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David Strayer

TitleProfessor
InstitutionThomas Jefferson University
DepartmentPathology
Address1020 Locust St.
Philadelphia PA 19107
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Dennie D, Louboutin JP, Strayer DS. Migration of bone marrow progenitor cells in the adult brain of rats and rabbits. World J Stem Cells. 2016 Apr 26; 8(4):136-57. PMID: 27114746.
      View in: PubMed
    2. Steiner JP, Bachani M, Wolfson-Stofko B, Lee MH, Wang T, Wang T, Li G, Li W, Strayer D, Haughey NJ, Nath A. Interaction of paroxetine with mitochondrial proteins mediates neuroprotection. Neurotherapeutics. 2015 Jan; 12(1):200-16. PMID: 25404050.
      View in: PubMed
    3. Louboutin JP, Strayer D. Role of Oxidative Stress in HIV-1-Associated Neurocognitive Disorder and Protection by Gene Delivery of Antioxidant Enzymes. Antioxidants (Basel). 2014; 3(4):770-97. PMID: 26785240.
      View in: PubMed
    4. Louboutin JP, Agrawal L, Reyes BA, Van Bockstaele EJ, Strayer DS. Oxidative Stress Is Associated with Neuroinflammation in Animal Models of HIV-1 Tat Neurotoxicity. Antioxidants (Basel). 2014; 3(2):414-38. PMID: 26784879.
      View in: PubMed
    5. Louboutin JP, Strayer DS. Relationship between the chemokine receptor CCR5 and microglia in neurological disorders: consequences of targeting CCR5 on neuroinflammation, neuronal death and regeneration in a model of epilepsy. CNS Neurol Disord Drug Targets. 2013 Sep; 12(6):815-29. PMID: 24047524.
      View in: PubMed
    6. Strayer DS. Raphael rubin, 1956-2011. Alcohol Clin Exp Res. 2012 Nov; 36(11):1835-6. PMID: 22998597.
      View in: PubMed
    7. Louboutin JP, Marusich E, Gao E, Agrawal L, Koch WJ, Strayer DS. Ethanol protects from injury due to ischemia and reperfusion by increasing vascularity via vascular endothelial growth factor. Alcohol. 2012 Aug; 46(5):441-54. PMID: 22560293.
      View in: PubMed
    8. Louboutin JP, Strayer DS. Blood-brain barrier abnormalities caused by HIV-1 gp120: mechanistic and therapeutic implications. ScientificWorldJournal. 2012; 2012:482575. PMID: 22448134.
      View in: PubMed
    9. Strayer DR, Carter WA. Recombinant and natural human interferons: analysis of the incidence and clinical impact of neutralizing antibodies. J Interferon Cytokine Res. 2012 Mar; 32(3):95-102. PMID: 22132684.
      View in: PubMed
    10. Louboutin JP, Reyes BA, Agrawal L, Van Bockstaele EJ, Strayer DS. HIV-1 gp120 upregulates matrix metalloproteinases and their inhibitors in a rat model of HIV encephalopathy. Eur J Neurosci. 2011 Dec; 34(12):2015-23. PMID: 22092673.
      View in: PubMed
    11. Agrawal L, Louboutin JP, Reyes BA, Van Bockstaele EJ, Strayer DS. HIV-1 Tat neurotoxicity: a model of acute and chronic exposure, and neuroprotection by gene delivery of antioxidant enzymes. Neurobiol Dis. 2012 Feb; 45(2):657-70. PMID: 22036626.
      View in: PubMed
    12. Marusich E, Louboutin JP, Chekmasova AA, Strayer DS. Lymphocyte adhesion to CCR5 ligands is reduced by anti-CCR5 gene delivery. J Neurol Sci. 2011 Sep 15; 308(1-2):25-7. PMID: 21741662.
      View in: PubMed
    13. Louboutin JP, Reyes BA, Van Bockstaele EJ, Strayer DS. Gene transfer to the cerebellum. Cerebellum. 2010 Dec; 9(4):587-97. PMID: 20700772.
