Kongming Wu

TitleAssoc Professor
InstitutionThomas Jefferson University
DepartmentCancer Biology
Address233 S. 10th Street
Philadelphia PA 19107
Phone215-503-9278
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Yuan X, Yi M, Zhang W, Xu L, Chu Q, Luo S, Wu K. The biology of combination immunotherapy in recurrent metastatic head and neck cancer. Int J Biochem Cell Biol. 2021 May 04; 106002. PMID: 33962022.
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    2. Yi M, Zhang J, Li A, Niu M, Yan Y, Jiao Y, Luo S, Zhou P, Wu K. The construction, expression, and enhanced anti-tumor activity of YM101: a bispecific antibody simultaneously targeting TGF-ß and PD-L1. J Hematol Oncol. 2021 Feb 16; 14(1):27. PMID: 33593403.
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    3. Yi M, Niu M, Xu L, Luo S, Wu K. Regulation of PD-L1 expression in the tumor microenvironment. J Hematol Oncol. 2021 Jan 07; 14(1):10. PMID: 33413496.
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    4. Yi M, Li A, Zhou L, Chu Q, Luo S, Wu K. Immune signature-based risk stratification and prediction of immune checkpoint inhibitor's efficacy for lung adenocarcinoma. Cancer Immunol Immunother. 2021 Jan 02. PMID: 33386920.
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    5. Yuan X, Yi M, Dong B, Chu Q, Wu K. Prognostic significance of KRT19 in Lung Squamous Cancer. J Cancer. 2021; 12(4):1240-1248. PMID: 33442422.
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    6. Xu H, Niu M, Yuan X, Wu K, Liu A. CD44 as a tumor biomarker and therapeutic target. Exp Hematol Oncol. 2020 Dec 10; 9(1):36. PMID: 33303029.
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    7. Li S, Yi M, Dong B, Jiao Y, Luo S, Wu K. The roles of exosomes in cancer drug resistance and its therapeutic application. Clin Transl Med. 2020 Dec; 10(8):e257. PMID: 33377643.
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    8. Yi M, Zhou L, Li A, Luo S, Wu K. Global burden and trend of acute lymphoblastic leukemia from 1990 to 2017. Aging (Albany NY). 2020 11 16; 12(22):22869-22891. PMID: 33203796.
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    9. Li S, Yi M, Dong B, Tan X, Luo S, Wu K. The role of exosomes in liquid biopsy for cancer diagnosis and prognosis prediction. Int J Cancer. 2020 Nov 12. PMID: 33180334.
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    10. Jin M, Yang Y, Shan Y, Chakrabarty S, Cheng Y, Soberón M, Bravo A, Liu K, Wu K, Xiao Y. Two ABC transporters are differentially involved in the toxicity of two Bacillus thuringiensis Cry1 toxins to the invasive crop-pest Spodoptera frugiperda (J. E. Smith). Pest Manag Sci. 2020 Nov 04. PMID: 33145907.
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    11. Jiao Y, Yi M, Xu L, Chu Q, Yan Y, Luo S, Wu K. CD38: Targeted therapy in multiple myeloma and therapeutic potential for solid cancers. Expert Opin Investig Drugs. 2020 Aug 21. PMID: 32822558.
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    12. Qin S, Dong B, Yi M, Chu Q, Wu K. Prognostic Values of TIM-3 Expression in Patients With Solid Tumors: A Meta-Analysis and Database Evaluation. Front Oncol. 2020; 10:1288. PMID: 32850398.
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    13. Zhang L, Liu B, Zheng W, Liu C, Zhang D, Zhao S, Li Z, Xu P, Wilson K, Withers A, Jones CM, Smith JA, Chipabika G, Kachigamba DL, Nam K, d'Alençon E, Liu B, Liang X, Jin M, Wu C, Chakrabarty S, Yang X, Jiang Y, Liu J, Liu X, Quan W, Wang G, Fan W, Qian W, Wu K, Xiao Y. Genetic structure and insecticide resistance characteristics of fall armyworm populations invading China. Mol Ecol Resour. 2020 Jul 03. PMID: 32619331.
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    14. Dong B, Yi M, Luo S, Li A, Wu K. RDGN-based predictive model for the prognosis of breast cancer. Exp Hematol Oncol. 2020; 9:13. PMID: 32550045.
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    15. Yi M, Li A, Zhou L, Chu Q, Song Y, Wu K. The global burden and attributable risk factor analysis of acute myeloid leukemia in 195 countries and territories from 1990 to 2017: estimates based on the global burden of disease study 2017. J Hematol Oncol. 2020 Jun 08; 13(1):72. PMID: 32513227.
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    16. Jin M, Cheng Y, Guo X, Li M, Chakrabarty S, Liu K, Wu K, Xiao Y. Down-regulation of lysosomal protein ABCB6 increases gossypol susceptibility in Helicoverpa armigera. Insect Biochem Mol Biol. 2020 Apr 29; 103387. PMID: 32360956.
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    17. Yi M, Xu L, Jiao Y, Luo S, Li A, Wu K. The role of cancer-derived microRNAs in cancer immune escape. J Hematol Oncol. 2020 Mar 28; 13(1):25. PMID: 32222150.
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    18. Yi M, Li T, Qin S, Yu S, Chu Q, Li A, Wu K. Identifying Tumorigenesis and Prognosis-Related Genes of Lung Adenocarcinoma: Based on Weighted Gene Coexpression Network Analysis. Biomed Res Int. 2020; 2020:4169691. PMID: 32149105.
