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Last Name
Institution

Theodore Christopher

TitleProfessor & Chair JMC
InstitutionThomas Jefferson University
DepartmentChair SKMC
Address1020 Sansom St.
Philadelphia PA 19107
Phone215-955-6844

 Bibliographic 
 selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Du Y, Li R, Lau WB, Zhao J, Lopez B, Christopher TA, Ma XL, Wang Y. Adiponectin at Physiologically Relevant Concentrations Enhances the Vasorelaxative Effect of Acetylcholine via Cav-1/AdipoR-1 Signaling. PLoS One. 2016; 11(3):e0152247.
    View in: PubMed
  2. Yuan Y, Lau WB, Su H, Sun Y, Yi W, Du Y, Christopher T, Lopez B, Wang Y, Ma XL. C1q-TNF-related protein-9, a novel cardioprotetcive cardiokine, requires proteolytic cleavage to generate a biologically active globular domain isoform. Am J Physiol Endocrinol Metab. 2015 May 15; 308(10):E891-8.
    View in: PubMed
  3. Beeson MS, Carter WA, Christopher TA, Heidt JW, Jones JH, Meyer LE, Promes SB, Rodgers KG, Shayne PH, Swing SR, Wagner MJ. The development of the emergency medicine milestones. Acad Emerg Med. 2013 Jul; 20(7):724-9.
    View in: PubMed
  4. Beeson MS, Carter WA, Christopher TA, Heidt JW, Jones JH, Meyer LE, Promes SB, Rodgers KG, Shayne PH, Wagner MJ, Swing SR. Emergency medicine milestones. J Grad Med Educ. 2013 Mar; 5(1 Suppl 1):5-13.
    View in: PubMed
  5. Lau WB, Zhang Y, Zhao J, Liu B, Wang X, Yuan Y, Christopher TA, Lopez B, Gao E, Koch WJ, Ma XL, Wang Y. Lymphotoxin-a is a novel adiponectin expression suppressor following myocardial ischemia/reperfusion. Am J Physiol Endocrinol Metab. 2013 Mar; 304(6):E661-7.
    View in: PubMed
  6. Zheng Q, Yuan Y, Yi W, Lau WB, Wang Y, Wang X, Sun Y, Lopez BL, Christopher TA, Peterson JM, Wong GW, Yu S, Yi D, Ma XL. C1q/TNF-related proteins, a family of novel adipokines, induce vascular relaxation through the adiponectin receptor-1/AMPK/eNOS/nitric oxide signaling pathway. Arterioscler Thromb Vasc Biol. 2011 Nov; 31(11):2616-23.
    View in: PubMed
  7. Rogers RL, Wald DA, Lin M, Zun LS, Christopher T, Manthey DE. Expectations of an emergency medicine clerkship director. Acad Emerg Med. 2011 May; 18(5):513-8.
    View in: PubMed
  8. Wald DA, Lin M, Manthey DE, Rogers RL, Zun LS, Christopher T. Emergency medicine in the medical school curriculum. Acad Emerg Med. 2010 Oct; 17 Suppl 2:S26-30.
    View in: PubMed
  9. Schneider SM, Gardner AF, Weiss LD, Wood JP, Ybarra M, Beck DM, Stauffer AR, Wilkerson D, Brabson T, Jennings A, Mitchell M, McGrath RB, Christopher TA, King B, Muelleman RL, Wagner MJ, Char DM, McGee DL, Pilgrim RL, Moskovitz JB, Zinkel AR, Byers M, Briggs WT, Hobgood CD, Kupas DF, Kruger J, Stratford CJ, Jouriles N. The future of emergency medicine. Acad Emerg Med. 2010 Sep; 17(9):998-1003.
    View in: PubMed
  10. Schneider SM, Gardner AF, Weiss LD, Wood JP, Ybarra M, Beck DM, Stauffer AR, Wilkerson D, Brabson T, Jennings A, Mitchell M, McGrath RB, Christopher TA, King B, Muelleman RL, Wagner MJ, Char DM, McGee DL, Pilgrim RL, Moskovitz JB, Zinkel AR, Byers M, Briggs WT, Hobgood CD, Kupas DF, Krueger J, Stratford CJ, Jouriles NJ. The future of emergency medicine. J Emerg Med. 2010 Aug; 39(2):210-5.
