"Manganese" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
| Descriptor ID |
D008345
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| MeSH Number(s) |
D01.268.556.484 D01.268.956.374 D01.552.544.484
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Manganese".
Below are MeSH descriptors whose meaning is more specific than "Manganese".
This graph shows the total number of publications written about "Manganese" by people in this website by year, and whether "Manganese" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 1 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2006 | 3 | 0 | 3 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 1 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Manganese" by people in Profiles.
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Kent T, Mateos-Gomez PA, Sfeir A, Pomerantz RT. Polymerase ? is a robust terminal transferase that oscillates between three different mechanisms during end-joining. Elife. 2016 06 17; 5.
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Clark HL, Jhingran A, Sun Y, Vareechon C, de Jesus Carrion S, Skaar EP, Chazin WJ, Calera JA, Hohl TM, Pearlman E. Zinc and Manganese Chelation by Neutrophil S100A8/A9 (Calprotectin) Limits Extracellular Aspergillus fumigatus Hyphal Growth and Corneal Infection. J Immunol. 2016 Jan 01; 196(1):336-44.
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Tuchinda P, Liu Y, Tammaro A, Harberts E, Goldner R, Gaspari AA. Resolution of occupational dermatitis related to manganese exposures. Dermatitis. 2014 Sep-Oct; 25(5):280-1.
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Davis RM, Viglianti BL, Yarmolenko P, Park JY, Stauffer P, Needham D, Dewhirst MW. A method to convert MRI images of temperature change into images of absolute temperature in solid tumours. Int J Hyperthermia. 2013 Sep; 29(6):569-81.
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Verina T, Kiihl SF, Schneider JS, Guilarte TR. Manganese exposure induces microglia activation and dystrophy in the substantia nigra of non-human primates. Neurotoxicology. 2011 Mar; 32(2):215-26.
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Selvakumar P, Lakshmikuttyamma A, Sharma RK. Biochemical characterization of bovine brain myristoyl-CoA:protein N-myristoyltransferase type 2. J Biomed Biotechnol. 2009; 2009:907614.
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Guilarte TR, Burton NC, McGlothan JL, Verina T, Zhou Y, Alexander M, Pham L, Griswold M, Wong DF, Syversen T, Schneider JS. Impairment of nigrostriatal dopamine neurotransmission by manganese is mediated by pre-synaptic mechanism(s): implications to manganese-induced parkinsonism. J Neurochem. 2008 Dec; 107(5):1236-47.
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Guilarte TR, Burton NC, Verina T, Prabhu VV, Becker KG, Syversen T, Schneider JS. Increased APLP1 expression and neurodegeneration in the frontal cortex of manganese-exposed non-human primates. J Neurochem. 2008 Jun; 105(5):1948-59.
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Aschner M, Guilarte TR, Schneider JS, Zheng W. Manganese: recent advances in understanding its transport and neurotoxicity. Toxicol Appl Pharmacol. 2007 Jun 1; 221(2):131-47.
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Guilarte TR, McGlothan JL, Degaonkar M, Chen MK, Barker PB, Syversen T, Schneider JS. Evidence for cortical dysfunction and widespread manganese accumulation in the nonhuman primate brain following chronic manganese exposure: a 1H-MRS and MRI study. Toxicol Sci. 2006 Dec; 94(2):351-8.