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    19. Yu S, Yi M, Xu L, Qin S, Li A, Wu K. CXCL1 as an Unfavorable Prognosis Factor Negatively Regulated by DACH1 in Non-small Cell Lung Cancer. Front Oncol. 2019; 9:1515. PMID: 31998654.
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    20. Qin S, Yi M, Jiao D, Li A, Wu K. Distinct Roles of VEGFA and ANGPT2 in Lung Adenocarcinoma and Squamous Cell Carcinoma. J Cancer. 2020; 11(1):153-167. PMID: 31892982.
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    21. Kong D, Li A, Liu Y, Cui Q, Wang K, Zhang D, Tang J, Du Y, Liu Z, Wu G, Wu K. SIX1 Activates STAT3 Signaling to Promote the Proliferation of Thyroid Carcinoma via EYA1. Front Oncol. 2019; 9:1450. PMID: 31921695.
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    22. Yi M, Dong B, Chu Q, Wu K. Immune pressures drive the promoter hypermethylation of neoantigen genes. Exp Hematol Oncol. 2019; 8:32. PMID: 31799063.
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    23. Yi M, Dong B, Qin S, Chu Q, Wu K, Luo S. Advances and perspectives of PARP inhibitors. Exp Hematol Oncol. 2019; 8:29. PMID: 31737426.
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    24. Qin S, Xu L, Yi M, Yu S, Wu K, Luo S. Novel immune checkpoint targets: moving beyond PD-1 and CTLA-4. Mol Cancer. 2019 Nov 06; 18(1):155. PMID: 31690319.
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    25. Li A, Yi M, Qin S, Chu Q, Luo S, Wu K. Prospects for combining immune checkpoint blockade with PARP inhibition. J Hematol Oncol. 2019 Sep 14; 12(1):98. PMID: 31521196.
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    26. Yu S, Yi M, Qin S, Wu K. Next generation chimeric antigen receptor T cells: safety strategies to overcome toxicity. Mol Cancer. 2019 Aug 20; 18(1):125. PMID: 31429760.
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    27. Yu S, Zhang J, Yan Y, Yao X, Fang L, Xiong H, Liu Y, Chu Q, Zhou P, Wu K. A novel asymmetrical anti-HER2/CD3 bispecific antibody exhibits potent cytotoxicity for HER2-positive tumor cells. J Exp Clin Cancer Res. 2019 Aug 14; 38(1):355. PMID: 31412896.
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    28. Wang J, Xu D, Wang L, Cong S, Wan P, Lei C, Fabrick JA, Li X, Tabashnik BE, Wu K. Bt resistance alleles in field populations of pink bollworm from China: Similarities with the United States and decreased frequency from 2012 to 2015. Pest Manag Sci. 2019 Jul 04. PMID: 31270942.
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    29. Li A, Yi M, Qin S, Song Y, Chu Q, Wu K. Activating cGAS-STING pathway for the optimal effect of cancer immunotherapy. J Hematol Oncol. 2019 Apr 01; 12(1):35. PMID: 30935414.
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    30. Yi M, Jiao D, Qin S, Chu Q, Wu K, Li A. Synergistic effect of immune checkpoint blockade and anti-angiogenesis in cancer treatment. Mol Cancer. 2019 Mar 30; 18(1):60. PMID: 30925919.
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    31. Nie X, Guo E, Wu C, Liu D, Sun W, Zhang L, Long G, Mei Q, Wu K, Xiong H, Hu G. SALL4 induces radioresistance in nasopharyngeal carcinoma via the ATM/Chk2/p53 pathway. Cancer Med. 2019 Mar 24. PMID: 30907073.
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    32. Qin S, Li A, Yi M, Yu S, Zhang M, Wu K. Recent advances on anti-angiogenesis receptor tyrosine kinase inhibitors in cancer therapy. J Hematol Oncol. 2019 Mar 12; 12(1):27. PMID: 30866992.
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    33. Jin M, Liao C, Chakrabarty S, Wu K, Xiao Y. Comparative Proteomics of Peritrophic Matrix Provides an Insight into its Role in Cry1Ac Resistance of Cotton Bollworm Helicoverpa armigera. Toxins (Basel). 2019 Feb 02; 11(2). PMID: 30717423.
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    34. Hopper KR, Oppenheim SJ, Kuhn KL, Lanier K, Hoelmer KA, Heimpel GE, Meikle WG, O'Neil RJ, Voegtlin DG, Wu K, Woolley JB, Heraty JM. Counties not countries: Variation in host specificity among populations of an aphid parasitoid. Evol Appl. 2019 Apr; 12(4):815-829. PMID: 30976312.
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    35. Xu H, Jiao Y, Yi M, Zhao W, Wu K. EYA2 Correlates With Clinico-Pathological Features of Breast Cancer, Promotes Tumor Proliferation, and Predicts Poor Survival. Front Oncol. 2019; 9:26. PMID: 30761270.
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    36. Yi M, Jiao D, Qin S, Chu Q, Li A, Wu K. Manipulating Gut Microbiota Composition to Enhance the Therapeutic Effect of Cancer Immunotherapy. Integr Cancer Ther. 2019 Jan-Dec; 18:1534735419876351. PMID: 31517538.
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    37. Jin M, Liao C, Chakrabarty S, Zheng W, Wu K, Xiao Y. Transcriptional response of ATP-binding cassette (ABC) transporters to insecticides in the cotton bollworm, Helicoverpa armigera. Pestic Biochem Physiol. 2019 Feb; 154:46-59. PMID: 30765056.