      View in: PubMed
    14. Louboutin JP, Chekmasova AA, Marusich E, Chowdhury JR, Strayer DS. Efficient CNS gene delivery by intravenous injection. Nat Methods. 2010 Nov; 7(11):905-7. PMID: 20953176.
      View in: PubMed
    15. Louboutin JP, Chekmasova A, Marusich E, Agrawal L, Strayer DS. Role of CCR5 and its ligands in the control of vascular inflammation and leukocyte recruitment required for acute excitotoxic seizure induction and neural damage. FASEB J. 2011 Feb; 25(2):737-53. PMID: 20940264.
      View in: PubMed
    16. Louboutin JP, Agrawal L, Reyes BA, Van Bockstaele EJ, Strayer DS. HIV-1 gp120-induced injury to the blood-brain barrier: role of metalloproteinases 2 and 9 and relationship to oxidative stress. J Neuropathol Exp Neurol. 2010 Aug; 69(8):801-16. PMID: 20613638.
      View in: PubMed
    17. Strayer DS, Mitchell C, Maier DA, Nichols CN. Production of SV40-derived vectors. Cold Spring Harb Protoc. 2010 Jun; 2010(6):pdb.prot5436. PMID: 20516174.
      View in: PubMed
    18. Strayer DS, Mitchell C, Maier DA, Nichols CN. Titering replication-defective rSV40 vectors. Cold Spring Harb Protoc. 2010 Jun; 2010(6):pdb.prot5437. PMID: 20516175.
      View in: PubMed
    19. Louboutin JP, Reyes BA, Agrawal L, Maxwell CR, Van Bockstaele EJ, Strayer DS. Blood-brain barrier abnormalities caused by exposure to HIV-1 gp120--protection by gene delivery of antioxidant enzymes. Neurobiol Dis. 2010 May; 38(2):313-25. PMID: 20219678.
      View in: PubMed
    20. Louboutin JP, Reyes BA, Agrawal L, Van Bockstaele EJ, Strayer DS. HIV-1 gp120-induced neuroinflammation: relationship to neuron loss and protection by rSV40-delivered antioxidant enzymes. Exp Neurol. 2010 Jan; 221(1):231-45. PMID: 19913017.
      View in: PubMed
    21. Agrawal L, Louboutin JP, Marusich E, Reyes BA, Van Bockstaele EJ, Strayer DS. Dopaminergic neurotoxicity of HIV-1 gp120: reactive oxygen species as signaling intermediates. Brain Res. 2010 Jan 8; 1306:116-30. PMID: 19815008.
      View in: PubMed
    22. Louboutin JP, Agrawal L, Reyes BA, Van Bockstaele EJ, Strayer DS. A rat model of human immunodeficiency virus 1 encephalopathy using envelope glycoprotein gp120 expression delivered by SV40 vectors. J Neuropathol Exp Neurol. 2009 May; 68(5):456-73. PMID: 19525894.
      View in: PubMed
    23. Louboutin JP, Agrawal L, Reyes BA, Van Bockstaele EJ, Strayer DS. HIV-1 gp120 neurotoxicity proximally and at a distance from the point of exposure: protection by rSV40 delivery of antioxidant enzymes. Neurobiol Dis. 2009 Jun; 34(3):462-76. PMID: 19327399.
      View in: PubMed
    24. Agrawal L, Maxwell CR, Peters PJ, Clapham PR, Liu SM, Mackay CR, Strayer DS. Complexity in human immunodeficiency virus type 1 (HIV-1) co-receptor usage: roles of CCR3 and CCR5 in HIV-1 infection of monocyte-derived macrophages and brain microglia. J Gen Virol. 2009 Mar; 90(Pt 3):710-22. PMID: 19218218.
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    25. Chan K, Behling E, Strayer DS, Kocher WS, Dessain SK. Prolonged hemophagocytic lymphohistiocytosis syndrome as an initial presentation of Hodgkin lymphoma: a case report. J Med Case Rep. 2008; 2:367. PMID: 19055804.
