David Whellan

TitleAssoc Professor
InstitutionThomas Jefferson University
DepartmentCardiology
Address1015 Chestnut Street
Philadelphia PA 19107
Phone215-955-2007
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    U10HL110297     (WHELLAN, DAVID J)Jan 1, 2012 - Dec 31, 2018
    NIH/NHLBI
    The Jefferson Regional Clinical Center for Heart Failure Network
    Role: Principal Investigator

    R34MH097039     (WHELLAN, DAVID J)Aug 1, 2013 - Jul 31, 2016
    NIH/NIMH
    2/3-Multi-Site - Omega-3 for Co-Morbid Depression &HF Treatment (OCEAN)
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Brooksbank JA, Greene SJ, Harris HM, Stebbins A, Fiuzat M, Whellan DJ, Alhanti B, Kraus WE, Piña IL, O'Connor CM, Mentz RJ. Beta-blocker and ACE-inhibitor dosing as a function of body surface area: From the HF-ACTION trial. Am Heart J. 2020 Nov 24; 233:1-4. PMID: 33245905.
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    2. Psotka MA, Abraham WT, Fiuzat M, Filippatos G, Lindenfeld J, Ahmad T, Bhatt AS, Carson PE, Cleland JGF, Felker GM, Januzzi JL, Kitzman DW, Leifer ES, Lewis EF, McMurray JJV, Mentz RJ, Solomon SD, Stockbridge N, Teerlink JR, Vaduganathan M, Vardeny O, Whellan DJ, Wittes J, Anker SD, O'Connor CM. Conduct of Clinical Trials in the Era of COVID-19: JACC Scientific Expert Panel. J Am Coll Cardiol. 2020 11 17; 76(20):2368-2378. PMID: 33183511.
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    3. Pastva AM, Hugenschmidt CE, Kitzman DW, Nelson MB, Brenes GA, Reeves GR, Mentz RJ, Whellan DJ, Chen H, Duncan PW. Cognition, Physical Function, and Quality of Life in Older Patients With Acute Decompensated Heart Failure. J Card Fail. 2020 Sep 18. PMID: 32956816.
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    4. Challapalli J, Maynes EJ, O'Malley TJ, Cross DE, Weber MP, Choi JH, Aggarwal R, Boyle AJ, Whellan DJ, Entwistle JW, Massey HT, Morris RJ, Tchantchaleishvili V. Sleeve Gastrectomy in Patients with Continuous-Flow Left Ventricular Assist Devices: a Systematic Review and Meta-Analysis. Obes Surg. 2020 Jul 11. PMID: 32654017.
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    5. Kokkinos P, Kaminsky LA, Arena R, Zhang J, Franklin B, Kraus W, Triantafyllidi H, Benas D, Whellan DJ, Myers J. New Equations for Predicting Maximum Oxygen Uptake in Patients With Heart Failure. Am J Cardiol. 2020 08 01; 128:7-11. PMID: 32650927.
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    6. Fiuzat M, Ezekowitz J, Alemayehu W, Westerhout CM, Sbolli M, Cani D, Whellan DJ, Ahmad T, Adams K, Piña IL, Patel CB, Anstrom KJ, Cooper LS, Mark D, Leifer ES, Felker GM, Januzzi JL, O'Connor CM. Assessment of Limitations to Optimization of Guideline-Directed Medical Therapy in Heart Failure From the GUIDE-IT Trial: A Secondary Analysis of a Randomized Clinical Trial. JAMA Cardiol. 2020 Apr 22. PMID: 32319999.
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    7. Teng TK, Cooper L, Tay WT, Luo N, Sharma A, Whellan D, Anand I, Pina IL, Tromp J, Richards AM, Kraus WE, Connor CMO, Mentz RJ, Lam CSP. Association between body surface area and prescribed doses of guideline-directed medications among international patients with heart failure and reduced ejection fraction. Eur J Heart Fail. 2019 Dec 18. PMID: 31849161.
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    8. Regan JA, Kitzman DW, Leifer ES, Kraus WE, Fleg JL, Forman DE, Whellan DJ, Wojdyla D, Parikh K, O'Connor CM, Mentz RJ. Impact of Age on Comorbidities and Outcomes in Heart Failure With Reduced Ejection Fraction. JACC Heart Fail. 2019 Dec; 7(12):1056-1065. PMID: 31779928.
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    9. Pandey A, Kitzman D, Whellan DJ, Duncan PW, Mentz RJ, Pastva AM, Nelson MB, Upadhya B, Chen H, Reeves GR. Frailty Among Older Decompensated Heart Failure Patients: Prevalence, Association With Patient-Centered Outcomes, and Efficient Detection Methods. JACC Heart Fail. 2019 Dec; 7(12):1079-1088. PMID: 31779931.
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    10. Whellan DJ. Answering the Clinical Research Challenge in a Growing Health System. Ann Intern Med. 2019 Sep 10. PMID: 31499526.
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    11. Januzzi JL, Ahmad T, Mulder H, Coles A, Anstrom KJ, Adams KF, Ezekowitz JA, Fiuzat M, Houston-Miller N, Mark DB, Piña IL, Passmore G, Whellan DJ, Cooper LS, Leifer ES, Desvigne-Nickens P, Felker GM, O'Connor CM. Natriuretic Peptide Response and Outcomes in Chronic Heart Failure With Reduced Ejection Fraction. J Am Coll Cardiol. 2019 Sep 03; 74(9):1205-1217. PMID: 31466618.
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    12. Reeves GR, Whellan DJ. Getting Paid to Participate: Financial Incentives to Improve Adherence to Cardiac Rehabilitation. JACC Heart Fail. 2019 Jul; 7(7):547-549. PMID: 31078471.
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    13. Taylor RS, Walker S, Smart NA, Piepoli MF, Warren FC, Ciani O, Whellan D, O'Connor C, Keteyian SJ, Coats A, Davos CH, Dalal HM, Dracup K, Evangelista LS, Jolly K, Myers J, Nilsson BB, Passino C, Witham MD, Yeh GY. Impact of Exercise Rehabilitation on Exercise Capacity and Quality-of-Life in Heart Failure: Individual Participant Meta-Analysis. J Am Coll Cardiol. 2019 Apr 02; 73(12):1430-1443. PMID: 30922474.
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    14. O'Connor C, Fiuzat M, Mulder H, Coles A, Ahmad T, Ezekowitz JA, Adams KF, Piña IL, Anstrom KJ, Cooper LS, Mark DB, Whellan DJ, Januzzi JL, Leifer ES, Felker GM. Clinical factors related to morbidity and mortality in high-risk heart failure patients: the GUIDE-IT predictive model and risk score. Eur J Heart Fail. 2019 Mar 27. PMID: 30919549.
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    15. Mark DB, Cowper PA, Anstrom KJ, Sheng S, Daniels MR, Knight JD, Baloch KN, Davidson-Ray L, Fiuzat M, Januzzi JL, Whellan DJ, Piña IL, Ezekowitz JA, Adams KF, Cooper LS, O'Connor CM, Felker GM. Economic and Quality-of-Life Outcomes of Natriuretic Peptide-Guided Therapy for Heart Failure. J Am Coll Cardiol. 2018 Nov 27; 72(21):2551-2562. PMID: 30466512.
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    16. Borlaug BA, Anstrom KJ, Lewis GD, Shah SJ, Levine JA, Koepp GA, Givertz MM, Felker GM, LeWinter MM, Mann DL, Margulies KB, Smith AL, Tang WHW, Whellan DJ, Chen HH, Davila-Roman VG, McNulty S, Desvigne-Nickens P, Hernandez AF, Braunwald E, Redfield MM. Effect of Inorganic Nitrite vs Placebo on Exercise Capacity Among Patients With Heart Failure With Preserved Ejection Fraction: The INDIE-HFpEF Randomized Clinical Trial. JAMA. 2018 11 06; 320(17):1764-1773. PMID: 30398602.
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    17. Warraich HJ, Kitzman DW, Whellan DJ, Duncan PW, Mentz RJ, Pastva AM, Nelson MB, Upadhya B, Reeves GR. Physical Function, Frailty, Cognition, Depression, and Quality of Life in Hospitalized Adults =60 Years With Acute Decompensated Heart Failure With Preserved Versus Reduced Ejection Fraction. Circ Heart Fail. 2018 Nov; 11(11):e005254. PMID: 30571197.
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    18. Dickinson MG, Allen LA, Albert NA, Salvo TD, Ewald GA, Vest AR, Whellan DJ, Zile MR, Givertz MM. Remote Monitoring of Patients with Heart Failure: A White Paper from the Heart Failure Society of America Scientific Statements Committee. J Card Fail. 2018 Oct 08. PMID: 30308242.
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    19. Taylor RS, Walker S, Smart NA, Piepoli MF, Warren FC, Ciani O, O'Connor C, Whellan D, Keteyian SJ, Coats A, Davos CH, Dalal HM, Dracup K, Evangelista L, Jolly K, Myers J, McKelvie RS, Nilsson BB, Passino C, Witham MD, Yeh GY, Zwisler AO. Impact of exercise-based cardiac rehabilitation in patients with heart failure (ExTraMATCH II) on mortality and hospitalisation: an individual patient data meta-analysis of randomised trials. Eur J Heart Fail. 2018 Sep 26. PMID: 30255969.
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    20. Luo N, O'Connor CM, Cooper LB, Sun JL, Coles A, Reed SD, Whellan DJ, Piña IL, Kraus WE, Mentz RJ. Relationship between changing patient-reported outcomes and subsequent clinical events in patients with chronic heart failure: insights from HF-ACTION. Eur J Heart Fail. 2018 Aug 31. PMID: 30168635.