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    38. Jiao X, Li Z, Wang M, Katiyar S, Di Sante G, Farshchian M, South AP, Cocola C, Colombo D, Reinbold R, Zucchi I, Wu K, Tabas I, Spike BT, Pestell RG. Dachshund Depletion Disrupts Mammary Gland Development and Diverts the Composition of the Mammary Gland Progenitor Pool. Stem Cell Reports. 2019 Jan 08; 12(1):135-151. PMID: 30554919.
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    39. Xu H, Jiao Y, Qin S, Zhao W, Chu Q, Wu K. Organoid technology in disease modelling, drug development, personalized treatment and regeneration medicine. Exp Hematol Oncol. 2018; 7:30. PMID: 30534474.
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    40. Yi M, Qin S, Chu Q, Wu K. The role of gut microbiota in immune checkpoint inhibitor therapy. Hepatobiliary Surg Nutr. 2018 Dec; 7(6):481-483. PMID: 30652094.
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    41. Yi M, Qin S, Zhao W, Yu S, Chu Q, Wu K. The role of neoantigen in immune checkpoint blockade therapy. Exp Hematol Oncol. 2018; 7:28. PMID: 30473928.
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    42. Xu H, Lyu X, Yi M, Zhao W, Song Y, Wu K. Organoid technology and applications in cancer research. J Hematol Oncol. 2018 Sep 15; 11(1):116. PMID: 30219074.
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    43. Yi M, Jiao D, Xu H, Liu Q, Zhao W, Han X, Wu K. Biomarkers for predicting efficacy of PD-1/PD-L1 inhibitors. Mol Cancer. 2018 Aug 23; 17(1):129. PMID: 30139382.
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    44. Jiao Y, Hu X, Peng Y, Wu K, Romeis J, Li Y. Bt rice plants may protect neighbouring non-Bt rice plants against the striped stem borer, Chilo suppressalis. Proc Biol Sci. 2018 Jul 25; 285(1883). PMID: 30051874.
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    45. Xu H, Bai X, Yu S, Liu Q, Pestell RG, Wu K. MAT1 correlates with molecular subtypes and predicts poor survival in breast cancer. Chin J Cancer Res. 2018 Jun; 30(3):351-363. PMID: 30046229.
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    46. Yan W, Wu K, Herman JG, Xu X, Yang Y, Dai G, Guo M. Retinoic acid-induced 2 (RAI2) is a novel tumor suppressor, and promoter region methylation of RAI2 is a poor prognostic marker in colorectal cancer. Clin Epigenetics. 2018; 10:69. PMID: 29796120.
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    47. Liu Q, Li A, Yu S, Qin S, Han N, Pestell RG, Han X, Wu K. DACH1 antagonizes CXCL8 to repress tumorigenesis of lung adenocarcinoma and improve prognosis. J Hematol Oncol. 2018 Apr 10; 11(1):53. PMID: 29636079.
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    48. Yi M, Yu S, Qin S, Liu Q, Xu H, Zhao W, Chu Q, Wu K. Gut microbiome modulates efficacy of immune checkpoint inhibitors. J Hematol Oncol. 2018 Mar 27; 11(1):47. PMID: 29580257.
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    49. Yuan X, Gajan A, Chu Q, Xiong H, Wu K, Wu GS. Developing TRAIL/TRAIL death receptor-based cancer therapies. Cancer Metastasis Rev. 2018 Mar 14. PMID: 29541897.
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    50. Liu Q, Yu S, Zhao W, Qin S, Chu Q, Wu K. EGFR-TKIs resistance via EGFR-independent signaling pathways. Mol Cancer. 2018 Feb 19; 17(1):53. PMID: 29455669.
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    51. Cui Q, Kong D, Li Z, Ahiable P, Wang K, Wu K, Wu G. Dachshund 1 is Differentially Expressed Between Male and Female Breast Cancer: A Matched Case-Control Study of Clinical Characteristics and Prognosis. Clin Breast Cancer. 2018 10; 18(5):e875-e882. PMID: 29478945.
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    52. Jin MH, Xiao YT, Cheng Y, Hu J, Xue CB, Wu KM. Chromosomal deletions mediated by CRISPR/Cas9 in Helicoverpa armigera. Insect Sci. 2018 Jan 23. PMID: 29359508.
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    53. Yu S, Liu Q, Han X, Qin S, Zhao W, Li A, Wu K. Development and clinical application of anti-HER2 monoclonal and bispecific antibodies for cancer treatment. Exp Hematol Oncol. 2017; 6:31. PMID: 29209558.
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    54. Yu S, Li A, Liu Q, Yuan X, Xu H, Jiao D, Pestell RG, Han X, Wu K. Recent advances of bispecific antibodies in solid tumors. J Hematol Oncol. 2017 Sep 20; 10(1):155. PMID: 28931402.
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    55. Pestell TG, Jiao X, Kumar M, Peck AR, Prisco M, Deng S, Li Z, Ertel A, Casimiro MC, Ju X, Di Rocco A, Di Sante G, Katiyar S, Shupp A, Lisanti MP, Jain P, Wu K, Rui H, Hooper DC, Yu Z, Goldman AR, Speicher DW, Laury-Kleintop L, Pestell RG. Stromal cyclin D1 promotes heterotypic immune signaling and breast cancer growth. Oncotarget. 2017 Oct 10; 8(47):81754-81775. PMID: 29137220.
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    56. Xu H, Yu S, Yuan X, Xiong J, Kuang D, Pestell RG, Wu K. DACH1 suppresses breast cancer as a negative regulator of CD44. Sci Rep. 2017 Jun 28; 7(1):4361. PMID: 28659634.
