L, Anderson HL, Gaieski D, Galwankar SC, Stawicki SP. Short Term Home Oxygen Therapy for COVID-19 patients: The COVID-HOT algorithm. J Family Med Prim Care. 2020 Jul; 9(7):3209-3219. PMID: 33102272.
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    5. Gaieski DF. Targeted Temperature Management for Cardiac Arrest. N Engl J Med. 2020 Jun 25; 382(26):e109. PMID: 32579840.
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    6. Galwankar SC, Paladino L, Gaieski DF, Nanayakkara KDPWB, Somma SD, Grover J, Stawicki SP. Management Algorithm for Subclinical Hypoxemia in Coronavirus Disease-2019 Patients: Intercepting the "Silent Killer". J Emerg Trauma Shock. 2020 Apr-Jun; 13(2):110-113. PMID: 33013088.
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    7. Sinha S, Sardesai I, Galwankar SC, Nanayakkara PWB, Narasimhan DR, Grover J, Anderson HL, Paladino L, Gaieski DF, Somma SD, Stawicki SP. Optimizing respiratory care in coronavirus disease-2019: A comprehensive, protocolized, evidence-based, algorithmic approach. Int J Crit Illn Inj Sci. 2020 Apr-Jun; 10(2):56-63. PMID: 32904508.
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    8. Stawicki SP, Jeanmonod R, Miller AC, Paladino L, Gaieski DF, Yaffee AQ, De Wulf A, Grover J, Papadimos TJ, Bloem C, Galwankar SC, Chauhan V, Firstenberg MS, Di Somma S, Jeanmonod D, Garg SM, Tucci V, Anderson HL, Fatimah L, Worlton TJ, Dubhashi SP, Glaze KS, Sinha S, Opara IN, Yellapu V, Kelkar D, El-Menyar A, Krishnan V, Venkataramanaiah S, Leyfman Y, Saoud Al Thani HA, Wb Nanayakkara P, Nanda S, Cioè-Peña E, Sardesai I, Chandra S, Munasinghe A, Dutta V, Dal Ponte ST, Izurieta R, Asensio JA, Garg M. The 2019-2020 Novel Coronavirus (Severe Acute Respiratory Syndrome Coronavirus 2) Pandemic: A Joint American College of Academic International Medicine-World Academic Council of Emergency Medicine Multidisciplinary COVID-19 Working Group Consensus Paper. J Glob Infect Dis. 2020 Apr-Jun; 12(2):47-93. PMID: 32773996.
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    9. Lindsell CJ, McGlothlin A, Nwosu S, Rice TW, Hall A, Bernard GR, Busse LW, Ely EW, Fowler AA, Gaieski DF, Hinson JS, Hooper MH, Jackson JC, Kelen GD, Levine M, Martin GS, Rothman RE, Sevransky JE, Viele K, Wright DW, Hager DN. In response: Letter on update to the Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) protocol. Trials. 2020 Apr 22; 21(1):351. PMID: 32317004.
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    10. Lindsell CJ, McGlothlin A, Nwosu S, Rice TW, Hall A, Bernard GR, Busse LW, Ely EW, Fowler AA, Gaieski DF, Hinson JS, Hooper MH, Jackson JC, Kelen GD, Levine M, Martin GS, Rothman RE, Sevransky JE, Viele K, Wright DW, Hager DN. Update to the Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) protocol: statistical analysis plan for a prospective, multicenter, double-blind, adaptive sample size, randomized, placebo-controlled, clinical trial. Trials. 2019 Dec 04; 20(1):670. PMID: 31801567.
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    11. Hager DN, Hooper MH, Bernard GR, Busse LW, Ely EW, Fowler AA, Gaieski DF, Hall A, Hinson JS, Jackson JC, Kelen GD, Levine M, Lindsell CJ, Malone RE, McGlothlin A, Rothman RE, Viele K, Wright DW, Sevransky JE, Martin GS. The Vitamin C, Thiamine and Steroids in Sepsis (VICTAS) Protocol: a prospective, multi-center, double-blind, adaptive sample size, randomized, placebo-controlled, clinical trial. Trials. 2019 Apr 05; 20(1):197. PMID: 30953543.
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    12. Nakashima T, Noguchi T, Tahara Y, Nishimura K, Ogata S, Yasuda S, Onozuka D, Morimura N, Nagao K, Gaieski DF, Asai Y, Yokota H, Nara S, Hase M, Atsumi T, Sakamoto T. Patients With Refractory Out-of-Cardiac Arrest and Sustained Ventricular Fibrillation as Candidates for Extracorporeal Cardiopulmonary Resuscitation - Prospective Multi-Center Observational Study. Circ J. 2019 Mar 20. PMID: 30890669.
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    13. Abella BS, Gaieski DF. Coronary Angiography after Cardiac Arrest - The Right Timing or the Right Patients? N Engl J Med. 2019 Mar 18. PMID: 30883048.
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    14. Johnson NJ, Caldwell E, Carlbom DJ, Gaieski DF, Prekker ME, Rea TD, Sayre M, Hough CL. The acute respiratory distress syndrome after out-of-hospital cardiac arrest: Incidence, risk factors, and outcomes. Resuscitation. 2019 Jan 14; 135:37-44. PMID: 30654012.
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    15. Perman SM, Gaieski DF. Do the Current Findings for Hemodynamic Optimization of the Postcardiac Arrest Patient Take Us Out of Our Arterial Pressure Comfort Zone? Crit Care Med. 2019 Jan; 47(1):138-139. PMID: 30557249.
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    16. Coppler PJ, Abella BS, Callaway CW, Chae MK, Choi SP, Elmer J, Kim WY, Kim YM, Kurz M, Oh JS, Reynolds JC, Rittenberger JC, Sawyer KN, Youn CS, Lee BK, Gaieski DF. Variability of extracorporeal cardiopulmonary resuscitation utilization for refractory adult out-of-hospital cardiac arrest: an international survey study. Clin Exp Emerg Med. 2018 Jun; 5(2):100-106. PMID: 29706060.
