Ryan Mark Zurakowski

TitleAssistant Professor
InstitutionUniversity of Delaware
DepartmentElectrical and Computer Engineering
Address127 The Green
Newark DE 19716
Phone302-831-0331
vCardDownload vCard
    Other Positions
    TitleAssistant Professor
    InstitutionUniversity of Delaware
    DepartmentMathematical Sciences

    TitleAssistant Professor
    InstitutionUniversity of Delaware
    DepartmentCenter for Biomedical Engineering Research


    Collapse Research 
    Collapse research activities and funding
    R21AI078842     (ZURAKOWSKI, RYAN M)Jun 5, 2009 - May 31, 2012
    NIH
    Analysis of Differential Resistance Emergence Risk for Differential Treatment App
    Role: Principal Investigator

    R21AI110288     (ZURAKOWSKI, RYAN M)Sep 1, 2014 - Aug 31, 2017
    NIH
    HIV 2-LTR Dynamics and Cryptic Viremia
    Role: Principal Investigator

    R03AI136710     (ZURAKOWSKI, RYAN M)Mar 1, 2018 - Feb 28, 2021
    NIH
    Evidence of cryptic replication in dolutegravir intensification data
    Role: Principal Investigator

    R21AI157889     (GLEGHORN, JASON PAUL)Aug 13, 2021 - Jul 31, 2023
    NIH
    Cell-Mediated Antiretroviral Drug Transport in the Lymph Node
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Pinzone MR, Weissman S, Pasternak AO, Zurakowski R, Migueles S, O'Doherty U. Naive infection predicts reservoir diversity and is a formidable hurdle to HIV eradication. JCI Insight. 2021 Aug 23; 6(16). PMID: 34228640.
      Citations:    
    2. Venanzi Rullo E, Pinzone MR, Cannon L, Weissman S, Ceccarelli M, Zurakowski R, Nunnari G, O'Doherty U. Persistence of an intact HIV reservoir in phenotypically naive T cells. JCI Insight. 2020 Oct 15; 5(20). PMID: 33055422.
      Citations:    
    3. Shirazi J, Donzanti MJ, Nelson KM, Zurakowski R, Fromen CA, Gleghorn JP. Significant Unresolved Questions and Opportunities for Bioengineering in Understanding and Treating COVID-19 Disease Progression. Cell Mol Bioeng. 2020 Jul 27; 1-26. PMID: 32837585.
      Citations:    
    4. Jagarapu A, Piovoso MJ, Zurakowski R. An Integrated Spatial Dynamics-Pharmacokinetic Model Explaining Poor Penetration of Anti-retroviral Drugs in Lymph Nodes. Front Bioeng Biotechnol. 2020; 8:667. PMID: 32676500.
      Citations:    
    5. Jagarapu A, Piovoso MJ, Zurakowski R. Optimal control modulation of HIV reservoir formation rate by antigen infusion. Proc IEEE Conf Decis Control. 2019 Dec; 2019:5662-5667. PMID: 32874015.
      Citations:    
    6. Pinzone MR, Bertuccio MP, VanBelzen DJ, Zurakowski R, O'Doherty U. Next Generation Sequencing in a direct model of HIV infection reveals important parallels and differences to in vivo reservoir dynamics. J Virol. 2020 Feb 12. PMID: 32051279.
      Citations:    
    7. Jagarapu A, Mann R, Piovoso MJ, Zurakowski R. Positive feedback through inflammation creates bistable behavior in HIV tissue sanctuaries. Proc Am Control Conf. 2019 Jul; 2019:3456-3461. PMID: 32148339.
      Citations:    
    8. Cannon L, Vargas-Garcia CA, Jagarapu A, Piovoso MJ, Zurakowski R. HIV 2-LTR experiment design optimization. PLoS One. 2018; 13(11):e0206700. PMID: 30408070.
      Citations:    
    9. Vargas-Garcia C, Zurakowski R, Singh A. Synaptic transmission may provide an evolutionary benefit to HIV through modulation of latency. J Theor Biol. 2018 Oct 14; 455:261-268. PMID: 30048721.
      Citations:    
    10. Martinez-Picado J, Zurakowski R, Buzón MJ, Stevenson M. Episomal HIV-1 DNA and its relationship to other markers of HIV-1 persistence. Retrovirology. 2018 Jan 30; 15(1):15. PMID: 29378611.
      Citations:    
    11. Cannon L, Jagarapu A, Vargas-Garcia CA, Piovoso MJ, Zurakowski R. Implications of Measurement Assay Type in Design of HIV Experiments. Proc IEEE Conf Decis Control. 2017 Dec; 2017:4106-4111. PMID: 29445252.
      Citations:    
    12. Jagarapu A, Cannon L, Zurakowski R. Experiment Design for Early Molecular Events in HIV Infection. Proc Am Control Conf. 2017 May; 2017:122-127. PMID: 29332992.
      Citations:    
    13. Abraham G, Jagarapu A, Cannon L, Zurakowski R. Order preservation of expected information content using Unscented Transform approximation of multivariate prior distributions in HIV 2-LTR experiment design. Proc IEEE Conf Decis Control. 2016 Dec; 2016:5597-5602. PMID: 29332990.
      Citations:    
    14. Cardozo EF, Piovoso MJ, Zurakowski R. Increased inflammation in sanctuary sites may explain viral blips in HIV infection. IET Syst Biol. 2016 Aug; 10(4):153-66. PMID: 27444025.
      Citations:    
