Lipopolysaccharides

"Lipopolysaccharides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)

Descriptor ID	D008070
MeSH Number(s)	D09.400.500 D09.698.718.450 D10.494 D23.050.161.616.525 D23.946.123.329.500
Concept/Terms	Lipopolysaccharides Lipopolysaccharides Lipoglycans

Below are MeSH descriptors whose meaning is more general than "Lipopolysaccharides".

Chemicals and Drugs [D]
Carbohydrates [D09]
Glycoconjugates [D09.400]
Lipopolysaccharides [D09.400.500]
Polysaccharides [D09.698]
Polysaccharides, Bacterial [D09.698.718]
Lipopolysaccharides [D09.698.718.450]
Lipids [D10]
Lipopolysaccharides [D10.494]
Biological Factors [D23]
Antigens [D23.050]
Antigens, Bacterial [D23.050.161]
Polysaccharides, Bacterial [D23.050.161.616]
Lipopolysaccharides [D23.050.161.616.525]
Toxins, Biological [D23.946]
Bacterial Toxins [D23.946.123]
Endotoxins [D23.946.123.329]
Lipopolysaccharides [D23.946.123.329.500]

Below are MeSH descriptors whose meaning is related to "Lipopolysaccharides".

Below are MeSH descriptors whose meaning is more specific than "Lipopolysaccharides".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Lipopolysaccharides" by people in this website by year, and whether "Lipopolysaccharides" was a major or minor topic of these publications.

Bar chart showing 51 publications over 15 distinct years, with a maximum of 10 publications in 2006

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	1	2
2003	5	3	8
2004	2	2	4
2005	0	3	3
2006	3	7	10
2007	1	1	2
2008	0	1	1
2009	0	1	1
2010	5	2	7
2011	2	3	5
2012	1	0	1
2015	0	2	2
2016	0	2	2
2017	0	2	2
2021	0	1	1

Below are the most recent publications written about "Lipopolysaccharides" by people in Profiles.

Mayes-Hopfinger L, Enache A, Xie J, Huang CL, Köchl R, Tybulewicz VLJ, Fernandes-Alnemri T, Alnemri ES. Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis. Nat Commun. 2021 07 27; 12(1):4546.

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Poole LG, Massey VL, Siow DL, Torres-Gonzáles E, Warner NL, Luyendyk JP, Ritzenthaler JD, Roman J, Arteel GE. Plasminogen Activator Inhibitor-1 Is Critical in Alcohol-Enhanced Acute Lung Injury in Mice. Am J Respir Cell Mol Biol. 2017 09; 57(3):315-323.

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Johnson ZI, Doolittle AC, Snuggs JW, Shapiro IM, Le Maitre CL, Risbud MV. TNF-a promotes nuclear enrichment of the transcription factor TonEBP/NFAT5 to selectively control inflammatory but not osmoregulatory responses in nucleus pulposus cells. J Biol Chem. 2017 10 20; 292(42):17561-17575.

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Zhou H, Harberts E, Fishelevich R, Gaspari AA. TLR4 acts as a death receptor for ultraviolet radiation (UVR) through IRAK-independent and FADD-dependent pathway in macrophages. Exp Dermatol. 2016 12; 25(12):949-955.

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Palmieri EM, Menga A, Lebrun A, Hooper DC, Butterfield DA, Mazzone M, Castegna A. Blockade of Glutamine Synthetase Enhances Inflammatory Response in Microglial Cells. Antioxid Redox Signal. 2017 03 10; 26(8):351-363.

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Massey VL, Poole LG, Siow DL, Torres E, Warner NL, Schmidt RH, Ritzenthaler JD, Roman J, Arteel GE. Chronic Alcohol Exposure Enhances Lipopolysaccharide-Induced Lung Injury in Mice: Potential Role of Systemic Tumor Necrosis Factor-Alpha. Alcohol Clin Exp Res. 2015 Oct; 39(10):1978-88.

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Jin S, Merchant ML, Ritzenthaler JD, McLeish KR, Lederer ED, Torres-Gonzalez E, Fraig M, Barati MT, Lentsch AB, Roman J, Klein JB, Rane MJ. Baclofen, a GABABR agonist, ameliorates immune-complex mediated acute lung injury by modulating pro-inflammatory mediators. PLoS One. 2015; 10(4):e0121637.

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Zhou F, Ciric B, Li H, Yan Y, Li K, Cullimore M, Lauretti E, Gonnella P, Zhang GX, Rostami A. IL-10 deficiency blocks the ability of LPS to regulate expression of tolerance-related molecules on dendritic cells. Eur J Immunol. 2012 Jun; 42(6):1449-58.

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Konter JM, Parker JL, Baez E, Li SZ, Ranscht B, Denzel M, Little FF, Nakamura K, Ouchi N, Fine A, Walsh K, Summer RS. Adiponectin attenuates lipopolysaccharide-induced acute lung injury through suppression of endothelial cell activation. J Immunol. 2012 Jan 15; 188(2):854-63.

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Terai M, Eto M, Young GD, Berd D, Mastrangelo MJ, Tamura Y, Harigaya K, Sato T. Interleukin 6 mediates production of interleukin 10 in metastatic melanoma. Cancer Immunol Immunother. 2012 Feb; 61(2):145-55.

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