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Steven Roberts

TitleAsst Professor
InstitutionThomas Jefferson University
DepartmentCardiology
Address9501 Roosevelt Boulevard
Philadelphia PA 19114
Phone215-676-8300
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    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. DiVito KA, Daniele MA, Roberts SA, Ligler FS, Adams AA. "Data characterizing microfabricated human blood vessels created via hydrodynamic focusing". Data Brief. 2017 Oct; 14:156-162. PMID: 28795092.
      View in: PubMed
    2. DiVito KA, Daniele MA, Roberts SA, Ligler FS, Adams AA. Microfabricated blood vessels undergo neoangiogenesis. Biomaterials. 2017 Sep; 138:142-152. PMID: 28570946.
      View in: PubMed
    3. Saini N, Roberts SA, Sterling JF, Malc EP, Mieczkowski PA, Gordenin DA. APOBEC3B cytidine deaminase targets the non-transcribed strand of tRNA genes in yeast. DNA Repair (Amst). 2017 May; 53:4-14. PMID: 28351647.
      View in: PubMed
    4. Mertz TM, Harcy V, Roberts SA. Risks at the DNA Replication Fork: Effects upon Carcinogenesis and Tumor Heterogeneity. Genes (Basel). 2017 Jan 22; 8(1). PMID: 28117753.
      View in: PubMed
    5. Saini N, Roberts SA, Klimczak LJ, Chan K, Grimm SA, Dai S, Fargo DC, Boyer JC, Kaufmann WK, Taylor JA, Lee E, Cortes-Ciriano I, Park PJ, Schurman SH, Malc EP, Mieczkowski PA, Gordenin DA. The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts. PLoS Genet. 2016 10; 12(10):e1006385. PMID: 27788131.
      View in: PubMed
    6. Mao P, Wyrick JJ, Roberts SA, Smerdon MJ. UV-Induced DNA Damage and Mutagenesis in Chromatin. Photochem Photobiol. 2016 Sep 26. PMID: 27716995.
      View in: PubMed
    7. Roberts SA, DiVito KA, Ligler FS, Adams AA, Daniele MA. Microvessel manifold for perfusion and media exchange in three-dimensional cell cultures. Biomicrofluidics. 2016 Sep; 10(5):054109. PMID: 27703595.
      View in: PubMed
    8. Mao P, Smerdon MJ, Roberts SA, Wyrick JJ. Chromosomal landscape of UV damage formation and repair at single-nucleotide resolution. Proc Natl Acad Sci U S A. 2016 Aug 9; 113(32):9057-62. PMID: 27457959.
      View in: PubMed
    9. Wyatt DW, Feng W, Conlin MP, Yousefzadeh MJ, Roberts SA, Mieczkowski P, Wood RD, Gupta GP, Ramsden DA. Essential Roles for Polymerase ?-Mediated End Joining in the Repair of Chromosome Breaks. Mol Cell. 2016 Aug 18; 63(4):662-73. PMID: 27453047.
      View in: PubMed
    10. Roberts SA, Waziri AE, Agrawal N. Development of a Single-Cell Migration and Extravasation Platform through Selective Surface Modification. Anal Chem. 2016 Mar 1; 88(5):2770-6. PMID: 26833093.
      View in: PubMed
    11. Kazanov MD, Roberts SA, Polak P, Stamatoyannopoulos J, Klimczak LJ, Gordenin DA, Sunyaev SR. APOBEC-Induced Cancer Mutations Are Uniquely Enriched in Early-Replicating, Gene-Dense, and Active Chromatin Regions. Cell Rep. 2015 Nov 10; 13(6):1103-9. PMID: 26527001.
      View in: PubMed
    12. Wyrick JJ, Roberts SA. Genomic approaches to DNA repair and mutagenesis. DNA Repair (Amst). 2015 Dec; 36:146-55. PMID: 26411877.
      View in: PubMed
    13. Chan K, Roberts SA, Klimczak LJ, Sterling JF, Saini N, Malc EP, Kim J, Kwiatkowski DJ, Fargo DC, Mieczkowski PA, Getz G, Gordenin DA. An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers. Nat Genet. 2015 Sep; 47(9):1067-72. PMID: 26258849.
      View in: PubMed
    14. Daniele MA, Knight AJ, Roberts SA, Radom K, Erickson JS. Sweet substrate: a polysaccharide nanocomposite for conformal electronic decals. Adv Mater. 2015 Mar 4; 27(9):1600-6. PMID: 25472799.