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    17. Meyer N, Harhay MO, Small DS, Prescott HC, Bowles KH, Gaieski DF, Mikkelsen ME. Temporal Trends in Incidence, Sepsis-Related Mortality, and Hospital-Based Acute Care After Sepsis. Crit Care Med. 2018 Mar; 46(3):354-360. PMID: 29474320.
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    18. Shelton SK, Chukwulebe SB, Gaieski DF, Abella BS, Carr BG, Perman SM. Validation of an ICD code for accurately identifying emergency department patients who suffer an out-of-hospital cardiac arrest. Resuscitation. 2018 Jan 16; 125:8-11. PMID: 29341874.
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    19. Johnson NJ, Carlbom DJ, Gaieski DF. Ventilator Management and Respiratory Care After Cardiac Arrest: Oxygenation, Ventilation, Infection, and Injury. Chest. 2017 Nov 22. PMID: 29175085.
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    20. Yao Y, Johnson NJ, Perman SM, Ramjee V, Grossestreuer AV, Gaieski DF. Myocardial dysfunction after out-of-hospital cardiac arrest: predictors and prognostic implications. Intern Emerg Med. 2017 Oct 05. PMID: 28983759.
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    21. Gaieski DF, O'Brien NF, Hernandez R. Emergency Neurologic Life Support: Meningitis and Encephalitis. Neurocrit Care. 2017 Sep; 27(Suppl 1):124-133. PMID: 28916998.
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    22. Grossestreuer AV, Gaieski DF, Donnino MW, Nelson JIM, Mutter EL, Carr BG, Abella BS, Wiebe DJ. Cardiac arrest risk standardization using administrative data compared to registry data. PLoS One. 2017; 12(8):e0182864. PMID: 28783754.
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    23. Agarwal AK, Gaieski DF. Blood culture contamination and ED overcrowding. Is there a connection? Am J Emerg Med. 2018 Feb; 36(2):326-327. PMID: 28739391.
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    24. Agarwal AK, Gaieski DF. Response to letter regarding article, "The impact of emergency department crowding upon early interventions and mortality in patients with severe sepsis." Am J Emerg Med. 2017 Jul 12. PMID: 28784256.
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    25. Schuetz P, Birkhahn R, Sherwin R, Jones AE, Singer A, Kline JA, Runyon MS, Self WH, Courtney DM, Nowak RM, Gaieski DF, Ebmeyer S, Johannes S, Wiemer JC, Schwabe A, Shapiro NI. Serial Procalcitonin Predicts Mortality in Severe Sepsis Patients: Results From the Multicenter Procalcitonin MOnitoring SEpsis (MOSES) Study. Crit Care Med. 2017 May; 45(5):781-789. PMID: 28257335.
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    26. Chauhan V, Shah PK, Galwankar S, Sammon M, Hosad P, Erickson TB, Gaieski DF, Grover J, Hegde AV, Hoek TV, Jarwani B, Kataria H, LaBresh KA, Manjunath CN, Nagamani AC, Patel A, Patel K, Ramesh D, Rangaraj R, Shamanur N, Sridhar L, Srinivasa KH, Tyagi S. The 2017 International Joint Working Group recommendations of the Indian College of Cardiology, the Academic College of Emergency Experts, and INDUSEM on the management of low-risk chest pain in emergency departments across India. J Emerg Trauma Shock. 2017 Apr-Jun; 10(2):74-81. PMID: 28367012.
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    27. Dietz BW, Jones TK, Small DS, Gaieski DF, Mikkelsen ME. The Relationship Between Index Hospitalizations, Sepsis, and Death or Transition to Hospice Care During 30-Day Hospital Readmissions. Med Care. 2017 Apr; 55(4):362-370. PMID: 27820595.
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    28. Gaieski DF, Agarwal AK, Abella BS, Neumar RW, Mechem C, Cater SW, Shofer FS, Leary M, Pajerowski WP, Becker LB, Carr B, Merchant R, Band RA. Adult out-of-hospital cardiac arrest in philadelphia from 2008-2012: An epidemiological study. Resuscitation. 2017 Jun; 115:17-22. PMID: 28343957.
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    29. Tolins ML, Henning DJ, Gaieski DF, Grossestreuer AV, Jaworski A, Johnson NJ. Initial arterial carbon dioxide tension is associated with neurological outcome after resuscitation from cardiac arrest. Resuscitation. 2017 May; 114:53-58. PMID: 28268187.
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    30. Gaieski DF, Agarwal AK, Mikkelsen ME, Drumheller B, Cham Sante S, Shofer FS, Goyal M, Pines JM. The impact of ED crowding on early interventions and mortality in patients with severe sepsis. Am J Emerg Med. 2017 Jul; 35(7):953-960. PMID: 28233644.
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    31. Donnino MW, Liu X, Andersen LW, Rittenberger JC, Abella BS, Gaieski DF, Ornato JP, Gazmuri RJ, Grossestreuer AV, Cocchi MN, Abbate A, Uber A, Clore J, Peberdy MA, Callaway CW. Characterization of mitochondrial injury after cardiac arrest (COMICA). Resuscitation. 2017 Apr; 113:56-62. PMID: 28126408.
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    32. Wilson M, Grossestreuer AV, Gaieski DF, Abella BS, Frohna W, Goyal M. Incidence of coronary intervention in cardiac arrest survivors with non-shockable initial rhythms and no evidence of ST-elevation MI (STEMI). Resuscitation. 2016 Nov 23. PMID: 27888672.
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    33. Grossestreuer AV, Gaieski DF, Abella BS, Wiebe DJ, Moskowitz A, Ikeda DJ, Haukoos JS, Perman SM. Factors associated with post-arrest withdrawal of life-sustaining therapy. Resuscitation. 2017 Jan; 110:114-119. PMID: 27840307.