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    21. Jiang W, Whellan DJ, Adams KF, Babyak MA, Boyle SH, Wilson JL, Patel CB, Rogers JG, Harris WS, O'Connor CM. Long-Chain Omega-3 Fatty Acid Supplements in Depressed Heart Failure Patients: Results of the OCEAN Trial. JACC Heart Fail. 2018 Oct; 6(10):833-843. PMID: 30098961.
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    22. Parikh KS, Fiuzat M, Davis G, Neely M, Blain-Nelson P, Whellan DJ, Abraham WT, Adams KF, Felker GM, Liggett SB, O'Connor CM, Bristow MR. Dose Response of ß-Blockers in Adrenergic Receptor Polymorphism Genotypes. Circ Genom Precis Med. 2018 Aug; 11(8):e002210. PMID: 30354340.
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    23. Fudim M, O'Connor CM, Mulder H, Coles A, Bhatt AS, Ambrosy AP, Kraus WE, Piña IL, Whellan DJ, Mentz RJ. Loop diuretic adjustments in patients with chronic heart failure: Insights from HF-ACTION. Am Heart J. 2018 Jul 29. PMID: 30158057.
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    24. Piccini JP, Pokorney SD, Anstrom KJ, Oldenburg O, Punjabi NM, Fiuzat M, Tasissa G, Whellan DJ, Lindenfeld J, Benjafield A, Woehrle H, Blase A, O'Connor CM. Adaptive servo-ventilation reduces atrial fibrillation burden in patients with heart failure and sleep apnea. Heart Rhythm. 2018 Jul 27. PMID: 30059750.
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    25. Whellan DJ. What Is Your Quest? JACC Heart Fail. 2018 Jul; 6(7):605-606. PMID: 29957193.
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    26. Warraich HJ, O'Connor C, Wu A, Coles A, Kraus WE, Piña IL, Whellan DJ, Mentz RJ. Differences Between Patients Enrolled Early and Late During Clinical Trial Recruitment: Insights From the HF-ACTION Trial. Circ Cardiovasc Qual Outcomes. 2018 Jul; 11(7):e004643. PMID: 29980656.
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    27. Ambrosy AP, Mulder H, Coles A, Krauss WE, Lam CSP, McCullough PA, Pina I, Tromp J, Whellan DJ, O'Connor CM, Mentz RJ. Renal Function and Exercise Training in AmbulatoryHeart Failure Patients With a Reduced Ejection Fraction. Am J Cardiol. 2018 Sep 15; 122(6):999-1007. PMID: 30269900.
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    28. Daubert MA, Whellan DJ, Woehrle H, Tasissa G, Anstrom KJ, Lindenfeld J, Benjafield A, Blase A, Punjabi N, Fiuzat M, Oldenburg O, O'Connor CM. Treatment of sleep-disordered breathing in heart failure impacts cardiac remodeling: Insights from the CAT-HF Trial. Am Heart J. 2018 Jul; 201:40-48. PMID: 29910054.
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    29. Ambrosy AP, Bhatt AS, Stebbins AL, Wruck LM, Fudim M, Greene SJ, Kraus WE, O'Connor CM, Piña IL, Whellan DJ, Mentz RJ. Prevalent digoxin use and subsequent risk of death or hospitalization in ambulatory heart failure patients with a reduced ejection fraction-Findings from the Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION) randomized controlled trial. Am Heart J. 2018 May; 199:97-104. PMID: 29754673.
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    30. O'Connor CM, Psotka MA, Fiuzat M, Lindenfeld J, Abraham WT, Bristow MR, Canos D, Harrington RA, Hillebrenner M, Jessup M, Malik FI, Solomon SD, Stockbridge N, Tcheng JE, Unger EF, Whellan DJ, Zuckerman B, Califf RM. Improving Heart Failure Therapeutics Development in the United States: The Heart Failure Collaboratory. J Am Coll Cardiol. 2018 Jan 30; 71(4):443-453. PMID: 29389362.
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    31. Marbach JA, Johnson D, Kloo J, Vira A, Keith S, Kraft WK, Margules N, Whellan D. The Impact of a Transition of Care Program on Acute Myocardial Infarction Readmission Rates. Am J Med Qual. 2018 Jan 01; 1062860618754702. PMID: 29374965.
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    32. Whellan DJ. Change Is Not Always Good. J Am Coll Cardiol. 2017 Nov 14; 70(20):2501-2503. PMID: 29145949.
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    33. Pastva AM, Duncan PW, Reeves GR, Nelson MB, Whellan DJ, O'Connor CM, Eggebeen JD, Hewston LA, Taylor KM, Mentz RJ, Rosenberg PB, Kitzman DW. Strategies for supporting intervention fidelity in the rehabilitation therapy in older acute heart failure patients (REHAB-HF) trial. Contemp Clin Trials. 2018 Jan; 64:118-127. PMID: 29079391.
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    34. Sharma S, Mather PJ, Chowdhury A, Gupta S, Mukhtar U, Willes L, Whellan DJ, Malhotra A, Quan SF. Sleep Overnight Monitoring for Apnea in Patients Hospitalized with Heart Failure (SOMA-HF Study). J Clin Sleep Med. 2017 Oct 15; 13(10):1185-1190. PMID: 28859720.
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    35. Sharma A, Stevens SR, Lucas J, Fiuzat M, Adams KF, Whellan DJ, Donahue MP, Kitzman DW, Piña IL, Zannad F, Kraus WE, O'Connor CM, Felker GM. Utility of Growth Differentiation Factor-15, A Marker of Oxidative Stress and Inflammation, in Chronic Heart Failure: Insights From the HF-ACTION Study. JACC Heart Fail. 2017 Oct; 5(10):724-734. PMID: 28958347.
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    36. Felker GM, Anstrom KJ, Adams KF, Ezekowitz JA, Fiuzat M, Houston-Miller N, Januzzi JL, Mark DB, Piña IL, Passmore G, Whellan DJ, Yang H, Cooper LS, Leifer ES, Desvigne-Nickens P, O'Connor CM. Effect of Natriuretic Peptide-Guided Therapy on Hospitalization or Cardiovascular Mortality in High-Risk Patients With Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial. JAMA. 2017 08 22; 318(8):713-720. PMID: 28829876.
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    37. Butler J, Anstrom KJ, Felker GM, Givertz MM, Kalogeropoulos AP, Konstam MA, Mann DL, Margulies KB, McNulty SE, Mentz RJ, Redfield MM, Tang WHW, Whellan DJ, Shah M, Desvigne-Nickens P, Hernandez AF, Braunwald E. Efficacy and Safety of Spironolactone in Acute Heart Failure: The ATHENA-HF Randomized Clinical Trial. JAMA Cardiol. 2017 Jul 12. PMID: 28700781.
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    38. Luo N, Teng TK, Tay WT, Anand IS, Kraus WE, Liew HB, Ling LH, O'Connor CM, Piña IL, Richards AM, Shimizu W, Whellan DJ, Yap J, Lam CSP, Mentz RJ. Multinational and multiethnic variations in health-related quality of life in patients with chronic heart failure. Am Heart J. 2017 Sep; 191:75-81. PMID: 28888273.
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    39. Lewis GD, Malhotra R, Hernandez AF, McNulty SE, Smith A, Felker GM, Tang WHW, LaRue SJ, Redfield MM, Semigran MJ, Givertz MM, Van Buren P, Whellan D, Anstrom KJ, Shah MR, Desvigne-Nickens P, Butler J, Braunwald E. Effect of Oral Iron Repletion on Exercise Capacity in Patients With Heart Failure With Reduced Ejection Fraction and Iron Deficiency: The IRONOUT HF Randomized Clinical Trial. JAMA. 2017 May 16; 317(19):1958-1966. PMID: 28510680.
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    40. Luo N, Merrill P, Parikh KS, Whellan DJ, Piña IL, Fiuzat M, Kraus WE, Kitzman DW, Keteyian SJ, O'Connor CM, Mentz RJ. Exercise Training in Patients With Chronic Heart Failure and Atrial Fibrillation. J Am Coll Cardiol. 2017 Apr 04; 69(13):1683-1691. PMID: 28359513.
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    41. O'Connor CM, Whellan DJ, Fiuzat M, Punjabi NM, Tasissa G, Anstrom KJ, Benjafield AV, Woehrle H, Blase AB, Lindenfeld J, Oldenberg O. Cardiovascular Outcomes With Minute Ventilation-Targeted Adaptive Servo-Ventilation Therapy in Heart Failure: The CAT-HF Trial. J Am Coll Cardiol. 2017 Mar 28; 69(12):1577-1587. PMID: 28335841.
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    42. Reeves GR, Whellan DJ, O'Connor CM, Duncan P, Eggebeen JD, Morgan TM, Hewston LA, Pastva A, Patel MJ, Kitzman DW. A Novel Rehabilitation Intervention for Older Patients With Acute Decompensated Heart Failure: The REHAB-HF Pilot Study. JACC Heart Fail. 2017 May; 5(5):359-366. PMID: 28285121.
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    43. Whellan DJ, Lindenfeld J. Easy to Predict, Difficult to Prevent. JACC Heart Fail. 2017 Mar; 5(3):226-228. PMID: 28254129.
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    44. Levy WC, Li Y, Reed SD, Zile MR, Shadman R, Dardas T, Whellan DJ, Schulman KA, Ellis SJ, Neilson M, O'Connor CM. Does the Implantable Cardioverter-Defibrillator Benefit Vary With the Estimated Proportional Risk of Sudden Death in Heart Failure Patients? JACC Clin Electrophysiol. 2017 Mar; 3(3):291-298. PMID: 28553663.
