"Mitoguazone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Antineoplastic agent effective against myelogenous leukemia in experimental animals. Also acts as an inhibitor of animal S-adenosylmethionine decarboxylase.
| Descriptor ID |
D008935
|
| MeSH Number(s) |
D02.078.370.600
|
| Concept/Terms |
Mitoguazone- Mitoguazone
- MGBG
- Methylglyoxal Bis(guanylhydrazone)
|
Below are MeSH descriptors whose meaning is more general than "Mitoguazone".
Below are MeSH descriptors whose meaning is more specific than "Mitoguazone".
This graph shows the total number of publications written about "Mitoguazone" by people in this website by year, and whether "Mitoguazone" was a major or minor topic of these publications.
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Below are the most recent publications written about "Mitoguazone" by people in Profiles.
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Kuo BS, Korner G, Dryjski M, Bjornsson TD. Role of polyamines in the stimulation of synthesis and secretion of plasminogen activator from bovine aortic endothelial cells. J Cell Physiol. 1988 Oct; 137(1):192-8.
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Killen JY, Mitchell EP, Hoth DF, Willis LL, Gullo JJ, Smith FP, Schein PS, Woolley PV. Phase II studies of methyl glyoxal bis-guanylhydrazone (NSC 32946) in carcinoma of the colon and lung. Cancer. 1982 Oct 01; 50(7):1258-61.
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Spaulding MB, Barron SS, Comis RL, Richards F, Kennedy BJ, Pajak TF. Severe neurotoxicity with methyl G: CALGB experience. Med Pediatr Oncol. 1982; 10(5):521-4.
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Fuks JZ, Van Echo DA, Aisner J, Mitchell EP, Woolley PV, Wiernik PH. Phase II trial of methyl-G (methylglyoxal bis-guanylhydrazone) in patients with metastatic renal cell carcinoma. Cancer Clin Trials. 1981; 4(4):411-4.
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Bachrach U, Brem S, Wertman SB, Schnur LF, Greenblatt CL. Leishmania spp.: effect of inhibitors on growth and on polyamine and macromolecular syntheses. Exp Parasitol. 1979 Dec; 48(3):464-70.