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    34. Grossestreuer AV, Gaieski DF, Donnino MW, Wiebe DJ, Abella BS. Magnitude of temperature elevation is associated with neurologic and survival outcomes in resuscitated cardiac arrest patients with postrewarming pyrexia. J Crit Care. 2016 Nov 9; 38:78-83. PMID: 27866109.
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    35. Grossestreuer AV, Abella BS, Sheak KR, Cinousis MJ, Perman SM, Leary M, Wiebe DJ, Gaieski DF. Inter-rater reliability of post-arrest cerebral performance category (CPC) scores. Resuscitation. 2016 Dec; 109:21-24. PMID: 27650863.
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    36. Tonna JE, Johnson NJ, Greenwood J, Gaieski DF, Shinar Z, Bellezo JM, Becker L, Shah AP, Youngquist ST, Mallin MP, Fair JF, Gunnerson KJ, Weng C, McKellar S. Practice characteristics of Emergency Department extracorporeal cardiopulmonary resuscitation (eCPR) programs in the United States: The current state of the art of Emergency Department extracorporeal membrane oxygenation (ED ECMO). Resuscitation. 2016 Oct; 107:38-46. PMID: 27523953.
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    37. Johnson NJ, Rosselot B, Perman SM, Dodampahala K, Goyal M, Gaieski DF, Grossestreuer AV. The association between hemoglobin concentration and neurologic outcome after cardiac arrest. J Crit Care. 2016 Dec; 36:218-222. PMID: 27546775.
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    38. Coppler PJ, Sawyer KN, Youn CS, Choi SP, Park KN, Kim YM, Reynolds JC, Gaieski DF, Lee BK, Oh JS, Kim WY, Moon HJ, Abella BS, Elmer J, Callaway CW, Rittenberger JC. Variability of Post-Cardiac Arrest Care Practices Among Cardiac Arrest Centers: United States and South Korean Dual Network Survey of Emergency Physician Research Principal Investigators. Ther Hypothermia Temp Manag. 2017 Mar; 7(1):30-35. PMID: 27419613.
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    39. Johnson NJ, Dodampahala K, Rosselot B, Perman SM, Mikkelsen ME, Goyal M, Gaieski DF, Grossestreuer AV. The Association Between Arterial Oxygen Tension and Neurological Outcome After Cardiac Arrest. Ther Hypothermia Temp Manag. 2017 Mar; 7(1):36-41. PMID: 27383062.
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    40. Perman SM, Grossestreuer AV, Wiebe DJ, Carr BG, Abella BS, Gaieski DF. Response to Letter Regarding Article, "The Utility of Therapeutic Hypothermia for Post-Cardiac Arrest Syndrome Patients With an Initial Nonshockable Rhythm". Circulation. 2016 Apr 26; 133(17):e612. PMID: 27143159; PMCID: PMC5035132.
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    41. Agarwal AK, Gaieski DF, Perman SM, Leary M, Delfin G, Abella BS, Carr BG. Telemedicine REsuscitation and Arrest Trial (TREAT): A feasibility study of real-time provider-to-provider telemedicine for the care of critically ill patients. Heliyon. 2016 Apr; 2(4):e00099. PMID: 27441272.
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    42. Sun A, Netzer G, Small DS, Hanish A, Fuchs BD, Gaieski DF, Mikkelsen ME. Association Between Index Hospitalization and Hospital Readmission in Sepsis Survivors. Crit Care Med. 2016 Mar; 44(3):478-87. PMID: 26571185.
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    43. Nagao K, Nonogi H, Yonemoto N, Gaieski DF, Ito N, Takayama M, Shirai S, Furuya S, Tani S, Kimura T, Saku K. Duration of Prehospital Resuscitation Efforts After Out-of-Hospital Cardiac Arrest. Circulation. 2016 Apr 5; 133(14):1386-96. PMID: 26920493.
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    44. Peberdy MA, Andersen LW, Abbate A, Thacker LR, Gaieski D, Abella BS, Grossestreuer AV, Rittenberger JC, Clore J, Ornato J, Cocchi MN, Callaway C, Donnino M. Inflammatory markers following resuscitation from out-of-hospital cardiac arrest-A prospective multicenter observational study. Resuscitation. 2016 Jun; 103:117-24. PMID: 26826561.
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    45. Gaieski DF, Nathan BR, O'Brien NF. Emergency Neurologic Life Support: Meningitis and Encephalitis. Neurocrit Care. 2015 Dec; 23 Suppl 2:S110-8. PMID: 26438456.
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    46. Perman SM, Grossestreuer AV, Wiebe DJ, Carr BG, Abella BS, Gaieski DF. The Utility of Therapeutic Hypothermia for Post-Cardiac Arrest Syndrome Patients With an Initial Nonshockable Rhythm. Circulation. 2015 Dec 01; 132(22):2146-51. PMID: 26572795; PMCID: PMC4881859.
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    47. Drumheller BC, Agarwal A, Mikkelsen ME, Sante SC, Weber AL, Goyal M, Gaieski DF. Risk factors for mortality despite early protocolized resuscitation for severe sepsis and septic shock in the emergency department. J Crit Care. 2016 Feb; 31(1):13-20. PMID: 26611382.
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    48. Ramjee V, Grossestreuer AV, Yao Y, Perman SM, Leary M, Kirkpatrick JN, Forfia PR, Kolansky DM, Abella BS, Gaieski DF. Right ventricular dysfunction after resuscitation predicts poor outcomes in cardiac arrest patients independent of left ventricular function. Resuscitation. 2015 Nov; 96:186-91. PMID: 26318576.
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    49. Katz AZ, Grossestreuer AV, Gaieski DF, Abella BS, Kumar V, Perrone J. Outcomes of patients resuscitated from cardiac arrest in the setting of drug overdose. Resuscitation. 2015 Sep; 94:23-7. PMID: 26126505.
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    50. Jones TK, Fuchs BD, Small DS, Halpern SD, Hanish A, Umscheid CA, Baillie CA, Kerlin MP, Gaieski DF, Mikkelsen ME. Post-Acute Care Use and Hospital Readmission after Sepsis. Ann Am Thorac Soc. 2015 Jun; 12(6):904-13. PMID: 25751120.
