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Eric Wickstrom

TitleProfessor
InstitutionThomas Jefferson University
DepartmentBiochem & Molecular Biology
Address233 S. 10th Street
Philadelphia PA 19107
Phone215-955-4578
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    EXPERIENCE
    Jefferson Medical College, Thomas Jefferson University
    1992-1996: Professor of Pharmacology; Member, Jefferson Cancer Institute
    1997-present: Professor of Microbiology & Immunology; Member, Kimmel Cancer Center; Member, Cardeza Foundation for Hematologic Research
    2002-2005: Professor of Biochemistry & Molecular Pharmacology
    2005-present: Professor of Biochemistry & Molecular Biology
    2008-present: Adjunct Professor of Radiology, College of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania

    TEACHING EXPERIENCE (1992-present)
    A. Thomas Jefferson University
    Graduate: BI 515 General Biochemistry I; BI 612 Protein Function and Dysfunction; BI 614 Protein Structure and Function; BI 522 Experimental Principles in Molecular Biology; BI/PR 710,720,730 Biochemical/Pharmacological Literature Seminar; BT 411 Protein Purification and Characterization; GC 550 Foundations in Biomedical Sciences; GE 652 Molecular Basis of Cancer; PR 613 Structural Biology I; TE 521 Tissue Engineering

    UNIVERSITY, COLLEGE, AND DEPARTMENTAL COMMITTEE SERVICE (1992-present)
    Thomas Jefferson University
    Strategic Planning Working Group on Cancer and Cancer Biology, 2005-2006
    Clinical Cancer Research Review Committee, 1993-2009
    Animal Resources Committee, 1997-8
    Jefferson Medical College
    Committee on Faculty Affairs, 2004-2009
    Committee on Research, 2005-2008
    Kimmel Cancer Center
    2008-present: KCC Membership Committee
    2008-present: KCC Prostate Cancer Working Group
    2006-present: KCC Endocrine Mechanisms and Hormone Action in Cancer Program Committee
    Seminar Committee, 2005-present
    CD Facility Committee, 2000-2006
    Development Therapeutics Committee, 1997-2006
    NMR Facility Committee, 1993-2002
    Computer Committee, 1993-7
    Structural Biology Committee, 1993-7
    Biochemistry and Molecular Biology
    2007-present: Curriculum Committee (Chair, 2008-)

    INVITED LECTURES (2008-present)

    1. Genetic imaging. Center for Targeted Therapeutics and Translational Nanomedicine, University of Pennsylvania, Philadelphia, Pennsylvania, September 21, 2011.
    2. Three dimensional projection environment for molecular design and surgical simulation. US Army Telemedicine & Advanced Technology Research Center Product Line Review, Frederick, Maryland, March 29, 2011.
    3. Genetic imaging. Tinoco 80th Birthday Symposium, University of California, Berkeley, California, June 26, 2010.
    4. Molecular Designs for Diagnosis and Therapy, Department of Bioengineering, University of California, Merced, April 13, 2009.
    5. PET Imaging of Activated Cancer Gene mRNA in Tumors. New Frontiers of Science in Radiochemistry and Instrumentation for Radionuclide Imaging Workshop, Department of Energy, Bethesda, Maryland, November 5, 2008.
    6. Multiple Radionuclide Nanoparticles for Genetic Imaging. New Frontiers of Science in Radiochemistry and Instrumentation for Radionuclide Imaging Workshop, Department of Energy, Bethesda, Maryland, November 5, 2008.
    7. Scintigraphic imaging of KRAS mRNA in human pancreas cancer xenografts with ([111In]DO3A)n-poly(diamidopropanoyl)m-PNA-D(Cys-Ser-Lys-Cys) hybridization probes. Biophysical & Biomolecular Symposium: Targeted Delivery of Proteins and Nucleotides, American Chemical Society 236th Annual Meeting, Philadelphia, Pennsylvania, August 20, 2008.
    8. Multicomponent molecular detection of breast cancer cells using nanotube electronic devices specific for cell surface receptors. Emerging Technologies: Nanobiotechnology, American Chemical Society 236th Annual Meeting, Philadelphia, Pennsylvania, August 20, 2008.


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Oh E, Liu Y, Sonar MV, Merry DE, Wickstrom E. Fluorescence Imaging of Huntingtin mRNA Knockdown. Bioconjug Chem. 2018 Feb 26. PMID: 29451775.