    View in: PubMed
  11. Schneider SM, Gardner AF, Weiss LD, Wood JP, Ybarra M, Beck DM, Stauffer AR, Wilkerson D, Brabson T, Jennings A, Mitchell M, McGrath RB, Christopher TA, King B, Muelleman RL, Wagner MJ, Char DM, McGee DL, Pilgrim RL, Moskovitz JB, Zinkel AR, Byers M, Briggs WT, Hobgood CD, Kupas DF, Kruger J, Stratford CJ, Jouriles N. The future of emergency medicine. J Emerg Nurs. 2010 Jul; 36(4):330-5.
    View in: PubMed
  12. Schneider SM, Gardner AF, Weiss LD, Wood JP, Ybarra M, Beck DM, Stauffer AR, Wilkerson D, Brabson T, Jennings A, Mitchell M, McGrath RB, Christopher TA, King B, Muelleman RL, Wagner MJ, Char DM, McGee DL, Pilgrim RL, Moskovitz JB, Zinkel AR, Byers M, Briggs WT, Hobgood CD, Kupas DF, Kruger J, Stratford CJ, Jouriles N. The future of emergency medicine. Ann Emerg Med. 2010 Aug; 56(2):178-83.
    View in: PubMed
  13. Wang XL, Lau WB, Yuan YX, Wang YJ, Yi W, Christopher TA, Lopez BL, Liu HR, Ma XL. Methylglyoxal increases cardiomyocyte ischemia-reperfusion injury via glycative inhibition of thioredoxin activity. Am J Physiol Endocrinol Metab. 2010 Aug; 299(2):E207-14.
    View in: PubMed
  14. Yuan Y, Jiao X, Lau WB, Wang Y, Christopher TA, Lopez BL, Ramachandrarao SP, Tao L, Ma XL. Thioredoxin glycation: A novel posttranslational modification that inhibits its antioxidant and organ protective actions. Free Radic Biol Med. 2010 Aug 1; 49(3):332-8.
    View in: PubMed
  15. Li R, Xu M, Wang X, Wang Y, Lau WB, Yuan Y, Yi W, Wei X, Lopez BL, Christopher TA, Wang XM, Ma XL. Reduced vascular responsiveness to adiponectin in hyperlipidemic rats--mechanisms and significance. J Mol Cell Cardiol. 2010 Sep; 49(3):508-15.
    View in: PubMed
  16. Chen G, Lai W, Liu F, Mao Q, Tu F, Wen J, Xiao H, Zhang JC, Zhu T, Chen B, Hu ZY, Li RM, Liang Z, Nie H, Yan H, Yang BX, Du Q, Huang WX, Jiang YW, Kwan AS, Song L, Wu CM, Xiang T, Xu HW, Lau WB, Song HB, Wen CB, Yao ZH, Zhang L, Zeng J, Dai YE, Lopez BL, Zheng JQ, Zhou J, Christopher TA, Ma XL, Yu H, Xu LL, Guo Q, Song ZP, Volinn E, Kryger K, Cao Y, Ge H, Liu H, Luo CZ, Tao W, Zuo YX, Liu J. The dragon strikes: lessons from the Wenchuan earthquake. Anesth Analg. 2010 Mar 1; 110(3):908-15.
    View in: PubMed
  17. Nie H, Tang SY, Lau WB, Zhang JC, Jiang YW, Lopez BL, Ma XL, Cao Y, Christopher TA. Triage during the week of the Sichuan earthquake: a review of utilized patient triage, care, and disposition procedures. Injury. 2011 May; 42(5):515-20.
    View in: PubMed
  18. Hemphill RR, Sklar DP, Christopher T, Kellermann AL, Tarrant JR. Emergency medicine and political influence. Acad Emerg Med. 2009 Oct; 16(10):1019-24.
    View in: PubMed
  19. Wang Y, Tao L, Yuan Y, Lau WB, Li R, Lopez BL, Christopher TA, Tian R, Ma XL. Cardioprotective effect of adiponectin is partially mediated by its AMPK-independent antinitrative action. Am J Physiol Endocrinol Metab. 2009 Aug; 297(2):E384-91.
    View in: PubMed
  20. Wang Y, Gao E, Tao L, Lau WB, Yuan Y, Goldstein BJ, Lopez BL, Christopher TA, Tian R, Koch W, Ma XL. AMP-activated protein kinase deficiency enhances myocardial ischemia/reperfusion injury but has minimal effect on the antioxidant/antinitrative protection of adiponectin. Circulation. 2009 Feb 17; 119(6):835-44.
    View in: PubMed
  21. Liu HR, Tao L, Gao E, Qu Y, Lau WB, Lopez BL, Christopher TA, Koch W, Yue TL, Ma XL. Rosiglitazone inhibits hypercholesterolaemia-induced myeloperoxidase upregulation--a novel mechanism for the cardioprotective effects of PPAR agonists. Cardiovasc Res. 2009 Feb 1; 81(2):344-52.
