Tonio Pera

TitleAsst Professor
InstitutionThomas Jefferson University
DepartmentCenter for Translational Medic
Address1020 Locust St.
Philadelphia PA 19107
Phone215-503-5127
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Prabhala P, Wright DB, Robbe P, Bitter C, Pera T, Ten Hacken NHT, van den Berg M, Timens W, Meurs H, Dekkers BGJ. Laminin a4 contributes to airway remodeling and inflammation in asthma. Am J Physiol Lung Cell Mol Physiol. 2019 Sep 25. PMID: 31553662.
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    2. Pera T, Tompkins E, Katz M, Wang B, Deshpande DA, Weinman EJ, Penn RB. Specificity of NHERF1 regulation of GPCR signaling and function in human airway smooth muscle. FASEB J. 2019 May 01; fj201900323R. PMID: 31042404.
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    3. Nayak AP, Pera T, Deshpande DA, Michael JV, Liberato JR, Pan S, Tompkins E, Morelli HP, Yi R, Wang N, Penn RB. Regulation of Ovarian cancer G protein-coupled receptor (OGR1) expression and signaling. Am J Physiol Lung Cell Mol Physiol. 2019 Feb 06. PMID: 30724097.
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    4. Michael JV, Gavrila A, Nayak AP, Pera T, Liberato JR, Polischak SR, Shah SD, Deshpande DA, Penn RB. Cooperativity of E-prostanoid receptor subtypes in regulating signaling and growth inhibition in human airway smooth muscle. FASEB J. 2019 Jan 02; fj201801959R. PMID: 30601680.
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    5. Pera T, Penn RB. Methods to Investigate ß-Arrestin-Mediated Regulation of GPCR Function in Human Airway Smooth Muscle. Methods Mol Biol. 2019; 1957:69-82. PMID: 30919347.
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    6. Panettieri RA, Pera T, Liggett SB, Benovic JL, Penn RB. Pepducins as a potential treatment strategy for asthma and COPD. Curr Opin Pharmacol. 2018 Jun; 40:120-125. PMID: 29729548.
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    7. Pera T, Deshpande DA, Ippolito M, Wang B, Gavrila A, Michael JV, Nayak AP, Tompkins E, Farrell E, Kroeze WK, Roth BL, Panettieri RA, Benovic JL, An SS, Dulin NO, Penn RB. Biased signaling of the proton-sensing receptor OGR1 by benzodiazepines. FASEB J. 2018 Feb; 32(2):862-874. PMID: 29042451.
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    8. Forkuo GS, Kim H, Thanawala VJ, Al-Sawalha N, Valdez D, Joshi R, Parra S, Pera T, Gonnella PA, Knoll BJ, Walker JK, Penn RB, Bond RA. Phosphodiesterase 4 Inhibitors Attenuate the Asthma Phenotype Produced by ß2-Adrenoceptor Agonists in Phenylethanolamine N-Methyltransferase-Knockout Mice. Am J Respir Cell Mol Biol. 2016 Aug; 55(2):234-42. PMID: 26909542.
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    9. Pera T, Penn RB. Bronchoprotection and bronchorelaxation in asthma: New targets, and new ways to target the old ones. Pharmacol Ther. 2016 Aug; 164:82-96. PMID: 27113408.
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    10. Sharma P, Panebra A, Pera T, Tiegs BC, Hershfeld A, Kenyon LC, Deshpande DA. Antimitogenic effect of bitter taste receptor agonists on airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2016 Feb 15; 310(4):L365-76. PMID: 26684251.
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    11. Pera T, Hegde A, Deshpande DA, Morgan SJ, Tiegs BC, Theriot BS, Choi YH, Walker JK, Penn RB. Specificity of arrestin subtypes in regulating airway smooth muscle G protein-coupled receptor signaling and function. FASEB J. 2015 Oct; 29(10):4227-35. PMID: 26103985.
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    12. Chen X, Walther FJ, Sengers RM, Laghmani el H, Salam A, Folkerts G, Pera T, Wagenaar GT. Metformin attenuates hyperoxia-induced lung injury in neonatal rats by reducing the inflammatory response. Am J Physiol Lung Cell Mol Physiol. 2015 Aug 01; 309(3):L262-70. PMID: 26047641; PMCID: PMC4525117.
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    13. Noble PB, Pascoe CD, Lan B, Ito S, Kistemaker LE, Tatler AL, Pera T, Brook BS, Gosens R, West AR. Airway smooth muscle in asthma: linking contraction and mechanotransduction to disease pathogenesis and remodelling. Pulm Pharmacol Ther. 2014 Dec; 29(2):96-107. PMID: 25062835.
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    14. Pera T, Penn RB. Crosstalk between beta-2-adrenoceptor and muscarinic acetylcholine receptors in the airway. Curr Opin Pharmacol. 2014 Jun; 16:72-81. PMID: 24747364.
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    15. Deshpande DA, Yan H, Kong KC, Tiegs BC, Morgan SJ, Pera T, Panettieri RA, Eckhart AD, Penn RB. Exploiting functional domains of GRK2/3 to alter the competitive balance of pro- and anticontractile signaling in airway smooth muscle. FASEB J. 2014 Feb; 28(2):956-65. PMID: 24132623.
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    16. van der Veer EP, de Bruin RG, Kraaijeveld AO, de Vries MR, Bot I, Pera T, Segers FM, Trompet S, van Gils JM, Roeten MK, Beckers CM, van Santbrink PJ, Janssen A, van Solingen C, Swildens J, de Boer HC, Peters EA, Bijkerk R, Rousch M, Doop M, Kuiper J, Schalij MJ, van der Wal AC, Richard S, van Berkel TJ, Pickering JG, Hiemstra PS, Goumans MJ, Rabelink TJ, de Vries AA, Quax PH, Jukema JW, Biessen EA, van Zonneveld AJ. Quaking, an RNA-binding protein, is a critical regulator of vascular smooth muscle cell phenotype. Circ Res. 2013 Oct 12; 113(9):1065-75. PMID: 23963726.
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    17. Pera T, Atmaj C, van der Vegt M, Halayko AJ, Zaagsma J, Meurs H. Role for TAK1 in cigarette smoke-induced proinflammatory signaling and IL-8 release by human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2012 Aug 01; 303(3):L272-8. PMID: 22523282.
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    18. Pera T, Sami R, Zaagsma J, Meurs H. TAK1 plays a major role in growth factor-induced phenotypic modulation of airway smooth muscle. Am J Physiol Lung Cell Mol Physiol. 2011 Nov; 301(5):L822-8. PMID: 21873447.
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    19. Pera T, Gosens R, Lesterhuis AH, Sami R, van der Toorn M, Zaagsma J, Meurs H. Cigarette smoke and lipopolysaccharide induce a proliferative airway smooth muscle phenotype. Respir Res. 2010 Apr 29; 11:48. PMID: 20429916; PMCID: PMC2873257.
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    20. Maarsingh H, Pera T, Meurs H. Arginase and pulmonary diseases. Naunyn Schmiedebergs Arch Pharmacol. 2008 Aug; 378(2):171-84. PMID: 18437360; PMCID: PMC2493601.
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    21. Gosens R, Roscioni SS, Dekkers BG, Pera T, Schmidt M, Schaafsma D, Zaagsma J, Meurs H. Pharmacology of airway smooth muscle proliferation. Eur J Pharmacol. 2008 May 13; 585(2-3):385-97. PMID: 18417114.
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