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    45. Ambrosy AP, Cerbin LP, DeVore AD, Greene SJ, Kraus WE, O'Connor CM, Piña IL, Whellan DJ, Wojdyla D, Wu A, Mentz RJ. Aerobic exercise training and general health status in ambulatory heart failure patients with a reduced ejection fraction-Findings from the Heart Failure and A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION)trial. Am Heart J. 2017 Apr; 186:130-138. PMID: 28454828.
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    46. Reeves GR, Whellan DJ, Duncan P, O'Connor CM, Pastva AM, Eggebeen JD, Hewston LA, Morgan TM, Reed SD, Rejeski WJ, Mentz RJ, Rosenberg PB, Kitzman DW. Rehabilitation Therapy in Older Acute Heart Failure Patients (REHAB-HF) trial: Design and rationale. Am Heart J. 2017 Mar; 185:130-139. PMID: 28267466.
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    47. Felker GM, Whellan DJ. Inpatient Management of Heart Failure: Are We Shooting at the Right Target? Ann Intern Med. 2016 Nov 29. PMID: 27894128.
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    48. Verma AK, Schulte PJ, Bittner V, Keteyian SJ, Fleg JL, Piña IL, Swank AM, Fitz-Gerald M, Ellis SJ, Kraus WE, Whellan DJ, O'Connor CM, Mentz RJ. Socioeconomic and partner status in chronic heart failure: Relationship to exercise capacity, quality of life, and clinical outcomes. Am Heart J. 2017 Jan; 183:54-61. PMID: 27979042.
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    49. Bhamidipati D, Goldhammer JE, Sperling MR, Torjman MC, McCarey MM, Whellan DJ. Cognitive Outcomes After Coronary Artery Bypass Grafting. J Cardiothorac Vasc Anesth. 2017 Apr; 31(2):707-718. PMID: 28094177.
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    50. Valentino M, Al Danaf J, Panakos A, Ragupathi L, Duffy D, Whellan D. Impact of the 2013 American College of Cardiology/American Heart Association cholesterol guidelines on the prescription of high-intensity statins in patients hospitalized for acute coronary syndrome or stroke. Am Heart J. 2016 Nov; 181:130-136. PMID: 27823684.
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    51. Margulies KB, Hernandez AF, Redfield MM, Givertz MM, Oliveira GH, Cole R, Mann DL, Whellan DJ, Kiernan MS, Felker GM, McNulty SE, Anstrom KJ, Shah MR, Braunwald E, Cappola TP. Effects of Liraglutide on Clinical Stability Among Patients With Advanced Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial. JAMA. 2016 Aug 2; 316(5):500-8. PMID: 27483064.
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    52. Goldstein JL, Scheiman JM, Fort JG, Whellan DJ. Aspirin Use in Secondary Cardiovascular Protection and the Development of Aspirin-Associated Erosions and Ulcers. J Cardiovasc Pharmacol. 2016 Aug; 68(2):121-6. PMID: 27002280.
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    53. Parikh KS, Coles A, Schulte PJ, Kraus WE, Fleg JL, Keteyian SJ, Piña IL, Fiuzat M, Whellan DJ, O'Connor CM, Mentz RJ. Relation of Angina Pectoris to Outcomes, Quality of Life, and Response to Exercise Training in Patients With Chronic Heart Failure (from HF-ACTION). Am J Cardiol. 2016 Oct 15; 118(8):1211-1216. PMID: 27561194.
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    54. Kelly JP, Dunning A, Schulte PJ, Fiuzat M, Leifer ES, Fleg JL, Cooper LS, Keteyian SJ, Kitzman DW, Pina IL, Kraus WE, Whellan DJ, O'Connor CM, Mentz RJ. Statins and Exercise Training Response in Heart Failure Patients: Insights From HF-ACTION. JACC Heart Fail. 2016 Aug; 4(8):617-24. PMID: 27395348.
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    55. Reeves GR, Whellan DJ, Patel MJ, O'Connor CM, Duncan P, Eggebeen JD, Morgan TM, Hewston LA, Pastva AM, Kitzman DW. Comparison of Frequency of Frailty and Severely Impaired Physical Function in Patients =60 Years Hospitalized With Acute Decompensated Heart Failure Versus Chronic Stable Heart Failure With Reduced and Preserved Left Ventricular Ejection Fraction. Am J Cardiol. 2016 Jun 15; 117(12):1953-8. PMID: 27156830.
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    56. Goldstein JL, Whellan DJ, Scheiman JM, Cryer BL, Eisen GM, Lanas A, Fort JG. Long-Term Safety of a Coordinated Delivery Tablet of Enteric-Coated Aspirin 325 mg and Immediate-Release Omeprazole 40 mg for Secondary Cardiovascular Disease Prevention in Patients at GI Risk. Cardiovasc Ther. 2016 Apr; 34(2):59-66. PMID: 26725920.
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    57. Whellan DJ, McCarey MM, Taylor BS, Rosengart TK, Wallace AS, Shroyer AL, Gammie JS, Peterson ED. Trends in Robotic-Assisted Coronary Artery Bypass Grafts: A Study of The Society of Thoracic Surgeons Adult Cardiac Surgery Database, 2006 to 2012. Ann Thorac Surg. 2016 Jul; 102(1):140-6. PMID: 27016838.
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    58. Whellan DJ, Stebbins A, Hernandez AF, Ezekowitz JA, McMurray JJ, Mather PJ, Hasselblad V, O'Connor CM. Dichotomous Relationship Between Age and 30-Day Death or Rehospitalization in Heart Failure Patients Admitted With Acute Decompensated Heart Failure: Results From the ASCEND-HF Trial. J Card Fail. 2016 Jun; 22(6):409-16. PMID: 26952241.
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    59. Fiuzat M, Oldenberg O, Whellan DJ, Woehrle H, Punjabi NM, Anstrom KJ, Blase AB, Benjafield AV, Lindenfeld J, O'Connor CM. Lessons learned from a clinical trial: Design, rationale, and insights from The Cardiovascular Improvements with Minute Ventilation-targeted Adaptive Sero-Ventilation (ASV) Therapy in Heart Failure (CAT-HF) Study. Contemp Clin Trials. 2016 Mar; 47:158-64. PMID: 26806668.
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    60. Sharma S, Mather P, Gupta A, Reeves G, Rubin S, Bonita R, Chowdhury A, Malloy R, Willes L, Whellan D. Effect of Early Intervention With Positive Airway Pressure Therapy for Sleep Disordered Breathing on Six-Month Readmission Rates in Hospitalized Patients With Heart Failure. Am J Cardiol. 2016 Mar 15; 117(6):940-5. PMID: 26830259.
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    61. Banks AZ, Mentz RJ, Stebbins A, Mikus CR, Schulte PJ, Fleg JL, Cooper LS, Leifer ES, Badenhop DT, Keteyian SJ, Piña IL, Kitzman DW, Fiuzat M, Whellan DJ, Kraus WE, O'Connor CM. Response to Exercise Training and Outcomes in Patients With Heart Failure and Diabetes Mellitus: Insights From the HF-ACTION Trial. J Card Fail. 2016 Jul; 22(7):485-91. PMID: 26687984.
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    62. Cooper LB, Mentz RJ, Sun JL, Schulte PJ, Fleg JL, Cooper LS, Piña IL, Leifer ES, Kraus WE, Whellan DJ, Keteyian SJ, O'Connor CM. Psychosocial Factors, Exercise Adherence, and Outcomes in Heart Failure Patients: Insights From Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION). Circ Heart Fail. 2015 Nov; 8(6):1044-51. PMID: 26578668.
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    63. Fiuzat M, Wojdyla D, Pina I, Adams K, Whellan D, O'Connor CM. Heart Rate or Beta-Blocker Dose? Association With Outcomes in Ambulatory Heart Failure Patients With Systolic Dysfunction: Results From the HF-ACTION Trial. JACC Heart Fail. 2016 Feb; 4(2):109-15. PMID: 26519996.
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    64. Sharma S, Mather P, Efird JT, Kahn D, Cheema M, Rubin S, Reeves G, Bonita R, Malloy R, Whellan DJ. Photoplethysmographic Signal to Screen Sleep-Disordered Breathing in Hospitalized Heart Failure Patients: Feasibility of a Prospective Clinical Pathway. JACC Heart Fail. 2015 Sep; 3(9):725-31. PMID: 26362449.
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    65. Reed SD, Neilson MP, Gardner M, Li Y, Briggs AH, Polsky DE, Graham FL, Bowers MT, Paul SC, Granger BB, Schulman KA, Whellan DJ, Riegel B, Levy WC. Tools for Economic Analysis of Patient Management Interventions in Heart Failure Cost-Effectiveness Model: A Web-based program designed to evaluate the cost-effectiveness of disease management programs in heart failure. Am Heart J. 2015 Nov; 170(5):951-60. PMID: 26542504.
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    66. Bellam N, Kelkar AA, Whellan DJ. Team-Based Care for Managing Cardiac Comorbidities in Heart Failure. Heart Fail Clin. 2015 Jul; 11(3):407-17. PMID: 26142638.
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    67. Colvin M, Sweitzer NK, Albert NM, Krishnamani R, Rich MW, Stough WG, Walsh MN, Westlake Canary CA, Allen LA, Bonnell MR, Carson PE, Chan MC, Dickinson MG, Dries DL, Ewald GA, Fang JC, Hernandez AF, Hershberger RE, Katz SD, Moore S, Rodgers JE, Rogers JG, Vest AR, Whellan DJ, Givertz MM. Heart Failure in Non-Caucasians, Women, and Older Adults: A White Paper on Special Populations From the Heart Failure Society of America Guideline Committee. J Card Fail. 2015 Aug; 21(8):674-93. PMID: 26051012.
