Histiocytosis, Langerhans-Cell
"Histiocytosis, Langerhans-Cell" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of disorders resulting from the abnormal proliferation of and tissue infiltration by LANGERHANS CELLS which can be detected by their characteristic Birbeck granules (X bodies), or by monoclonal antibody staining for their surface CD1 ANTIGENS. Langerhans-cell granulomatosis can involve a single organ, or can be a systemic disorder.
Descriptor ID |
D006646
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MeSH Number(s) |
C08.381.483.375 C15.604.250.400
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Concept/Terms |
Histiocytosis, Langerhans-Cell- Histiocytosis, Langerhans-Cell
- Histiocytosis, Langerhans Cell
- Hand-Schueller-Christian Syndrome
- Hand Schueller Christian Syndrome
- Syndrome, Hand-Schueller-Christian
- Hand-Schüller-Christian Disease
- Disease, Hand-Schüller-Christian
- Hand Schüller Christian Disease
- Hand-Schüller-Christian Syndrome
- Hand Schüller Christian Syndrome
- Syndrome, Hand-Schüller-Christian
- Histiocytosis X
- Histiocytosis, Generalized
- Generalized Histiocytoses
- Generalized Histiocytosis
- Histiocytoses, Generalized
- Histiocytosis-X
- Langerhans Cell Histiocytosis
- Cell Histiocytoses, Langerhans
- Cell Histiocytosis, Langerhans
- Histiocytoses, Langerhans Cell
- Langerhans Cell Histiocytoses
- Langerhans-Cell Granulomatosis
- Granulomatosis, Langerhans-Cell
- Langerhans-Cell Histiocytosis
- Letterer-Siwe Disease
- Disease, Letterer-Siwe
- Letterer Siwe Disease
- Non-Lipid Reticuloendotheliosis
- Non Lipid Reticuloendotheliosis
- Non-Lipid Reticuloendothelioses
- Reticuloendothelioses, Non-Lipid
- Reticuloendotheliosis, Non-Lipid
- Schueller-Christian Disease
- Disease, Schueller-Christian
- Schueller Christian Disease
- Systemic Aleukemic Reticuloendotheliosis
- Aleukemic Reticuloendothelioses, Systemic
- Aleukemic Reticuloendotheliosis, Systemic
- Reticuloendothelioses, Systemic Aleukemic
- Reticuloendotheliosis, Systemic Aleukemic
- Systemic Aleukemic Reticuloendothelioses
- Type 2 Histiocytosis
- Histiocytoses, Type 2
- Histiocytosis, Type 2
- Type 2 Histiocytoses
- Langerhans Cell Granulomatosis
- Cell Granulomatoses, Langerhans
- Cell Granulomatosis, Langerhans
- Granulomatoses, Langerhans Cell
- Granulomatosis, Langerhans Cell
- Langerhans Cell Granulomatoses
- Hand-Schueller-Christian Disease
- Disease, Hand-Schueller-Christian
- Hand Schueller Christian Disease
Pulmonary Histiocytosis X- Pulmonary Histiocytosis X
- Histiocytosis X, Pulmonary
- Pulmonary Langerhans Cell Granulomatosis
- Langerhans Cell Granulomatosis, Pulmonary
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Below are MeSH descriptors whose meaning is more general than "Histiocytosis, Langerhans-Cell".
Below are MeSH descriptors whose meaning is more specific than "Histiocytosis, Langerhans-Cell".
This graph shows the total number of publications written about "Histiocytosis, Langerhans-Cell" by people in this website by year, and whether "Histiocytosis, Langerhans-Cell" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2003 | 1 | 0 | 1 |
2004 | 1 | 0 | 1 |
2006 | 1 | 0 | 1 |
2007 | 1 | 0 | 1 |
2010 | 3 | 0 | 3 |
2013 | 0 | 1 | 1 |
2015 | 2 | 0 | 2 |
2019 | 1 | 0 | 1 |
2020 | 1 | 0 | 1 |
2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Histiocytosis, Langerhans-Cell" by people in Profiles.
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Milman T, Eiger-Moscovich M, Henry RK, Ida CM, Ruben M, Shields CL, Lally SE, Penne RB, Stefanyszyn MA, Bilyk JR, Rapuano CJ, Rabinowitz M, Eagle RC. Cyclin D1 Expression and Molecular Genetic Findings in Periocular Histiocytoses and Neoplasms of Macrophage-Dendritic Cell Lineage. Am J Ophthalmol. 2022 10; 242:36-51.
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Salama HA, Jazieh AR, Alhejazi AY, Absi A, Alshieban S, Alzahrani M, Alaskar A, Gmati G, Damlaj M, Abuelgasim KA, Alghamdi A, Alahmari B, Almugairi A, Alzahrani H, Bazarbachi A, Musa MOH, Goyal G. Highlights of the Management of Adult Histiocytic Disorders: Langerhans Cell Histiocytosis, Erdheim-Chester Disease, Rosai-Dorfman Disease, and Hemophagocytic Lymphohistiocytosis. Clin Lymphoma Myeloma Leuk. 2021 01; 21(1):e66-e75.
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Peck T, Bagg A, Zhang X, Armstrong B, Eagle RC, Milman T. Isolated Langerhans Cell Histiocytosis of the Lacrimal Gland in Conjunction With Mucosa-Associated Lymphoid Tissue Lymphoma and Elevated IgG4 Plasma Cells. Ophthalmic Plast Reconstr Surg. 2019 Jul/Aug; 35(4):e92-e94.
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Thomas G, Dixon RK, Zimrin A, Papadimitriou J, Shah NG. Pulmonary Langerhans cell histiocytosis with systemic features. Am J Med. 2015 Oct; 128(10):e7-9.
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Picarsic J, Egeler RM, Chikwava K, Patterson K, Jaffe R. Histologic patterns of thymic involvement in Langerhans cell proliferations: a clinicopathologic study and review of the literature. Pediatr Dev Pathol. 2015 Mar-Apr; 18(2):127-38.
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Willard KJ, Cappel MA, Kozin SH, Abzug JM. Congenital and infantile benign skin lesions affecting the hand and upper extremity, part 2: nonvascular neoplasms. J Hand Surg Am. 2013 Nov; 38(11):2284-92.
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Shields CL, Hogarty MD, Kligman BE, Christian C, Ehya H, Shields JA. Langerhans cell histiocytosis of the uvea with neovascular glaucoma: diagnosis by fine-needle aspiration biopsy and management with intraocular bevacizumab and brachytherapy. J AAPOS. 2010 Dec; 14(6):534-7.
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Todd WU, Drabick JJ, Benninghoff MG, Frauenhoffer EE, Zander DS. Pulmonary crystal-storing histiocytosis diagnosed by computed tomography-guided fine-needle aspiration. Diagn Cytopathol. 2010 Apr; 38(4):274-8.
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Shah UK, Nicholas B, Hurd J, Nesargi S, Corao-Uribe D. Case report: Langerhans cell histiocytosis presenting as massive cervical adenopathy and retropharyngeal thickening: importance of chest radiography and coordinated airway and anesthetic management. Pediatr Emerg Care. 2010 Feb; 26(2):139-42.
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Chikwava KR, Hunt JL, Mantha GS, Murphy JE, Jaffe R. Analysis of loss of heterozygosity in single-system and multisystem Langerhans' cell histiocytosis. Pediatr Dev Pathol. 2007 Jan-Feb; 10(1):18-24.