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One or more keywords matched the following properties of Waldman, Scott
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first name Scott
full name Scott Waldman
label Waldman, Scott
One or more keywords matched the following items that are connected to Waldman, Scott
Item TypeName
Concept Amino Acid Sequence
Concept Anti-Inflammatory Agents, Non-Steroidal
Concept Bile Acids and Salts
Concept Binding Sites
Concept Cardiovascular System
Concept Cytochrome P-450 Enzyme System
Concept Data Interpretation, Statistical
Concept Drug Administration Schedule
Concept Endocrine System
Concept Follow-Up Studies
Concept Genes
Concept Rhinitis, Allergic, Seasonal
Concept Hypnotics and Sedatives
Concept Immunization, Secondary
Concept Intestine, Small
Concept Mice, Mutant Strains
Concept Molecular Sequence Data
Concept Muscle, Smooth
Concept Neoplasm Staging
Concept Synaptic Transmission
Concept Organ Specificity
Concept Prospective Studies
Concept Prostaglandin-Endoperoxide Synthases
Concept Genes, ras
Concept Retrospective Studies
Concept Satiation
Concept Sensitivity and Specificity
Concept Severity of Illness Index
Concept Sex Characteristics
Concept Social Problems
Concept Stomach Neoplasms
Concept Sulfones
Concept Sulindac
Concept Swine
Concept Technetium Tc 99m Sulfur Colloid
Concept United States
Concept Vaccines, Synthetic
Concept Second Messenger Systems
Concept Cohort Studies
Concept Signal Transduction
Concept Survival Rate
Concept Chi-Square Distribution
Concept Case-Control Studies
Concept Single-Blind Method
Concept Granulocyte-Macrophage Colony-Stimulating Factor
Concept Drug Delivery Systems
Concept Chemotherapy, Adjuvant
Concept Protein-Serine-Threonine Kinases
Concept Genes, APC
Concept Carcinoma, Signet Ring Cell
Concept Disease-Free Survival
Concept Cross-Over Studies
Concept Statistics, Nonparametric
Concept Nitric Oxide Synthase
Concept Calcium Signaling
Concept Oligonucleotide Array Sequence Analysis
Concept Sentinel Lymph Node Biopsy
Concept Cell Surface Extensions
Concept Tumor Suppressor Proteins
Concept Stem Cell Transplantation
Concept Irritable Bowel Syndrome
Concept Receptors, Calcium-Sensing
Concept Intracellular Signaling Peptides and Proteins
Concept Cell Shape
Concept Health Status Disparities
Academic Article Taking a lesson from microbial diarrheagenesis in the management of chronic constipation.
Academic Article Clinical and translational sciences: at the intersection of molecular and individualized medicine.
Academic Article The roadmap to personalized medicine.
Academic Article Sex modulates intestinal transformation by the tumor-suppressor GCC.
Academic Article Sex modulates intestinal transformation by the tumor-suppressor GCC.
Academic Article Molecular diagnostics. At the nexus of individualized medicine, health care delivery, and public policy.
Academic Article Translational medicine in the era of health care reform.
Academic Article Applications of microRNA in cancer: Exploring the advantages of miRNA.
Academic Article Bile acids initiate lineage-addicted gastroesophageal tumorigenesis by suppressing the EGF receptor-AKT axis.
Academic Article Experimental therapeutics: a paradigm for personalized medicine.
Academic Article Selection of optimal reference genes for normalization in quantitative RT-PCR.
Academic Article Therapeutic burden in cancer revealed by molecular staging.
Academic Article Mucosally restricted antigens as novel immunological targets for antitumor therapy.
Academic Article Guanylyl cyclase C as a biomarker for targeted imaging and therapy of metastatic colorectal cancer.
Academic Article Clinical pharmacology: a paradigm for individualized medicine.
Academic Article Sizing up pharmacotherapy for obesity.
Academic Article Corruption of homeostatic mechanisms in the guanylyl cyclase C signaling pathway underlying colorectal tumorigenesis.