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    68. Ahmad T, O'Brien EC, Schulte PJ, Stevens SR, Fiuzat M, Kitzman DW, Adams KF, Kraus WE, Piña IL, Donahue MP, Zannad F, Whellan DJ, O'Connor CM, Felker GM. Evaluation of the Incremental Prognostic Utility of Increasingly Complex Testing in Chronic Heart Failure. Circ Heart Fail. 2015 Jul; 8(4):709-16. PMID: 26034004.
      Citations:    
    69. Fang JC, Ewald GA, Allen LA, Butler J, Westlake Canary CA, Colvin-Adams M, Dickinson MG, Levy P, Stough WG, Sweitzer NK, Teerlink JR, Whellan DJ, Albert NM, Krishnamani R, Rich MW, Walsh MN, Bonnell MR, Carson PE, Chan MC, Dries DL, Hernandez AF, Hershberger RE, Katz SD, Moore S, Rodgers JE, Rogers JG, Vest AR, Givertz MM. Advanced (stage d) heart failure: a statement from the heart failure society of america guidelines committee. J Card Fail. 2015 Jun; 21(6):519-34. PMID: 25953697.
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    70. Mentz RJ, Babyak MA, Bittner V, Fleg JL, Keteyian SJ, Swank AM, Piña IL, Kraus WE, Whellan DJ, O'Connor CM, Blumenthal JA. Prognostic significance of depression in blacks with heart failure: insights from heart failure: a controlled trial investigating outcomes of exercise training. Circ Heart Fail. 2015 May; 8(3):497-503. PMID: 25901047.
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    71. Dardas T, Li Y, Reed SD, O'Connor CM, Whellan DJ, Ellis SJ, Schulman KA, Kraus WE, Forman DE, Levy WC. Incremental and independent value of cardiopulmonary exercise test measures and the Seattle Heart Failure Model for prediction of risk in patients with heart failure. J Heart Lung Transplant. 2015 Aug; 34(8):1017-23. PMID: 25940075.
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    72. Whellan DJ, Kraus WE, Kitzman DW, Rooney B, Keteyian SJ, Piña IL, Ellis SJ, Ghali JK, Lee KL, Cooper LS, O'Connor CM. Authorship in a multicenter clinical trial: The Heart Failure-A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION) Authorship and Publication (HAP) Scoring System Results. Am Heart J. 2015 Apr; 169(4):457-463.e6. PMID: 25819851.
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    73. Fleg JL, Cooper LS, Borlaug BA, Haykowsky MJ, Kraus WE, Levine BD, Pfeffer MA, Piña IL, Poole DC, Reeves GR, Whellan DJ, Kitzman DW. Exercise training as therapy for heart failure: current status and future directions. Circ Heart Fail. 2015 Jan; 8(1):209-20. PMID: 25605639.
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    74. Sharma V, Rathman LD, Small RS, Whellan DJ, Koehler J, Warman E, Abraham WT. Stratifying patients at the risk of heart failure hospitalization using existing device diagnostic thresholds. Heart Lung. 2015 Mar-Apr; 44(2):129-36. PMID: 25543319.
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    75. Reeves GR, Whellan DJ. Cardiac Rehabilitation in Left Ventricular Assist Device Recipients: Can it Bolster the Benefits of Restored Flow? JACC Heart Fail. 2014 Dec; 2(6):660-2. PMID: 25447349.
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    76. Ahmad T, Pencina MJ, Schulte PJ, O'Brien E, Whellan DJ, Piña IL, Kitzman DW, Lee KL, O'Connor CM, Felker GM. Clinical Implications of Chronic Heart Failure Phenotypes Defined by Cluster Analysis. J Am Coll Cardiol. 2014 Oct 28; 64(17):1765-74. PMID: 25443696.
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    77. Zeitler EP, Piccini JP, Hellkamp AS, Whellan DJ, Jackson KP, Ellis SJ, Kraus WE, Keteyian SJ, Kitzman DW, Ewald GA, Fleg JL, Piña IL, O'Connor CM. Exercise Training and Pacing Status in Patients With Heart Failure: Results From HF-ACTION. J Card Fail. 2015 Jan; 21(1):60-7. PMID: 25463413.
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    78. Duffy D, Rooney B, Adams S, Whellan DJ. PA32540 for the secondary prevention of cardiovascular disease in patients at risk for aspirin-associated gastric ulcers. Expert Rev Cardiovasc Ther. 2014 Nov; 12(11):1251-60. PMID: 25300316.
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    79. Felker GM, Ahmad T, Anstrom KJ, Adams KF, Cooper LS, Ezekowitz JA, Fiuzat M, Houston-Miller N, Januzzi JL, Leifer ES, Mark DB, Desvigne-Nickens P, Paynter G, Piña IL, Whellan DJ, O'Connor CM. Rationale and Design of the GUIDE-IT Study: Guiding Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure. JACC Heart Fail. 2014 Oct; 2(5):457-65. PMID: 25194287.
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    80. Jones LW, Douglas PS, Khouri MG, Mackey JR, Wojdyla D, Kraus WE, Whellan DJ, O'Connor CM. Safety and Efficacy of Aerobic Training in Patients With Cancer Who Have Heart Failure: An Analysis of the HF-ACTION Randomized Trial. J Clin Oncol. 2014 Aug 10; 32(23):2496-502. PMID: 25002717.
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    81. Whellan DJ, Goldstein JL, Cryer BL, Eisen GM, Lanas A, Miller AB, Scheiman JM, Fort JG, Zhang Y, O'Connor C. PA32540 (a coordinated-delivery tablet of enteric-coated aspirin 325 mg and immediate-release omeprazole 40 mg) versus enteric-coated aspirin 325 mg alone in subjects at risk for aspirin-associated gastric ulcers: Results of two 6-month, phase 3 studies. Am Heart J. 2014 Oct; 168(4):495-502.e4. PMID: 25262259.
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    82. Li Y, Levy WC, Neilson MP, Ellis SJ, Whellan DJ, Schulman KA, O'Connor CM, Reed SD. Associations Between Seattle Heart Failure Model Scores and Medical Resource Use and Costs: Findings From HF-ACTION. J Card Fail. 2014 Aug; 20(8):541-7. PMID: 24887579.
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    83. Ahmad T, Fiuzat M, Neely B, Neely ML, Pencina MJ, Kraus WE, Zannad F, Whellan DJ, Donahue MP, Piña IL, Adams KF, Kitzman DW, O'Connor CM, Felker GM. Biomarkers of myocardial stress and fibrosis as predictors of mode of death in patients with chronic heart failure. JACC Heart Fail. 2014 Jun; 2(3):260-8. PMID: 24952693.
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    84. Taylor RS, Piepoli MF, Smart N, Coats AJ, Ellis S, Dalal H, O'Connor CM, Warren FC, Whellan D, Ciani O. Exercise training for chronic heart failure (ExTraMATCH II): Protocol for an individual participant data meta-analysis. Int J Cardiol. 2014 Jul 1; 174(3):683-7. PMID: 24804902.
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    85. Small RS, Whellan DJ, Boyle A, Sarkar S, Koehler J, Warman EN, Abraham WT. Implantable device diagnostics on day of discharge identify heart failure patients at increased risk for early readmission for heart failure. Eur J Heart Fail. 2014 Apr; 16(4):419-25. PMID: 24464745.
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    86. Whellan DJ, Goodlin SJ, Dickinson MG, Heidenreich PA, Jaenicke C, Stough WG, Rich MW. End-of-Life Care in Patients With Heart Failure. J Card Fail. 2014 Feb; 20(2):121-34. PMID: 24556532.
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    87. Leifer ES, Brawner CA, Fleg JL, Kraus WE, Whellan DJ, Piña IL, Keteyian SJ. Are There Negative Responders to Exercise Training among Heart Failure Patients? Med Sci Sports Exerc. 2014 Feb; 46(2):219-24. PMID: 23860416.
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    88. Duffy D, Kelly E, Trang A, Whellan D, Mills G. Aspirin for cardioprotection and strategies to improve patient adherence. Postgrad Med. 2014 Jan; 126(1):18-28. PMID: 24393748.
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    89. Andrikopoulou E, Abbate K, Whellan DJ. Conceptual model for heart failure disease management. Can J Cardiol. 2014 Mar; 30(3):304-11. PMID: 24565255.
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    90. Fiuzat M, Schulte PJ, Felker M, Ahmad T, Neely M, Adams KF, Donahue MP, Kraus WE, Piña IL, Whellan DJ, O'Connor CM. Relationship Between Galectin-3 Levels and Mineralocorticoid Receptor Antagonist Use in Heart Failure: Analysis From HF-ACTION. J Card Fail. 2014 Jan; 20(1):38-44. PMID: 24304938.
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    91. Whellan DJ, Tricoci P, Chen E, Huang Z, Leibowitz D, Vranckx P, Marhefka GD, Held C, Nicolau JC, Storey RF, Ruzyllo W, Huber K, Sinnaeve P, Weiss AT, Dery JP, Moliterno DJ, Van de Werf F, Aylward PE, White HD, Armstrong PW, Wallentin L, Strony J, Harrington RA, Mahaffey KW. Vorapaxar in Acute Coronary Syndrome Patients Undergoing Coronary Artery Bypass Graft Surgery: Subgroup Analysis From the TRACER Trial (Thrombin Receptor Antagonist for Clinical Event Reduction in Acute Coronary Syndrome). J Am Coll Cardiol. 2014 Mar 25; 63(11):1048-57. PMID: 24211500.
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    92. Ahmad T, Fiuzat M, Mark DB, Neely B, Neely M, Kraus WE, Kitzman DW, Whellan DJ, Donahue M, Zannad F, Piña IL, Adams K, O'Connor CM, Felker GM. The effects of exercise on cardiovascular biomarkers in patients with chronic heart failure. Am Heart J. 2014 Feb; 167(2):193-202.e1. PMID: 24439980.
