Daniel T Simmons

TitleProfessor
InstitutionUniversity of Delaware
DepartmentBiological Sciences
Address63 East Delaware Ave.
Newark DE 19716
Phone302-831-8547
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    Other Positions
    TitleProfessor
    InstitutionUniversity of Delaware
    DepartmentChemistry & Biochemistry


    Collapse Research 
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    R01CA036118     (SIMMONS, DANIEL T.)Sep 1, 1985 - Jul 31, 2011
    NIH
    Structure and Function of SV40 Large Tumor Antigen
    Role: Principal Investigator

    F33CA008466     (SIMMONS, DANIEL T.)Apr 11, 1988
    NIH
    MUTAGENESIS OF SV40 TUMOR ANTIGEN GENE
    Role: Principal Investigator

    S15CA055991     (SIMMONS, DANIEL T.)Aug 1, 1991 - Jul 31, 1992
    NIH
    SMALL INSTRUMENTATION GRANT
    Role: Principal Investigator

    R55CA055234     (SIMMONS, DANIEL T.)Sep 30, 1992 - Sep 30, 1995
    NIH
    FUNCTION OF T AG-P53 COMPLEXES IN TRANSFORMATION BY SV40
    Role: Principal Investigator

    P20RR011820     (SIMMONS, DANIEL T.)Sep 30, 1996 - Aug 31, 2001
    NIH
    CONTEMPORARY APPROACHES IN MOLECULAR/STRUCTURAL BIOLOGY
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Simmons DT. Modeling of the SV40 DNA Replication Machine. Genes (Basel). 2012; 3(4):742-58. PMID: 24705083.
      Citations:    
    2. Mason AC, Roy R, Simmons DT, Wold MS. Functions of alternative replication protein A in initiation and elongation. Biochemistry. 2010 Jul 20; 49(28):5919-28. PMID: 20545304.
      Citations:    
    3. Foster EC, Simmons DT. The SV40 large T-antigen origin binding domain directly participates in DNA unwinding. Biochemistry. 2010 Mar 16; 49(10):2087-96. PMID: 20108984.
      Citations:    
    4. Wang W, Simmons DT. Simian virus 40 large T antigen can specifically unwind the central palindrome at the origin of DNA replication. J Virol. 2009 Apr; 83(7):3312-22. PMID: 19144705.
      Citations:    
    5. Khopde S, Roy R, Simmons DT. The binding of topoisomerase I to T antigen enhances the synthesis of RNA-DNA primers during simian virus 40 DNA replication. Biochemistry. 2008 Sep 9; 47(36):9653-60. PMID: 18702506.
      Citations:    
    6. Khopde S, Simmons DT. Simian virus 40 DNA replication is dependent on an interaction between topoisomerase I and the C-terminal end of T antigen. J Virol. 2008 Feb; 82(3):1136-45. PMID: 18003733.
      Citations:    
    7. Wang W, Manna D, Simmons DT. Role of the hydrophilic channels of simian virus 40 T-antigen helicase in DNA replication. J Virol. 2007 May; 81(9):4510-9. PMID: 17301125.
      Citations:    
    8. Simmons DT, Gai D, Parsons R, Debes A, Roy R. Assembly of the replication initiation complex on SV40 origin DNA. Nucleic Acids Res. 2004; 32(3):1103-12. PMID: 14960720.
      Citations:    
    9. Jiao J, Simmons DT. Nonspecific double-stranded DNA binding activity of simian virus 40 large T antigen is involved in melting and unwinding of the origin. J Virol. 2003 Dec; 77(23):12720-8. PMID: 14610194.
      Citations:    
    10. Roy R, Trowbridge P, Yang Z, Champoux JJ, Simmons DT. The cap region of topoisomerase I binds to sites near both ends of simian virus 40 T antigen. J Virol. 2003 Sep; 77(18):9809-16. PMID: 12941889.
      Citations:    
    11. Prabhu VP, Simons AM, Iwasaki H, Gai D, Simmons DT, Chen J. p53 blocks RuvAB promoted branch migration and modulates resolution of Holliday junctions by RuvC. J Mol Biol. 2002 Mar 8; 316(5):1023-32. PMID: 11884140.
      Citations:    
    12. Simmons DT, Roy R, Chen L, Gai D, Trowbridge PW. The activity of topoisomerase I is modulated by large T antigen during unwinding of the SV40 origin. J Biol Chem. 1998 Aug 7; 273(32):20390-6. PMID: 9685392.
      Citations:    
    13. Simmons DT, Trowbridge PW, Roy R. Topoisomerase I stimulates SV40 T antigen-mediated DNA replication and inhibits T antigen's ability to unwind DNA at nonorigin sites. Virology. 1998 Mar 15; 242(2):435-43. PMID: 9514975.
      Citations:    
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