      View in: PubMed
    2. Chen CP, Jing RY, Wickstrom E. Covalent Attachment of Daptomycin to Ti6Al4V Alloy Surfaces by a Thioether Linkage to Inhibit Colonization by Staphylococcus aureus. ACS Omega. 2017 Apr 30; 2(4):1645-1652. PMID: 28474012.
      View in: PubMed
    3. Trabulsi EJ, Tripathi SK, Gomella L, Solomides C, Wickstrom E, Thakur ML. Development of a voided urine assay for detecting prostate cancer non-invasively: a pilot study. BJU Int. 2017 Jun; 119(6):885-895. PMID: 28075510.
      View in: PubMed
    4. Khosravi F, Trainor PJ, Lambert C, Kloecker G, Wickstrom E, Rai SN, Panchapakesan B. Static micro-array isolation, dynamic time series classification, capture and enumeration of spiked breast cancer cells in blood: the nanotube-CTC chip. Nanotechnology. 2016 Sep 29; 27(44):44LT03. PMID: 27680886.
      View in: PubMed
    5. Khosravi F, Trainor P, Rai SN, Kloecker G, Wickstrom E, Panchapakesan B. Label-free capture of breast cancer cells spiked in buffy coats using carbon nanotube antibody micro-arrays. Nanotechnology. 2016 Apr 1; 27(13):13LT02. PMID: 26901310.
      View in: PubMed
    6. Kumar P, Tripathi SK, Chen CP, Mehta N, Paudyal B, Wickstrom E, Thakur ML. Evaluation of a PACAP Peptide Analogue Labeled with (68)Ga Using Two Different Chelating Agents. Cancer Biother Radiopharm. 2016 Feb; 31(1):29-36. PMID: 26844850.
      View in: PubMed
    7. Jin YY, Andrade J, Wickstrom E. Non-Specific Blocking of miR-17-5p Guide Strand in Triple Negative Breast Cancer Cells by Amplifying Passenger Strand Activity. PLoS One. 2015; 10(12):e0142574. PMID: 26629823.
      View in: PubMed
    8. Wickstrom E. DNA and RNA derivatives to optimize distribution and delivery. Adv Drug Deliv Rev. 2015 Jun 29; 87:25-34. PMID: 25912659.
      View in: PubMed
    9. Sonar MV, Wampole ME, Jin YY, Chen CP, Thakur ML, Wickstrom E. Fluorescence Detection of KRAS2 mRNA Hybridization in Lung Cancer Cells with PNA-Peptides Containing an Internal Thiazole Orange. Bioconjug Chem. 2014 Sep 17; 25(9):1697-708. PMID: 25180641.
      View in: PubMed
    10. Jin L, Lim M, Zhao S, Sano Y, Simone BA, Savage JE, Wickstrom E, Camphausen K, Pestell RG, Simone NL. The metastatic potential of triple-negative breast cancer is decreased via caloric restriction-mediated reduction of the miR-17~92 cluster. Breast Cancer Res Treat. 2014 Jul; 146(1):41-50. PMID: 24863696.
      View in: PubMed
    11. Paudyal B, Zhang K, Chen CP, Wampole ME, Mehta N, Mitchell EP, Gray BD, Mattis JA, Pak KY, Thakur ML, Wickstrom E. Determining efficacy of breast cancer therapy by PET imaging of HER2 mRNA. Nucl Med Biol. 2013 Nov; 40(8):994-9. PMID: 24074944.
      View in: PubMed
    12. Wampole ME, Kairys JC, Mitchell EP, Ankeny ML, Thakur ML, Wickstrom E. Consistent Surgeon Evaluations of Three-Dimensional Rendering of PET/CT Scans of the Abdomen of a Patient with a Ductal Pancreatic Mass. PLoS One. 2013; 8(9):e75237. PMID: 24086475.
      View in: PubMed
    13. Sanders JM, Wampole ME, Chen CP, Sethi D, Singh A, Dupradeau FY, Wang F, Gray BD, Thakur ML, Wickstrom E. Effects of Hypoxanthine Substitution in Peptide Nucleic Acids Targeting KRAS2 Oncogenic mRNA Molecules: Theory and Experiment. J Phys Chem B. 2013 Oct 3; 117(39):11584-95. PMID: 23972113.
      View in: PubMed
    14. Thakur ML, Zhang K, Berger A, Cavanaugh B, Kim S, Channappa C, Frangos AJ, Wickstrom E, Intenzo CM. VPAC1 Receptors for Imaging Breast Cancer: A Feasibility Study. J Nucl Med. 2013 Jul; 54(7):1019-25. PMID: 23651947.
