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One or more keywords matched the following items that are connected to Iozzo, Renato
Item TypeName
Concept Extracellular Matrix Proteins
Academic Article Ectopic expression of decorin protein core causes a generalized growth suppression in neoplastic cells of various histogenetic origin and requires endogenous p21, an inhibitor of cyclin-dependent kinases.
Academic Article Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans.
Academic Article Cooperative action of germ-line mutations in decorin and p53 accelerates lymphoma tumorigenesis.
Academic Article Absence of decorin adversely influences tubulointerstitial fibrosis of the obstructed kidney by enhanced apoptosis and increased inflammatory reaction.
Academic Article Suppression of tumorigenicity by adenovirus-mediated gene transfer of decorin.
Academic Article Decorin suppresses tumor cell-mediated angiogenesis.
Academic Article Decorin binds to a narrow region of the epidermal growth factor (EGF) receptor, partially overlapping but distinct from the EGF-binding epitope.
Academic Article Perlecan protein core interacts with extracellular matrix protein 1 (ECM1), a glycoprotein involved in bone formation and angiogenesis.
Academic Article In vivo selective and distant killing of cancer cells using adenovirus-mediated decorin gene transfer.
Academic Article Effect of altered matrix proteins on quasilinear viscoelastic properties in transgenic mouse tail tendons.
Academic Article The role of decorin in collagen fibrillogenesis and skin homeostasis.
Academic Article Biologically active decorin is a monomer in solution.
Academic Article Strain-rate sensitive mechanical properties of tendon fascicles from mice with genetically engineered alterations in collagen and decorin.
Academic Article Regulation of fibrillin-1 by biglycan and decorin is important for tissue preservation in the kidney during pressure-induced injury.
Academic Article Investigating tendon fascicle structure-function relationships in a transgenic-age mouse model using multiple regression models.
Academic Article Protective niche for Borrelia burgdorferi to evade humoral immunity.
Academic Article Alterations in lung mechanics in decorin-deficient mice.
Academic Article Decorin deficiency leads to impaired angiogenesis in injured mouse cornea.
Academic Article Decorin prevents metastatic spreading of breast cancer.
Academic Article Decorin, a novel player in the insulin-like growth factor system.
Academic Article Influence of decorin and biglycan on mechanical properties of multiple tendons in knockout mice.
Academic Article A physiologic three-dimensional cell culture system to investigate the role of decorin in matrix organisation and cell survival.
Academic Article A role for decorin in the remodeling of myocardial infarction.
Academic Article Extracellular matrix proteoglycans control the fate of bone marrow stromal cells.
Academic Article Decorin evokes protracted internalization and degradation of the epidermal growth factor receptor via caveolar endocytosis.
Academic Article De novo decorin gene expression suppresses the malignant phenotype in human colon cancer cells.
Academic Article Decorin regulates assembly of collagen fibrils and acquisition of biomechanical properties during tendon development.
Academic Article Decorin protein core inhibits in vivo cancer growth and metabolism by hindering epidermal growth factor receptor function and triggering apoptosis via caspase-3 activation.
Academic Article A role for decorin in cutaneous wound healing and angiogenesis.
Academic Article Impaired posterior frontal sutural fusion in the biglycan/decorin double deficient mice.
Academic Article Decorin-mediated regulation of fibrillin-1 in the kidney involves the insulin-like growth factor-I receptor and Mammalian target of rapamycin.
Academic Article The glycosaminoglycan chain of decorin plays an important role in collagen fibril formation at the early stages of fibrillogenesis.
Academic Article Effect of PEEP on induced constriction is enhanced in decorin-deficient mice.
Academic Article Decorin deficiency enhances progressive nephropathy in diabetic mice.
Academic Article Decorin-transforming growth factor- interaction regulates matrix organization and mechanical characteristics of three-dimensional collagen matrices.
Academic Article Influence of cyclic strain and decorin deficiency on 3D cellularized collagen matrices.
Academic Article Genetic deficiency of decorin causes intestinal tumor formation through disruption of intestinal cell maturation.
Academic Article An antimetastatic role for decorin in breast cancer.
Academic Article Tumor microenvironment: Modulation by decorin and related molecules harboring leucine-rich tandem motifs.
Academic Article Genetic evidence for the coordinated regulation of collagen fibrillogenesis in the cornea by decorin and biglycan.
Academic Article A central role for decorin during vertebrate convergent extension.
Academic Article Genetic evidence for key roles of decorin and biglycan in dentin mineralization.