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    93. Green CL, Whellan DJ, Lambe L, Bellibas SE, Wijngaard P, Prats J, Krucoff MW. Electrocardiographic Safety of Cangrelor, a New Intravenous Antiplatelet Agent: A Randomized, Double-blind, Placebo- and Moxifloxacin-controlled Thorough QT Study. J Cardiovasc Pharmacol. 2013 Nov; 62(5):466-78. PMID: 23921301.
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    94. Felker GM, Fiuzat M, Thompson V, Shaw LK, Neely ML, Adams KF, Whellan DJ, Donahue MP, Ahmad T, Kitzman DW, Piña IL, Zannad F, Kraus WE, O'Connor CM. Soluble ST2 in Ambulatory Patients With Heart Failure: Association With Functional Capacity and Long-Term Outcomes. Circ Heart Fail. 2013 Nov 1; 6(6):1172-9. PMID: 24103327.
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    95. McCullough PA, Barnard D, Clare R, Ellis SJ, Fleg JL, Fonarow GC, Franklin BA, Kilpatrick RD, Kitzman DW, O'Connor CM, Piña IL, Thadani U, Thohan V, Whellan DJ. Anemia and associated clinical outcomes in patients with heart failure due to reduced left ventricular systolic function. Clin Cardiol. 2013 Oct; 36(10):611-20. PMID: 23929781.
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    96. Mentz RJ, Bittner V, Schulte PJ, Fleg JL, Piña IL, Keteyian SJ, Moe G, Nigam A, Swank AM, Onwuanyi AE, Fitz-Gerald M, Kao A, Ellis SJ, Kraus WE, Whellan DJ, O'Connor CM. Race, exercise training, and outcomes in chronic heart failure: Findings from Heart Failure - A Controlled Trial Investigating Outcomes in Exercise TraiNing (HF-ACTION). Am Heart J. 2013 Sep; 166(3):488-495.e1. PMID: 24016498.
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    97. Piña IL, Lin L, Weinfurt KP, Isitt JJ, Whellan DJ, Schulman KA, Flynn KE. Hemoglobin, exercise training, and health status in patients with chronic heart failure (from the HF-ACTION randomized controlled trial). Am J Cardiol. 2013 Oct 1; 112(7):971-6. PMID: 23809621.
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    98. Eapen ZJ, Reed SD, Li Y, Kociol RD, Armstrong PW, Starling RC, McMurray JJ, Massie BM, Swedberg K, Ezekowitz JA, Fonarow GC, Teerlink JR, Metra M, Whellan DJ, O'Connor CM, Califf RM, Hernandez AF. Do Countries or Hospitals With Longer Hospital Stays for Acute Heart Failure Have Lower Readmission Rates?: Findings From ASCEND-HF. Circ Heart Fail. 2013 Jul 1; 6(4):727-32. PMID: 23770519.
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    99. Li Y, Neilson MP, Whellan DJ, Schulman KA, Levy WC, Reed SD. Associations Between Seattle Heart Failure Model Scores and Health Utilities: Findings From HF-ACTION. J Card Fail. 2013 May; 19(5):311-6. PMID: 23663813.
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    100. Hudson L, Morales A, Mauro AC, Whellan D, Adams KF, O'Connor CM, Hershberger RE. Family History of Dilated Cardiomyopathy among Patients with Heart Failure from the HF-ACTION Genetic Ancillary Study. Clin Transl Sci. 2013 Jun; 6(3):179-83. PMID: 23751021.
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    101. Piccini JP, Hellkamp AS, Whellan DJ, Ellis SJ, Keteyian SJ, Kraus WE, Hernandez AF, Daubert JP, Piña lL, O'Connor CM. Exercise training and implantable cardioverter-defibrillator shocks in patients with heart failure: results from HF-ACTION (Heart Failure and A Controlled Trial Investigating Outcomes of Exercise TraiNing). JACC Heart Fail. 2013 Apr; 1(2):142-8. PMID: 23936756.
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    102. Cowie MR, Sarkar S, Koehler J, Whellan DJ, Crossley GH, Tang WH, Abraham WT, Sharma V, Santini M. Development and validation of an integrated diagnostic algorithm derived from parameters monitored in implantable devices for identifying patients at risk for heart failure hospitalization in an ambulatory setting. Eur Heart J. 2013 Aug; 34(31):2472-80. PMID: 23513212.
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    103. Kim FY, Marhefka G, Ruggiero NJ, Adams S, Whellan DJ. Saphenous vein graft disease: review of pathophysiology, prevention, and treatment. Cardiol Rev. 2013 Mar; 21(2):101-9. PMID: 22968180.
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    104. Mentz RJ, Schulte PJ, Fleg JL, Fiuzat M, Kraus WE, Piña IL, Keteyian SJ, Kitzman DW, Whellan DJ, Ellis SJ, O'Connor CM. Clinical characteristics, response to exercise training, and outcomes in patients with heart failure and chronic obstructive pulmonary disease: Findings from Heart Failure and A Controlled Trial Investigating Outcomes of Exercise TraiNing (HF-ACTION). Am Heart J. 2013 Feb; 165(2):193-9. PMID: 23351822.
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    105. Fiuzat M, Neely ML, Starr AZ, Kraus WE, Felker GM, Donahue M, Adams K, Piña IL, Whellan D, O'Connor CM. Association between adrenergic receptor genotypes and beta-blocker dose in heart failure patients: analysis from the HF-ACTION DNA substudy. Eur J Heart Fail. 2013 Mar; 15(3):258-66. PMID: 23115322.
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    106. Corotto PS, McCarey MM, Adams S, Khazanie P, Whellan DJ. Heart failure patient adherence: epidemiology, cause, and treatment. Heart Fail Clin. 2013 Jan; 9(1):49-58. PMID: 23168317.
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    107. Han SY, Palmeri ST, Broderick SH, Hasselblad V, Rendall D, Stevens S, Tenaglia A, Velazquez E, Whellan D, Wagner G, Heitner JF. Quality of anticoagulation with warfarin in patients with nonvalvular atrial fibrillation in the community setting. J Electrocardiol. 2013 Jan; 46(1):45-50. PMID: 23063241.
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    108. Keteyian SJ, Leifer ES, Houston-Miller N, Kraus WE, Brawner CA, O'Connor CM, Whellan DJ, Cooper LS, Fleg JL, Kitzman DW, Cohen-Solal A, Blumenthal JA, Rendall DS, Piña IL. Relation between volume of exercise and clinical outcomes in patients with heart failure. J Am Coll Cardiol. 2012 Nov 6; 60(19):1899-905. PMID: 23062530.
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    109. Whellan DJ, Sarkar S, Koehler J, Small RS, Boyle A, Warman EN, Abraham WT. Development of a method to risk stratify patients with heart failure for 30-day readmission using implantable device diagnostics. Am J Cardiol. 2013 Jan 1; 111(1):79-84. PMID: 23040596.
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    110. Sarkar S, Koehler J, Crossley GH, Tang WH, Abraham WT, Warman EN, Whellan DJ. Burden of atrial fibrillation and poor rate control detected by continuous monitoring and the risk for heart failure hospitalization. Am Heart J. 2012 Oct; 164(4):616-24. PMID: 23067922.
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    111. Reed SD, Li Y, Ellis SJ, Isitt JJ, Cheng S, Schulman KA, Whellan DJ. Associations between hemoglobin level, resource use, and medical costs in patients with heart failure: findings from HF-ACTION. J Card Fail. 2012 Oct; 18(10):784-91. PMID: 23040114.
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    112. Whellan DJ. Long-term exercise training and adherence: it is not just exercise. J Am Coll Cardiol. 2012 Oct 16; 60(16):1529-30. PMID: 22999726.
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    113. Blumenthal JA, Babyak MA, O'Connor C, Keteyian S, Landzberg J, Howlett J, Kraus W, Gottlieb S, Blackburn G, Swank A, Whellan DJ. Effects of exercise training on depressive symptoms in patients with chronic heart failure: the HF-ACTION randomized trial. JAMA. 2012 Aug 1; 308(5):465-74. PMID: 22851113.
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    114. Reed SD, Li Y, Dunlap ME, Kraus WE, Samsa GP, Schulman KA, Zile MR, Whellan DJ. In-hospital resource use and medical costs in the last year of life by mode of death (from the HF-ACTION randomized controlled trial). Am J Cardiol. 2012 Oct 15; 110(8):1150-5. PMID: 22762718.
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    115. Fiuzat M, Wojdyla D, Kitzman D, Fleg J, Keteyian SJ, Kraus WE, Piña IL, Whellan D, O'Connor CM. Relationship of beta-blocker dose with outcomes in ambulatory heart failure patients with systolic dysfunction: results from the HF-ACTION (Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training) trial. J Am Coll Cardiol. 2012 Jul 17; 60(3):208-15. PMID: 22560018.
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    116. Whellan DJ, Cox M, Hernandez AF, Heidenreich PA, Curtis LH, Peterson ED, Fonarow GC. Utilization of hospice and predicted mortality risk among older patients hospitalized with heart failure: findings from GWTG-HF. J Card Fail. 2012 Jun; 18(6):471-7. PMID: 22633304.
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    117. Whellan DJ, Droogan CJ, Fitzpatrick J, Adams S, McCarey MM, Andrel J, Mather P, Rubin S, Bonita R, Keith S. Change in intrathoracic impedance measures during acute decompensated heart failure admission: results from the Diagnostic Data for Discharge in Heart Failure Patients (3D-HF) Pilot Study. J Card Fail. 2012 Feb; 18(2):107-12. PMID: 22300777.
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    118. Greiner MA, Hammill BG, Fonarow GC, Whellan DJ, Eapen ZJ, Hernandez AF, Curtis LH. Predicting costs among medicare beneficiaries with heart failure. Am J Cardiol. 2012 Mar 1; 109(5):705-11. PMID: 22154317.