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    51. Ortego A, Gaieski DF, Fuchs BD, Jones T, Halpern SD, Small DS, Sante SC, Drumheller B, Christie JD, Mikkelsen ME. Hospital-based acute care use in survivors of septic shock. Crit Care Med. 2015 Apr; 43(4):729-37. PMID: 25365724.
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    52. Gaulton TG, Marshall MacNabb C, Mikkelsen ME, Agarwal AK, Cham Sante S, Shah CV, Gaieski DF. A retrospective cohort study examining the association between body mass index and mortality in severe sepsis. Intern Emerg Med. 2015 Jun; 10(4):471-9. PMID: 25647585.
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    53. Johnson N, Hsu C, Gaieski DF. Reply to Letter: "Extracoporeal life support treatment bundle for refractory cardiac arrest". Resuscitation. 2015 Feb; 87:e7. PMID: 25500747.
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    54. Gaieski D, Sakamoto T, Greer D, Gaieski D. Perspectives on temperature management. Ther Hypothermia Temp Manag. 2014 Dec; 4(4):150-3. PMID: 25490282.
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    55. Hsu CH, Li J, Cinousis MJ, Sheak KR, Gaieski DF, Abella BS, Leary M. Cerebral performance category at hospital discharge predicts long-term survival of cardiac arrest survivors receiving targeted temperature management*. Crit Care Med. 2014 Dec; 42(12):2575-81. PMID: 25072759.
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    56. Mazer-Amirshahi M, Perman SM, Grossestreuer AV, Neumar RW, Gaieski DF. Magnesium depletion in patients treated with therapeutic hypothermia after cardiac arrest. Ther Hypothermia Temp Manag. 2014 Dec; 4(4):188-92. PMID: 25247997.
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    57. Scott HF, Donoghue AJ, Gaieski DF, Marchese RF, Mistry RD. Effectiveness of physical exam signs for early detection of critical illness in pediatric systemic inflammatory response syndrome. BMC Emerg Med. 2014; 14:24. PMID: 25407007.
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    58. Balamuth F, Weiss SL, Neuman MI, Scott H, Brady PW, Paul R, Farris RW, McClead R, Hayes K, Gaieski D, Hall M, Shah SS, Alpern ER. Pediatric severe sepsis in U.S. children's hospitals. Pediatr Crit Care Med. 2014 Nov; 15(9):798-805. PMID: 25162514.
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    59. Perman SM, Ellenberg JH, Grossestreuer AV, Gaieski DF, Leary M, Abella BS, Carr BG. Shorter time to target temperature is associated with poor neurologic outcome in post-arrest patients treated with targeted temperature management. Resuscitation. 2015 Mar; 88:114-9. PMID: 25447429.
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    60. Ranola PA, Merchant RM, Perman SM, Khan AM, Gaieski D, Caplan AL, Kirkpatrick JN. How long is long enough, and have we done everything we should?--Ethics of calling codes. J Med Ethics. 2015 Aug; 41(8):663-6. PMID: 25249374.
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    61. Gaieski DF, Edwards JM, Kallan MJ, Mikkelsen ME, Goyal M, Carr BG. The relationship between hospital volume and mortality in severe sepsis. Am J Respir Crit Care Med. 2014 Sep 15; 190(6):665-74. PMID: 25117723.
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    62. Johnson NJ, Acker M, Hsu CH, Desai N, Vallabhajosyula P, Lazar S, Horak J, Wald J, McCarthy F, Rame E, Gray K, Perman SM, Becker L, Cowie D, Grossestreuer A, Smith T, Gaieski DF. Extracorporeal life support as rescue strategy for out-of-hospital and emergency department cardiac arrest. Resuscitation. 2014 Nov; 85(11):1527-32. PMID: 25201611.
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    63. Ginde AA, Blatchford PJ, Trzeciak S, Hollander JE, Birkhahn R, Otero R, Osborn TM, Moretti E, Nguyen HB, Gunnerson KJ, Milzman D, Gaieski DF, Goyal M, Cairns CB, Rivers EP, Shapiro NI. Age-related differences in biomarkers of acute inflammation during hospitalization for sepsis. Shock. 2014 Aug; 42(2):99-107. PMID: 24978893.
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    64. Donnino MW, Andersen LW, Giberson T, Gaieski DF, Abella BS, Peberdy MA, Rittenberger JC, Callaway CW, Ornato J, Clore J, Grossestreuer A, Salciccioli J, Cocchi MN. Initial lactate and lactate change in post-cardiac arrest: a multicenter validation study. Crit Care Med. 2014 Aug; 42(8):1804-11. PMID: 24776606.
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    65. Whittaker SA, Fuchs BD, Gaieski DF, Christie JD, Goyal M, Meyer NJ, Kean C, Small DS, Bellamy SL, Mikkelsen ME. Epidemiology and outcomes in patients with severe sepsis admitted to the hospital wards. J Crit Care. 2015 Feb; 30(1):78-84. PMID: 25128441.
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    66. Mikkelsen ME, Gaieski DF. The authors reply. Crit Care Med. 2014 Jul; 42(7):e546-7. PMID: 24933078.
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    67. Perman SM, Gaieski DF. Neurologic status on presentation to a Heart Attack Centre: a predictor of recovery or more aptly, a predictor of injury? Resuscitation. 2014 Jul; 85(7):851-2. PMID: 24930019.
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    68. Gaieski DF, Goyal M, Perman SM. "Are you sure she will not recover?" Multimodal prognostication provides increased certainty about poor outcomes prediction. Crit Care Med. 2014 Jun; 42(6):1535-6. PMID: 24836784.
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    69. Perman SM, Goyal M, Neumar RW, Topjian AA, Gaieski DF. Clinical applications of targeted temperature management. Chest. 2014 Feb; 145(2):386-93. PMID: 24493510.