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    26. Louboutin JP, Agrawal L, Liu B, Strayer DS. In vivo gene transfer to the CNS using recombinant SV40-derived vectors. Expert Opin Biol Ther. 2008 Sep; 8(9):1319-35. PMID: 18694352.
      View in: PubMed
    27. Louboutin JP, Liu B, Chekmasova AA, Reyes BA, van Bockstaele EJ, Strayer DS. Delivering genes to the organ-localized immune system: long-term results of direct intramarrow transduction. J Gene Med. 2007 Oct; 9(10):843-51. PMID: 17694566.
      View in: PubMed
    28. Agrawal L, Louboutin JP, Strayer DS. Preventing HIV-1 Tat-induced neuronal apoptosis using antioxidant enzymes: mechanistic and therapeutic implications. Virology. 2007 Jul 5; 363(2):462-72. PMID: 17336361.
      View in: PubMed
    29. Strayer DS, Agrawal L, Cordelier P, Liu B, Louboutin JP, Marusich E, McKee HJ, Ren CN, Strayer MS. Long-term gene expression in dividing and nondividing cells using SV40-derived vectors. Mol Biotechnol. 2006 Oct; 34(2):257-70. PMID: 17172671.
      View in: PubMed
    30. Louboutin JP, Liu B, Reyes BA, Van Bockstaele EJ, Strayer DS. Rat bone marrow progenitor cells transduced in situ by rSV40 vectors differentiate into multiple central nervous system cell lineages. Stem Cells. 2006 Dec; 24(12):2801-9. PMID: 16960137.
      View in: PubMed
    31. Cordelier P, Strayer DS. Using gene delivery to protect HIV-susceptible CNS cells: inhibiting HIV replication in microglia. Virus Res. 2006 Jun; 118(1-2):87-97. PMID: 16414141.
      View in: PubMed
    32. Liu B, Daviau J, Nichols CN, Strayer DS. In vivo gene transfer into rat bone marrow progenitor cells using rSV40 viral vectors. Blood. 2005 Oct 15; 106(8):2655-62. PMID: 15994284.
      View in: PubMed
    33. Strayer DS, Akkina R, Bunnell BA, Dropulic B, Planelles V, Pomerantz RJ, Rossi JJ, Zaia JA. Current status of gene therapy strategies to treat HIV/AIDS. Mol Ther. 2005 Jun; 11(6):823-42. PMID: 15922953.
      View in: PubMed
    34. Strayer DS, Cordelier P, Kondo R, Liu B, Matskevich AA, McKee HJ, Nichols CN, Mitchell CB, Geverd DA, White MK, Strayer MS. What they are, how they work and why they do what they do? The story of SV40-derived gene therapy vectors and what they have to offer. Curr Gene Ther. 2005 Apr; 5(2):151-65. PMID: 15853724.
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    35. Marusich EI, Parveen Z, Strayer D, Mukhtar M, Dornburg RC, Pomerantz RJ. Spleen necrosis virus-based vector delivery of anti-HIV-1 genes potently protects human hematopoietic cells from HIV-1 infection. Virology. 2005 Feb 5; 332(1):258-71. PMID: 15661158.
      View in: PubMed
    36. Strayer DS, Feitelson M, Sun B, Matskevich AA. Paradigms for conditional expression of RNA interference molecules for use against viral targets. Methods Enzymol. 2005; 392:227-41. PMID: 15644185.
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    37. Sun BS, Pan J, Clayton MM, Liu J, Yan X, Matskevich AA, Strayer DS, Gerber M, Feitelson MA. Hepatitis C virus replication in stably transfected HepG2 cells promotes hepatocellular growth and tumorigenesis. J Cell Physiol. 2004 Dec; 201(3):447-58. PMID: 15389552.
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    38. Vera M, Prieto J, Strayer DS, Fortes P. Factors influencing the production of recombinant SV40 vectors. Mol Ther. 2004 Oct; 10(4):780-91. PMID: 15451462.
      View in: PubMed
    39. Duan YY, Wu J, Zhu JL, Liu SL, Ozaki I, Strayer DS, Zern MA. Gene therapy for human alpha1-antitrypsin deficiency in an animal model using SV40-derived vectors. Gastroenterology. 2004 Oct; 127(4):1222-32. PMID: 15480999.