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    119. Reed SD, Li Y, Kamble S, Polsky D, Graham FL, Bowers MT, Samsa GP, Paul S, Schulman KA, Whellan DJ, Riegel BJ. Introduction of the Tools for Economic Analysis of Patient Management Interventions in Heart Failure Costing Tool: a user-friendly spreadsheet program to estimate costs of providing patient-centered interventions. Circ Cardiovasc Qual Outcomes. 2012 Jan; 5(1):113-9. PMID: 22147884.
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    120. Whellan DJ, Nigam A, Arnold M, Starr AZ, Hill J, Fletcher G, Ellis SJ, Cooper L, Onwuanyi A, Chandler B, Keteyian SJ, Ewald G, Kao A, Gheorghiade M. Benefit of exercise therapy for systolic heart failure in relation to disease severity and etiology-findings from the Heart Failure and A Controlled Trial Investigating Outcomes of Exercise Training study. Am Heart J. 2011 Dec; 162(6):1003-10. PMID: 22137073.
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    121. O'Connor CM, Whellan DJ, Wojdyla D, Leifer E, Clare RM, Ellis SJ, Fine LJ, Fleg JL, Zannad F, Keteyian SJ, Kitzman DW, Kraus WE, Rendall D, Piña IL, Cooper LS, Fiuzat M, Lee KL. Factors related to morbidity and mortality in patients with chronic heart failure with systolic dysfunction: the HF-ACTION predictive risk score model. Circ Heart Fail. 2012 Jan; 5(1):63-71. PMID: 22114101.
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    122. Tricoci P, Huang Z, Held C, Moliterno DJ, Armstrong PW, Van de Werf F, White HD, Aylward PE, Wallentin L, Chen E, Lokhnygina Y, Pei J, Leonardi S, Rorick TL, Kilian AM, Jennings LH, Ambrosio G, Bode C, Cequier A, Cornel JH, Diaz R, Erkan A, Huber K, Hudson MP, Jiang L, Jukema JW, Lewis BS, Lincoff AM, Montalescot G, Nicolau JC, Ogawa H, Pfisterer M, Prieto JC, Ruzyllo W, Sinnaeve PR, Storey RF, Valgimigli M, Whellan DJ, Widimsky P, Strony J, Harrington RA, Mahaffey KW. Thrombin-receptor antagonist vorapaxar in acute coronary syndromes. N Engl J Med. 2012 Jan 5; 366(1):20-33. PMID: 22077816.
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    123. Felker GM, Fiuzat M, Shaw LK, Clare R, Whellan DJ, Bettari L, Shirolkar SC, Donahue M, Kitzman DW, Zannad F, Piña IL, O'Connor CM. Galectin-3 in ambulatory patients with heart failure: results from the HF-ACTION study. Circ Heart Fail. 2012 Jan; 5(1):72-8. PMID: 22016505.
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    124. O'Connor CM, Mentz RJ, Whellan DJ. Covariate adjustment in heart failure randomized controlled clinical trials: a case analysis of the HF-ACTION trial. Heart Fail Clin. 2011 Oct; 7(4):497-500. PMID: 21925432.
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    125. Bonita RE, Adams S, Whellan DJ. Reporting of clinical trials: publication, authorship, and trial registration. Heart Fail Clin. 2011 Oct; 7(4):561-7. PMID: 21925440.
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    126. Whellan DJ, Adams S, Bowerman L. Review of advanced heart failure device diagnostics examined in clinical trials and the potential benefit from monitoring capabilities. Prog Cardiovasc Dis. 2011 Sep-Oct; 54(2):107-14. PMID: 21875510.
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    127. Whellan DJ, Zhao X, Hernandez AF, Liang L, Peterson ED, Bhatt DL, Heidenreich PA, Schwamm LH, Fonarow GC. Predictors of hospital length of stay in heart failure: findings from Get With the Guidelines. J Card Fail. 2011 Aug; 17(8):649-56. PMID: 21807326.
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    128. Jones WS, Clare R, Ellis SJ, Mills JS, Fischman DL, Kraus WE, Whellan DJ, O'Connor CM, Patel MR. Effect of peripheral arterial disease on functional and clinical outcomes in patients with heart failure (from HF-ACTION). Am J Cardiol. 2011 Aug 1; 108(3):380-4. PMID: 21565325.
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    129. Atchley AE, Iskandrian AE, Bensimhon D, Ellis SJ, Kitzman DW, Shaw LK, Pagnanelli RA, Whellan DJ, Gardin JM, Kao A, Abdul-Nour K, Ewald G, Walsh MN, Kraus WE, O'Connor CM, Borges-Neto S. Relationship of technetium-99m tetrofosmin-gated rest single-photon emission computed tomography myocardial perfusion imaging to death and hospitalization in heart failure patients: results from the nuclear ancillary study of the HF-ACTION trial. Am Heart J. 2011 Jun; 161(6):1038-45. PMID: 21641348.
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    130. Curtis LH, Greiner MA, Shea AM, Whellan DJ, Hammill BG, Schulman KA, Douglas PS. Assessment of left ventricular function in older Medicare beneficiaries with newly diagnosed heart failure. Circ Cardiovasc Qual Outcomes. 2011 Jan 1; 4(1):85-91. PMID: 21098783.
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    131. Reeves GR, Whellan DJ. Recent advances in cardiac rehabilitation. Curr Opin Cardiol. 2010 Nov; 25(6):589-96. PMID: 20881485.
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    132. Unroe KT, Greiner MA, Hernandez AF, Whellan DJ, Kaul P, Schulman KA, Peterson ED, Curtis LH. Resource use in the last 6 months of life among medicare beneficiaries with heart failure, 2000-2007. Arch Intern Med. 2011 Feb 14; 171(3):196-203. PMID: 20937916.
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    133. Feldman AM, Force TL, Whellan DJ, Bray PF, Cheung JY, Koch WJ. Advancing the research mission in an academic department: the creation of a center for translational medicine. Clin Transl Sci. 2010 Aug; 3(4):178-81. PMID: 20718819.
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    134. Reed SD, Whellan DJ, Li Y, Friedman JY, Ellis SJ, Piña IL, Settles SJ, Davidson-Ray L, Johnson JL, Cooper LS, O'Connor CM, Schulman KA. Economic evaluation of the HF-ACTION (Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training) randomized controlled trial: an exercise training study of patients with chronic heart failure. Circ Cardiovasc Qual Outcomes. 2010 Jul; 3(4):374-81. PMID: 20551371.
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    135. Sweeney MO, Ellenbogen KA, Tang AS, Whellan D, Mortensen PT, Giraldi F, Sandler DA, Sherfesee L, Sheldon T. Atrial pacing or ventricular backup-only pacing in implantable cardioverter-defibrillator patients. Heart Rhythm. 2010 Nov; 7(11):1552-60. PMID: 20685401.
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    136. Whellan DJ, Ousdigian KT, Al-Khatib SM, Pu W, Sarkar S, Porter CB, Pavri BB, O'Connor CM. Combined heart failure device diagnostics identify patients at higher risk of subsequent heart failure hospitalizations: results from PARTNERS HF (Program to Access and Review Trending Information and Evaluate Correlation to Symptoms in Patients With Heart Failure) study. J Am Coll Cardiol. 2010 Apr 27; 55(17):1803-10. PMID: 20413029.
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    137. Bonita RE, Raake PW, Otis NJ, Chuprun JK, Spivack T, Dasgupta A, Whellan DJ, Mather PJ, Koch WJ. Dynamic changes in lymphocyte GRK2 levels in cardiac transplant patients: a biomarker for left ventricular function. Clin Transl Sci. 2010 Feb; 3(1):14-8. PMID: 20443948.
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    138. Balog JD, Frisch DR, Whellan DJ, Ho RT. Alternating short and long RP tachycardias: what are the mechanisms? Heart Rhythm. 2010 Dec; 7(12):1907-9. PMID: 20188231.
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    139. Hammill BG, Curtis LH, Schulman KA, Whellan DJ. Relationship between cardiac rehabilitation and long-term risks of death and myocardial infarction among elderly Medicare beneficiaries. Circulation. 2010 Jan 5; 121(1):63-70. PMID: 20026778.
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    140. Barodka V, Silvestry S, Zhao N, Jiao X, Whellan DJ, Diehl J, Sun JZ. Preoperative renin-angiotensin system inhibitors protect renal function in aging patients undergoing cardiac surgery. J Surg Res. 2011 May 15; 167(2):e63-9. PMID: 20189597.
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    141. Kim DH, Daskalakis C, Silvestry SC, Sheth MP, Lee AN, Adams S, Hohmann S, Medvedev S, Whellan DJ. Aspirin and clopidogrel use in the early postoperative period following on-pump and off-pump coronary artery bypass grafting. J Thorac Cardiovasc Surg. 2009 Dec; 138(6):1377-84. PMID: 19931667.
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    142. Whellan DJ, Greiner MA, Schulman KA, Curtis LH. Costs of inpatient care among Medicare beneficiaries with heart failure, 2001 to 2004. Circ Cardiovasc Qual Outcomes. 2010 Jan; 3(1):33-40. PMID: 20123669.
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    143. Chowdhury M, Adams S, Whellan DJ. Sleep-disordered breathing and heart failure: focus on obstructive sleep apnea and treatment with continuous positive airway pressure. J Card Fail. 2010 Feb; 16(2):164-74. PMID: 20142029.
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    144. O'Connor CM, Whellan DJ. Understanding heart failure through the HF-ACTION baseline characteristics. Am Heart J. 2009 Oct; 158(4 Suppl):S1-5. PMID: 19782783.
