Keratan Sulfate

"Keratan Sulfate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A sulfated mucopolysaccharide initially isolated from bovine cornea. At least two types are known. Type I, found mostly in the cornea, contains D-galactose and D-glucosamine-6-O-sulfate as the repeating unit; type II, found in skeletal tissues, contains D-galactose and D-galactosamine-6-O-sulfate as the repeating unit.

Descriptor ID	D007632
MeSH Number(s)	D09.698.373.550
Concept/Terms	Keratan Sulfate Keratan Sulfate Sulfate, Keratan Keratosulfate

Below are MeSH descriptors whose meaning is more general than "Keratan Sulfate".

Chemicals and Drugs [D]
Carbohydrates [D09]
Polysaccharides [D09.698]
Glycosaminoglycans [D09.698.373]
Keratan Sulfate [D09.698.373.550]

Below are MeSH descriptors whose meaning is related to "Keratan Sulfate".

Below are MeSH descriptors whose meaning is more specific than "Keratan Sulfate".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Keratan Sulfate" by people in this website by year, and whether "Keratan Sulfate" was a major or minor topic of these publications.

Bar chart showing 24 publications over 19 distinct years, with a maximum of 2 publications in 2004 and 2007 and 2013 and 2018 and 2023

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2000	1	0	1
2003	1	0	1
2004	1	1	2
2005	0	1	1
2006	1	0	1
2007	1	1	2
2008	0	1	1
2009	0	1	1
2010	1	0	1
2011	0	1	1
2012	0	1	1
2013	1	1	2
2014	0	1	1
2016	0	1	1
2018	0	2	2
2019	0	1	1
2020	0	1	1
2022	0	1	1
2023	0	2	2

Below are the most recent publications written about "Keratan Sulfate" by people in Profiles.

Leal AF, Alm?ciga-D?az CJ, Tomatsu S. Mucopolysaccharidosis IVA: Current Disease Models and Drawbacks. Int J Mol Sci. 2023 Nov 09; 24(22).

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Rintz E, Herre?o-Pach?n AM, Celik B, Nidhi F, Khan S, Benincore-Fl?rez E, Tomatsu S. Bone Growth Induction in Mucopolysaccharidosis IVA Mouse. Int J Mol Sci. 2023 Jun 08; 24(12).

View in: PubMed
Mitchell JJ, Burton BK, Bober MB, Campeau PM, Cohen S, Dosenovic S, Ellaway C, Bhattacharya K, Guffon N, Hinds D, Lail A, Lin SP, Magner M, Raiman J, Schwartz-Sagi L, Stepien KM. Findings from the Morquio A Registry Study (MARS) after 6 years: Long-term outcomes of MPS IVA patients treated with elosulfase alfa. Mol Genet Metab. 2022 Sep-Oct; 137(1-2):164-172.

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Sawamoto K, ?lvarez Gonz?lez JV, Piechnik M, Otero FJ, Couce ML, Suzuki Y, Tomatsu S. Mucopolysaccharidosis IVA: Diagnosis, Treatment, and Management. Int J Mol Sci. 2020 Feb 23; 21(4).

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Rodr?guez-L?pez A, Pimentel-Vera LN, Espejo-Mojica AJ, Van Hecke A, Tiels P, Tomatsu S, Callewaert N, Alm?ciga-D?az CJ. Characterization of Human Recombinant N-Acetylgalactosamine-6-Sulfate Sulfatase Produced in Pichia pastoris as Potential Enzyme for Mucopolysaccharidosis IVA Treatment. J Pharm Sci. 2019 08; 108(8):2534-2541.

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Khan SA, Mason RW, Giugliani R, Orii K, Fukao T, Suzuki Y, Yamaguchi S, Kobayashi H, Orii T, Tomatsu S. Glycosaminoglycans analysis in blood and urine of patients with mucopolysaccharidosis. Mol Genet Metab. 2018 09; 125(1-2):44-52.

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Peracha H, Sawamoto K, Averill L, Kecskemethy H, Theroux M, Thacker M, Nagao K, Pizarro C, Mackenzie W, Kobayashi H, Yamaguchi S, Suzuki Y, Orii K, Orii T, Fukao T, Tomatsu S. Molecular genetics and metabolism, special edition: Diagnosis, diagnosis and prognosis of Mucopolysaccharidosis IVA. Mol Genet Metab. 2018 09; 125(1-2):18-37.

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Kubaski F, Suzuki Y, Orii K, Giugliani R, Church HJ, Mason RW, Dung VC, Ngoc CT, Yamaguchi S, Kobayashi H, Girisha KM, Fukao T, Orii T, Tomatsu S. Glycosaminoglycan levels in dried blood spots of patients with mucopolysaccharidoses and mucolipidoses. Mol Genet Metab. 2017 03; 120(3):247-254.

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Tomatsu S, Monta?o AM, Oikawa H, Dung VC, Hashimoto A, Oguma T, Guti?rrez ML, Takahashi T, Shimada T, Orii T, Sly WS. Enzyme replacement therapy in newborn mucopolysaccharidosis IVA mice: early treatment rescues bone lesions? Mol Genet Metab. 2015 Feb; 114(2):195-202.

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Dung VC, Tomatsu S, Monta?o AM, Gottesman G, Bober MB, Mackenzie W, Maeda M, Mitchell GA, Suzuki Y, Orii T. Mucopolysaccharidosis IVA: correlation between genotype, phenotype and keratan sulfate levels. Mol Genet Metab. 2013 Sep-Oct; 110(1-2):129-38.

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