Academic Article Molecular therapy drives patient-centric health care paradigms.
Academic Article Clinical and translational science: from bench-bedside to global village.
Academic Article Translational medicine: path to personalized and public health.
Academic Article Molecular staging estimates occult tumor burden in colorectal cancer.
Academic Article Occult tumor burden predicts disease recurrence in lymph node-negative colorectal cancer.
Academic Article Clinical translational science 2020: disruptive innovation redefines the discovery-application enterprise.
Academic Article Contrast-enhanced ultrasound imaging of sentinel lymph nodes after peritumoral administration of Sonazoid in a melanoma tumor animal model.
Academic Article Bionic technologies transforming the science of healthcare delivery.
Academic Article Regulation of appetite to treat obesity.
Academic Article Phosphorylation of vasodilator-stimulated phosphoprotein Ser239 suppresses filopodia and invadopodia in colon cancer.
Academic Article Chronic diseases: the emerging pandemic.
Academic Article A conserved tissue-specific homeodomain-less isoform of MEIS1 is downregulated in colorectal cancer.
Academic Article A uroguanylin-GUCY2C endocrine axis regulates feeding in mice.
Academic Article Occult tumor burden contributes to racial disparities in stage-specific colorectal cancer outcomes.
Academic Article Widening the path to personalized medicine.
Academic Article GUCY2C-targeted cancer immunotherapy: past, present and future.
Academic Article Epitope-targeted cytotoxic T cells mediate lineage-specific antitumor efficacy induced by the cancer mucosa antigen GUCY2C.
Academic Article Bacterial heat-stable enterotoxins: translation of pathogenic peptides into novel targeted diagnostics and therapeutics.
Academic Article Patient-centric clinical pharmacology advances the path to personalized medicine.
Academic Article Clinical pharmacology at the core of translational science.
Academic Article Analytic lymph node number establishes staging accuracy by occult tumor burden in colorectal cancer.
Academic Article The value proposition of molecular medicine.
Academic Article GUCY2C opposes systemic genotoxic tumorigenesis by regulating AKT-dependent intestinal barrier integrity.
Academic Article Molecular staging individualizing cancer management.
Academic Article The transcription factor encyclopedia.
Academic Article GUCY2C molecular staging personalizes colorectal cancer patient management.
Academic Article Obesity pharmacotherapy: What is next?
Academic Article Dexamethasone-loaded block copolymer nanoparticles induce leukemia cell death and enhance therapeutic efficacy: a novel application in pediatric nanomedicine.
Academic Article The adipose tissue production of adiponectin is increased in end-stage renal disease.
Academic Article GUCY2C: at the intersection of obesity and cancer.
Academic Article Translational medicine individualizes healthcare discovery, development and delivery.
Academic Article Immunotherapeutic strategies to target prognostic and predictive markers of cancer.
Academic Article Guanylyl cyclase C as a biomarker in colorectal cancer.
Academic Article Where medicine, business, and public policy intersect.
Academic Article Advances in cancer immunotherapy.
Academic Article Evidence-based Guidelines for Precision Risk Stratification-Based Screening (PRSBS) for Colorectal Cancer: Lessons learned from the US Armed Forces: Consensus and Future Directions.
Academic Article Molecular staging of node negative patients with colorectal cancer.
Academic Article Colorectal cancer stem cells as biomarkers: Where it all starts?
Academic Article Cardiopoietic Stem Cell Therapy in Heart Failure: The C-CURE (Cardiopoietic stem Cell therapy in heart failURE) Multicenter Randomized Trial With Lineage-Specified Biologics.
Academic Article New advances in models and strategies for developing anti-obesity drugs.
Academic Article Colorectal cancer immunotherapy.
Academic Article Single- and multiple-dose pharmacokinetics of caspofungin in healthy men.
Academic Article Nitric oxide activation of soluble guanylyl cyclase reveals high and low affinity sites that mediate allosteric inhibition by calcium.