    View in: PubMed
  22. Cao Y, Tao L, Yuan Y, Jiao X, Lau WB, Wang Y, Christopher T, Lopez B, Chan L, Goldstein B, Ma XL. Endothelial dysfunction in adiponectin deficiency and its mechanisms involved. J Mol Cell Cardiol. 2009 Mar; 46(3):413-9.
    View in: PubMed
  23. Zhang H, Li J, Li R, Zhang Q, Ma H, Ji Q, Guo W, Wang H, Lopez BL, Christopher TA, Ma X, Gao F. Reduced cardiotropic response to insulin in spontaneously hypertensive rats: role of peroxisome proliferator-activated receptor-gamma-initiated signaling. J Hypertens. 2008 Mar; 26(3):560-9.
    View in: PubMed
  24. Li S, Tao L, Jiao X, Liu H, Cao Y, Lopez B, Luan RH, Christopher T, Ma XL. TNFalpha-initiated oxidative/nitrative stress mediates cardiomyocyte apoptosis in traumatic animals. Apoptosis. 2007 Oct; 12(10):1795-802.
    View in: PubMed
  25. Li R, Wang WQ, Zhang H, Yang X, Fan Q, Christopher TA, Lopez BL, Tao L, Goldstein BJ, Gao F, Ma XL. Adiponectin improves endothelial function in hyperlipidemic rats by reducing oxidative/nitrative stress and differential regulation of eNOS/iNOS activity. Am J Physiol Endocrinol Metab. 2007 Dec; 293(6):E1703-8.
    View in: PubMed
  26. Li S, Jiao X, Tao L, Liu H, Cao Y, Lopez BL, Christopher TA, Ma XL. Tumor necrosis factor-alpha in mechanic trauma plasma mediates cardiomyocyte apoptosis. Am J Physiol Heart Circ Physiol. 2007 Sep; 293(3):H1847-52.
    View in: PubMed
  27. Wang XL, Liu HR, Tao L, Liang F, Yan L, Zhao RR, Lopez BL, Christopher TA, Ma XL. Role of iNOS-derived reactive nitrogen species and resultant nitrative stress in leukocytes-induced cardiomyocyte apoptosis after myocardial ischemia/reperfusion. Apoptosis. 2007 Jul; 12(7):1209-17.
    View in: PubMed
  28. Huang Z, Shi G, Gao F, Zhang Y, Liu X, Christopher TA, Lopez B, Ma X. Effects of N-n-butyl haloperidol iodide on L-type calcium channels and intracellular free calcium in rat ventricular myocytes. Biochem Cell Biol. 2007 Apr; 85(2):182-8.
    View in: PubMed
  29. Zhang H, Tao L, Jiao X, Gao E, Lopez BL, Christopher TA, Koch W, Ma XL. Nitrative thioredoxin inactivation as a cause of enhanced myocardial ischemia/reperfusion injury in the aging heart. Free Radic Biol Med. 2007 Jul 1; 43(1):39-47.
    View in: PubMed
  30. Tao L, Gao E, Jiao X, Yuan Y, Li S, Christopher TA, Lopez BL, Koch W, Chan L, Goldstein BJ, Ma XL. Adiponectin cardioprotection after myocardial ischemia/reperfusion involves the reduction of oxidative/nitrative stress. Circulation. 2007 Mar 20; 115(11):1408-16.
    View in: PubMed
  31. Tao L, Jiao X, Gao E, Lau WB, Yuan Y, Lopez B, Christopher T, RamachandraRao SP, Williams W, Southan G, Sharma K, Koch W, Ma XL. Nitrative inactivation of thioredoxin-1 and its role in postischemic myocardial apoptosis. Circulation. 2006 Sep 26; 114(13):1395-402.
    View in: PubMed
  32. Wang HC, Zhang HF, Guo WY, Su H, Zhang KR, Li QX, Yan W, Ma XL, Lopez BL, Christopher TA, Gao F. Hypoxic postconditioning enhances the survival and inhibits apoptosis of cardiomyocytes following reoxygenation: role of peroxynitrite formation. Apoptosis. 2006 Aug; 11(8):1453-60.
    View in: PubMed
  33. Manthey DE, Coates WC, Ander DS, Ankel FK, Blumstein H, Christopher TA, Courtney JM, Hamilton GC, Kaiyala EK, Rodgers K, Schneir AB, Thomas SH. Report of the Task Force on National Fourth Year Medical Student Emergency Medicine Curriculum Guide. Ann Emerg Med. 2006 Mar; 47(3):e1-7.