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    57. Liu Q, Yu S, Li A, Xu H, Han X, Wu K. Targeting interlukin-6 to relieve immunosuppression in tumor microenvironment. Tumour Biol. 2017 Jun; 39(6):1010428317712445. PMID: 28639898.
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    58. Tian Y, Liu Q, Wu K, Chu Q, Chen Y, Wu K. Meta-analysis comparing the efficacy of nedaplatin-based regimens between squamous cell and non-squamous cell lung cancers. Oncotarget. 2017 Sep 22; 8(37):62330-62338. PMID: 28977948.
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    59. Xu H, Yu S, Liu Q, Yuan X, Mani S, Pestell RG, Wu K. Recent advances of highly selective CDK4/6 inhibitors in breast cancer. J Hematol Oncol. 2017 Apr 24; 10(1):97. PMID: 28438180.
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    60. Yu S, Li A, Liu Q, Li T, Yuan X, Han X, Wu K. Chimeric antigen receptor T cells: a novel therapy for solid tumors. J Hematol Oncol. 2017 Mar 29; 10(1):78. PMID: 28356156.
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    61. Yuan X, Kho D, Xu J, Gajan A, Wu K, Wu GS. ONC201 activates ER stress to inhibit the growth of triple-negative breast cancer cells. Oncotarget. 2017 Mar 28; 8(13):21626-21638. PMID: 28423492.
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    62. Xu P, Yuan H, Yang X, Graham RI, Liu K, Wu K. Structural proteins of Helicoverpa armigera densovirus 2 enhance transcription of viral genes through transactivation. Arch Virol. 2017 Jun; 162(6):1745-1750. PMID: 28210815.
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    63. Xu P, Graham RI, Wilson K, Wu K. Structure and transcription of the Helicoverpa armigera densovirus (HaDV2) genome and its expression strategy in LD652 cells. Virol J. 2017 Feb 07; 14(1):23. PMID: 28173863.
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    64. Liu QQ, Zhou YQ, Liu HQ, Qiu WH, Liu H, Hu TY, Xu Q, Lv YM, Wu KM. Decreased DACH1 expression in glomerulopathy is associated with disease progression and severity. Oncotarget. 2016 Nov 19. PMID: 27888806.
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    65. Liu Q, Li A, Tian Y, Liu Y, Li T, Zhang C, Wu JD, Han X, Wu K. The expression profile and clinic significance of the SIX family in non-small cell lung cancer. J Hematol Oncol. 2016 Nov 8; 9(1):119. PMID: 27821176.
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    66. Xu P, Feuda R, Lu B, Xiao H, Graham RI, Wu K. Functional opsin retrogene in nocturnal moth. Mob DNA. 2016; 7:18. PMID: 27777631.
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    67. Tian Y, Wu K, Liu Q, Han N, Zhang L, Chu Q, Chen Y. Modification of platinum sensitivity by KEAP1/NRF2 signals in non-small cell lung cancer. J Hematol Oncol. 2016; 9(1):83. PMID: 27601007.
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    68. Liu Q, Li A, Tian Y, Wu JD, Liu Y, Li T, Chen Y, Han X, Wu K. The CXCL8-CXCR1/2 pathways in cancer. Cytokine Growth Factor Rev. 2016 Oct; 31:61-71. PMID: 27578214.
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    69. Kong D, Liu Y, Liu Q, Han N, Zhang C, Pestell RG, Wu K, Wu G. The retinal determination gene network: from developmental regulator to cancer therapeutic target. Oncotarget. 2016 Aug 02; 7(31):50755-50765. PMID: 27203207.
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    70. Xu H, Wu K, Tian Y, Liu Q, Han N, Yuan X, Zhang L, Wu GS, Wu K. CD44 correlates with clinicopathological characteristics and is upregulated by EGFR in breast cancer. Int J Oncol. 2016 Oct; 49(4):1343-50. PMID: 27499099.
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    71. Kong D, Liu Y, Li Z, Cui Q, Wang K, Wu K, Wu G. OK-432 (Sapylin) Reduces Seroma Formation After Axillary Lymphadenectomy in Breast Cancer. J Invest Surg. 2017 Feb; 30(1):1-5. PMID: 27431576.
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    72. Xu HX, Wu KJ, Tian YJ, Liu Q, Han N, He XL, Yuan X, Wu GS, Wu KM. Expression profile of SIX family members correlates with clinic-pathological features and prognosis of breast cancer: A systematic review and meta-analysis. Medicine (Baltimore). 2016 Jul; 95(27):e4085. PMID: 27399099.
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    73. Wang K, Li Z, Kong D, Cui Q, Liu Y, Zhou W, Cao S, Wu K, Wu G. Left lower limb may be a forbidden region for indwelling needle during operation. Thromb Res. 2016 Aug; 144:165-8. PMID: 27352239.
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    74. Yuan X, Ji W, Chen S, Bao Y, Tan S, Lu S, Wu K, Chu Q. A novel paclitaxel-loaded poly(d,l-lactide-co-glycolide)-Tween 80 copolymer nanoparticle overcoming multidrug resistance for lung cancer treatment. Int J Nanomedicine. 2016; 11:2119-31. PMID: 27307727.
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    75. Tian Y, Liu Q, He X, Yuan X, Chen Y, Chu Q, Wu K. Emerging roles of Nrf2 signal in non-small cell lung cancer. J Hematol Oncol. 2016; 9(1):14. PMID: 26922479.
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    76. Yue X, Zhao P, Wu K, Huang J, Zhang W, Wu Y, Liang X, He X. GRIM-19 inhibition induced autophagy through activation of ERK and HIF-1a not STAT3 in Hela cells. Tumour Biol. 2016 Jul; 37(7):9789-96. PMID: 26810068.