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    70. Gaieski DF, Beylin ME, Abella BS, Grossestreuer AV, Perman SM. What is the optimal post-arrest hemodynamic strategy? Towards personalized resuscitation strategies. Intensive Care Med. 2014 Mar; 40(3):466. PMID: 24420500.
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    71. Grossestreuer AV, Perman SM, Gaieski DF. Reply to Letter: Uneventful neurological outcome in case of late awakening after cardiac arrest treated with hypothermia. Resuscitation. 2014 Mar; 85(3):e41-2. PMID: 24412760.
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    72. Salhi RA, Edwards JM, Gaieski DF, Band RA, Abella BS, Carr BG. Access to care for patients with time-sensitive conditions in Pennsylvania. Ann Emerg Med. 2014 May; 63(5):572-9. PMID: 24368055.
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    73. Gugelmann HM, Gaieski DF. Beau's Lines After Cardiac Arrest. Ther Hypothermia Temp Manag. 2013 Dec; 3(4):199-202. PMID: 24834950.
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    74. Leary M, Cinousis MJ, Mikkelsen ME, Gaieski DF, Abella BS, Fuchs BD. The association of body mass index with time to target temperature and outcomes following post-arrest targeted temperature management. Resuscitation. 2014 Feb; 85(2):244-7. PMID: 24231571.
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    75. Mikkelsen ME, Shah CV, Meyer NJ, Gaieski DF, Lyon S, Miltiades AN, Goyal M, Fuchs BD, Bellamy SL, Christie JD. The epidemiology of acute respiratory distress syndrome in patients presenting to the emergency department with severe sepsis. Shock. 2013 Nov; 40(5):375-81. PMID: 23903852.
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    76. Mikkelsen ME, Gaieski DF. Classifying infections in the ICU: seeking certainty in an uncertain environment. Crit Care Med. 2013 Oct; 41(10):2452-3. PMID: 24060781.
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    77. Gaulton TG, Weiner MG, Morales KH, Gaieski DF, Mehta J, Lautenbach E. The effect of obesity on clinical outcomes in presumed sepsis: a retrospective cohort study. Intern Emerg Med. 2014 Mar; 9(2):213-21. PMID: 24072354.
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    78. Gaieski DF, Goyal M. What is sepsis? What is severe sepsis? What is septic shock? Searching for objective definitions among the winds of doctrines and wild theories. Expert Rev Anti Infect Ther. 2013 Sep; 11(9):867-71. PMID: 24004328.
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    79. Beylin ME, Perman SM, Abella BS, Leary M, Shofer FS, Grossestreuer AV, Gaieski DF. Higher mean arterial pressure with or without vasoactive agents is associated with increased survival and better neurological outcomes in comatose survivors of cardiac arrest. Intensive Care Med. 2013 Nov; 39(11):1981-8. PMID: 23995983.
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    80. Grossestreuer AV, Abella BS, Leary M, Perman SM, Fuchs BD, Kolansky DM, Beylin ME, Gaieski DF. Time to awakening and neurologic outcome in therapeutic hypothermia-treated cardiac arrest patients. Resuscitation. 2013 Dec; 84(12):1741-6. PMID: 23916554.
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    81. Salciccioli JD, Cocchi MN, Rittenberger JC, Peberdy MA, Ornato JP, Abella BS, Gaieski DF, Clore J, Gautam S, Giberson T, Callaway CW, Donnino MW. Continuous neuromuscular blockade is associated with decreased mortality in post-cardiac arrest patients. Resuscitation. 2013 Dec; 84(12):1728-33. PMID: 23796602.
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    82. Mikkelsen ME, Christie JD, Abella BS, Kerlin MP, Fuchs BD, Schweickert WD, Berg RA, Mosesso VN, Shofer FS, Gaieski DF. Use of therapeutic hypothermia after in-hospital cardiac arrest. Crit Care Med. 2013 Jun; 41(6):1385-95. PMID: 23518870.
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    83. Gaieski DF, Edwards JM, Kallan MJ, Carr BG. Benchmarking the incidence and mortality of severe sepsis in the United States. Crit Care Med. 2013 May; 41(5):1167-74. PMID: 23442987.
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    84. Gaieski DF, Grossestreuer AV, Abella BS. Reply to letter: association of serum lactate and survival outcomes after cardiac arrest. Resuscitation. 2013 Aug; 84(8):e90-1. PMID: 23643783.
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    85. Whittaker SA, Mikkelsen ME, Gaieski DF, Koshy S, Kean C, Fuchs BD. Severe sepsis cohorts derived from claims-based strategies appear to be biased toward a more severely ill patient population. Crit Care Med. 2013 Apr; 41(4):945-53. PMID: 23385099.
      Citations:    
    86. Wallace SK, Abella BS, Shofer FS, Leary M, Agarwal AK, Mechem CC, Gaieski DF, Becker LB, Neumar RW, Band RA. Effect of time of day on prehospital care and outcomes after out-of-hospital cardiac arrest. Circulation. 2013 Apr 16; 127(15):1591-6. PMID: 23509060.
      Citations:    
    87. Johnson NJ, Gaieski DF, Allen SR, Perrone J, DeRoos F. A review of emergency cardiopulmonary bypass for severe poisoning by cardiotoxic drugs. J Med Toxicol. 2013 Mar; 9(1):54-60. PMID: 23238774.
      Citations:    
    88. Starodub R, Abella BS, Grossestreuer AV, Shofer FS, Perman SM, Leary M, Gaieski DF. Association of serum lactate and survival outcomes in patients undergoing therapeutic hypothermia after cardiac arrest. Resuscitation. 2013 Aug; 84(8):1078-82. PMID: 23402966.
      Citations:    
    89. Gaieski DF, Drumheller BC, Goyal M, Fuchs BD, Shofer FS, Zogby K. Accuracy of Handheld Point-of-Care Fingertip Lactate Measurement in the Emergency Department. West J Emerg Med. 2013 Feb; 14(1):58-62. PMID: 23451290.
