Fixatives

"Fixatives" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Agents employed in the preparation of histologic or pathologic specimens for the purpose of maintaining the existing form and structure of all of the constituent elements. Great numbers of different agents are used; some are also decalcifying and hardening agents. They must quickly kill and coagulate living tissue.

Descriptor ID	D005404
MeSH Number(s)	D27.720.355
Concept/Terms	Fixatives Fixatives Pickling Agents Pickling Agents Agents, Pickling

Below are MeSH descriptors whose meaning is more general than "Fixatives".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Specialty Uses of Chemicals [D27.720]
Fixatives [D27.720.355]

Below are MeSH descriptors whose meaning is more specific than "Fixatives".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Fixatives" by people in this website by year, and whether "Fixatives" was a major or minor topic of these publications.

Bar chart showing 11 publications over 9 distinct years, with a maximum of 2 publications in 2007 and 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1997	1	0	1
1999	0	1	1
2002	0	1	1
2007	0	2	2
2010	0	1	1
2012	1	1	2
2014	0	1	1
2019	0	1	1

Below are the most recent publications written about "Fixatives" by people in Profiles.

Mueller C, Gambarotti M, Benini S, Picci P, Righi A, Stevanin M, Hombach-Klonisch S, Henderson D, Liotta L, Espina V. Unlocking bone for proteomic analysis and FISH. Lab Invest. 2019 05; 99(5):708-721.

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Di Narzo AF, Tejpar S, Rossi S, Yan P, Popovici V, Wirapati P, Budinska E, Xie T, Estrella H, Pavlicek A, Mao M, Martin E, Scott W, Bosman FT, Roth A, Delorenzi M. Test of four colon cancer risk-scores in formalin fixed paraffin embedded microarray gene expression data. J Natl Cancer Inst. 2014 Oct; 106(10).

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Murchison AP, Bilyk JR, Eagle RC, Savino PJ. Shrinkage revisited: how long is long enough? Ophthalmic Plast Reconstr Surg. 2012 Jul-Aug; 28(4):261-3.

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Nitta H, Kelly BD, Padilla M, Wick N, Brunhoeber P, Bai I, Singh S, Ranger-Moore J, Bieniarz C, Tsuda H, Grogan TM. A gene-protein assay for human epidermal growth factor receptor 2 (HER2): brightfield tricolor visualization of HER2 protein, the HER2 gene, and chromosome 17 centromere (CEN17) in formalin-fixed, paraffin-embedded breast cancer tissue sections. Diagn Pathol. 2012 May 30; 7:60.

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Montone KT, Litzky LA, Feldman MD, Peterman H, Mathis B, Baliff J, Kaiser LR, Kucharczuk J, Nachamkin I. In situ hybridization for Coccidioides immitis 5.8S ribosomal RNA sequences in formalin-fixed, paraffin-embedded pulmonary specimens using a locked nucleic acid probe: a rapid means for identification in tissue sections. Diagn Mol Pathol. 2010 Jun; 19(2):99-104.

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Lasota J, Wasag B, Steigen SE, Limon J, Miettinen M. Improved detection of KIT exon 11 duplications in formalin-fixed, paraffin-embedded gastrointestinal stromal tumors. J Mol Diagn. 2007 Feb; 9(1):89-94.

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Coudry RA, Meireles SI, Stoyanova R, Cooper HS, Carpino A, Wang X, Engstrom PF, Clapper ML. Successful application of microarray technology to microdissected formalin-fixed, paraffin-embedded tissue. J Mol Diagn. 2007 Feb; 9(1):70-9.

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Williams SS, Zimmerman RL, Bibbo M. BCA-225 immunostain: is it of value in liver fine needle aspiration? Anal Quant Cytol Histol. 2002 Oct; 24(5):245-8.

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Solomides CC, Zimmerman R, Bibbo M. Semiquantitative assessment of c-erbB-2 (HER-2) status in cytology specimens and tissue sections from breast carcinoma. Anal Quant Cytol Histol. 1999 Apr; 21(2):121-5.

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Weidmann J, Chaubal A, Bibbo M. Cellular fixation. A study of CytoRich Red and Cytospin Collection Fluid. Acta Cytol. 1997 Jan-Feb; 41(1):182-7.

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