    View in: PubMed
  34. Tao L, Liu HR, Gao F, Qu Y, Christopher TA, Lopez BL, Ma XL. Mechanical traumatic injury without circulatory shock causes cardiomyocyte apoptosis: role of reactive nitrogen and reactive oxygen species. Am J Physiol Heart Circ Physiol. 2005 Jun; 288(6):H2811-8.
    View in: PubMed
  35. Liu HR, Gao E, Hu A, Tao L, Qu Y, Most P, Koch WJ, Christopher TA, Lopez BL, Alnemri ES, Zervos AS, Ma XL. Role of Omi/HtrA2 in apoptotic cell death after myocardial ischemia and reperfusion. Circulation. 2005 Jan 4; 111(1):90-6.
    View in: PubMed
  36. Tao L, Gao E, Bryan NS, Qu Y, Liu HR, Hu A, Christopher TA, Lopez BL, Yodoi J, Koch WJ, Feelisch M, Ma XL. Cardioprotective effects of thioredoxin in myocardial ischemia and reperfusion: role of S-nitrosation [corrected]. Proc Natl Acad Sci U S A. 2004 Aug 3; 101(31):11471-6.
    View in: PubMed
  37. Liang F, Gao E, Tao L, Liu H, Qu Y, Christopher TA, Lopez BL, Ma XL. Critical timing of L-arginine treatment in post-ischemic myocardial apoptosis-role of NOS isoforms. Cardiovasc Res. 2004 Jun 1; 62(3):568-77.
    View in: PubMed
  38. Liu HR, Gao F, Tao L, Yan WL, Gao E, Christopher TA, Lopez BL, Hu A, Ma XL. Antiapoptotic mechanisms of benidipine in the ischemic/reperfused heart. Br J Pharmacol. 2004 Jun; 142(4):627-34.
    View in: PubMed
  39. Liu HR, Tao L, Gao E, Lopez BL, Christopher TA, Willette RN, Ohlstein EH, Yue TL, Ma XL. Anti-apoptotic effects of rosiglitazone in hypercholesterolemic rabbits subjected to myocardial ischemia and reperfusion. Cardiovasc Res. 2004 Apr 1; 62(1):135-44.
    View in: PubMed
  40. Tao L, Liu HR, Gao E, Teng ZP, Lopez BL, Christopher TA, Ma XL, Batinic-Haberle I, Willette RN, Ohlstein EH, Yue TL. Antioxidative, antinitrative, and vasculoprotective effects of a peroxisome proliferator-activated receptor-gamma agonist in hypercholesterolemia. Circulation. 2003 Dec 2; 108(22):2805-11.
    View in: PubMed
  41. Lopez BL, Davis-Moon L, Sterious W, Bulette M, Liang-Ma X, Christopher TA. The Power Infuser: a new device for rapid fluid infusion. Am J Emerg Med. 2003 Mar; 21(2):129-32.
    View in: PubMed
  42. Christopher TA, Lopez BL, Stillwagon JC, Gao F, Gao E, Ma XL, Ohlstein EH, Yue TL. Idoxifene causes endothelium-dependent, nitric oxide-mediated vasorelaxation in male rats. Eur J Pharmacol. 2002 Jun 20; 446(1-3):139-43.
    View in: PubMed
  43. Gao F, Yao CL, Gao E, Mo QZ, Yan WL, McLaughlin R, Lopez BL, Christopher TA, Ma XL. Enhancement of glutathione cardioprotection by ascorbic acid in myocardial reperfusion injury. J Pharmacol Exp Ther. 2002 May; 301(2):543-50.
    View in: PubMed
  44. Gao F, Gao E, Yue TL, Ohlstein EH, Lopez BL, Christopher TA, Ma XL. Nitric oxide mediates the antiapoptotic effect of insulin in myocardial ischemia-reperfusion: the roles of PI3-kinase, Akt, and endothelial nitric oxide synthase phosphorylation. Circulation. 2002 Mar 26; 105(12):1497-502.
    View in: PubMed
  45. Gao F, Yue TL, Shi DW, Christopher TA, Lopez BL, Ohlstein EH, Barone FC, Ma XL. p38 MAPK inhibition reduces myocardial reperfusion injury via inhibition of endothelial adhesion molecule expression and blockade of PMN accumulation. Cardiovasc Res. 2002 Feb 1; 53(2):414-22.
    View in: PubMed
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