Academic Article In vivo imaging of human colon cancer xenografts in immunodeficient mice using a guanylyl cyclase C--specific ligand.
Academic Article A comparative molecular field analysis (COMFA) of the structural determinants of heat-stable enterotoxins mediating activation of guanylyl cyclase C.
Academic Article Soluble guanylate cyclase is allosterically inhibited by direct interaction with 2-substituted adenine nucleotides.
Academic Article Does potency predict clinical efficacy? Illustration through an antihistamine model.
Academic Article Ectopic expression of guanylyl cyclase C in adenocarcinomas of the esophagus and stomach.
Academic Article Functional and molecular characterization of beta-adrenoceptors in the internal anal sphincter.
Academic Article Pharmacokinetics of intramuscularly administered ertapenem.
Academic Article First do no harm: managing antihistamine impairment in patients with allergic rhinitis.
Academic Article Characterization of etoricoxib, a novel, selective COX-2 inhibitor.
Academic Article Pathological staging and therapy of oesophageal and gastric cancer.
Academic Article Effects of aprepitant on the pharmacokinetics of ondansetron and granisetron in healthy subjects.
Academic Article Exposure-dependent inhibition of intestinal and hepatic CYP3A4 in vivo by grapefruit juice.
Academic Article Relationship of arachidonic acid concentration to cyclooxygenase-dependent human platelet aggregation.
Academic Article Effect of mibefradil on CYP3A4 in vivo.
Academic Article Nitric oxide signaling: systems integration of oxygen balance in defense of cell integrity.
Academic Article The pharmacokinetics of nebulized nanocrystal budesonide suspension in healthy volunteers.
Academic Article Pharmacokinetics and safety of ebastine in patients with impaired hepatic function compared with healthy volunteers: a phase I open-label study.
Academic Article Indinavir and rifabutin drug interactions in healthy volunteers.
Academic Article Reciprocal regulation and integration of signaling by intracellular calcium and cyclic GMP.
Academic Article The effects of modifying in vivo cytochrome P450 3A (CYP3A) activity on etoricoxib pharmacokinetics and of etoricoxib administration on CYP3A activity.
Academic Article Potential for interactions between caspofungin and nelfinavir or rifampin.
Academic Article Markers of cell cycle-mediated drug resistance and prognosis of patients receiving preoperative combined modality therapy for rectal cancer.
Academic Article Guanylyl cyclase C is a marker of intestinal metaplasia, dysplasia, and adenocarcinoma of the gastrointestinal tract.
Academic Article Proliferative signaling by store-operated calcium channels opposes colon cancer cell cytostasis induced by bacterial enterotoxins.
Academic Article Guanylyl cyclase C: a molecular marker for staging and postoperative surveillance of patients with colorectal cancer.
Academic Article Interruption of homologous desensitization in cyclic guanosine 3',5'-monophosphate signaling restores colon cancer cytostasis by bacterial enterotoxins.
Academic Article Statistical algorithm for assuring similar efficiency in standards and samples for absolute quantification by real-time reverse transcription polymerase chain reaction.
Academic Article The putative tumor suppressor Cdx2 is overexpressed by human colorectal adenocarcinomas.
Academic Article Pharmacokinetics of aprepitant after single and multiple oral doses in healthy volunteers.
Academic Article Tumor epithelial cell matrix metalloproteinase 9 is a target for antimetastatic therapy in colorectal cancer.
Academic Article Bile acids induce ectopic expression of intestinal guanylyl cyclase C Through nuclear factor-kappaB and Cdx2 in human esophageal cells.
Academic Article Exisulind and guanylyl cyclase C induce distinct antineoplastic signaling mechanisms in human colon cancer cells.
Academic Article A validated quantitative assay to detect occult micrometastases by reverse transcriptase-polymerase chain reaction of guanylyl cyclase C in patients with colorectal cancer.
Academic Article Opportunities for near-infrared thermal ablation of colorectal metastases by guanylyl cyclase C-targeted gold nanoshells.
