"Endonucleases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze the hydrolysis of the internal bonds and thereby the formation of polynucleotides or oligonucleotides from ribo- or deoxyribonucleotide chains. EC 3.1.-.
Descriptor ID |
D004720
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MeSH Number(s) |
D08.811.277.352.355
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Endonucleases".
Below are MeSH descriptors whose meaning is more specific than "Endonucleases".
This graph shows the total number of publications written about "Endonucleases" by people in this website by year, and whether "Endonucleases" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1999 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2006 | 1 | 1 | 2 |
2008 | 0 | 1 | 1 |
2009 | 1 | 0 | 1 |
2010 | 1 | 0 | 1 |
2012 | 1 | 0 | 1 |
2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Endonucleases" by people in Profiles.
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Bepler G, Zinner RG, Moon J, Calhoun R, Kernstine K, Williams CC, Mack PC, Oliveira V, Zheng Z, Stella PJ, Redman MW, Gandara DR. A phase 2 cooperative group adjuvant trial using a biomarker-based decision algorithm in patients with stage I non-small cell lung cancer (SWOG-0720, NCT00792701). Cancer. 2014 Aug 01; 120(15):2343-51.
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Valsecchi ME, Holdbrook T, Leiby BE, Pequignot E, Littman SJ, Yeo CJ, Brody JR, Witkiewicz AK. Is there a role for the quantification of RRM1 and ERCC1 expression in pancreatic ductal adenocarcinoma? BMC Cancer. 2012; 12:104.
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Pluciennik A, Dzantiev L, Iyer RR, Constantin N, Kadyrov FA, Modrich P. PCNA function in the activation and strand direction of MutLa endonuclease in mismatch repair. Proc Natl Acad Sci U S A. 2010 Sep 14; 107(37):16066-71.
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Kandavelou K, Ramalingam S, London V, Mani M, Wu J, Alexeev V, Civin CI, Chandrasegaran S. Targeted manipulation of mammalian genomes using designed zinc finger nucleases. Biochem Biophys Res Commun. 2009 Oct 9; 388(1):56-61.
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Wongtrakool C, Roman J. Apoptosis of mesenchymal cells during the pseudoglandular stage of lung development affects branching morphogenesis. Exp Lung Res. 2008 Oct; 34(8):481-99.
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Kashkina E, Anikin M, Tahirov TH, Kochetkov SN, Vassylyev DG, Temiakov D. Elongation complexes of Thermus thermophilus RNA polymerase that possess distinct translocation conformations. Nucleic Acids Res. 2006; 34(14):4036-45.
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Igoucheva O, Alexeev V, Scharer O, Yoon K. Involvement of ERCC1/XPF and XPG in oligodeoxynucleotide-directed gene modification. Oligonucleotides. 2006; 16(1):94-104.
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Manthey GM, Bailis AM. Multiple pathways promote short-sequence recombination in Saccharomyces cerevisiae. Mol Cell Biol. 2002 Aug; 22(15):5347-56.
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Hyytinen ER, Frierson HF, Sipe TW, Li CL, Degeorges A, Sikes RA, Chung LW, Dong JT. Loss of heterozygosity and lack of mutations of the XPG/ERCC5 DNA repair gene at 13q33 in prostate cancer. Prostate. 1999 Nov 1; 41(3):190-5.
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Bailis AM, Arthur L, Rothstein R. Genome rearrangement in top3 mutants of Saccharomyces cerevisiae requires a functional RAD1 excision repair gene. Mol Cell Biol. 1992 Nov; 12(11):4988-93.