Midazolam

"Midazolam" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.

Descriptor ID	D008874
MeSH Number(s)	D03.633.100.079.080.575
Concept/Terms	Midazolam Midazolam Midazolam Maleate Midazolam Maleate Maleate, Midazolam Dormicum Dormicum Versed Versed Midazolam Hydrochloride Midazolam Hydrochloride Hydrochloride, Midazolam Ro 21-3981 Ro 21-3981 Ro 21 3981 Ro 213981

Below are MeSH descriptors whose meaning is more general than "Midazolam".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Benzazepines [D03.633.100.079]
Benzodiazepines [D03.633.100.079.080]
Midazolam [D03.633.100.079.080.575]

Below are MeSH descriptors whose meaning is related to "Midazolam".

Below are MeSH descriptors whose meaning is more specific than "Midazolam".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Midazolam" by people in this website by year, and whether "Midazolam" was a major or minor topic of these publications.

Bar chart showing 20 publications over 12 distinct years, with a maximum of 3 publications in 2013 and 2015 and 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2000	1	0	1
2001	0	1	1
2003	1	1	2
2007	1	0	1
2010	1	1	2
2012	0	1	1
2013	2	1	3
2014	0	1	1
2015	2	1	3
2018	1	0	1
2019	1	2	3
2022	0	1	1

Below are the most recent publications written about "Midazolam" by people in Profiles.

Asadi-Pooya AA, Hosseini SA. Seizure rescue medications are missing from in-flight medical emergency kits. Epilepsy Behav. 2022 12; 137(Pt A):108976.

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Warrender W, Jones C, Selverian S, Lutsky K, Banner L, Beredjiklian PK. Perioperative Risks Are Similar for Normal versus Selected High-Body Mass Index Patients Undergoing Outpatient Hand and Elbow Surgery. Plast Reconstr Surg. 2019 11; 144(5):836e-840e.

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Yang J, Nikanjam M, Capparelli EV, Tsunoda SM, Greenberg HE, Penzak SR, Stoch SA, Bertino JS, Nafziger AN, Ma JD. Midazolam Limited Sampling Strategy With a Population Pharmacokinetic Approach to Simultaneously Estimate Cytochrome P450 (CYP) 3A Constitutive, Inhibition, and Induction/Activation Conditions in Healthy Adults. J Clin Pharmacol. 2019 11; 59(11):1495-1504.

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Ozawa Y, Ades A, Foglia EE, DeMeo S, Barry J, Sawyer T, Singh N, Glass K, Jung P, Quek BH, Johnston L, Kim J, Napolitano N, Shults J, Nadkarni VM, Nishisaki A. Premedication with neuromuscular blockade and sedation during neonatal intubation is associated with fewer adverse events. J Perinatol. 2019 06; 39(6):848-856.

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Yang J, Patel M, Nikanjam M, Capparelli EV, Tsunoda SM, Greenberg HE, Penzak SR, Aubrey Stoch S, Bertino JS, Nafziger AN, Ma JD. Midazolam Single Time Point Concentrations to Estimate Exposure and Cytochrome P450 (CYP) 3A Constitutive Activity Utilizing Limited Sampling Strategy With a Population Pharmacokinetic Approach. J Clin Pharmacol. 2018 09; 58(9):1205-1213.

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Goudra B, Nuzat A, Singh PM, Gouda GB, Carlin A, Manjunath AK. Cardiac arrests in patients undergoing gastrointestinal endoscopy: A retrospective analysis of 73,029 procedures. Saudi J Gastroenterol. 2015 Nov-Dec; 21(6):400-11.

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Tarquinio KM, Howell JD, Montgomery V, Turner DA, Hsing DD, Parker MM, Brown CA, Walls RM, Nadkarni VM, Nishisaki A. Current medication practice and tracheal intubation safety outcomes from a prospective multicenter observational cohort study. Pediatr Crit Care Med. 2015 Mar; 16(3):210-8.

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Masters JC, Harano DM, Greenberg HE, Tsunoda SM, Jang IJ, Ma JD. Limited sampling strategy of partial area under the concentration-time curves to estimate midazolam systemic clearance for cytochrome P450 3A phenotyping. Ther Drug Monit. 2015 Feb; 37(1):84-9.

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Kennedy DJ, Schneider B, Smuck M, Plastaras CT. The use of moderate sedation for the secondary prevention of adverse vasovagal reactions. Pain Med. 2015 Apr; 16(4):673-9.

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Fernandez A, Lantigua H, Lesch C, Shao B, Foreman B, Schmidt JM, Hirsch LJ, Mayer SA, Claassen J. High-dose midazolam infusion for refractory status epilepticus. Neurology. 2014 Jan 28; 82(4):359-65.

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