Gangliosides

"Gangliosides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A subclass of ACIDIC GLYCOSPHINGOLIPIDS. They contain one or more sialic acid (N-ACETYLNEURAMINIC ACID) residues. Using the Svennerholm system of abbrevations, gangliosides are designated G for ganglioside, plus subscript M, D, or T for mono-, di-, or trisialo, respectively, the subscript letter being followed by a subscript arabic numeral to indicated sequence of migration in thin-layer chromatograms. (From Oxford Dictionary of Biochemistry and Molecular Biology, 1997)

Descriptor ID	D005732
MeSH Number(s)	D09.400.410.420.025.475 D10.390.470.025.475 D10.570.877.360.025.475
Concept/Terms	Gangliosides Gangliosides Sialoglycosphingolipids

Below are MeSH descriptors whose meaning is more general than "Gangliosides".

Chemicals and Drugs [D]
Carbohydrates [D09]
Glycoconjugates [D09.400]
Glycolipids [D09.400.410]
Glycosphingolipids [D09.400.410.420]
Acidic Glycosphingolipids [D09.400.410.420.025]
Gangliosides [D09.400.410.420.025.475]
Lipids [D10]
Glycolipids [D10.390]
Glycosphingolipids [D10.390.470]
Acidic Glycosphingolipids [D10.390.470.025]
Gangliosides [D10.390.470.025.475]
Membrane Lipids [D10.570]
Sphingolipids [D10.570.877]
Glycosphingolipids [D10.570.877.360]
Acidic Glycosphingolipids [D10.570.877.360.025]
Gangliosides [D10.570.877.360.025.475]

Below are MeSH descriptors whose meaning is related to "Gangliosides".

Below are MeSH descriptors whose meaning is more specific than "Gangliosides".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Gangliosides" by people in this website by year, and whether "Gangliosides" was a major or minor topic of these publications.

Bar chart showing 13 publications over 10 distinct years, with a maximum of 2 publications in 2004 and 2008 and 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2000	1	0	1
2002	1	0	1
2003	1	0	1
2004	2	0	2
2006	1	0	1
2008	1	1	2
2009	0	1	1
2010	1	1	2
2011	1	0	1
2019	1	0	1

Below are the most recent publications written about "Gangliosides" by people in Profiles.

Bowser LE, Young M, Wenger OK, Ammous Z, Brigatti KW, Carson VJ, Moser T, Deline J, Aoki K, Morlet T, Scott EM, Puffenberger EG, Robinson DL, Hendrickson C, Salvin J, Gottlieb S, Heaps AD, Tiemeyer M, Strauss KA. Recessive GM3 synthase deficiency: Natural history, biochemistry, and therapeutic frontier. Mol Genet Metab. 2019 04; 126(4):475-488.

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De Giorgi U, Cohen EN, Gao H, Mego M, Lee BN, Lodhi A, Cristofanilli M, Lucci A, Reuben JM. Mesenchymal stem cells expressing GD2 and CD271 correlate with breast cancer-initiating cells in bone marrow. Cancer Biol Ther. 2011 May 1; 11(9):812-5.

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Zhou F, Zhang GX, Rostami A. 3G11 expression in CD4+ T cell-mediated autoimmunity and immune tolerance. Int Immunopharmacol. 2011 May; 11(5):593-6.

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Zhao Z, Ciric B, Yu S, Zhang GX, Rostami A. Targeting ganglioside epitope 3G11 on the surface of CD4+ T cells suppresses EAE by altering the Treg/Th17 cell balance. Int Immunol. 2010 Oct; 22(10):817-26.

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Dillman RO, Selvan SR, Schiltz PM, McClay EF, Barth NM, DePriest C, de Leon C, Mayorga C, Cornforth AN, Allen K. Phase II trial of dendritic cells loaded with antigens from self-renewing, proliferating autologous tumor cells as patient-specific antitumor vaccines in patients with metastatic melanoma: final report. Cancer Biother Radiopharm. 2009 Jun; 24(3):311-9.

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Marek R, Caruso M, Rostami A, Grinspan JB, Das Sarma J. Magnetic cell sorting: a fast and effective method of concurrent isolation of high purity viable astrocytes and microglia from neonatal mouse brain tissue. J Neurosci Methods. 2008 Oct 30; 175(1):108-18.

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Selvan SR, Dillman RO, Fowler AW, Carbonell DJ, Ravindranath MH. Monitoring response to treatment in melanoma patients: potential of a serum glycomic marker. Int J Cancer. 2008 Mar 15; 122(6):1374-83.

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Ravindranath MH, Muthugounder S, Presser N, Selvan SR, Santin AD, Bellone S, Saravanan TS, Morton DL. Immunogenic gangliosides in human ovarian carcinoma. Biochem Biophys Res Commun. 2007 Feb 9; 353(2):251-8.

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Ravindranath MH, Muthugounder S, Presser N, Selvan SR, Portoukalian J, Brosman S, Morton DL. Gangliosides of organ-confined versus metastatic androgen-receptor-negative prostate cancer. Biochem Biophys Res Commun. 2004 Nov 5; 324(1):154-65.

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Crespo PM, Zurita AR, Giraudo CG, Maccioni HJ, Daniotti JL. Ganglioside glycosyltransferases and newly synthesized gangliosides are excluded from detergent-insoluble complexes of Golgi membranes. Biochem J. 2004 Feb 01; 377(Pt 3):561-8.

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