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    77. Xu H, Tian Y, Yuan X, Liu Y, Wu H, Liu Q, Wu GS, Wu K. Enrichment of CD44 in basal-type breast cancer correlates with EMT, cancer stem cell gene profile, and prognosis. Onco Targets Ther. 2016; 9:431-44. PMID: 26855592.
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    78. Xu H, Tian Y, Yuan X, Wu H, Liu Q, Pestell RG, Wu K. The role of CD44 in epithelial-mesenchymal transition and cancer development. Onco Targets Ther. 2015; 8:3783-92. PMID: 26719706.
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    79. Wu K, Yuan X, Pestell R. Endogenous Dach1 in cancer. Oncoscience. 2015; 2(10):803-4. PMID: 26682253.
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    80. Yuan X, Wu H, Xu H, Xiong H, Chu Q, Yu S, Wu GS, Wu K. Notch signaling: An emerging therapeutic target for cancer treatment. Cancer Lett. 2015 Dec 1; 369(1):20-7. PMID: 26341688.
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    81. Xu S, Wang T, Song W, Jiang T, Zhang F, Yin Y, Jiang SW, Wu K, Yu Z, Wang C, Chen K. The inhibitory effects of AR/miR-190a/YB-1 negative feedback loop on prostate cancer and underlying mechanism. Sci Rep. 2015; 5:13528. PMID: 26314494.
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    82. Sun W, Yuan X, Tian Y, Wu H, Xu H, Hu G, Wu K. Non-invasive approaches to monitor EGFR-TKI treatment in non-small-cell lung cancer. J Hematol Oncol. 2015; 8(1):95. PMID: 26227959.
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    83. Yuan X, Zhang M, Wu H, Xu H, Han N, Chu Q, Yu S, Chen Y, Wu K. Expression of Notch1 Correlates with Breast Cancer Progression and Prognosis. PLoS One. 2015; 10(6):e0131689. PMID: 26121683.
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    84. Liu Y, Han N, Zhou S, Zhou R, Yuan X, Xu H, Zhang C, Yin T, Wu K. The DACH/EYA/SIX gene network and its role in tumor initiation and progression. Int J Cancer. 2016 Mar 1; 138(5):1067-75. PMID: 26096807.
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    85. Liu Y, Kong D, Wu H, Yuan X, Xu H, Zhang C, Wu G, Wu K. Interplay of retinal determination gene network with TGF-ß signaling pathway in epithelial-mesenchymal transition. Stem Cell Investig. 2015; 2:12. PMID: 27358880.
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    86. Yuan X, Wu H, Xu H, Han N, Chu Q, Yu S, Chen Y, Wu K. Meta-analysis reveals the correlation of Notch signaling with non-small cell lung cancer progression and prognosis. Sci Rep. 2015; 5:10338. PMID: 25996086.
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    87. Liu Y, Zhou R, Yuan X, Han N, Zhou S, Xu H, Guo M, Yu S, Zhang C, Yin T, Wu K. DACH1 is a novel predictive and prognostic biomarker in hepatocellular carcinoma as a negative regulator of Wnt/ß-catenin signaling. Oncotarget. 2015 Apr 20; 6(11):8621-34. PMID: 25940701.
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    88. Han N, Yuan X, Wu H, Xu H, Chu Q, Guo M, Yu S, Chen Y, Wu K. DACH1 inhibits lung adenocarcinoma invasion and tumor growth by repressing CXCL5 signaling. Oncotarget. 2015 Mar 20; 6(8):5877-88. PMID: 25788272.
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    89. Chen K, Wu K, Jiao X, Wang L, Ju X, Wang M, Di Sante G, Xu S, Wang Q, Li K, Sun X, Xu C, Li Z, Casimiro MC, Ertel A, Addya S, McCue PA, Lisanti MP, Wang C, Davis RJ, Mardon G, Pestell RG. The Endogenous Cell-Fate Factor Dachshund Restrains Prostate Epithelial Cell Migration via Repression of Cytokine Secretion via a CXCL Signaling Module. Cancer Res. 2015 May 15; 75(10):1992-2004. PMID: 25769723.
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    90. Yuan X, Wu H, Han N, Xu H, Chu Q, Yu S, Chen Y, Wu K. Notch signaling and EMT in non-small cell lung cancer: biological significance and therapeutic application. J Hematol Oncol. 2014; 7(1):87. PMID: 25477004.
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    91. Wang T, Guo S, Liu Z, Wu L, Li M, Yang J, Chen R, Liu X, Xu H, Cai S, Chen H, Li W, Xu S, Wang L, Hu Z, Zhuang Q, Wang L, Wu K, Liu J, Ye Z, Ji JY, Wang C, Chen K. CAMK2N1 inhibits prostate cancer progression through androgen receptor-dependent signaling. Oncotarget. 2014 Nov 15; 5(21):10293-306. PMID: 25296973.
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    92. Chu Q, Han N, Yuan X, Nie X, Wu H, Chen Y, Guo M, Yu S, Wu K. DACH1 inhibits cyclin D1 expression, cellular proliferation and tumor growth of renal cancer cells. J Hematol Oncol. 2014; 7(1):73. PMID: 25322986.
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    93. Cao G, Feng H, Guo F, Wu K, Li X, Liang G, Desneux N. Quantitative Analysis of Fitness Costs Associated with the Development of Resistance to the Bt Toxin Cry1Ac in Helicoverpa armigera. Sci Rep. 2014; 4:5629. PMID: 25005122.