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    145. Piña IL, Kokkinos P, Kao A, Bittner V, Saval M, Clare B, Goldberg L, Johnson M, Swank A, Ventura H, Moe G, Fitz-Gerald M, Ellis SJ, Vest M, Cooper L, Whellan D. Baseline differences in the HF-ACTION trial by sex. Am Heart J. 2009 Oct; 158(4 Suppl):S16-23. PMID: 19782784.
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    146. Felker GM, Whellan D, Kraus WE, Clare R, Zannad F, Donahue M, Adams K, McKelvie R, Piña IL, O'Connor CM. N-terminal pro-brain natriuretic peptide and exercise capacity in chronic heart failure: data from the Heart Failure and a Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION) study. Am Heart J. 2009 Oct; 158(4 Suppl):S37-44. PMID: 19782787.
      Citations:    
    147. Gardin JM, Leifer ES, Fleg JL, Whellan D, Kokkinos P, Leblanc MH, Wolfel E, Kitzman DW. Relationship of Doppler-Echocardiographic left ventricular diastolic function to exercise performance in systolic heart failure: the HF-ACTION study. Am Heart J. 2009 Oct; 158(4 Suppl):S45-52. PMID: 19782788.
      Citations:    
    148. Atchley AE, Kitzman DW, Whellan DJ, Iskandrian AE, Ellis SJ, Pagnanelli RA, Kao A, Abdul-Nour K, O'Connor CM, Ewald G, Kraus WE, Borges-Neto S. Myocardial perfusion, function, and dyssynchrony in patients with heart failure: baseline results from the single-photon emission computed tomography imaging ancillary study of the Heart Failure and A Controlled Trial Investigating Outcomes of Exercise TraiNing (HF-ACTION) Trial. Am Heart J. 2009 Oct; 158(4 Suppl):S53-63. PMID: 19782789.
      Citations:    
    149. Flynn KE, Lin L, Ellis SJ, Russell SD, Spertus JA, Whellan DJ, Piña IL, Fine LJ, Schulman KA, Weinfurt KP. Outcomes, health policy, and managed care: relationships between patient-reported outcome measures and clinical measures in outpatients with heart failure. Am Heart J. 2009 Oct; 158(4 Suppl):S64-71. PMID: 19782791.
      Citations:    
    150. Kim DH, Sagar UN, Adams S, Whellan DJ. Lifestyle risk factors and utilization of preventive services in disabled elderly adults in the community. J Community Health. 2009 Oct; 34(5):440-8. PMID: 19517224.
      Citations:    
    151. Whellan DJ, Ellis SJ, Kraus WE, Hawthorne K, Piña IL, Keteyian SJ, Kitzman DW, Cooper L, Lee K, O'Connor CM. Method for establishing authorship in a multicenter clinical trial. Ann Intern Med. 2009 Sep 15; 151(6):414-20. PMID: 19755366.
      Citations:    
    152. Riegel B, Moser DK, Anker SD, Appel LJ, Dunbar SB, Grady KL, Gurvitz MZ, Havranek EP, Lee CS, Lindenfeld J, Peterson PN, Pressler SJ, Schocken DD, Whellan DJ. State of the science: promoting self-care in persons with heart failure: a scientific statement from the American Heart Association. Circulation. 2009 Sep 22; 120(12):1141-63. PMID: 19720935.
      Citations:    
    153. Piccini JP, Whellan DJ, Berridge BR, Finkle JK, Pettit SD, Stockbridge N, Valentin JP, Vargas HM, Krucoff MW. Current challenges in the evaluation of cardiac safety during drug development: translational medicine meets the Critical Path Initiative. Am Heart J. 2009 Sep; 158(3):317-26. PMID: 19699852.
      Citations:    
    154. Bain KT, Maxwell TL, Strassels SA, Whellan DJ. Hospice use among patients with heart failure. Am Heart J. 2009 Jul; 158(1):118-25. PMID: 19540401.
      Citations:    
    155. O'Connor CM, Whellan DJ, Lee KL, Keteyian SJ, Cooper LS, Ellis SJ, Leifer ES, Kraus WE, Kitzman DW, Blumenthal JA, Rendall DS, Miller NH, Fleg JL, Schulman KA, McKelvie RS, Zannad F, Piña IL. Efficacy and safety of exercise training in patients with chronic heart failure: HF-ACTION randomized controlled trial. JAMA. 2009 Apr 8; 301(14):1439-50. PMID: 19351941.
      Citations:    
    156. Flynn KE, Piña IL, Whellan DJ, Lin L, Blumenthal JA, Ellis SJ, Fine LJ, Howlett JG, Keteyian SJ, Kitzman DW, Kraus WE, Miller NH, Schulman KA, Spertus JA, O'Connor CM, Weinfurt KP. Effects of exercise training on health status in patients with chronic heart failure: HF-ACTION randomized controlled trial. JAMA. 2009 Apr 8; 301(14):1451-9. PMID: 19351942.
      Citations:    
    157. Kim DH, Daskalakis C, Whellan DJ, Whitman IR, Hohmann S, Medvedev S, Kraft WK. Safety of selective serotonin reuptake inhibitor in adults undergoing coronary artery bypass grafting. Am J Cardiol. 2009 May 15; 103(10):1391-5. PMID: 19427434.
      Citations:    
    158. Curtis LH, Greiner MA, Hammill BG, Kramer JM, Whellan DJ, Schulman KA, Hernandez AF. Early and long-term outcomes of heart failure in elderly persons, 2001-2005. Arch Intern Med. 2008 Dec 8; 168(22):2481-8. PMID: 19064833.
      Citations:    
    159. Whellan DJ. Introduction: Vasopressin therapy. Heart Fail Rev. 2009 Jun; 14(2):57-8. PMID: 18989773.
      Citations:    
    160. Kim DH, Daskalakis C, Lee AN, Adams S, Hohmann S, Silvestry SC, Medvedev S, Whellan DJ. Racial disparity in the relationship between hospital volume and mortality among patients undergoing coronary artery bypass grafting. Ann Surg. 2008 Nov; 248(5):886-92. PMID: 18948819.
      Citations:    
    161. Kim DH, Daskalakis C, Plumb JD, Adams S, Brawer R, Orr N, Hawthorne K, Toto EC, Whellan DJ. Modifiable cardiovascular risk factors among individuals in low socioeconomic communities and homeless shelters. Fam Community Health. 2008 Oct-Dec; 31(4):269-80. PMID: 18794634.
      Citations:    
    162. Kim DH, Sabour S, Sagar UN, Adams S, Whellan DJ. Prevalence of hypovitaminosis D in cardiovascular diseases (from the National Health and Nutrition Examination Survey 2001 to 2004). Am J Cardiol. 2008 Dec 1; 102(11):1540-4. PMID: 19026311.
      Citations:    
    163. Whellan DJ, O'Connor CM, Ousdigian KT, Lung TH. Rationale, design, and baseline characteristics of a Program to Assess and Review Trending INformation and Evaluate CorRelation to Symptoms in Patients with Heart Failure (PARTNERS HF). Am Heart J. 2008 Nov; 156(5):833-9, 839.e2. PMID: 19061695.
      Citations:    
    164. Bensimhon DR, Leifer ES, Ellis SJ, Fleg JL, Keteyian SJ, Piña IL, Kitzman DW, McKelvie RS, Kraus WE, Forman DE, Kao AJ, Whellan DJ, O'Connor CM, Russell SD. Reproducibility of peak oxygen uptake and other cardiopulmonary exercise testing parameters in patients with heart failure (from the Heart Failure and A Controlled Trial Investigating Outcomes of exercise traiNing). Am J Cardiol. 2008 Sep 15; 102(6):712-7. PMID: 18773994.
      Citations:    
    165. Marmor DB, Merli GJ, Whellan DJ, Andrel J, Fisicaro T, Shamimi-Noori S, Adams S, Rubin A, Feldman AM. Relationship of inferior vena cava filter usage in post-surgical patients by various surgical and medical subspecialists. Am J Cardiol. 2008 Jul 15; 102(2):226-30. PMID: 18602527.
      Citations:    
    166. Sagar UN, Ahmed MM, Adams S, Whellan DJ. Does body mass index really matter in the management of heart failure?: a review of the literature. Cardiol Rev. 2008 May-Jun; 16(3):124-8. PMID: 18414183.
      Citations:    
    167. Curtis LH, Whellan DJ, Hammill BG, Hernandez AF, Anstrom KJ, Shea AM, Schulman KA. Incidence and prevalence of heart failure in elderly persons, 1994-2003. Arch Intern Med. 2008 Feb 25; 168(4):418-24. PMID: 18299498.
      Citations:    
    168. Shah MR, Whellan DJ, Peterson ED, Nohria A, Hasselblad V, Xue Z, Bowers MT, O'Connor CM, Califf RM, Stevenson LW. Delivering heart failure disease management in 3 tertiary care centers: key clinical components and venues of care. Am Heart J. 2008 Apr; 155(4):764.e1-5. PMID: 18371490.
      Citations:    
    169. Liao L, Allen LA, Whellan DJ. Economic burden of heart failure in the elderly. Pharmacoeconomics. 2008; 26(6):447-62. PMID: 18489197.
      Citations:    
    170. Kumar S, Rubin S, Mather PJ, Whellan DJ. Hyponatremia and vasopressin antagonism in congestive heart failure. Clin Cardiol. 2007 Nov; 30(11):546-51. PMID: 17847041.
      Citations:    
    171. Mayson SE, Greenspon AJ, Adams S, Decaro MV, Sheth M, Weitz HH, Whellan DJ. The changing face of postoperative atrial fibrillation prevention: a review of current medical therapy. Cardiol Rev. 2007 Sep-Oct; 15(5):231-41. PMID: 17700382.