      Citations:    
    90. Blewer AL, Delfin G, Leary M, Gaieski DF, Abella BS. A structured educational intervention to improve targeted temperature management utilization after cardiac arrest. J Crit Care. 2013 Jun; 28(3):259-64. PMID: 23265288.
      Citations:    
    91. Leary M, Grossestreuer AV, Iannacone S, Gonzalez M, Shofer FS, Povey C, Wendell G, Archer SE, Gaieski DF, Abella BS. Pyrexia and neurologic outcomes after therapeutic hypothermia for cardiac arrest. Resuscitation. 2013 Aug; 84(8):1056-61. PMID: 23153649.
      Citations:    
    92. Scott HF, Donoghue AJ, Gaieski DF, Marchese RF, Mistry RD. The utility of early lactate testing in undifferentiated pediatric systemic inflammatory response syndrome. Acad Emerg Med. 2012 Nov; 19(11):1276-80. PMID: 23167859.
      Citations:    
    93. Johnson NJ, Salhi RA, Abella BS, Neumar RW, Gaieski DF, Carr BG. Emergency department factors associated with survival after sudden cardiac arrest. Resuscitation. 2013 Mar; 84(3):292-7. PMID: 23103887.
      Citations:    
    94. Gaieski DF, Nathan BR, Weingart SD, Smith WS. Emergency neurologic life support: meningitis and encephalitis. Neurocrit Care. 2012 Sep; 17 Suppl 1:S66-72. PMID: 22961702.
      Citations:    
    95. Goyal M, Houseman D, Johnson NJ, Christie J, Mikkelsen ME, Gaieski DF. Prevalence of acute lung injury among medical patients in the emergency department. Acad Emerg Med. 2012 Sep; 19(9):E1011-8. PMID: 22978727.
      Citations:    
    96. McCoy JV, Gaieski DF. What hemodynamic and perfusion variables are we monitoring in post-cardiac arrest patients…and why?. Crit Care Med. 2012 Aug; 40(8):2495-7. PMID: 22809955.
      Citations:    
    97. Gaieski DF, Goldman JD, Holtzman DL, Shoff WH, Shepherd SM, Mehta N, Goyal M. Algid malaria treated with early goal-directed therapy. Am J Emerg Med. 2013 Jan; 31(1):263.e5-10. PMID: 22795409.
      Citations:    
    98. Gonzalez MR, Esposito EC, Leary M, Gaieski DF, Kolansky DM, Chang G, Becker LB, Carr BG, Grossestreuer AV, Abella BS. Initial clinical predictors of significant coronary lesions after resuscitation from cardiac arrest. Ther Hypothermia Temp Manag. 2012 Jun; 2(2):73-7. PMID: 24717160.
      Citations:    
    99. Perman SM, Goyal M, Gaieski DF. Initial emergency department diagnosis and management of adult patients with severe sepsis and septic shock. Scand J Trauma Resusc Emerg Med. 2012; 20:41. PMID: 22737991.
      Citations:    
    100. Gaieski DF, Abella BS, Goyal M. CPR and postarrest care: overview, documentation, and databases. Chest. 2012 Apr; 141(4):1082-9. PMID: 22474150.
      Citations:    
    101. Perman SM, Kirkpatrick JN, Reitsma AM, Gaieski DF, Lau B, Smith TM, Leary M, Fuchs BD, Levine JM, Abella BS, Becker LB, Merchant RM. Timing of neuroprognostication in postcardiac arrest therapeutic hypothermia*. Crit Care Med. 2012 Mar; 40(3):719-24. PMID: 22080630.
      Citations:    
    102. Drumheller BC, McGrath M, Matsuura AC, Gaieski DF. Point-of-care urine albumin:creatinine ratio is associated with outcome in emergency department patients with sepsis: a pilot study. Acad Emerg Med. 2012 Mar; 19(3):259-64. PMID: 22435857.
      Citations:    
    103. Mani R, Schmitt SE, Mazer M, Putt ME, Gaieski DF. The frequency and timing of epileptiform activity on continuous electroencephalogram in comatose post-cardiac arrest syndrome patients treated with therapeutic hypothermia. Resuscitation. 2012 Jul; 83(7):840-7. PMID: 22366352.
      Citations:    
    104. Gaieski DF, Boller M, Becker LB. Emergency cardiopulmonary bypass: a promising rescue strategy for refractory cardiac arrest. Crit Care Clin. 2012 Apr; 28(2):211-29. PMID: 22433484.
      Citations:    
    105. Gaieski DF, Neumar RW, Fuchs B, Abella BS, Kolansky D, Delfin G, Leary M, Goyal M. Haemodynamic management strategies are not explicitly defined in the majority of therapeutic hypothermia implementation studies. Resuscitation. 2012 Jul; 83(7):835-9. PMID: 22212483.
      Citations:    
    106. Mikkelsen ME, Gaieski DF. Antibiotics in sepsis: Timing, appropriateness, and (of course) timely recognition of appropriateness. Crit Care Med. 2011 Sep; 39(9):2184-6. PMID: 21849829.
      Citations:    
    107. Band RA, Gaieski DF, Hylton JH, Shofer FS, Goyal M, Meisel ZF. Arriving by emergency medical services improves time to treatment endpoints for patients with severe sepsis or septic shock. Acad Emerg Med. 2011 Sep; 18(9):934-40. PMID: 21883637.
      Citations:    
    108. Gaieski JB, Owings AC, Vilar MG, Dulik MC, Gaieski DF, Gittelman RM, Lindo J, Gau L, Schurr TG. Genetic ancestry and indigenous heritage in a Native American descendant community in Bermuda. Am J Phys Anthropol. 2011 Nov; 146(3):392-405. PMID: 21994016.
      Citations:    
    109. Li J, Carr B, Goyal M, Gaieski DF. Sepsis: the inflammatory foundation of pathophysiology and therapy. Hosp Pract (1995). 2011 Aug; 39(3):99-112. PMID: 21881397.