      View in: PubMed
    15. Sanders JM, Wampole ME, Thakur ML, Wickstrom E. Molecular determinants of epidermal growth factor binding: a molecular dynamics study. PLoS One. 2013; 8(1):e54136. PMID: 23382875.
      View in: PubMed
    16. Opitz AW, Czymmek KJ, Wickstrom E, Wagner NJ. Uptake, efflux, and mass transfer coefficient of fluorescent PAMAM dendrimers into pancreatic cancer cells. Biochim Biophys Acta. 2013 Feb; 1828(2):294-301. PMID: 23022133.
      View in: PubMed
    17. Thakur ML, Zhang K, Paudyal B, Devakumar D, Covarrubias MY, Chen CP, Cheng C, Gray BD, Wickstrom E, Pak KY. Targeting apoptosis for optical imaging of infection. Mol Imaging Biol. 2012 Apr; 14(2):163-71. PMID: 21538153.
      View in: PubMed
    18. Sethi D, Chen CP, Jing RY, Thakur ML, Wickstrom E. Fluorescent peptide-PNA chimeras for imaging monoamine oxidase A mRNA in neuronal cells. Bioconjug Chem. 2012 Feb 15; 23(2):158-63. PMID: 22239616.
      View in: PubMed
    19. Wickstrom E, Chen CP, Devadhas D, Wampole M, Jin YY, Sanders JM, Kairys JC, Ankeny ML, Hu R, Barner KE, Steiner KV, Thakur ML. Three dimensional projection environment for molecular design and surgical simulation. Stud Health Technol Inform. 2011; 163:691-5. PMID: 21335882.
      View in: PubMed
    20. Panchapakesan B, Caprara R, Velasco V, Loomis J, King B, Xu P, Burkhead T, Sethu P, Stallons LJ, McGregor WG, Rai SN, Kloecker G, Wickstrom E. Micro- and nanotechnology approaches for capturing circulating tumor cells. Cancer Nanotechnol. 2010; 1(1-6):3-11. PMID: 26069475.
      View in: PubMed
    21. Chen CP, Wickstrom E. Self-protecting bactericidal titanium alloy surface formed by covalent bonding of daptomycin bisphosphonates. Bioconjug Chem. 2010 Nov 17; 21(11):1978-86. PMID: 20949909.
      View in: PubMed
    22. Opitz AW, Wickstrom E, Thakur ML, Wagner NJ. Physiologically based pharmacokinetics of molecular imaging nanoparticles for mRNA detection determined in tumor-bearing mice. Oligonucleotides. 2010 Jun; 20(3):117-25. PMID: 20406142.
      View in: PubMed
    23. Amirkhanov NV, Zhang K, Aruva MR, Thakur ML, Wickstrom E. Imaging human pancreatic cancer xenografts by targeting mutant KRAS2 mRNA with [(111)In]DOTA(n)-poly(diamidopropanoyl)(m)-KRAS2 PNA-D(Cys-Ser-Lys-Cys) nanoparticles. Bioconjug Chem. 2010 Apr 21; 21(4):731-40. PMID: 20232877.
      View in: PubMed
    24. Thakur ML, Devadhas D, Zhang K, Pestell RG, Wang C, McCue P, Wickstrom E. Imaging spontaneous MMTVneu transgenic murine mammary tumors: targeting metabolic activity versus genetic products. J Nucl Med. 2010 Jan; 51(1):106-11. PMID: 20008985.
      View in: PubMed
    25. Mukherjee A, Wickstrom E, Thakur ML. Imaging oncogene expression. Eur J Radiol. 2009 May; 70(2):265-73. PMID: 19264436.
      View in: PubMed
    26. Amirkhanov NV, Dimitrov I, Opitz AW, Zhang K, Lackey JP, Cardi CA, Lai S, Wagner NJ, Thakur ML, Wickstrom E. Design of (Gd-DO3A)n-polydiamidopropanoyl-peptide nucleic acid-D(Cys-Ser-Lys-Cys) magnetic resonance contrast agents. Biopolymers. 2008 Dec; 89(12):1061-76. PMID: 18680101.
      View in: PubMed
    27. Shao N, Wickstrom E, Panchapakesan B. Nanotube-antibody biosensor arrays for the detection of circulating breast cancer cells. Nanotechnology. 2008 Nov 19; 19(46):465101. PMID: 21836232.