Academic Article Decorin is a novel antagonistic ligand of the Met receptor.
Academic Article Collagen fibril organization in the pregnant endometrium of decorin-deficient mice.
Academic Article Hypomethylation of the decorin proteoglycan gene in human colon cancer.
Academic Article Post-translational alterations in newly synthesized cartilage proteoglycans induced by the glutamine analogue 6-diazo-5-oxo-L-norleucine. Time course of inhibition and recovery.
Academic Article Altered expression of chondroitin sulfate proteoglycan in the stroma of human colon carcinoma. Hypomethylation of PG-40 gene correlates with increased PG-40 content and mRNA levels.
Academic Article A role for decorin in controlling proliferation, adhesion, and migration of murine embryonic fibroblasts.
Academic Article Decorin deficiency in diabetic mice: aggravation of nephropathy due to overexpression of profibrotic factors, enhanced apoptosis and mononuclear cell infiltration.
Academic Article Targeted disruption of two small leucine-rich proteoglycans, biglycan and decorin, excerpts divergent effects on enamel and dentin formation.
Academic Article Bovine pericardial proteoglycan: biochemical, immunochemical and ultrastructural studies.
Academic Article Transcriptional regulation of decorin gene expression. Induction by quiescence and repression by tumor necrosis factor-alpha.
Academic Article The murine decorin. Complete cDNA cloning, genomic organization, chromosomal assignment, and expression during organogenesis and tissue differentiation.
Academic Article A soluble ectodomain of LRIG1 inhibits cancer cell growth by attenuating basal and ligand-dependent EGFR activity.
Academic Article Structural and functional characterization of the human decorin gene promoter. A homopurine-homopyrimidine S1 nuclease-sensitive region is involved in transcriptional control.
Academic Article Altered proteoglycan gene expression and the tumor stroma.
Academic Article The human decorin gene: intron-exon organization, discovery of two alternatively spliced exons in the 5' untranslated region, and mapping of the gene to chromosome 12q23.
Academic Article Altered proteoglycan gene expression and the tumor stroma.
Academic Article The murine biglycan: complete cDNA cloning, genomic organization, promoter function, and expression.
Academic Article Decorin-induced growth suppression is associated with up-regulation of p21, an inhibitor of cyclin-dependent kinases.
Academic Article Identification of a bimodal regulatory element encompassing a canonical AP-1 binding site in the proximal promoter region of the human decorin gene.
Academic Article Model structure of decorin and implications for collagen fibrillogenesis.
Academic Article Targeted disruption of decorin leads to abnormal collagen fibril morphology and skin fragility.
Academic Article Decorin suppresses tumor cell growth by activating the epidermal growth factor receptor.
Academic Article Type VI microfilaments interact with a specific region of banded collagen fibrils in skin.
Academic Article Decorin activates the epidermal growth factor receptor and elevates cytosolic Ca2+ in A431 carcinoma cells.
Academic Article Decorin, epiphycan, and lumican genes are closely linked on murine Chromosome 10 and are deleted in lethal steel mutants.
Academic Article Decorin is a biological ligand for the epidermal growth factor receptor.
Academic Article Decorin binds near the C terminus of type I collagen.
Academic Article Activation of extracellular signal-regulated protein kinase1,2 results in down-regulation of decorin expression in fibroblasts.
Academic Article Sustained down-regulation of the epidermal growth factor receptor by decorin. A mechanism for controlling tumor growth in vivo.
Academic Article An anti-oncogenic role for decorin. Down-regulation of ErbB2 leads to growth suppression and cytodifferentiation of mammary carcinoma cells.
Academic Article Resistance to Lyme disease in decorin-deficient mice.
Academic Article A composite element binding the vitamin D receptor and the retinoic X receptor alpha mediates the transforming growth factor-beta inhibition of decorin gene expression in articular chondrocytes.
Academic Article Interaction of proteoglycans with receptor tyrosine kinases.
Academic Article Measuring single-cell cytosolic Ca2+ concentration in response to proteoglycans.
Academic Article Phenotypic effects of biglycan deficiency are linked to collagen fibril abnormalities, are synergized by decorin deficiency, and mimic Ehlers-Danlos-like changes in bone and other connective tissues.
Academic Article Steroid Hormones Are Key Modulators of Tissue Mechanical Function via Regulation of Collagen and Elastic Fibers.
Academic Article Decorin-An Antagonist of TGF-ß in Astrocytes of the Optic Nerve.
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