John Patton

TitleAdjunct Faculty
InstitutionThomas Jefferson University
DepartmentJefferson College of Life Scie
Address1020 Locust St.
Philadelphia PA 19107
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. George PJ, Hess JA, Jain S, Patton JB, Zhan T, Tricoche N, Zhan B, Bottazzi ME, Hotez PJ, Abraham D, Lustigman S. Antibody responses against the vaccine antigens Ov-103 and Ov-RAL-2 are associated with protective immunity to Onchocerca volvulus infection in both mice and humans. PLoS Negl Trop Dis. 2019 Sep; 13(9):e0007730. PMID: 31525197.
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    2. Patton JB, Bennuru S, Eberhard ML, Hess JA, Torigian A, Lustigman S, Nutman TB, Abraham D. Development of Onchocerca volvulus in humanized NSG mice and detection of parasite biomarkers in urine and serum. PLoS Negl Trop Dis. 2018 12; 12(12):e0006977. PMID: 30540742.
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    3. Patton JB, Bonne-Année S, Deckman J, Hess JA, Torigian A, Nolan TJ, Wang Z, Kliewer SA, Durham AC, Lee JJ, Eberhard ML, Mangelsdorf DJ, Lok JB, Abraham D. Methylprednisolone acetate induces, and ?7-dafachronic acid suppresses, Strongyloides stercoralis hyperinfection in NSG mice. Proc Natl Acad Sci U S A. 2018 01 02; 115(1):204-209. PMID: 29203662.
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    4. Hess JA, Zhan B, Torigian AR, Patton JB, Petrovsky N, Zhan T, Bottazzi ME, Hotez PJ, Klei TR, Lustigman S, Abraham D. The Immunomodulatory Role of Adjuvants in Vaccines Formulated with the Recombinant Antigens Ov-103 and Ov-RAL-2 against Onchocerca volvulus in Mice. PLoS Negl Trop Dis. 2016 Jul; 10(7):e0004797. PMID: 27387453.
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    5. Patton J, Vuyyuru R, Siglin A, Root M, Manser T. Evaluation of the efficiency of human immune system reconstitution in NSG mice and NSG mice containing a human HLA.A2 transgene using hematopoietic stem cells purified from different sources. J Immunol Methods. 2015 Jul; 422:13-21. PMID: 25776756.
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    6. Landel CP, Dunlap J, Patton JB, Manser T. A germline-competent embryonic stem cell line from NOD.Cg-Prkdc ( scid ) Il2rg ( tm1Wjl )/SzJ (NSG) mice. Transgenic Res. 2013 Feb; 22(1):179-85. PMID: 22767020.
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    7. Vuyyuru R, Patton J, Manser T. Human immune system mice: current potential and limitations for translational research on human antibody responses. Immunol Res. 2011 Dec; 51(2-3):257-66. PMID: 22038527.
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    8. Lawson SR, Li Y, Patton JB, Langenhorst RJ, Sun Z, Jiang Z, Christopher-Hennings J, Nelson EA, Knudsen D, Fang Y, Chang KO. Interleukin-1ß expression by a recombinant porcine reproductive and respiratory syndrome virus. Virus Res. 2012 Feb; 163(2):461-8. PMID: 22119401.
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    9. Patton JB, George D, Chang KO. Bile acids promote HCV replication through the EGFR/ERK pathway in replicon-harboring cells. Intervirology. 2011; 54(6):339-48. PMID: 21293096.
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    10. Patton JB, Rowland RR, Yoo D, Chang KO. Modulation of CD163 receptor expression and replication of porcine reproductive and respiratory syndrome virus in porcine macrophages. Virus Res. 2009 Mar; 140(1-2):161-71. PMID: 19111584.
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    11. Chang KO, George DW, Patton JB, Green KY, Sosnovtsev SV. Leader of the capsid protein in feline calicivirus promotes replication of Norwalk virus in cell culture. J Virol. 2008 Oct; 82(19):9306-17. PMID: 18632864.
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