      View in: PubMed
    28. Antoci V, Adams CS, Parvizi J, Davidson HM, Composto RJ, Freeman TA, Wickstrom E, Ducheyne P, Jungkind D, Shapiro IM, Hickok NJ. The inhibition of Staphylococcus epidermidis biofilm formation by vancomycin-modified titanium alloy and implications for the treatment of periprosthetic infection. Biomaterials. 2008 Dec; 29(35):4684-90. PMID: 18814909.
      View in: PubMed
    29. Zhang CM, Liu C, Christian T, Gamper H, Rozenski J, Pan D, Randolph JB, Wickstrom E, Cooperman BS, Hou YM. Pyrrolo-C as a molecular probe for monitoring conformations of the tRNA 3' end. RNA. 2008 Oct; 14(10):2245-53. PMID: 18755841.
      View in: PubMed
    30. Tian X, Michal AM, Li P, Wolfe HR, Waldman SA, Wickstrom E. STa peptide analogs for probing guanylyl cyclase C. Biopolymers. 2008; 90(5):713-23. PMID: 18615494.
      View in: PubMed
    31. Zhang K, Aruva MR, Shanthly N, Cardi CA, Rattan S, Patel C, Kim C, McCue PA, Wickstrom E, Thakur ML. PET imaging of VPAC1 expression in experimental and spontaneous prostate cancer. J Nucl Med. 2008 Jan; 49(1):112-21. PMID: 18077536.
      View in: PubMed
    32. Chen CP, Zeiger AR, Wickstrom E. Bactericidal activity of extended 9-glycyl-amido-minocyclines. Bioorg Med Chem Lett. 2007 Dec 1; 17(23):6558-62. PMID: 17933534.
      View in: PubMed
    33. Cesarone G, Edupuganti OP, Chen CP, Wickstrom E. Insulin receptor substrate 1 knockdown in human MCF7 ER+ breast cancer cells by nuclease-resistant IRS1 siRNA conjugated to a disulfide-bridged D-peptide analogue of insulin-like growth factor 1. Bioconjug Chem. 2007 Nov-Dec; 18(6):1831-40. PMID: 17922544.
      View in: PubMed
    34. Tian X, Aruva MR, Zhang K, Shanthly N, Cardi CA, Thakur ML, Wickstrom E. PET imaging of CCND1 mRNA in human MCF7 estrogen receptor positive breast cancer xenografts with oncogene-specific [64Cu]chelator-peptide nucleic acid-IGF1 analog radiohybridization probes. J Nucl Med. 2007 Oct; 48(10):1699-707. PMID: 17909257.
      View in: PubMed
    35. Zhang K, Aruva MR, Shanthly N, Cardi CA, Patel CA, Rattan S, Cesarone G, Wickstrom E, Thakur ML. Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase activating peptide (PACAP) receptor specific peptide analogues for PET imaging of breast cancer: In vitro/in vivo evaluation. Regul Pept. 2007 Dec 4; 144(1-3):91-100. PMID: 17727979.
      View in: PubMed
    36. Antoci V, King SB, Jose B, Parvizi J, Zeiger AR, Wickstrom E, Freeman TA, Composto RJ, Ducheyne P, Shapiro IM, Hickok NJ, Adams CS. Vancomycin covalently bonded to titanium alloy prevents bacterial colonization. J Orthop Res. 2007 Jul; 25(7):858-66. PMID: 17415753.
      View in: PubMed
    37. Panchapakesan B, Wickstrom E. Nanotechnology for sensing, imaging, and treating cancer. Surg Oncol Clin N Am. 2007 Apr; 16(2):293-305. PMID: 17560513.
      View in: PubMed
    38. Edupuganti OP, Antoci V, King SB, Jose B, Adams CS, Parvizi J, Shapiro IM, Zeiger AR, Hickok NJ, Wickstrom E. Covalent bonding of vancomycin to Ti6Al4V alloy pins provides long-term inhibition of Staphylococcus aureus colonization. Bioorg Med Chem Lett. 2007 May 15; 17(10):2692-6. PMID: 17369042.
      View in: PubMed
    39. Duffy KT, Wickstrom E. Zebrafish tp53 knockdown extends the survival of irradiated zebrafish embryos more effectively than the p53 inhibitor pifithrin-alpha. Cancer Biol Ther. 2007 May; 6(5):675-8. PMID: 17426443.
