"Gigantism" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The condition of accelerated and excessive GROWTH in children or adolescents who are exposed to excess HUMAN GROWTH HORMONE before the closure of EPIPHYSES. It is usually caused by somatotroph hyperplasia or a GROWTH HORMONE-SECRETING PITUITARY ADENOMA. These patients are of abnormally tall stature, more than 3 standard deviations above normal mean height for age.
| Descriptor ID |
D005877
|
| MeSH Number(s) |
C05.116.099.492 C05.116.132.479 C19.700.355.528
|
| Concept/Terms |
Gigantism- Gigantism
- Pituitary Gigantism
- Gigantism, Pituitary
|
Below are MeSH descriptors whose meaning is more general than "Gigantism".
Below are MeSH descriptors whose meaning is more specific than "Gigantism".
This graph shows the total number of publications written about "Gigantism" by people in this website by year, and whether "Gigantism" was a major or minor topic of these publications.
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Below are the most recent publications written about "Gigantism" by people in Profiles.
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Fedele M, Visone R, De Martino I, Palmieri D, Valentino T, Esposito F, Klein-Szanto A, Arra C, Ciarmiello A, Croce CM, Fusco A. Expression of a truncated Hmga1b gene induces gigantism, lipomatosis and B-cell lymphomas in mice. Eur J Cancer. 2011 Feb; 47(3):470-8.
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Battista S, Fidanza V, Fedele M, Klein-Szanto AJ, Outwater E, Brunner H, Santoro M, Croce CM, Fusco A. The expression of a truncated HMGI-C gene induces gigantism associated with lipomatosis. Cancer Res. 1999 Oct 01; 59(19):4793-7.