      View in: PubMed
    40. McKee HJ, T'sao PY, Vera M, Fortes P, Strayer DS. Durable cytotoxic immune responses against gp120 elicited by recombinant SV40 vectors encoding HIV-1 gp120 +/- IL-15. Genet Vaccines Ther. 2004 Aug 23; 2(1):10. PMID: 15324456.
      View in: PubMed
    41. Matskevich AA, Cordelier P, Strayer DS. Conditional expression of IFN-alpha and IFN-gamma activated by HBV as genetic therapy for hepatitis B. J Interferon Cytokine Res. 2003 Dec; 23(12):709-21. PMID: 14769147.
      View in: PubMed
    42. Cordelier P, Calarota SA, Pomerantz RJ, Xiaoshan J, Strayer DS. Inhibition of HIV-1 in the central nervous system by IFN-alpha2 delivered by an SV40 vector. J Interferon Cytokine Res. 2003 Sep; 23(9):477-88. PMID: 14565857.
      View in: PubMed
    43. Cordelier P, Strayer DS. Mechanisms of alpha1-antitrypsin inhibition of cellular serine proteases and HIV-1 protease that are essential for HIV-1 morphogenesis. Biochim Biophys Acta. 2003 Jul 30; 1638(3):197-207. PMID: 12878320.
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    44. Cordelier P, Van Bockstaele E, Calarota SA, Strayer DS. Inhibiting AIDS in the central nervous system: gene delivery to protect neurons from HIV. Mol Ther. 2003 Jun; 7(6):801-10. PMID: 12788654.
      View in: PubMed
    45. Cordelier P, Morse B, Strayer DS. Targeting CCR5 with siRNAs: using recombinant SV40-derived vectors to protect macrophages and microglia from R5-tropic HIV. Oligonucleotides. 2003; 13(5):281-94. PMID: 15000819.
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    46. White MK, Strayer DS. Survival signaling in type II pneumocytes activated by surfactant protein-A. Exp Cell Res. 2002 Nov 1; 280(2):270-9. PMID: 12413892.
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    47. McKee HJ, Strayer DS. Immune responses against SIV envelope glycoprotein, using recombinant SV40 as a vaccine delivery vector. Vaccine. 2002 Oct 4; 20(29-30):3613-25. PMID: 12297408.
      View in: PubMed
    48. Cordelier P, Calarota SA, Strayer DS. Trans-activated interferon-alpha2 delivered to T cells by SV40 inhibits early stages in the HIV-1 replicative cycle. J Hematother Stem Cell Res. 2002 Oct; 11(5):817-28. PMID: 12427288.
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    49. Strayer D, Branco F, Zern MA, Yam P, Calarota SA, Nichols CN, Zaia JA, Rossi J, Li H, Parashar B, Ghosh S, Chowdhury JR. Durability of transgene expression and vector integration: recombinant SV40-derived gene therapy vectors. Mol Ther. 2002 Aug; 6(2):227-37. PMID: 12161189.
      View in: PubMed
    50. Strayer DS, Zern MA, Chowdhury JR. What can SV40-derived vectors do for gene therapy? Curr Opin Mol Ther. 2002 Aug; 4(4):313-23. PMID: 12222869.
      View in: PubMed
    51. Goldstein H, Pettoello-Mantovani M, Anderson CM, Cordelier P, Pomerantz RJ, Strayer DS. Gene therapy using a simian virus 40-derived vector inhibits the development of in vivo human immunodeficiency virus type 1 infection of severe combined immunodeficiency mice implanted with human fetal thymic and liver tissue. J Infect Dis. 2002 May 15; 185(10):1425-30. PMID: 11992277.
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    52. Strayer DS, Branco F, Landré J, BouHamdan M, Shaheen F, Pomerantz RJ. Combination genetic therapy to inhibit HIV-1. Mol Ther. 2002 Jan; 5(1):33-41. PMID: 11786043.
      View in: PubMed
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