      View in: PubMed
    40. McAleer MF, Duffy KT, Davidson WR, Kari G, Dicker AP, Rodeck U, Wickstrom E. Antisense inhibition of cyclin D1 expression is equivalent to flavopiridol for radiosensitization of zebrafish embryos. Int J Radiat Oncol Biol Phys. 2006 Oct 1; 66(2):546-51. PMID: 16904844.
      View in: PubMed
    41. Cesarone G, Garofalo C, Abrams MT, Igoucheva O, Alexeev V, Yoon K, Surmacz E, Wickstrom E. RNAi-mediated silencing of insulin receptor substrate 1 (IRS-1) enhances tamoxifen-induced cell death in MCF-7 breast cancer cells. J Cell Biochem. 2006 May 15; 98(2):440-50. PMID: 16440325.
      View in: PubMed
    42. Quadros MR, Connelly S, Kari C, Abrams MT, Wickstrom E, Rodeck U. EGFR-dependent downregulation of Bim in epithelial cells requires MAPK and PKC-delta activities. Cancer Biol Ther. 2006 May; 5(5):498-504. PMID: 16582597.
      View in: PubMed
    43. Wickstrom E, Thakur ML. Imaging cancer gene activity in patients from outside the body. Biotechnol Healthc. 2006 Feb; 3(1):45-8. PMID: 23423635.
      View in: PubMed
    44. Tian X, Chakrabarti A, Amirkhanov NV, Aruva MR, Zhang K, Mathew B, Cardi C, Qin W, Sauter ER, Thakur ML, Wickstrom E. External imaging of CCND1, MYC, and KRAS oncogene mRNAs with tumor-targeted radionuclide-PNA-peptide chimeras. Ann N Y Acad Sci. 2005 Nov; 1059:106-44. PMID: 16382049.
      View in: PubMed
    45. Duffy KT, McAleer MF, Davidson WR, Kari L, Kari C, Liu CG, Farber SA, Cheng KC, Mest JR, Wickstrom E, Dicker AP, Rodeck U. Coordinate control of cell cycle regulatory genes in zebrafish development tested by cyclin D1 knockdown with morpholino phosphorodiamidates and hydroxyprolyl-phosphono peptide nucleic acids. Nucleic Acids Res. 2005; 33(15):4914-21. PMID: 16284195.
      View in: PubMed
    46. Jose B, Antoci V, Zeiger AR, Wickstrom E, Hickok NJ. Vancomycin covalently bonded to titanium beads kills Staphylococcus aureus. Chem Biol. 2005 Sep; 12(9):1041-8. PMID: 16183028.
      View in: PubMed
    47. Abrams MT, Robertson NM, Litwack G, Wickstrom E. Evaluation of glucocorticoid sensitivity in 697 pre-B acute lymphoblastic leukemia cells after overexpression or silencing of MAP kinase phosphatase-1. J Cancer Res Clin Oncol. 2005 Jun; 131(6):347-54. PMID: 15856297.
      View in: PubMed
    48. Efimov VA, Chakhmakhcheva OG, Wickstrom E. Synthesis and application of negatively charged PNA analogues. Nucleosides Nucleotides Nucleic Acids. 2005; 24(10-12):1853-74. PMID: 16438053.
      View in: PubMed
    49. Chakrabarti A, Aruva MR, Sajankila SP, Thakur ML, Wickstrom E. Synthesis of novel peptide nucleic acid-peptide chimera for non-invasive imaging of cancer. Nucleosides Nucleotides Nucleic Acids. 2005; 24(5-7):409-14. PMID: 16247960.
      View in: PubMed
    50. Amirkhanov NV, Wickstrom E. Synthesis of novel polydiamidopropanoate dendrimer PNA-peptide chimeras for non-invasive magnetic resonance imaging of cancer. Nucleosides Nucleotides Nucleic Acids. 2005; 24(5-7):423-6. PMID: 16247963.
      View in: PubMed
    51. Tian X, Aruva MR, Qin W, Zhu W, Sauter ER, Thakur ML, Wickstrom E. Noninvasive molecular imaging of MYC mRNA expression in human breast cancer xenografts with a [99mTc]peptide-peptide nucleic acid-peptide chimera. Bioconjug Chem. 2005 Jan-Feb; 16(1):70-9. PMID: 15656577.
      View in: PubMed
    52. Wickstrom E, Tian X, Amirkhanov NV, Chakrabarti A, Aruva MR, Rao PS, Qin W, Zhu W, Sauter ER, Thakur ML. Radionuclide-peptide nucleic acid in diagnosis and treatment of pancreatic cancer. Methods Mol Med. 2005; 106:135-91. PMID: 15375316.