      Citations:    
    110. Donnino MW, Rittenberger JC, Gaieski D, Cocchi MN, Giberson B, Peberdy MA, Abella BS, Bobrow BJ, Callaway C. The development and implementation of cardiac arrest centers. Resuscitation. 2011 Aug; 82(8):974-8. PMID: 21570761.
      Citations:    
    111. Perman SM, Chang AM, Hollander JE, Gaieski DF, Trzeciak S, Birkhahn R, Otero R, Osborn TM, Moretti E, Nguyen HB, Gunnerson KJ, Milzman D, Goyal M, Cairns CB, Ngo L, Rivers EP, Shapiro NI. Relationship between B-type natriuretic peptide and adverse outcome in patients with clinical evidence of sepsis presenting to the emergency department. Acad Emerg Med. 2011 Feb; 18(2):219-22. PMID: 21314784.
      Citations:    
    112. Band RA, Pryor JP, Gaieski DF, Dickinson ET, Cummings D, Carr BG. Injury-adjusted mortality of patients transported by police following penetrating trauma. Acad Emerg Med. 2011 Jan; 18(1):32-7. PMID: 21166730.
      Citations:    
    113. Rokos IC, Sanddal ND, Pancioli AM, Wolff C, Gaieski DF. Inter-hospital communications and transport: turning one-way funnels into two-way networks. Acad Emerg Med. 2010 Dec; 17(12):1279-85. PMID: 21122009.
      Citations:    
    114. Gaieski DF, Goyal M. History and current trends in sudden cardiac arrest and resuscitation in adults. Hosp Pract (1995). 2010 Nov; 38(4):44-53. PMID: 21068526.
      Citations:    
    115. Gaieski DF, Dickinson ET. Images in emergency medicine. Man with knee pain. Patellar tendon rupture. Ann Emerg Med. 2010 Oct; 56(4):333, 338. PMID: 20868904.
      Citations:    
    116. Leary M, Fried DA, Gaieski DF, Merchant RM, Fuchs BD, Kolansky DM, Edelson DP, Abella BS. Neurologic prognostication and bispectral index monitoring after resuscitation from cardiac arrest. Resuscitation. 2010 Sep; 81(9):1133-7. PMID: 20598422.
      Citations:    
    117. Lau B, Kirkpatrick JN, Merchant RM, Perman SM, Abella BS, Gaieski DF, Becker LB, Chiames C, Reitsma AM. Experiences of sudden cardiac arrest survivors regarding prognostication and advance care planning. Resuscitation. 2010 Aug; 81(8):982-6. PMID: 20435392.
      Citations:    
    118. Seymour CW, Band RA, Cooke CR, Mikkelsen ME, Hylton J, Rea TD, Goss CH, Gaieski DF. Out-of-hospital characteristics and care of patients with severe sepsis: a cohort study. J Crit Care. 2010 Dec; 25(4):553-62. PMID: 20381301.
      Citations:    
    119. Shapiro NI, Trzeciak S, Hollander JE, Birkhahn R, Otero R, Osborn TM, Moretti E, Nguyen HB, Gunnerson K, Milzman D, Gaieski DF, Goyal M, Cairns CB, Kupfer K, Lee SW, Rivers EP. The diagnostic accuracy of plasma neutrophil gelatinase-associated lipocalin in the prediction of acute kidney injury in emergency department patients with suspected sepsis. Ann Emerg Med. 2010 Jul; 56(1):52-59.e1. PMID: 20363526.
      Citations:    
    120. Gaieski DF, Mikkelsen ME, Band RA, Pines JM, Massone R, Furia FF, Shofer FS, Goyal M. Impact of time to antibiotics on survival in patients with severe sepsis or septic shock in whom early goal-directed therapy was initiated in the emergency department. Crit Care Med. 2010 Apr; 38(4):1045-53. PMID: 20048677.
      Citations:    
    121. Seymour CW, Cooke CR, Mikkelsen ME, Hylton J, Rea TD, Goss CH, Gaieski DF, Band RA. Out-of-hospital fluid in severe sepsis: effect on early resuscitation in the emergency department. Prehosp Emerg Care. 2010 Apr-Jun; 14(2):145-52. PMID: 20199228.
      Citations:    
    122. del Portal DA, Shofer F, Mikkelsen ME, Dorsey PJ, Gaieski DF, Goyal M, Synnestvedt M, Weiner MG, Pines JM. Emergency department lactate is associated with mortality in older adults admitted with and without infections. Acad Emerg Med. 2010 Mar; 17(3):260-8. PMID: 20370758.
      Citations:    
    123. Mikkelsen ME, Gaieski DF, Goyal M, Miltiades AN, Munson JC, Pines JM, Fuchs BD, Shah CV, Bellamy SL, Christie JD. Factors associated with nonadherence to early goal-directed therapy in the ED. Chest. 2010 Sep; 138(3):551-8. PMID: 20173053.
      Citations:    
    124. Gaieski DF, Fuchs B, Carr BG, Merchant R, Kolansky DM, Abella BS, Becker LB, Maguire C, Whitehawk M, Levine J, Goyal M. Practical implementation of therapeutic hypothermia after cardiac arrest. Hosp Pract (1995). 2009 Dec; 37(1):71-83. PMID: 20877174.
      Citations:    
    125. Pope JV, Jones AE, Gaieski DF, Arnold RC, Trzeciak S, Shapiro NI. Multicenter study of central venous oxygen saturation (ScvO(2)) as a predictor of mortality in patients with sepsis. Ann Emerg Med. 2010 Jan; 55(1):40-46.e1. PMID: 19854541.
      Citations:    
    126. Sagalyn E, Band RA, Gaieski DF, Abella BS. Therapeutic hypothermia after cardiac arrest in clinical practice: review and compilation of recent experiences. Crit Care Med. 2009 Jul; 37(7 Suppl):S223-6. PMID: 19535950.
