Heparan Sulfate Proteoglycans
"Heparan Sulfate Proteoglycans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Ubiquitous macromolecules associated with the cell surface and extracellular matrix of a wide range of cells of vertebrate and invertebrate tissues. They are essential cofactors in cell-matrix adhesion processes, in cell-cell recognition systems, and in receptor-growth factor interactions. (From Cancer Metastasis Rev 1996; 15(2): 177-86; Hepatology 1996; 24(3): 524-32)
| Descriptor ID |
D019812
|
| MeSH Number(s) |
D09.698.373.425.500 D09.698.735.400 D12.776.395.650.350
|
| Concept/Terms |
Heparan Sulfate Proteoglycans- Heparan Sulfate Proteoglycans
- Proteoglycans, Heparan Sulfate
- Sulfate Proteoglycans, Heparan
- HSPG
- Proteoheparan Sulfate
- Heparan Sulfate Proteoglycan
- Proteoglycan, Heparan Sulfate
|
Below are MeSH descriptors whose meaning is more general than "Heparan Sulfate Proteoglycans".
Below are MeSH descriptors whose meaning is more specific than "Heparan Sulfate Proteoglycans".
This graph shows the total number of publications written about "Heparan Sulfate Proteoglycans" by people in this website by year, and whether "Heparan Sulfate Proteoglycans" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 0 | 1 | 1 |
| 1992 | 0 | 1 | 1 |
| 1993 | 1 | 1 | 2 |
| 1994 | 4 | 0 | 4 |
| 1995 | 1 | 0 | 1 |
| 1996 | 1 | 0 | 1 |
| 1997 | 4 | 0 | 4 |
| 1998 | 3 | 0 | 3 |
| 1999 | 1 | 0 | 1 |
| 2000 | 3 | 1 | 4 |
| 2001 | 4 | 1 | 5 |
| 2002 | 3 | 1 | 4 |
| 2003 | 3 | 0 | 3 |
| 2004 | 4 | 0 | 4 |
| 2005 | 2 | 0 | 2 |
| 2006 | 3 | 0 | 3 |
| 2007 | 2 | 0 | 2 |
| 2008 | 4 | 0 | 4 |
| 2009 | 7 | 0 | 7 |
| 2010 | 3 | 1 | 4 |
| 2011 | 3 | 1 | 4 |
| 2012 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Heparan Sulfate Proteoglycans" by people in Profiles.
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Srinivasan PP, McCoy SY, Jha AK, Yang W, Jia X, Farach-Carson MC, Kirn-Safran CB. Injectable perlecan domain 1-hyaluronan microgels potentiate the cartilage repair effect of BMP2 in a murine model of early osteoarthritis. Biomed Mater. 2012 Apr; 7(2):024109.
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Boggs ME, Thompson WR, Farach-Carson MC, Duncan RL, Beebe TP. Co-culture of osteocytes and neurons on a unique patterned surface. Biointerphases. 2011 Dec; 6(4):200-9.
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Lee B, Clarke D, Al Ahmad A, Kahle M, Parham C, Auckland L, Shaw C, Fidanboylu M, Orr AW, Ogunshola O, Fertala A, Thomas SA, Bix GJ. Perlecan domain V is neuroprotective and proangiogenic following ischemic stroke in rodents. J Clin Invest. 2011 Aug; 121(8):3005-23.
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Goyal A, Pal N, Concannon M, Paul M, Doran M, Poluzzi C, Sekiguchi K, Whitelock JM, Neill T, Iozzo RV. Endorepellin, the angiostatic module of perlecan, interacts with both the a2ß1 integrin and vascular endothelial growth factor receptor 2 (VEGFR2): a dual receptor antagonism. J Biol Chem. 2011 Jul 22; 286(29):25947-62.
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Thompson WR, Modla S, Grindel BJ, Czymmek KJ, Kirn-Safran CB, Wang L, Duncan RL, Farach-Carson MC. Perlecan/Hspg2 deficiency alters the pericellular space of the lacunocanalicular system surrounding osteocytic processes in cortical bone. J Bone Miner Res. 2011 Mar; 26(3):618-29.
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Muthusamy A, Cooper CR, Gomes RR. Soluble perlecan domain I enhances vascular endothelial growth factor-165 activity and receptor phosphorylation in human bone marrow endothelial cells. BMC Biochem. 2010; 11:43.
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Chuang CY, Lord MS, Melrose J, Rees MD, Knox SM, Freeman C, Iozzo RV, Whitelock JM. Heparan sulfate-dependent signaling of fibroblast growth factor 18 by chondrocyte-derived perlecan. Biochemistry. 2010 Jul 6; 49(26):5524-32.
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Hartman O, Zhang C, Adams EL, Farach-Carson MC, Petrelli NJ, Chase BD, Rabolt JF. Biofunctionalization of electrospun PCL-based scaffolds with perlecan domain IV peptide to create a 3-D pharmacokinetic cancer model. Biomaterials. 2010 Jul; 31(21):5700-18.
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Pradhan S, Liu C, Zhang C, Jia X, Farach-Carson MC, Witt RL. Lumen formation in three-dimensional cultures of salivary acinar cells. Otolaryngol Head Neck Surg. 2010 Feb; 142(2):191-5.
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Pradhan S, Zhang C, Jia X, Carson DD, Witt R, Farach-Carson MC. Perlecan domain IV peptide stimulates salivary gland cell assembly in vitro. Tissue Eng Part A. 2009 Nov; 15(11):3309-20.