Academic Article Applications of nanoparticles to diagnostics and therapeutics in colorectal cancer.
Academic Article The pharmacokinetics of taurolidine metabolites in healthy volunteers.
Academic Article H-ras inhibits RhoA/ROCK leading to a decrease in the basal tone in the internal anal sphincter.
Academic Article Translating MicroRNA discovery into clinical biomarkers in cancer.
Academic Article Guanylyl cyclase C suppresses intestinal tumorigenesis by restricting proliferation and maintaining genomic integrity.
Academic Article Acquired and innate cardioprotection.
Academic Article Relative quantification based on logistic models for individual polymerase chain reactions.
Academic Article Homeostatic control of the crypt-villus axis by the bacterial enterotoxin receptor guanylyl cyclase C restricts the proliferating compartment in intestine.
Academic Article Derivation and fluidity of acutely induced dysfunctional CD8+ T cells.
Academic Article MicroRNA signatures as diagnostic and therapeutic targets.
Academic Article Enterotoxin preconditioning restores calcium-sensing receptor-mediated cytostasis in colon cancer cells.
Academic Article Guanylyl cyclase C-induced immunotherapeutic responses opposing tumor metastases without autoimmunity.
Academic Article STa peptide analogs for probing guanylyl cyclase C.
Academic Article Association of GUCY2C expression in lymph nodes with time to recurrence and disease-free survival in pN0 colorectal cancer.
Academic Article A study of microRNAs in silico and in vivo: diagnostic and therapeutic applications in cancer.
Academic Article Guanylyl cyclase C prevents colon cancer metastasis by regulating tumor epithelial cell matrix metalloproteinase-9.
Academic Article Lineage-specific T-cell responses to cancer mucosa antigen oppose systemic metastases without mucosal inflammatory disease.
Academic Article Guanylyl cyclase C in colorectal cancer: susceptibility gene and potential therapeutic target.
Academic Article Guanylyl cyclase C is a specific marker for differentiating primary and metastatic ovarian mucinous neoplasms.
Academic Article The hormone receptor GUCY2C suppresses intestinal tumor formation by inhibiting AKT signaling.
Academic Article GCC signaling in colorectal cancer: Is colorectal cancer a paracrine deficiency syndrome?
Academic Article Expression of the intestinal biomarkers Guanylyl cyclase C and CDX2 in poorly differentiated colorectal carcinomas.
Academic Article Chemiluminescence-based detection of gastrointestinal malignancies.
Academic Article GUCY2C reverse transcriptase PCR to stage pN0 colorectal cancer patients.
Academic Article Cytokine adjuvanation of therapeutic anti-tumor immunity targeted to cancer mucosa antigens.
Academic Article Translating colorectal cancer prevention through the guanylyl cyclase C signaling axis.
Academic Article Intestinal GUCY2C Prevents TGF-ß Secretion Coordinating Desmoplasia and Hyperproliferation in Colorectal Cancer.
Academic Article Genetics and genomics for the prevention and treatment of cardiovascular disease: update: a scientific statement from the american heart association.
Academic Article Reply: The C-CURE Randomized Clinical Trial (Cardiopoietic stem Cell therapy in heart failURE).
Academic Article Bridging the therapeutic continuum of drug development, regulation and use.
Academic Article Aprepitant for the prevention of nausea and vomiting associated with chemotherapy and postoperative recovery.
Academic Article Transitioning biomarkers into the clinic.
Academic Article Tumor Radiation Therapy Creates Therapeutic Vaccine Responses to the Colorectal Cancer Antigen GUCY2C.
Academic Article Mechanisms of Weight Regain following Weight Loss.
Academic Article Selective antigen-specific CD4(+) T-cell, but not CD8(+) T- or B-cell, tolerance corrupts cancer immunotherapy.
Academic Article A Novel CDX2 Isoform Regulates Alternative Splicing.