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    94. Yan W, Wu K, Herman JG, Brock MV, Zhou Y, Lu Y, Zhang Z, Yang Y, Guo M. Epigenetic silencing of DACH1 induces the invasion and metastasis of gastric cancer by activating TGF-ß signalling. J Cell Mol Med. 2014 Dec; 18(12):2499-511. PMID: 24912879.
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    95. Wu L, Herman JG, Brock MV, Wu K, Mao G, Yan W, Nie Y, Liang H, Zhan Q, Li W, Guo M. Silencing DACH1 promotes esophageal cancer growth by inhibiting TGF-ß signaling. PLoS One. 2014; 9(4):e95509. PMID: 24743895.
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    96. Wu K, Chen K, Wang C, Jiao X, Wang L, Zhou J, Wang J, Li Z, Addya S, Sorensen PH, Lisanti MP, Quong A, Ertel A, Pestell RG. Cell Fate Factor DACH1 Represses YB-1-Mediated Oncogenic Transcription and Translation. Cancer Res. 2014 Feb 1; 74(3):829-39. PMID: 24335958.
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    97. Yu Z, Wang L, Wang C, Ju X, Wang M, Chen K, Loro E, Li Z, Zhang Y, Wu K, Casimiro MC, Gormley M, Ertel A, Fortina P, Chen Y, Tozeren A, Liu Z, Pestell RG. Cyclin D1 induction of Dicer governs microRNA processing and expression in breast cancer. Nat Commun. 2013 Nov 29; 4:2812. PMID: 24287487.
      Citations:    
    98. Yan W, Wu K, Herman JG, Brock MV, Fuks F, Yang L, Zhu H, Li Y, Yang Y, Guo M. Epigenetic regulation of DACH1, a novel Wnt signaling component in colorectal cancer. Epigenetics. 2013 Dec 1; 8(12):1373-83. PMID: 24149323.
      Citations:    
    99. Zhu H, Wu K, Yan W, Hu L, Yuan J, Dong Y, Li Y, Jing K, Yang Y, Guo M. Epigenetic silencing of DACH1 induces loss of transforming growth factor-ß1 antiproliferative response in human hepatocellular carcinoma. Hepatology. 2013 Dec; 58(6):2012-22. PMID: 23787902.
      Citations:    
    100. Chen K, Wu K, Gormley M, Ertel A, Wang J, Zhang W, Zhou J, Disante G, Li Z, Rui H, Quong AA, McMahon SB, Deng H, Lisanti MP, Wang C, Pestell RG. Acetylation of the Cell-Fate Factor Dachshund Determines p53 Binding and Signaling Modules in Breast Cancer. Oncotarget. 2013 Jun; 4(6):923-35. PMID: 23798621.
      Citations:    
    101. Wu K, Li Z, Cai S, Tian L, Chen K, Wang J, Hu J, Sun Y, Li X, Ertel A, Pestell RG. EYA1 Phosphatase Function Is Essential to Drive Breast Cancer Cell Proliferation through Cyclin D1. Cancer Res. 2013 Jul 15; 73(14):4488-99. PMID: 23636126.
      Citations:    
    102. Wulff JA, Buckman KA, Wu K, Heimpel GE, White JA. The endosymbiont Arsenophonus is widespread in soybean aphid, Aphis glycines, but does not provide protection from parasitoids or a fungal pathogen. PLoS One. 2013; 8(4):e62145. PMID: 23614027.
      Citations:    
    103. Chen K, Wu K, Cai S, Zhang W, Zhou J, Wang J, Ertel A, Li Z, Rui H, Quong A, Lisanti MP, Tozeren A, Tanes C, Addya S, Gormley M, Wang C, McMahon SB, Pestell RG. Dachshund Binds p53 to Block the Growth of Lung Adenocarcinoma Cells. Cancer Res. 2013 Jun 1; 73(11):3262-74. PMID: 23492369.
      Citations:    
    104. Li KM, Ren LY, Zhang YJ, Wu KM, Guo YY. Knockdown of microplitis mediator odorant receptor involved in the sensitive detection of two chemicals. J Chem Ecol. 2012 Mar; 38(3):287-94. PMID: 22402893.
      Citations:    
    105. DeAngelis T, Wu K, Pestell R, Baserga R. The type 1 insulin-like growth factor receptor and resistance to DACH1. Cell Cycle. 2011 Jun 15; 10(12):1956-9. PMID: 21558809.
      Citations:    
    106. Zhou J, Liu Y, Zhang W, Popov VM, Wang M, Pattabiraman N, Suñé C, Cvekl A, Wu K, Jiang J, Wang C, Pestell RG. Transcription elongation regulator 1 is a co-integrator of the cell fate determination factor Dachshund homolog 1. J Biol Chem. 2010 Dec 17; 285(51):40342-50. PMID: 20956529.
      Citations:    
    107. Wu K, Jiao X, Li Z, Katiyar S, Casimiro MC, Yang W, Zhang Q, Willmarth NE, Chepelev I, Crosariol M, Wei Z, Hu J, Zhao K, Pestell RG. Cell fate determination factor Dachshund reprograms breast cancer stem cell function. J Biol Chem. 2011 Jan 21; 286(3):2132-42. PMID: 20937839.
      Citations:    
    108. Zhou J, Wang C, Wang Z, Dampier W, Wu K, Casimiro MC, Chepelev I, Popov VM, Quong A, Tozeren A, Zhao K, Lisanti MP, Pestell RG. Attenuation of Forkhead signaling by the retinal determination factor DACH1. Proc Natl Acad Sci U S A. 2010 Apr 13; 107(15):6864-9. PMID: 20351289.