      Citations:    
    172. Whellan DJ, Hamad E. Natural history, adherence, or iatrogenic insult: repeat hospitalizations as a predictor of survival. Am Heart J. 2007 Aug; 154(2):203-5. PMID: 17643565.
      Citations:    
    173. Nagarakanti R, Whellan D, Rubin S, Mather PJ. Reversible cardiomyopathies. Cardiol Rev. 2007 Jul-Aug; 15(4):178-83. PMID: 17575481.
      Citations:    
    174. Bensimhon DR, Adams GL, Whellan DJ, Pagnanelli RA, Trimble M, Lee BA, Lee KL, Ellis SJ, Kraus WE, Rendall DS, Iskandrian AE, O'Connor CM, Borges-Neto S. Effect of exercise training on ventricular function, dyssynchrony, resting myocardial perfusion, and clinical outcomes in patients with heart failure: a nuclear ancillary study of Heart Failure and A Controlled Trial Investigating Outcomes of Exercise TraiNing (HF-ACTION); design and rationale. Am Heart J. 2007 Jul; 154(1):46-53. PMID: 17584550.
      Citations:    
    175. Whellan DJ, Harrington C. Diastolic heart failure and continuous hemodynamic monitoring. Am Heart J. 2007 Apr; 153(4 Suppl):6-11. PMID: 17394897.
      Citations:    
    176. Saltzman HE, Sharma K, Mather PJ, Rubin S, Adams S, Whellan DJ. Renal dysfunction in heart failure patients: what is the evidence? Heart Fail Rev. 2007 Mar; 12(1):37-47. PMID: 17393304.
      Citations:    
    177. Kalantar-Zadeh K, Kopple JD, Regidor DL, Jing J, Shinaberger CS, Aronovitz J, McAllister CJ, Whellan D, Sharma K. A1C and survival in maintenance hemodialysis patients. Diabetes Care. 2007 May; 30(5):1049-55. PMID: 17337501.
      Citations:    
    178. Whellan DJ, O'Connor CM, Lee KL, Keteyian SJ, Cooper LS, Ellis SJ, Leifer ES, Kraus WE, Kitzman DW, Blumenthal JA, Rendall DS, Houston-Miller N, Fleg JL, Schulman KA, Piña IL. Heart failure and a controlled trial investigating outcomes of exercise training (HF-ACTION): design and rationale. Am Heart J. 2007 Feb; 153(2):201-11. PMID: 17239677.
      Citations:    
    179. Liao L, Anstrom KJ, Gottdiener JS, Pappas PA, Whellan DJ, Kitzman DW, Aurigemma GP, Mark DB, Schulman KA, Jollis JG. Long-term costs and resource use in elderly participants with congestive heart failure in the Cardiovascular Health Study. Am Heart J. 2007 Feb; 153(2):245-52. PMID: 17239685.
      Citations:    
    180. Hamad E, Mather PJ, Srinivasan S, Rubin S, Whellan DJ, Feldman AM. Pharmacologic therapy of chronic heart failure. Am J Cardiovasc Drugs. 2007; 7(4):235-48. PMID: 17696565.
      Citations:    
    181. Whellan DJ, Reed SD, Liao L, Gould SD, O'connor CM, Schulman KA. Financial implications of a model heart failure disease management program for providers, hospital, healthcare systems, and payer perspectives. Am J Cardiol. 2007 Jan 15; 99(2):256-60. PMID: 17223429.
      Citations:    
    182. Sweeney MO, Ellenbogen KA, Miller EH, Sherfesee L, Sheldon T, Whellan D. The Managed Ventricular pacing versus VVI 40 Pacing (MVP) Trial: clinical background, rationale, design, and implementation. J Cardiovasc Electrophysiol. 2006 Dec; 17(12):1295-8. PMID: 17081208.
      Citations:    
    183. Whellan DJ, Tuttle RH, Velazquez EJ, Shaw LK, Jollis JG, Ellis W, O'Connor CM, Califf RM, Borges-Neto S. Predicting significant coronary artery disease in patients with left ventricular dysfunction. Am Heart J. 2006 Aug; 152(2):340-7. PMID: 16875920.
      Citations:    
    184. Moretti EW, Newman MF, Muhlbaier LH, Whellan D, Petersen RP, Rossignol D, McCants CB, Phillips-Bute B, Bennett-Guerrero E. Effects of decreased preoperative endotoxin core antibody levels on long-term mortality after coronary artery bypass graft surgery. Arch Surg. 2006 Jul; 141(7):637-41; discussion 642. PMID: 16847232.
      Citations:    
    185. Liao L, Jollis JG, Anstrom KJ, Whellan DJ, Kitzman DW, Aurigemma GP, Mark DB, Schulman KA, Gottdiener JS. Costs for heart failure with normal vs reduced ejection fraction. Arch Intern Med. 2006 Jan 9; 166(1):112-8. PMID: 16401819.
      Citations:    
    186. Feldman AM, de Lissovoy G, Bristow MR, Saxon LA, De Marco T, Kass DA, Boehmer J, Singh S, Whellan DJ, Carson P, Boscoe A, Baker TM, Gunderman MR. Cost effectiveness of cardiac resynchronization therapy in the Comparison of Medical Therapy, Pacing, and Defibrillation in Heart Failure (COMPANION) trial. J Am Coll Cardiol. 2005 Dec 20; 46(12):2311-21. PMID: 16360064.
      Citations:    
    187. Whellan DJ. Heart failure disease management: implementation and outcomes. Cardiol Rev. 2005 Sep-Oct; 13(5):231-9. PMID: 16106184.
      Citations:    
    188. Liao L, Sarria-Santamera A, Matchar DB, Huntington A, Lin S, Whellan DJ, Kong DF. Meta-analysis of survival and relief of angina pectoris after transmyocardial revascularization. Am J Cardiol. 2005 May 15; 95(10):1243-5. PMID: 15878002.
      Citations:    
    189. Whellan DJ, Hasselblad V, Peterson E, O'Connor CM, Schulman KA. Metaanalysis and review of heart failure disease management randomized controlled clinical trials. Am Heart J. 2005 Apr; 149(4):722-9. PMID: 15990759.
      Citations:    
    190. Hernandez AF, Whellan DJ, Stroud S, Sun JL, O'Connor CM, Jollis JG. Outcomes in heart failure patients after major noncardiac surgery. J Am Coll Cardiol. 2004 Oct 6; 44(7):1446-53. PMID: 15464326.
      Citations:    
    191. Borges-Neto S, Tuttle RH, Shaw LK, Smith WT, Jain D, Coleman RE, Whellan D. Outcome prediction in patients at high risk for coronary artery disease: comparison between 99mTc tetrofosmin and 99mTc sestamibi. Radiology. 2004 Jul; 232(1):58-65. PMID: 15220493.
      Citations:    
    192. Joynt KE, Whellan DJ, O'connor CM. Why is depression bad for the failing heart? A review of the mechanistic relationship between depression and heart failure. J Card Fail. 2004 Jun; 10(3):258-71. PMID: 15190537.
      Citations:    
    193. Liao L, Whellan DJ, Tabuchi K, Schulman KA. Differences in care-seeking behavior for acute chest pain in the United States and Japan. Am Heart J. 2004 Apr; 147(4):630-5. PMID: 15077077.
      Citations:    
    194. Joynt KE, Gattis WA, Hasselblad V, Fuzaylov SY, Serebruany VL, Gurbel PA, Gaulden LH, Felker GM, Whellan DJ, O'Connor CM. Effect of angiotensin-converting enzyme inhibitors, beta blockers, statins, and aspirin on C-reactive protein levels in outpatients with heart failure. Am J Cardiol. 2004 Mar 15; 93(6):783-5. PMID: 15019895.
      Citations:    
    195. Bourque JM, Velazquez EJ, Borges-Neto S, Shaw LK, Whellan DJ, O'connor CM. Clinical characteristics and referral pattern of patients with left ventricular dysfunction and significant coronary artery disease undergoing radionuclide imaging. J Nucl Cardiol. 2004 Mar-Apr; 11(2):118-25. PMID: 15052242.
      Citations:    
    196. Whellan DJ, O'Connor CM, Pina I. Training trials in heart failure: time to exercise restraint? Am Heart J. 2004 Feb; 147(2):190-2. PMID: 14760309.
      Citations:    
    197. Cowper PA, DeLong ER, Whellan DJ, Allen LaPointe NM, Califf RM. Economic effects of beta-blocker therapy in patients with heart failure. Am J Med. 2004 Jan 15; 116(2):104-11. PMID: 14715324.
      Citations:    
    198. Joynt KE, Whellan DJ, O'Connor CM. Depression and cardiovascular disease: mechanisms of interaction. Biol Psychiatry. 2003 Aug 1; 54(3):248-61. PMID: 12893101.
      Citations:    
    199. Whellan DJ, Mark DB. Quality still doesn't pay in heart failure management. J Card Fail. 2003 Aug; 9(4):263-5. PMID: 13680546.
      Citations:    
    200. Bourque JM, Velazquez EJ, Borges-Neto S, Shaw LK, Whellan DJ, O'Connor CM. Radionuclide viability testing: should it affect treatment strategy in patients with cardiomyopathy and significant coronary artery disease? Am Heart J. 2003 May; 145(5):758-67. PMID: 12766731.
      Citations:    
    201. Whellan DJ, O'Connor CM. The state of exercise training: a need for action. Am Heart J. 2002 Jul; 144(1):1-4. PMID: 12094180.
      Citations:    
    202. Whellan DJ, Cohen EJ, Matchar DB, Califf RM. Disease management in healthcare organizations: results of in-depth interviews with disease management decision makers. Am J Manag Care. 2002 Jul; 8(7):633-41. PMID: 12125803.
      Citations:    
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