Hypoglossal Nerve

"Hypoglossal Nerve" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The 12th cranial nerve. The hypoglossal nerve originates in the hypoglossal nucleus of the medulla and supplies motor innervation to all of the muscles of the tongue except the palatoglossus (which is supplied by the vagus). This nerve also contains proprioceptive afferents from the tongue muscles.

Descriptor ID	D007002
MeSH Number(s)	A08.800.800.120.330
Concept/Terms	Hypoglossal Nerve Hypoglossal Nerve Hypoglossal Nerves Nerve, Hypoglossal Nerves, Hypoglossal Twelfth Cranial Nerve Cranial Nerve, Twelfth Cranial Nerves, Twelfth Nerve, Twelfth Cranial Nerves, Twelfth Cranial Twelfth Cranial Nerves Nerve XII Nerve XIIs XII, Nerve XIIs, Nerve Cranial Nerve XII Cranial Nerve XIIs Nerve XII, Cranial Nerve XIIs, Cranial Nervus Hypoglossus Hypoglossus, Nervus

Below are MeSH descriptors whose meaning is more general than "Hypoglossal Nerve".

Anatomy [A]
Nervous System [A08]
Peripheral Nervous System [A08.800]
Peripheral Nerves [A08.800.800]
Cranial Nerves [A08.800.800.120]
Hypoglossal Nerve [A08.800.800.120.330]

Below are MeSH descriptors whose meaning is related to "Hypoglossal Nerve".

Below are MeSH descriptors whose meaning is more specific than "Hypoglossal Nerve".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Hypoglossal Nerve" by people in this website by year, and whether "Hypoglossal Nerve" was a major or minor topic of these publications.

Bar chart showing 26 publications over 10 distinct years, with a maximum of 6 publications in 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2003	0	1	1
2016	1	0	1
2017	1	0	1
2018	0	4	4
2019	2	1	3
2020	1	0	1
2021	2	4	6
2022	1	2	3
2024	4	1	5
2025	1	0	1

Below are the most recent publications written about "Hypoglossal Nerve" by people in Profiles.

Kaffenberger TM, Sina EM, Hambach B, Kaki P, Fuleihan A, Boon M, Huntley C. How we measure hypoglossal nerve stimulator outcome matters: titration vs single amplitude efficacy sleep studies. J Clin Sleep Med. 2025 Jan 01; 21(1):47-53.

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Corr A, Sina EM, Creighton E, Bautista N, Chandna M, Boon M, Huntley C. Using Postactivation Adjustment as a Marker for Inferior Outcomes in Hypoglossal Nerve Stimulator Patients. Otolaryngol Head Neck Surg. 2025 Mar; 172(3):1063-1068.

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Kaki PC, Molin N, Goldfarb JA, Kaffenberger TM, Creighton E, Boon M, Huntley C. Relationship of Modified Sleep Apnea Severity Index and HGNS Efficacy and Adherence in OSA Patients. Laryngoscope. 2025 Mar; 135(3):1212-1217.

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Moroco AE, Wei Z, Byrd I, Rasmussen A, Chio EG, Soose RJ, Huyett P, Steffen A, Heiser C, Boon MS, Huntley CT. Device-related outcomes following hypoglossal nerve stimulator implantation. J Clin Sleep Med. 2024 Sep 01; 20(9):1497-1503.

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Mandloi S, Garg N, Naimi B, Shah R, Kaki P, Alnemri A, Duffy A, Zhan T, Kaffenberger TM, Boon MS, Huntley CT. Transoral Robotic Surgery Versus Hypoglossal Nerve Stimulation for OSA: A Cost Analysis Study. Laryngoscope. 2025 Jan; 135(1):457-462.

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Dedhia RC, Bliwise DL, Quyyumi AA, Thaler ER, Boon MS, Huntley CT, Seay EG, Tangutur A, Strollo PJ, Gurel N, Keenan BT. Hypoglossal Nerve Stimulation and Cardiovascular Outcomes for Patients With Obstructive Sleep Apnea: A Randomized Clinical Trial. JAMA Otolaryngol Head Neck Surg. 2024 01 01; 150(1):39-48.

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Cheong CS, Dedhia RC, Seay EG, Jara SM, Mora JI, Thaler ER, Schwartz AR. Enhanced drug-induced sleep endoscopy: Distinguishing central from obstructive apnea. Laryngoscope. 2023 03; 133(3):706-708.

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Renslo B, Hobelmann K, Sagalow ES, Ananth A, Boon M, Huntley C. Palatal Coupling Maneuvers Do Not Predict Hypoglossal Nerve Stimulator Treatment Efficacy. Laryngoscope. 2023 02; 133(2):431-436.

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Sagalow ES, Rodin J, Estephan L, Jackson J, Crippen M, Boon M, Huntley C. Two-Incision Approach for Hypoglossal Nerve Stimulator Placement: A Single Institution Assessment. Laryngoscope. 2022 08; 132(8):1687-1691.

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Suurna MV, Jacobowitz O, Chang J, Koutsourelakis I, Smith D, Alkan U, D'Agostino M, Boon M, Heiser C, Hoff P, Huntley C, Kent D, Kominsky A, Lewis R, Maurer JT, Ravesloot MJ, Soose R, Steffen A, Weaver EM, Williams AM, Woodson T, Yaremchuk K, Ishman SL. Improving outcomes of hypoglossal nerve stimulation therapy: current practice, future directions, and research gaps. Proceedings of the 2019 International Sleep Surgery Society Research Forum. J Clin Sleep Med. 2021 12 01; 17(12):2477-2487.

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