      View in: PubMed
    53. Parvizi J, Wickstrom E, Zeiger AR, Adams CS, Shapiro IM, Purtill JJ, Sharkey PF, Hozack WJ, Rothman RH, Hickok NJ. Frank Stinchfield Award. Titanium surface with biologic activity against infection. Clin Orthop Relat Res. 2004 Dec; (429):33-8. PMID: 15577462.
      View in: PubMed
    54. Tian X, Aruva MR, Qin W, Zhu W, Duffy KT, Sauter ER, Thakur ML, Wickstrom E. External imaging of CCND1 cancer gene activity in experimental human breast cancer xenografts with 99mTc-peptide-peptide nucleic acid-peptide chimeras. J Nucl Med. 2004 Dec; 45(12):2070-82. PMID: 15585484.
      View in: PubMed
    55. Abrams MT, Robertson NM, Yoon K, Wickstrom E. Inhibition of glucocorticoid-induced apoptosis by targeting the major splice variants of BIM mRNA with small interfering RNA and short hairpin RNA. J Biol Chem. 2004 Dec 31; 279(53):55809-17. PMID: 15509554.
      View in: PubMed
    56. Thakur ML, Aruva MR, Gariepy J, Acton P, Rattan S, Prasad S, Wickstrom E, Alavi A. PET imaging of oncogene overexpression using 64Cu-vasoactive intestinal peptide (VIP) analog: comparison with 99mTc-VIP analog. J Nucl Med. 2004 Aug; 45(8):1381-9. PMID: 15299065.
      View in: PubMed
    57. Wickstrom E. Correspondence re: S. Heckl et al., Intracellular visualization of prostate cancer using magnetic resonance imaging. Cancer Res 2003;63:4766-72. Cancer Res. 2004 Apr 1; 64(7):2639; author reply 2639. PMID: 15059923.
      View in: PubMed
    58. Chakrabarti A, Desai P, Wickstrom E. Transposon Tn7 protein TnsD binding to Escherichia coli attTn7 DNA and its eukaryotic orthologs. Biochemistry. 2004 Mar 16; 43(10):2941-6. PMID: 15005630.
      View in: PubMed
    59. Wickstrom E, Urtishak KA, Choob M, Tian X, Sternheim N, Cross LM, Rubinstein A, Farber SA. Downregulation of gene expression with negatively charged peptide nucleic acids (PNAs) in zebrafish embryos. Methods Cell Biol. 2004; 77:137-58. PMID: 15602910.
      View in: PubMed
    60. Tian X, Aruva MR, Rao PS, Qin W, Read P, Sauter ER, Thakur ML, Wickstrom E. Imaging oncogene expression. Ann N Y Acad Sci. 2003 Dec; 1002:165-88. PMID: 14751834.
      View in: PubMed
    61. Urtishak KA, Choob M, Tian X, Sternheim N, Talbot WS, Wickstrom E, Farber SA. Targeted gene knockdown in zebrafish using negatively charged peptide nucleic acid mimics. Dev Dyn. 2003 Nov; 228(3):405-13. PMID: 14579379.
      View in: PubMed
    62. Vorobjev PE, Smith JB, Pyshnaya IA, Levina AS, Zarytova VF, Wickstrom E. Site-specific cleavage of RNA and DNA by complementary DNA--bleomycin A5 conjugates. Bioconjug Chem. 2003 Nov-Dec; 14(6):1307-13. PMID: 14624648.
      View in: PubMed
    63. Butz J, Wickstrom E, Edwards J. Characterization of mutations and loss of heterozygosity of p53 and K-ras2 in pancreatic cancer cell lines by immobilized polymerase chain reaction. BMC Biotechnol. 2003 Jul 23; 3:11. PMID: 12877750.
      View in: PubMed
    64. Tian X, Wickstrom E. Continuous solid-phase synthesis and disulfide cyclization of peptide-PNA-peptide chimeras. Org Lett. 2002 Nov 14; 4(23):4013-6. PMID: 12423074.
      View in: PubMed
    65. Le Bec C, Wickstrom E. Stereospecific Grignard-Activated Solid Phase Synthesis of DNA Methylphosphonate Dimers. J Org Chem. 1996 Jan 26; 61(2):510-513. PMID: 11666968.
      View in: PubMed
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