Academic Article GUCY2C lysosomotropic endocytosis delivers immunotoxin therapy to metastatic colorectal cancer.
Academic Article The Paracrine Hormone for the GUCY2C Tumor Suppressor, Guanylin, Is Universally Lost in Colorectal Cancer.
Academic Article Adiponectin receptor and adiponectin signaling in human tissue among patients with end-stage renal disease.
Academic Article The orl rat is more responsive to methacholine challenge than wild type.
Academic Article Plp1 gene duplication inhibits airway responsiveness and induces lung inflammation.
Academic Article Companion diagnostics at the intersection of personalized medicine and healthcare delivery.
Academic Article CD19-Targeted Nanodelivery of Doxorubicin Enhances Therapeutic Efficacy in B-Cell Acute Lymphoblastic Leukemia.
Academic Article Gut-Brain Endocrine Axes in Weight Regulation and Obesity Pharmacotherapy.
Academic Article Obesity-Induced Colorectal Cancer Is Driven by Caloric Silencing of the Guanylin-GUCY2C Paracrine Signaling Axis.
Academic Article Does obesity promote the development of colorectal cancer?
Academic Article GUCY2C ligand replacement to prevent colorectal cancer.
Academic Article Guanylyl Cyclase C Hormone Axis at the Intersection of Obesity and Colorectal Cancer.
Academic Article Intestinal Enteroids Model Guanylate Cyclase C-Dependent Secretion Induced by Heat-Stable Enterotoxins.
Academic Article Association of Inflammation prior to Kidney Transplantation with Post-Transplant Diabetes Mellitus.
Academic Article Guanylyl cyclase C signaling axis and colon cancer prevention.
Academic Article Current trends in targeting the hormonal regulation of appetite and energy balance to treat obesity.
Academic Article CANCER MUCOSA ANTIGENS A NOVEL PARADIGM IN CANCER IMMUNOTHERAPEUTICS.
Academic Article GUCY2C-directed CAR-T cells oppose colorectal cancer metastases without autoimmunity.
Grant (PQ1) GUCY2C hormone loss translates APC-Beta-catenin mutations into epithelial transformation
Grant Short-term Training Program in Translational Cancer Rese
Grant GUCY2C hormone signaling at the intersection of obesity and colorectal cancer(PQ1
Grant MOLECULAR CHARACTERIZATION OF E COLI TOXIN RECEPTORS
Grant Training Program in Human Investigation
Grant Occult lymph node metastases and racial disparities in colon cancer outcomes
Grant ALLOSTERIC INHIBITION OF GUANYLYL CYCLASE BY NUCLEOTIDES
Grant GUANYLYL CYCLASE C AS A BI0MARKER FOR COLORECTAL CANCER
Grant Guanylyl Cyclase C in Blood and Colorectal Cancer
Grant VITAMIN D3 25-HYDROXYLASE CHARACTERIZATION ®ULATION
Grant TRAINING PROGRAM IN HUMAN INVESTIGATION
Grant Clinical Pharmacology Training Program
Academic Article Guanylate cyclase C as a target for prevention, detection, and therapy in colorectal cancer.
Academic Article Preclinical Evaluation of a Replication-Deficient Recombinant Adenovirus Serotype 5 Vaccine Expressing Guanylate Cyclase C and the PADRE T-helper Epitope.
Academic Article Modeling qRT-PCR dynamics with application to cancer biomarker quantification.
Academic Article Cardiopoietic cell therapy for advanced ischaemic heart failure: results at 39 weeks of the prospective, randomized, double blind, sham-controlled CHART-1 clinical trial.
Academic Article Editorial (Thematic Issue: Ferid Murad, at 80: A Legacy of Science, Medicine, and Mentorship).
Academic Article Bioactivity of Oral Linaclotide in Human Colorectum for Cancer Chemoprevention.
Academic Article Prime-Boost Immunization Eliminates Metastatic Colorectal Cancer by Producing High-Avidity Effector CD8+ T Cells.
