Metformin

"Metformin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A biguanide hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary modification. Metformin improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. (From Martindale, The Extra Pharmacopoeia, 30th ed, p289)

Descriptor ID	D008687
MeSH Number(s)	D02.078.370.141.450
Concept/Terms	Metformin Metformin Dimethylbiguanidine Dimethylguanylguanidine Glucophage Glucophage Metformin Hydrochloride Metformin Hydrochloride Hydrochloride, Metformin Metformin HCl HCl, Metformin

Below are MeSH descriptors whose meaning is more general than "Metformin".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Amidines [D02.078]
Guanidines [D02.078.370]
Biguanides [D02.078.370.141]
Metformin [D02.078.370.141.450]

Below are MeSH descriptors whose meaning is related to "Metformin".

Below are MeSH descriptors whose meaning is more specific than "Metformin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Metformin" by people in this website by year, and whether "Metformin" was a major or minor topic of these publications.

Bar chart showing 39 publications over 17 distinct years, with a maximum of 4 publications in 2011 and 2017 and 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2004	1	0	1
2006	1	1	2
2007	3	0	3
2008	2	0	2
2009	0	3	3
2010	1	2	3
2011	3	1	4
2012	2	1	3
2013	2	0	2
2014	0	1	1
2015	3	0	3
2017	0	4	4
2020	1	0	1
2021	2	2	4
2022	1	0	1
2023	1	0	1
2024	1	0	1

Below are the most recent publications written about "Metformin" by people in Profiles.

Venkatesh KK, MacPherson C, Clifton RG, Powe CE, Bartholomew A, Gregory D, Trinh A, McAlearney AS, Fiechtner LG, Catalano P, Rice D, Cross S, Kutay H, Gabbe S, Grobman WA, Costantine MM, Battarbee AN, Boggess K, Katukuri V, Eichelberger K, Esakoff T, Feghali MN, Harper L, Kaimal A, Kole-White M, Mendez-Figueroa H, Mlynarczyk M, Sciscione A, Shook L, Sobhani NC, Stamilio DM, Werner E, Wiegand S, Zera CA, Zork NM, Saade G, Landon MB. Comparative effectiveness trial of metformin versus insulin for the treatment of gestational diabetes in the USA: clinical trial protocol for the multicentre DECIDE study. BMJ Open. 2024 Sep 24; 14(9):e091176.

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Wai KM, Saroj N, Boucher N, Aggarwal N, Ho AC, Rahimy E. Evaluating the Effect of Hypoglycemic Agents on Diabetic Retinopathy Progression. Ophthalmic Surg Lasers Imaging Retina. 2023 Mar; 54(3):158-165.

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Cunningham A, Li E, Silverio A, Mills G, Han J, Waters A. Patient and provider prediabetes knowledge, attitudes, and behavior in a large urban family medicine practice. Ann Fam Med. 2022 04 01; (20 Suppl 1).

View in: PubMed
Seikrit C, Lausberg E, Buhl EM, Gaspar R, Tabi T, Heffer M, Ducza E, Sztojkov-Ivanov A, Seres AB, Szucs K, Ivic V, Floege J, Vari SG, Boor P, Klinkhammer BM. A Hypercaloric Diet Induces Early Podocyte Damage in Aged, Non-Diabetic Rats. Cell Physiol Biochem. 2021 Dec 23; 55(S4):96-112.

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Kent DM, Nelson J, Pittas A, Colangelo F, Koenig C, van Klaveren D, Ciemins E, Cuddeback J. An Electronic Health Record-Compatible Model to Predict Personalized Treatment Effects From the Diabetes Prevention Program: A Cross-Evidence Synthesis Approach Using Clinical Trial and Real-World Data. Mayo Clin Proc. 2022 04; 97(4):703-715.

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Marek-Iannucci S, Ozdemir AB, Moreira D, Gomez AC, Lane M, Porritt RA, Lee Y, Shimada K, Abe M, Stotland A, Zemmour D, Parker S, Sanchez-Lopez E, Van Eyk J, Gottlieb RA, Fishbein MC, Karin M, Crother TR, Rivas MN, Arditi M. Autophagy-mitophagy induction attenuates cardiovascular inflammation in a murine model of Kawasaki disease vasculitis. JCI Insight. 2021 09 22; 6(18).

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Walker K, Decherney AH, Saunders R. Menstrual Dysfunction in PCOS. Clin Obstet Gynecol. 2021 03 01; 64(1):119-125.

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Doyle-Delgado K, Chamberlain JJ, Shubrook JH, Skolnik N, Trujillo J. Pharmacologic Approaches to Glycemic Treatment of Type 2 Diabetes: Synopsis of the 2020 American Diabetes Association's Standards of Medical Care in Diabetes Clinical Guideline. Ann Intern Med. 2020 11 17; 173(10):813-821.

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Chamberlain JJ, Kalyani RR, Leal S, Rhinehart AS, Shubrook JH, Skolnik N, Herman WH. Treatment of Type 1 Diabetes: Synopsis of the 2017 American Diabetes Association Standards of Medical Care in Diabetes. Ann Intern Med. 2017 Oct 03; 167(7):493-498.

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Skolnik N, Jaffa FM, Kalyani RR, Johnson E, Shubrook JH. Reducing CV risk in diabetes: An ADA update. J Fam Pract. 2017 May; 66(5):300-308.

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