Midazolam

"Midazolam" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A short-acting hypnotic-sedative drug with anxiolytic and amnestic properties. It is used in dentistry, cardiac surgery, endoscopic procedures, as preanesthetic medication, and as an adjunct to local anesthesia. The short duration and cardiorespiratory stability makes it useful in poor-risk, elderly, and cardiac patients. It is water-soluble at pH less than 4 and lipid-soluble at physiological pH.

Descriptor ID	D008874
MeSH Number(s)	D03.633.100.079.080.575
Concept/Terms	Midazolam Midazolam Midazolam Maleate Midazolam Maleate Maleate, Midazolam Dormicum Dormicum Versed Versed Midazolam Hydrochloride Midazolam Hydrochloride Hydrochloride, Midazolam Ro 21-3981 Ro 21-3981 Ro 21 3981 Ro 213981

Below are MeSH descriptors whose meaning is more general than "Midazolam".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
Benzazepines [D03.633.100.079]
Benzodiazepines [D03.633.100.079.080]
Midazolam [D03.633.100.079.080.575]

Below are MeSH descriptors whose meaning is related to "Midazolam".

Below are MeSH descriptors whose meaning is more specific than "Midazolam".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Midazolam" by people in this website by year, and whether "Midazolam" was a major or minor topic of these publications.

Bar chart showing 33 publications over 18 distinct years, with a maximum of 4 publications in 2000 and 2013 and 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1997	1	0	1
1999	1	0	1
2000	4	0	4
2001	0	1	1
2003	1	1	2
2006	1	0	1
2007	1	0	1
2010	2	1	3
2012	0	1	1
2013	2	2	4
2014	0	1	1
2015	2	1	3
2018	1	0	1
2019	2	2	4
2021	1	0	1
2022	0	1	1
2024	2	0	2

Below are the most recent publications written about "Midazolam" by people in Profiles.

Fletman EW, Cleymaet S, Salvatore A, Devlin K, Pickard A, Shah SO. Ketamine plus midazolam compared to midazolam infusion for the management of refractory status epilepticus. Clin Neurol Neurosurg. 2024 11; 246:108592.

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Hagan L, David EM, Horton AR, Marx JO. Effects of Midazolam/Dexmedetomidine with Buprenorphine or Extended-release Buprenorphine Anesthesia in C57BL/6 Mice. J Am Assoc Lab Anim Sci. 2024 03 01; 63(2):172-181.

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Asadi-Pooya AA, Hosseini SA. Seizure rescue medications are missing from in-flight medical emergency kits. Epilepsy Behav. 2022 12; 137(Pt A):108976.

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Baldassari MP, Mouchtouris N, Velagapudi L, Nauheim D, Sweid A, Saiegh FA, Khanna O, Ghosh R, Herman M, Wyler D, Gooch MR, Tjoumakaris S, Jabbour P, Rosenwasser R, Romo V. Comparison of Anesthetic Agents Dexmedetomidine and Midazolam During Mechanical Thrombectomy. J Stroke Cerebrovasc Dis. 2021 Dec; 30(12):106117.

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Warrender W, Jones C, Selverian S, Lutsky K, Banner L, Beredjiklian PK. Perioperative Risks Are Similar for Normal versus Selected High-Body Mass Index Patients Undergoing Outpatient Hand and Elbow Surgery. Plast Reconstr Surg. 2019 11; 144(5):836e-840e.

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Rochani A, Lam E, Tanjuakio J, Hirose H, Kraft WK, Kaushal G. Simultaneous quantitative LC-MS method of ketamine, midazolam and their metabolites (dehydronorketamine, norketamine and 1hydroxymidazolam) for its application in patients on extracorporeal membrane oxygenation (ECMO) therapy. J Pharm Biomed Anal. 2020 Jan 30; 178:112947.

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Yang J, Nikanjam M, Capparelli EV, Tsunoda SM, Greenberg HE, Penzak SR, Stoch SA, Bertino JS, Nafziger AN, Ma JD. Midazolam Limited Sampling Strategy With a Population Pharmacokinetic Approach to Simultaneously Estimate Cytochrome P450 (CYP) 3A Constitutive, Inhibition, and Induction/Activation Conditions in Healthy Adults. J Clin Pharmacol. 2019 11; 59(11):1495-1504.

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Ozawa Y, Ades A, Foglia EE, DeMeo S, Barry J, Sawyer T, Singh N, Glass K, Jung P, Quek BH, Johnston L, Kim J, Napolitano N, Shults J, Nadkarni VM, Nishisaki A. Premedication with neuromuscular blockade and sedation during neonatal intubation is associated with fewer adverse events. J Perinatol. 2019 06; 39(6):848-856.

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Yang J, Patel M, Nikanjam M, Capparelli EV, Tsunoda SM, Greenberg HE, Penzak SR, Aubrey Stoch S, Bertino JS, Nafziger AN, Ma JD. Midazolam Single Time Point Concentrations to Estimate Exposure and Cytochrome P450 (CYP) 3A Constitutive Activity Utilizing Limited Sampling Strategy With a Population Pharmacokinetic Approach. J Clin Pharmacol. 2018 09; 58(9):1205-1213.

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Goudra B, Nuzat A, Singh PM, Gouda GB, Carlin A, Manjunath AK. Cardiac arrests in patients undergoing gastrointestinal endoscopy: A retrospective analysis of 73,029 procedures. Saudi J Gastroenterol. 2015 Nov-Dec; 21(6):400-11.

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