Academic Article A survey of physician receptivity to molecular diagnostic testing and readiness to act on results for early-stage colon cancer patients.
Grant Guanylin GUCY2C axis in Colorectal Cancer Initiation
Academic Article Process Improvement for Maximized Therapeutic Innovation Outcome.
Academic Article GUCY2C maintains intestinal LGR5+ stem cells by opposing ER stress.
Academic Article First-in-Human Use of a Retention-Enhanced Catheter for Endomyocardial Cell Delivery.
Academic Article Guanylate cyclase-C as a therapeutic target in gastrointestinal disorders.
Academic Article ST-Producing E. coli Oppose Carcinogen-Induced Colorectal Tumorigenesis in Mice.
Academic Article GUCY2C Signaling Opposes the Acute Radiation-Induced GI Syndrome.
Academic Article Myeloid-Specific Deletion of Zfp36 Protects Against Insulin Resistance and Fatty Liver in Diet-Induced Obese Mice.
Academic Article Human GUCY2C-Targeted Chimeric Antigen Receptor (CAR)-Expressing T Cells Eliminate Colorectal Cancer Metastases.
Academic Article Prenatal Regeneration in Clinical Practice.
Academic Article The Guanylate Cyclase C-cGMP Signaling Axis Opposes Intestinal Epithelial Injury and Neoplasia.
Academic Article Health Care Evolves From Reactive to Proactive.
Academic Article Silencing the GUCA2A-GUCY2C tumor suppressor axis in CIN, serrated and MSI colorectal neoplasia.
Academic Article Therapeutic targeting of gastrointestinal cancer stem cells.
Academic Article Split tolerance permits safe Ad5-GUCY2C-PADRE vaccine-induced T-cell responses in colon cancer patients.
Academic Article TCR Retrogenic Mice as a Model To Map Self-Tolerance Mechanisms to the Cancer Mucosa Antigen GUCY2C.
Academic Article Blunted Evoked Prouroguanylin Endocrine Secretion in Chronic Constipation.
Academic Article NHERF3 is Necessary for E. coli Heat Stable Enterotoxin (ST)-induced Inhibition of NHE3 - Differences in Signaling in Mouse Small Intestine and Caco-2 Cells.
Academic Article Biomarker targeting of colorectal cancer stem cells.
Concept Serogroup
Academic Article APC-ß-catenin-TCF signaling silences the intestinal guanylin-GUCY2C tumor suppressor axis.
Academic Article Silencing the intestinal GUCY2C tumor suppressor axis requires APC loss of heterozygosity.
Academic Article Chimeric Ad5.F35 vector evades anti-adenovirus serotype 5 neutralization opposing GUCY2C-targeted antitumor immunity.
Academic Article Cardiopoietic stem cell therapy in ischaemic heart failure: long-term clinical outcomes.
Academic Article An update on guanylyl cyclase C in the diagnosis, chemoprevention, and treatment of colorectal cancer.
Academic Article Stem cells as therapeutic targets in colorectal cancer.
Academic Article From leptin to lasers: the past and present of mouse models of obesity.
Academic Article Review article: diagnosis, management and patient perspectives of the spectrum of constipation disorders.
Academic Article Guanylyl cyclase C as a biomarker for immunotherapies for the treatment of gastrointestinal malignancies.
Academic Article The shifting paradigm of colorectal cancer treatment: a look into emerging cancer stem cell-directed therapeutics to lead the charge toward complete remission.
Academic Article Guanylyl cyclase 2C (GUCY2C) in gastrointestinal cancers: recent innovations and therapeutic potential.
Academic Article GUCY2C as a biomarker to target precision therapies for patients with colorectal cancer.
Academic Article THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Catalytic receptors.
Academic Article Emerging targets for the diagnosis of Parkinson's disease: examination of systemic biomarkers.
Academic Article Phase I double-blind, placebo-controlled trial of dolcanatide (SP-333) 27 mg to explore colorectal bioactivity in healthy volunteers.
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