      Citations:    
    109. Popov VM, Wu K, Zhou J, Powell MJ, Mardon G, Wang C, Pestell RG. The Dachshund gene in development and hormone-responsive tumorigenesis. Trends Endocrinol Metab. 2010 Jan; 21(1):41-9. PMID: 19896866.
      Citations:    
    110. Zhao XC, Feng HQ, Wu B, Wu XF, Liu ZF, Wu KM, McNeil JN. Does the onset of sexual maturation terminate the expression of migratory behaviour in moths? A study of the oriental armyworm, Mythimna separata. J Insect Physiol. 2009 Nov; 55(11):1039-43. PMID: 19643107.
      Citations:    
    111. Popov VM, Zhou J, Shirley LA, Quong J, Yeow WS, Wright JA, Wu K, Rui H, Vadlamudi RK, Jiang J, Kumar R, Wang C, Pestell RG. The cell fate determination factor DACH1 is expressed in estrogen receptor-alpha-positive breast cancer and represses estrogen receptor-alpha signaling. Cancer Res. 2009 Jul 15; 69(14):5752-60. PMID: 19605405.
      Citations:    
    112. Wu K, Katiyar S, Witkiewicz A, Li A, McCue P, Song LN, Tian L, Jin M, Pestell RG. The cell fate determination factor dachshund inhibits androgen receptor signaling and prostate cancer cellular growth. Cancer Res. 2009 Apr 15; 69(8):3347-55. PMID: 19351840.
      Citations:    
    113. Liu M, Ju X, Willmarth NE, Casimiro MC, Ojeifo J, Sakamaki T, Katiyar S, Jiao X, Popov VM, Yu Z, Wu K, Joyce D, Wang C, Pestell RG. Nuclear factor-kappaB enhances ErbB2-induced mammary tumorigenesis and neoangiogenesis in vivo. Am J Pathol. 2009 May; 174(5):1910-20. PMID: 19349372.
      Citations:    
    114. Zhang Y, Wu K, Wyckhuys KA, Heimpel GE. Trade-offs between flight and fecundity in the soybean aphid (Hemiptera: Aphididae). J Econ Entomol. 2009 Feb; 102(1):133-8. PMID: 19253628.
      Citations:    
    115. Yu Z, Wang C, Wang M, Li Z, Casimiro MC, Liu M, Wu K, Whittle J, Ju X, Hyslop T, McCue P, Pestell RG. A cyclin D1/microRNA 17/20 regulatory feedback loop in control of breast cancer cell proliferation. J Cell Biol. 2008 Aug 11; 182(3):509-17. PMID: 18695042.
      Citations:    
    116. Wu K, Katiyar S, Li A, Liu M, Ju X, Popov VM, Jiao X, Lisanti MP, Casola A, Pestell RG. Dachshund inhibits oncogene-induced breast cancer cellular migration and invasion through suppression of interleukin-8. Proc Natl Acad Sci U S A. 2008 May 13; 105(19):6924-9. PMID: 18467491.
      Citations:    
    117. Sundaram K, Mani SK, Kitatani K, Wu K, Pestell RG, Reddy SV. DACH1 negatively regulates the human RANK ligand gene expression in stromal/preosteoblast cells. J Cell Biochem. 2008 Apr 15; 103(6):1747-59. PMID: 17891780.
      Citations:    
    118. Zhang Y, Wang L, Wu K, Wyckhuys KA, Heimpel GE. Flight performance of the soybean aphid, Aphis glycines (Hemiptera: Aphididae) under different temperature and humidity regimens. Environ Entomol. 2008 Apr; 37(2):301-6. PMID: 18419900.
      Citations:    
    119. Jiao X, Katiyar S, Liu M, Mueller SC, Lisanti MP, Li A, Pestell TG, Wu K, Ju X, Li Z, Wagner EF, Takeya T, Wang C, Pestell RG. Disruption of c-Jun reduces cellular migration and invasion through inhibition of c-Src and hyperactivation of ROCK II kinase. Mol Biol Cell. 2008 Apr; 19(4):1378-90. PMID: 18216279.
      Citations:    
    120. Liang GM, Wu KM, Yu HK, Li KK, Feng X, Guo YY. Changes of inheritance mode and fitness in Helicoverpa armigera (Hübner) (Lepidoptera: Noctuidae) along with its resistance evolution to Cry1Ac toxin. J Invertebr Pathol. 2008 Feb; 97(2):142-9. PMID: 17950749.
      Citations:    
    121. Miao J, Wu K, Hopper KR, Li G. Population dynamics of Aphis glycines (Homoptera: Aphididae) and impact of natural enemies in northern China. Environ Entomol. 2007 Aug; 36(4):840-8. PMID: 17716474.
      Citations:    
    122. Wu K, Liu M, Li A, Donninger H, Rao M, Jiao X, Lisanti MP, Cvekl A, Birrer M, Pestell RG. Cell fate determination factor DACH1 inhibits c-Jun-induced contact-independent growth. Mol Biol Cell. 2007 Mar; 18(3):755-67. PMID: 17182846.
      Citations:    
    123. Wu K, Li A, Rao M, Liu M, Dailey V, Yang Y, Di Vizio D, Wang C, Lisanti MP, Sauter G, Russell RG, Cvekl A, Pestell RG. DACH1 is a cell fate determination factor that inhibits cyclin D1 and breast tumor growth. Mol Cell Biol. 2006 Oct; 26(19):7116-29. PMID: 16980615.
