Below are the most recent publications written about "Microsomes, Liver" by people in Profiles.
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Davydov DR, Davydova NY, Rodgers JT, Rushmore TH, Jones JP. Toward a systems approach to the human cytochrome P450 ensemble: interactions between CYP2D6 and CYP2E1 and their functional consequences. Biochem J. 2017 10 10; 474(20):3523-3542.
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Salvino JM, Srikanth YVV, Lou R, Oyer HM, Chen N, Kim FJ. Novel small molecule guanidine Sigma1 inhibitors for advanced prostate cancer. Bioorg Med Chem Lett. 2017 05 15; 27(10):2216-2220.
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Anyatonwu G, Khan MT, Schug ZT, da Fonseca PC, Morris EP, Joseph SK. Calcium-dependent conformational changes in inositol trisphosphate receptors. J Biol Chem. 2010 Aug 6; 285(32):25085-93.
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Childers WE, Havran LM, Asselin M, Bicksler JJ, Chong DC, Grosu GT, Shen Z, Abou-Gharbia MA, Bach AC, Harrison BL, Kagan N, Kleintop T, Magolda R, Marathias V, Robichaud AJ, Sabb AL, Zhang MY, Andree TH, Aschmies SH, Beyer C, Comery TA, Day M, Grauer SM, Hughes ZA, Rosenzweig-Lipson S, Platt B, Pulicicchio C, Smith DE, Sukoff-Rizzo SJ, Sullivan KM, Adedoyin A, Huselton C, Hirst WD. The synthesis and biological evaluation of quinolyl-piperazinyl piperidines as potent serotonin 5-HT1A antagonists. J Med Chem. 2010 May 27; 53(10):4066-84.
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Cole DC, Stock JR, Lennox WJ, Bernotas RC, Ellingboe JW, Boikess S, Coupet J, Smith DL, Leung L, Zhang GM, Feng X, Kelly MF, Galante R, Huang P, Dawson LA, Marquis K, Rosenzweig-Lipson S, Beyer CE, Schechter LE. Discovery of N1-(6-chloroimidazo[2,1-b][1,3]thiazole-5-sulfonyl)tryptamine as a potent, selective, and orally active 5-HT(6) receptor agonist. J Med Chem. 2007 Nov 15; 50(23):5535-8.
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Saulnier MG, Balasubramanian BN, Long BH, Frennesson DB, Ruediger E, Zimmermann K, Eummer JT, St Laurent DR, Stoffan KM, Naidu BN, Mahler M, Beaulieu F, Bachand C, Lee FY, Fairchild CR, Stadnick LK, Rose WC, Solomon C, Wong H, Martel A, Wright JJ, Kramer R, Langley DR, Vyas DM. Discovery of a fluoroindolo[2,3-a]carbazole clinical candidate with broad spectrum antitumor activity in preclinical tumor models superior to the marketed oncology drug, CPT-11. J Med Chem. 2005 Apr 7; 48(7):2258-61.
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Chen Q, Tan E, Strauss JR, Zhang Z, Fenyk-Melody JE, Booth-Genthe C, Rushmore TH, Stearns RA, Evans DC, Baillie TA, Tang W. Effect of quinidine on the 10-hydroxylation of R-warfarin: species differences and clearance projection. J Pharmacol Exp Ther. 2004 Oct; 311(1):307-14.
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Miller KK, Cai J, Ripp SL, Pierce WM, Rushmore TH, Prough RA. Stereo- and regioselectivity account for the diversity of dehydroepiandrosterone (DHEA) metabolites produced by liver microsomal cytochromes P450. Drug Metab Dispos. 2004 Mar; 32(3):305-13.
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Mei Q, Tang C, Lin Y, Rushmore TH, Shou M. Inhibition kinetics of monoclonal antibodies against cytochromes P450. Drug Metab Dispos. 2002 Jun; 30(6):701-8.
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Curtis MT, Gilfor D, Farber JL. Lipid peroxidation increases the molecular order of microsomal membranes. Arch Biochem Biophys. 1984 Dec; 235(2):644-9.