      Citations:    
    127. Mikkelsen ME, Miltiades AN, Gaieski DF, Goyal M, Fuchs BD, Shah CV, Bellamy SL, Christie JD. Serum lactate is associated with mortality in severe sepsis independent of organ failure and shock. Crit Care Med. 2009 May; 37(5):1670-7. PMID: 19325467.
      Citations:    
    128. Gaieski DF, Band RA, Abella BS, Neumar RW, Fuchs BD, Kolansky DM, Merchant RM, Carr BG, Becker LB, Maguire C, Klair A, Hylton J, Goyal M. Early goal-directed hemodynamic optimization combined with therapeutic hypothermia in comatose survivors of out-of-hospital cardiac arrest. Resuscitation. 2009 Apr; 80(4):418-24. PMID: 19217200.
      Citations:    
    129. Peacock WF, Fonarow GC, Ander DS, Collins SP, Gheorghiade M, Kirk JD, Filippatos G, Diercks DB, Trupp RJ, Hiestand B, Amsterdam EA, Abraham WT, Amsterdam EA, Dodge G, Gaieski DF, Gurney D, Hayes CO, Hollander JE, Holmes K, Januzzi JL, Levy P, Maisel A, Miller CD, Pang PS, Selby E, Storrow AB, Weintraub NL, Yancy CW, Bahr RD, Blomkalns AL, McCord J, Nowak RM, Stomel RJ. Society of Chest Pain Centers recommendations for the evaluation and management of the observation stay acute heart failure patient-parts 1-6. Acute Card Care. 2009; 11(1):3-42. PMID: 19396642.
      Citations:    
    130. Shapiro NI, Trzeciak S, Hollander JE, Birkhahn R, Otero R, Osborn TM, Moretti E, Nguyen HB, Gunnerson KJ, Milzman D, Gaieski DF, Goyal M, Cairns CB, Ngo L, Rivers EP. A prospective, multicenter derivation of a biomarker panel to assess risk of organ dysfunction, shock, and death in emergency department patients with suspected sepsis. Crit Care Med. 2009 Jan; 37(1):96-104. PMID: 19050610.
      Citations:    
    131. Carr BG, Goyal M, Band RA, Gaieski DF, Abella BS, Merchant RM, Branas CC, Becker LB, Neumar RW. A national analysis of the relationship between hospital factors and post-cardiac arrest mortality. Intensive Care Med. 2009 Mar; 35(3):505-11. PMID: 18936907.
      Citations:    
    132. Band RA, Gaieski DF, Goyal M, Perrone J. A 52-year-old man with malaise and a petechial rash. J Emerg Med. 2011 Jul; 41(1):39-42. PMID: 18722741.
      Citations:    
    133. Goyal M, Pines JM, Drumheller BC, Gaieski DF. Point-of-care testing at triage decreases time to lactate level in septic patients. J Emerg Med. 2010 Jun; 38(5):578-81. PMID: 18614319.
      Citations:    
    134. Perrone J, Phillips C, Gaieski D. Occult metformin toxicity in three patients with profound lactic acidosis. J Emerg Med. 2011 Mar; 40(3):271-5. PMID: 18571361.
      Citations:    
    135. Carr BG, Weisbein JL, Gaieski DF. Salmonella meningitis in an immunocompetent adult. J Emerg Med. 2011 Mar; 40(3):267-70. PMID: 18534805.
      Citations:    
    136. Gaieski DF, Mehta S, Hollander JE, Shofer F, Bernstein J. Low-severity musculoskeletal complaints evaluated in the emergency department. Clin Orthop Relat Res. 2008 Aug; 466(8):1987-95. PMID: 18496728.
      Citations:    
    137. Sankoff JD, Goyal M, Gaieski DF, Deitch K, Davis CB, Sabel AL, Haukoos JS. Validation of the Mortality in Emergency Department Sepsis (MEDS) score in patients with the systemic inflammatory response syndrome (SIRS). Crit Care Med. 2008 Feb; 36(2):421-6. PMID: 18091538.
      Citations:    
    138. Vining DK, Gaieski DF. Pushing the body's limits. Medical emergencies associated with endurance athletics. JEMS. 2007 Jul; 32(7):44-51, 53. PMID: 17631206.
      Citations:    
    139. Band RA, Gaieski DF, Mills AM, Sease KL, Shofer FS, Robey JL, Hollander JE. Discordance between serum creatinine and creatinine clearance for identification of ED patients with abdominal pain at risk for contrast-induced nephropathy. Am J Emerg Med. 2007 Mar; 25(3):268-72. PMID: 17349899.
      Citations:    
    140. Otero RM, Nguyen HB, Huang DT, Gaieski DF, Goyal M, Gunnerson KJ, Trzeciak S, Sherwin R, Holthaus CV, Osborn T, Rivers EP. Early goal-directed therapy in severe sepsis and septic shock revisited: concepts, controversies, and contemporary findings. Chest. 2006 Nov; 130(5):1579-95. PMID: 17099041.
      Citations:    
    141. Gaieski D, Goyal M. The implementation of new therapies for severe sepsis: some questions raised by "early goal-directed therapy, corticosteroid, and recombinant human activated protein c for the treatment of severe sepsis and septic shock in the emergency department". Acad Emerg Med. 2006 Sep; 13(9):997-9; author reply 999-1000. PMID: 16825672.
      Citations:    
    142. Gaieski DF, Goyal M. Serum lactate as a predictor of mortality in emergency department patients with infection: does the lactate level tell the whole story? Ann Emerg Med. 2005 Dec; 46(6):561-2; author reply 562. PMID: 16308078.
      Citations:    
    143. Goyal M, Hollander JE, Gaieski DF. Images in emergency medicine. Synypnea. Ann Emerg Med. 2005 Nov; 46(5):469. PMID: 16271679.
      Citations:    
    144. Insko EK, Gracias VH, Gupta R, Goettler CE, Gaieski DF, Dalinka MK. Utility of flexion and extension radiographs of the cervical spine in the acute evaluation of blunt trauma. J Trauma. 2002 Sep; 53(3):426-9. PMID: 12352475.
      Citations:    
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