      Citations:    
    124. Sunde JS, Donninger H, Wu K, Johnson ME, Pestell RG, Rose GS, Mok SC, Brady J, Bonome T, Birrer MJ. Expression profiling identifies altered expression of genes that contribute to the inhibition of transforming growth factor-beta signaling in ovarian cancer. Cancer Res. 2006 Sep 1; 66(17):8404-12. PMID: 16951150.
      Citations:    
    125. Hulit J, Lee RJ, Li Z, Wang C, Katiyar S, Yang J, Quong AA, Wu K, Albanese C, Russell R, Di Vizio D, Koff A, Thummala S, Zhang H, Harrell J, Sun H, Muller WJ, Inghirami G, Lisanti MP, Pestell RG. p27Kip1 repression of ErbB2-induced mammary tumor growth in transgenic mice involves Skp2 and Wnt/beta-catenin signaling. Cancer Res. 2006 Sep 1; 66(17):8529-41. PMID: 16951165.
      Citations:    
    126. Yang Y, Stopka T, Golestaneh N, Wang Y, Wu K, Li A, Chauhan BK, Gao CY, Cveklová K, Duncan MK, Pestell RG, Chepelinsky AB, Skoultchi AI, Cvekl A. Regulation of alphaA-crystallin via Pax6, c-Maf, CREB and a broad domain of lens-specific chromatin. EMBO J. 2006 May 17; 25(10):2107-18. PMID: 16675956.
      Citations:    
    127. Wu K, D'Amico M, Wang C, Albanese C, Pestell RG, Mani S. A study of cytotoxic synergy of UCN-01 and flavopiridol in syngeneic pair of cell lines. Invest New Drugs. 2005 Aug; 23(4):299-309. PMID: 16012789.
      Citations:    
    128. Ma YX, Tomita Y, Fan S, Wu K, Tong Y, Zhao Z, Song LN, Goldberg ID, Rosen EM. Structural determinants of the BRCA1 : estrogen receptor interaction. Oncogene. 2005 Mar 10; 24(11):1831-46. PMID: 15674350.
      Citations:    
    129. Fu M, Rao M, Bouras T, Wang C, Wu K, Zhang X, Li Z, Yao TP, Pestell RG. Cyclin D1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipogenesis through histone deacetylase recruitment. J Biol Chem. 2005 Apr 29; 280(17):16934-41. PMID: 15713663.
      Citations:    
    130. D'Amico M, Wu K, Fu M, Rao M, Albanese C, Russell RG, Lian H, Bregman D, White MA, Pestell RG. The inhibitor of cyclin-dependent kinase 4a/alternative reading frame (INK4a/ARF) locus encoded proteins p16INK4a and p19ARF repress cyclin D1 transcription through distinct cis elements. Cancer Res. 2004 Jun 15; 64(12):4122-30. PMID: 15205322.
      Citations:    
    131. Fu M, Rao M, Wu K, Wang C, Zhang X, Hessien M, Yeung YG, Gioeli D, Weber MJ, Pestell RG. The androgen receptor acetylation site regulates cAMP and AKT but not ERK-induced activity. J Biol Chem. 2004 Jul 9; 279(28):29436-49. PMID: 15123687.
      Citations:    
    132. Wu K, Yang Y, Wang C, Davoli MA, D'Amico M, Li A, Cveklova K, Kozmik Z, Lisanti MP, Russell RG, Cvekl A, Pestell RG. DACH1 inhibits transforming growth factor-beta signaling through binding Smad4. J Biol Chem. 2003 Dec 19; 278(51):51673-84. PMID: 14525983.
      Citations:    
    133. Wang C, Pattabiraman N, Zhou JN, Fu M, Sakamaki T, Albanese C, Li Z, Wu K, Hulit J, Neumeister P, Novikoff PM, Brownlee M, Scherer PE, Jones JG, Whitney KD, Donehower LA, Harris EL, Rohan T, Johns DC, Pestell RG. Cyclin D1 repression of peroxisome proliferator-activated receptor gamma expression and transactivation. Mol Cell Biol. 2003 Sep; 23(17):6159-73. PMID: 12917338.
      Citations:    
    134. D'Amico M, Wu K, Di Vizio D, Reutens AT, Stahl M, Fu M, Albanese C, Russell RG, Muller WJ, White M, Negassa A, Lee HW, DePinho RA, Pestell RG. The role of Ink4a/Arf in ErbB2 mammary gland tumorigenesis. Cancer Res. 2003 Jun 15; 63(12):3395-402. PMID: 12810676.
      Citations:    
    135. Neumeister P, Pixley FJ, Xiong Y, Xie H, Wu K, Ashton A, Cammer M, Chan A, Symons M, Stanley ER, Pestell RG. Cyclin D1 governs adhesion and motility of macrophages. Mol Biol Cell. 2003 May; 14(5):2005-15. PMID: 12802071.
      Citations:    
    136. Albanese C, Wu K, D'Amico M, Jarrett C, Joyce D, Hughes J, Hulit J, Sakamaki T, Fu M, Ben-Ze'ev A, Bromberg JF, Lamberti C, Verma U, Gaynor RB, Byers SW, Pestell RG. IKKalpha regulates mitogenic signaling through transcriptional induction of cyclin D1 via Tcf. Mol Biol Cell. 2003 Feb; 14(2):585-99. PMID: 12589056.
      Citations:    
    137. Wu K, Wang C, D'Amico M, Lee RJ, Albanese C, Pestell RG, Mani S. Flavopiridol and trastuzumab synergistically inhibit proliferation of breast cancer cells: association with selective cooperative inhibition of cyclin D1-dependent kinase and Akt signaling pathways. Mol Cancer Ther. 2002 Jul; 1(9):695-706. PMID: 12479366.
      Citations:    
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