      View in: PubMed
    15. Roberts SA, Gordenin DA. Hypermutation in human cancer genomes: footprints and mechanisms. Nat Rev Cancer. 2014 Dec; 14(12):786-800. PMID: 25568919.
      View in: PubMed
    16. Strande NT, Carvajal-Garcia J, Hallett RA, Waters CA, Roberts SA, Strom C, Kuhlman B, Ramsden DA. Requirements for 5'dRP/AP lyase activity in Ku. Nucleic Acids Res. 2014; 42(17):11136-43. PMID: 25200085.
      View in: PubMed
    17. Sakofsky CJ, Roberts SA, Malc E, Mieczkowski PA, Resnick MA, Gordenin DA, Malkova A. Break-induced replication is a source of mutation clusters underlying kataegis. Cell Rep. 2014 Jun 12; 7(5):1640-8. PMID: 24882007.
      View in: PubMed
    18. Roberts SA, Gordenin DA. Clustered and genome-wide transient mutagenesis in human cancers: Hypermutation without permanent mutators or loss of fitness. Bioessays. 2014 Feb 26. PMID: 24615916.
      View in: PubMed
    19. Roberts SA, Lawrence MS, Klimczak LJ, Grimm SA, Fargo D, Stojanov P, Kiezun A, Kryukov GV, Carter SL, Saksena G, Harris S, Shah RR, Resnick MA, Getz G, Gordenin DA. An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers. Nat Genet. 2013 Sep; 45(9):970-6. PMID: 23852170.
      View in: PubMed
    20. Chan K, Sterling JF, Roberts SA, Bhagwat AS, Resnick MA, Gordenin DA. Base damage within single-strand DNA underlies in vivo hypermutability induced by a ubiquitous environmental agent. PLoS Genet. 2012; 8(12):e1003149. PMID: 23271983.
      View in: PubMed
    21. Roberts SA, Sterling J, Thompson C, Harris S, Mav D, Shah R, Klimczak LJ, Kryukov GV, Malc E, Mieczkowski PA, Resnick MA, Gordenin DA. Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions. Mol Cell. 2012 May 25; 46(4):424-35. PMID: 22607975.
      View in: PubMed
    22. Strande N, Roberts SA, Oh S, Hendrickson EA, Ramsden DA. Specificity of the dRP/AP lyase of Ku promotes nonhomologous end joining (NHEJ) fidelity at damaged ends. J Biol Chem. 2012 Apr 20; 287(17):13686-93. PMID: 22362780.
      View in: PubMed
    23. Burch LH, Yang Y, Sterling JF, Roberts SA, Chao FG, Xu H, Zhang L, Walsh J, Resnick MA, Mieczkowski PA, Gordenin DA. Damage-induced localized hypermutability. Cell Cycle. 2011 Apr 1; 10(7):1073-85. PMID: 21406975.
      View in: PubMed
    24. Roberts SA, Strande N, Burkhalter MD, Strom C, Havener JM, Hasty P, Ramsden DA. Ku is a 5'-dRP/AP lyase that excises nucleotide damage near broken ends. Nature. 2010 Apr 22; 464(7292):1214-7. PMID: 20383123.
      View in: PubMed
    25. Lestner JM, Roberts SA, Moore CB, Howard SJ, Denning DW, Hope WW. Toxicodynamics of itraconazole: implications for therapeutic drug monitoring. Clin Infect Dis. 2009 Sep 15; 49(6):928-30. PMID: 19681707.
      View in: PubMed
    26. Burkhalter MD, Roberts SA, Havener JM, Ramsden DA. Activity of ribonucleotide reductase helps determine how cells repair DNA double strand breaks. DNA Repair (Amst). 2009 Nov 2; 8(11):1258-63. PMID: 19713159.
      View in: PubMed
    27. Roberts SA, Ramsden DA. Loading of the nonhomologous end joining factor, Ku, on protein-occluded DNA ends. J Biol Chem. 2007 Apr 6; 282(14):10605-13. PMID: 17289670.
      View in: PubMed
    28. Ward KA, Ashby RL, Roberts SA, Adams JE, Zulf Mughal M. UK reference data for the Hologic QDR Discovery dual-energy x ray absorptiometry scanner in healthy children and young adults aged 6-17 years. Arch Dis Child. 2007 Jan; 92(1):53-9. PMID: 16943261.
      View in: PubMed
    29. Roberts SA, Guruswamy V, Galvez I. Caudal injectate can be reliably imaged using portable ultrasound--a preliminary study. Paediatr Anaesth. 2005 Nov; 15(11):948-52. PMID: 16238555.
      View in: PubMed
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