Granulomatous Disease, Chronic
"Granulomatous Disease, Chronic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation. When chronic granulomatous disease is caused by mutations in the CYBB gene, the condition is inherited in an X-linked recessive pattern. When chronic granulomatous disease is caused by CYBA, NCF1, NCF2, or NCF4 gene mutations, the condition is inherited in an autosomal recessive pattern.
| Descriptor ID |
D006105
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| MeSH Number(s) |
C15.378.553.774.535 C16.320.322.233 C20.673.774.535
|
| Concept/Terms |
Granulomatous Disease, Chronic- Granulomatous Disease, Chronic
- Chronic Granulomatous Diseases
- Granulomatous Diseases, Chronic
- Chronic Granulomatous Disease
Granulomatous Disease, Chronic, X-Linked- Granulomatous Disease, Chronic, X-Linked
- Cytochrome B-Negative Granulomatous Disease, Chronic, X-Linked
- X-Linked Chronic Granulomatous Disease
- X Linked Chronic Granulomatous Disease
- Granulomatous Disease, Chronic, X-Linked, Variant
- Chronic Granulomatous Disease, Atypical
- Chronic Granulomatous Disease, X-Linked
- Chronic Granulomatous Disease, X Linked
- Cytochrome B-Positive Granulomatous Disease, Chronic, X-Linked
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Below are MeSH descriptors whose meaning is more general than "Granulomatous Disease, Chronic".
Below are MeSH descriptors whose meaning is more specific than "Granulomatous Disease, Chronic".
This graph shows the total number of publications written about "Granulomatous Disease, Chronic" by people in this website by year, and whether "Granulomatous Disease, Chronic" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 |
| 2013 | 1 | 1 | 2 |
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Below are the most recent publications written about "Granulomatous Disease, Chronic" by people in Profiles.
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Buckner CM, Moir S, Kardava L, Ho J, Santich BH, Kim LJ, Funk EK, Nelson AK, Winckler B, Chairez CL, Theobald-Whiting NL, Anaya-O'Brien S, Alimchandani M, Quezado MM, Yao MD, Kovacs JA, Chun TW, Fauci AS, Malech HL, De Ravin SS. CXCR4/IgG-expressing plasma cells are associated with human gastrointestinal tissue inflammation. J Allergy Clin Immunol. 2014 Jun; 133(6):1676-85.e5.
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Alimchandani M, Lai JP, Aung PP, Khangura S, Kamal N, Gallin JI, Holland SM, Malech HL, Heller T, Miettinen M, Quezado MM. Gastrointestinal histopathology in chronic granulomatous disease: a study of 87 patients. Am J Surg Pathol. 2013 Sep; 37(9):1365-72.
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Lublin M, Bartlett DL, Danforth DN, Kauffman H, Gallin JI, Malech HL, Shawker T, Choyke P, Kleiner DE, Schwartzentruber DJ, Chang R, DeCarlo ES, Holland SM. Hepatic abscess in patients with chronic granulomatous disease. Ann Surg. 2002 Mar; 235(3):383-91.