Exostoses, Multiple Hereditary
"Exostoses, Multiple Hereditary" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Hereditary disorder transmitted by an autosomal dominant gene and characterized by multiple exostoses (multiple osteochondromas) near the ends of long bones. The genetic abnormality results in a defect in the osteoclastic activity at the metaphyseal ends of the bone during the remodeling process in childhood or early adolescence. The metaphyses develop benign, bony outgrowths often capped by cartilage. A small number undergo neoplastic transformation.
| Descriptor ID |
D005097
|
| MeSH Number(s) |
C04.557.450.565.575.610.615.325 C04.700.330 C05.116.099.708.670.615.325 C05.116.540.310.500 C16.320.700.330
|
| Concept/Terms |
Exostoses, Multiple Hereditary- Exostoses, Multiple Hereditary
- Hereditary Exostoses, Multiple
- Chondrodysplasia, Hereditary Deforming
- Chondrodysplasias, Hereditary Deforming
- Deforming Chondrodysplasia, Hereditary
- Deforming Chondrodysplasias, Hereditary
- Hereditary Deforming Chondrodysplasia
- Hereditary Deforming Chondrodysplasias
- Diaphyseal Aclasis
- Aclases, Diaphyseal
- Aclasis, Diaphyseal
- Diaphyseal Aclases
- Exostoses, Familial
- Exostoses, Hereditary Multiple
- Multiple Exostoses, Hereditary
- Exostoses, Multiple
- Multiple Exostoses
- Exostoses, Multiple Cartilaginous
- Cartilaginous Exostoses, Multiple
- Exostoses, Multiple, Type I
- Exostosis, Familial
- Familial Exostosis
- Exostosis, Hereditary Multiple
- Multiple Exostosis, Hereditary
- Exostosis, Multiple
- Multiple Exostosis
- Exostosis, Multiple Cartilaginous
- Cartilaginous Exostosis, Multiple
- Multiple Cartilaginous Exostosis
- Familial Exostoses
- Hereditary Multiple Exostoses
- Hereditary Multiple Exostosis
- Multiple Cartilaginous Exostoses
- Multiple Hereditary Exostoses
- Multiple Osteochondromas
- Multiple Osteochondroma
- Osteochondroma, Multiple
- Multiple Osteochondromatosis
- Osteochondromas, Multiple
- Bessel-Hagen Disease
|
Below are MeSH descriptors whose meaning is more general than "Exostoses, Multiple Hereditary".
- Diseases [C]
- Neoplasms [C04]
- Neoplasms by Histologic Type [C04.557]
- Neoplasms, Connective and Soft Tissue [C04.557.450]
- Neoplasms, Connective Tissue [C04.557.450.565]
- Neoplasms, Bone Tissue [C04.557.450.565.575]
- Osteochondroma [C04.557.450.565.575.610]
- Osteochondromatosis [C04.557.450.565.575.610.615]
- Exostoses, Multiple Hereditary [C04.557.450.565.575.610.615.325]
- Neoplastic Syndromes, Hereditary [C04.700]
- Exostoses, Multiple Hereditary [C04.700.330]
- Musculoskeletal Diseases [C05]
- Bone Diseases [C05.116]
- Bone Diseases, Developmental [C05.116.099]
- Osteochondrodysplasias [C05.116.099.708]
- Osteochondroma [C05.116.099.708.670]
- Osteochondromatosis [C05.116.099.708.670.615]
- Exostoses, Multiple Hereditary [C05.116.099.708.670.615.325]
- Hyperostosis [C05.116.540]
- Exostoses [C05.116.540.310]
- Exostoses, Multiple Hereditary [C05.116.540.310.500]
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
- Neoplastic Syndromes, Hereditary [C16.320.700]
- Exostoses, Multiple Hereditary [C16.320.700.330]
Below are MeSH descriptors whose meaning is more specific than "Exostoses, Multiple Hereditary".
This graph shows the total number of publications written about "Exostoses, Multiple Hereditary" by people in this website by year, and whether "Exostoses, Multiple Hereditary" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 2 | 0 | 2 |
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click here.
Below are the most recent publications written about "Exostoses, Multiple Hereditary" by people in Profiles.
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Duque Orozco MDP, Abousamra O, Rogers KJ, Thacker MM. Radiographic Analysis of the Pediatric Hip Patients With Hereditary Multiple Exostoses (HME). J Pediatr Orthop. 2018 Jul; 38(6):305-311.
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Duque Orozco MDP, Abousamra O, Rogers KJ, Thacker MM. Magnetic Resonance Imaging in Symptomatic Children With Hereditary Multiple Exostoses of the Hip. J Pediatr Orthop. 2018 Feb; 38(2):116-121.
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Refsland S, Kozin SH, Zlotolow DA. Ulnar Distraction Osteogenesis in the Treatment of?Forearm Deformities in Children With Multiple?Hereditary Exostoses. J Hand Surg Am. 2016 Sep; 41(9):888-95.
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Assefa D, Murphy RC, Bergman K, Atlas AB. Three faces of costal exostoses: case series and review of literature. Pediatr Emerg Care. 2011 Dec; 27(12):1188-91.
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Patel A, Thacker MM. Cervical spinal canal compromise in a 14-year-old girl with hereditary multiple exostoses. Pediatr Radiol. 2010 Dec; 40 Suppl 1:S158.
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Kozin SH. Congenital differences about the elbow. Hand Clin. 2009 May; 25(2):277-91.
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Pandya NK, Auerbach JD, Baldwin K, Lackman RD, Chin KR. Spinal cord compression in a patient with multiple hereditary exostoses caused by breast adenocarcinoma metastatic to osteochondromas of the spine: case report. Spine (Phila Pa 1976). 2006 Nov 15; 31(24):E920-4.
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Steplewski A, Ito H, Rucker E, Brittingham RJ, Alabyeva T, Gandhi M, Ko FK, Birk DE, Jimenez SA, Fertala A. Position of single amino acid substitutions in the collagen triple helix determines their effect on structure of collagen fibrils. J Struct Biol. 2004 Dec; 148(3):326-37.