"Maleimides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Derivatives of maleimide (the structural formula H2C2(CO)2NH) containing a pyrroledione ring where the hydrogen atom of the NH group is replaced with aliphatic or aromatic groups.
| Descriptor ID |
D008301
|
| MeSH Number(s) |
D02.241.081.337.502.524 D02.478.440 D03.383.129.578.399
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Maleimides".
Below are MeSH descriptors whose meaning is more specific than "Maleimides".
This graph shows the total number of publications written about "Maleimides" by people in this website by year, and whether "Maleimides" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 2 | 2 |
| 2008 | 1 | 1 | 2 |
| 2011 | 1 | 1 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 2 | 2 | 4 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Maleimides" by people in Profiles.
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Yang DB, Zhang T, Blum JE, Kloxin CJ, Pochan DJ, Saven JG. Complementary Peptide Interactions Support the Ultra-Rigidity of Polymers of De Novo Designed Click-Functionalized Bundlemers. J Phys Chem B. 2025 Feb 06; 129(5):1462-1474.
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Wu H, LeValley PJ, Luo T, Kloxin AM, Kiick KL. Manipulation of Glutathione-Mediated Degradation of Thiol-Maleimide Conjugates. Bioconjug Chem. 2018 11 21; 29(11):3595-3605.
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Kharkar PM, Scott RA, Olney LP, LeValley PJ, Maverakis E, Kiick KL, Kloxin AM. Controlling the Release of Small, Bioactive Proteins via Dual Mechanisms with Therapeutic Potential. Adv Healthc Mater. 2017 Dec; 6(24).
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Ugolkov A, Gaisina I, Zhang JS, Billadeau DD, White K, Kozikowski A, Jain S, Cristofanilli M, Giles F, O'Halloran T, Cryns VL, Mazar AP. GSK-3 inhibition overcomes chemoresistance in human breast cancer. Cancer Lett. 2016 10 01; 380(2):384-392.
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Hummler SC, Rong M, Chen S, Hehre D, Alapati D, Wu S. Targeting glycogen synthase kinase-3? to prevent hyperoxia-induced lung injury in neonatal rats. Am J Respir Cell Mol Biol. 2013 May; 48(5):578-88.
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Zhou J, Freeman TA, Ahmad F, Shang X, Mangano E, Gao E, Farber J, Wang Y, Ma XL, Woodgett J, Vagnozzi RJ, Lal H, Force T. GSK-3a is a central regulator of age-related pathologies in mice. J Clin Invest. 2013 Apr; 123(4):1821-32.
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Singh J, Rattan S. Role of PKC and RhoA/ROCK pathways in the spontaneous phasic activity in the rectal smooth muscle. Am J Physiol Gastrointest Liver Physiol. 2013 Apr 15; 304(8):G723-31.
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Sapra A, Thorpe C. An arsenical-maleimide for the generation of new targeted biochemical reagents. J Am Chem Soc. 2013 Feb 20; 135(7):2415-8.
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Singh J, Rattan S. Bioengineered human IAS reconstructs with functional and molecular properties similar to intact IAS. Am J Physiol Gastrointest Liver Physiol. 2012 Sep 15; 303(6):G713-22.
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Ritter DM, Ho C, O'Leary ME, Covarrubias M. Modulation of Kv3.4 channel N-type inactivation by protein kinase C shapes the action potential in dorsal root ganglion neurons. J Physiol. 2012 Jan 01; 590(1):145-61.