    15. Cannon L, Garcia CAV, Piovoso MJ, Zurakowski R. Prospective HIV Clinical Trial Comparison by Expected Kullback-Leibler Divergence. Proc Am Control Conf. 2016 Jul; 2016:1295-1300. PMID: 29332991.
      Citations:    
    16. Zurakowski R. Using the Tools we Have: Low-efficacy Vaccines and HIV. EBioMedicine. 2015 Dec; 2(12):1867-8. PMID: 26844264.
      Citations:    
    17. Buzon MJ, Martin-Gayo E, Pereyra F, Ouyang Z, Sun H, Li JZ, Piovoso M, Shaw A, Dalmau J, Zangger N, Martinez-Picado J, Zurakowski R, Yu XG, Telenti A, Walker BD, Rosenberg ES, Lichterfeld M. Long-Term Antiretroviral Treatment Initiated at Primary HIV-1 Infection Affects the Size, Composition, and Decay Kinetics of the Reservoir of HIV-1-Infected CD4 T Cells. J Virol. 2014 Sep 1; 88(17):10056-65. PMID: 24965451.
      Citations:    
    18. Buzon MJ, Sun H, Li C, Shaw A, Seiss K, Ouyang Z, Martin-Gayo E, Leng J, Henrich TJ, Li JZ, Pereyra F, Zurakowski R, Walker BD, Rosenberg ES, Yu XG, Lichterfeld M. HIV-1 persistence in CD4(+) T cells with stem cell-like properties. Nat Med. 2014 Feb; 20(2):139-42. PMID: 24412925.
      Citations:    
    19. Cardozo EF, Luo R, Piovoso MJ, Zurakowski R. Spatial modeling of HIV cryptic viremia and 2-LTR formation during raltegravir intensification. J Theor Biol. 2014 Mar 21; 345:61-9. PMID: 24378646.
      Citations:    
    20. Luo R, Cardozo EF, Piovoso MJ, Wu H, Buzon MJ, Martinez-Picado J, Zurakowski R. Modelling HIV-1 2-LTR dynamics following raltegravir intensification. J R Soc Interface. 2013; 10(84):20130186. PMID: 23658114.
      Citations:    
    21. Luo R, Piovoso MJ, Zurakowski R. Modeling uncertainty in single-copy assays for HIV. J Clin Microbiol. 2012 Oct; 50(10):3381-2. PMID: 22837324.
      Citations:    
    22. Luo R, Piovoso MJ, Martinez-Picado J, Zurakowski R. HIV model parameter estimates from interruption trial data including drug efficacy and reservoir dynamics. PLoS One. 2012; 7(7):e40198. PMID: 22815727.
      Citations:    
    23. Cardozo EF, Zurakowski R. Robust closed-loop minimal sampling method for HIV therapy switching strategies. IEEE Trans Biomed Eng. 2012 Aug; 59(8):2227-34. PMID: 22652153.
      Citations:    
    24. Cortes LM, Zurakowski R. Resistance evolution in HIV - modeling when to intervene. Proc Am Control Conf. 2012; 2012:4053-4058. PMID: 25264400.
      Citations:    
    25. Luo R, Piovoso MJ, Martinez-Picado J, Zurakowski R. Optimal antiviral switching to minimize resistance risk in HIV therapy. PLoS One. 2011; 6(11):e27047. PMID: 22073250.
      Citations:    
    26. Zurakowski R. Nonlinear observer output-feedback MPC treatment scheduling for HIV. Biomed Eng Online. 2011; 10:40. PMID: 21619634.
      Citations:    
    27. Luo R, Cannon L, Hernandez J, Piovoso MJ, Zurakowski R. Controlling the Evolution of Resistance. J Process Control. 2011 Mar 1; 21(3):367-378. PMID: 21516198.
      Citations:    
    28. Cardozo EF, Zurakowski R. Measurement error robustness of a closed-loop minimal sampling method for HIV therapy switching. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:116-9. PMID: 22254264.
      Citations:    
    29. Luo R, Piovoso MJ, Zurakowski R. Quantitative analysis of viral persistence and transient viral load rebound from HIV clinical data. Conf Proc IEEE Eng Med Biol Soc. 2011; 2011:3585-8. PMID: 22255114.
      Citations:    
    30. Zurakowski R, Churgin M, Perez C, Rodriguez M. Approximate-model closed-loop minimal sampling method for HIV viral-load minima detection. Proc Am Control Conf. 2011; 5418-5419. PMID: 23001383.
      Citations:    
    31. Rosero-Garcia EE, Zurakowski R. Closed-loop minimal sampling method for determining viral-load minima during switching. Proc Am Control Conf. 2010 Jul 29; 2010:460-461. PMID: 23087541.
      Citations:    
    32. Luo R, Piovoso MJ, Zurakowski R. Modeling-error robustness of a viral-load preconditioning strategy for HIV treatment switching. Proc Am Control Conf. 2010; 2010:5155-5160. PMID: 24954972.
      Citations:    
    33. Zurakowski R, Wodarz D. Model-driven approaches for in vitro combination therapy using ONYX-015 replicating oncolytic adenovirus. J Theor Biol. 2007 Mar 7; 245(1):1-8. PMID: 17095020.
      Citations:    
    34. Zurakowski R, Teel AR. A model predictive control based scheduling method for HIV therapy. J Theor Biol. 2006 Jan 21; 238(2):368-82. PMID: 15993900.
      Citations:    
    Zurakowski's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (40)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _
    Physical Neighbors
    _