Myelin Sheath

"Myelin Sheath" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The lipid-rich sheath surrounding AXONS in both the CENTRAL NERVOUS SYSTEMS and PERIPHERAL NERVOUS SYSTEM. The myelin sheath is an electrical insulator and allows faster and more energetically efficient conduction of impulses. The sheath is formed by the cell membranes of glial cells (SCHWANN CELLS in the peripheral and OLIGODENDROGLIA in the central nervous system). Deterioration of the sheath in DEMYELINATING DISEASES is a serious clinical problem.

Descriptor ID	D009186
MeSH Number(s)	A08.637.600.500 A08.637.800.500 A08.675.542.512.560 A08.800.800.690.500 A10.755.503 A11.284.149.165.600 A11.650.600.500 A11.650.800.500 A11.671.501.512.560 A11.671.514.553
Concept/Terms	Myelin Sheath Myelin Sheath Myelin Sheaths Sheath, Myelin Sheaths, Myelin Myelin Myelin

Below are MeSH descriptors whose meaning is more general than "Myelin Sheath".

Anatomy [A]
Nervous System [A08]
Neuroglia [A08.637]
Oligodendroglia [A08.637.600]
Myelin Sheath [A08.637.600.500]
Schwann Cells [A08.637.800]
Myelin Sheath [A08.637.800.500]
Neurons [A08.675]
Nerve Fibers [A08.675.542]
Nerve Fibers, Myelinated [A08.675.542.512]
Myelin Sheath [A08.675.542.512.560]
Peripheral Nervous System [A08.800]
Peripheral Nerves [A08.800.800]
Schwann Cells [A08.800.800.690]
Myelin Sheath [A08.800.800.690.500]
Tissues [A10]
Nerve Tissue [A10.755]
Myelin Sheath [A10.755.503]
Cells [A11]
Cellular Structures [A11.284]
Cell Membrane [A11.284.149]
Cell Membrane Structures [A11.284.149.165]
Myelin Sheath [A11.284.149.165.600]
Neuroglia [A11.650]
Oligodendroglia [A11.650.600]
Myelin Sheath [A11.650.600.500]
Schwann Cells [A11.650.800]
Myelin Sheath [A11.650.800.500]
Neurons [A11.671]
Nerve Fibers [A11.671.501]
Nerve Fibers, Myelinated [A11.671.501.512]
Myelin Sheath [A11.671.501.512.560]
Nerve Fibers, Myelinated [A11.671.514]
Myelin Sheath [A11.671.514.553]

Below are MeSH descriptors whose meaning is related to "Myelin Sheath".

Below are MeSH descriptors whose meaning is more specific than "Myelin Sheath".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Myelin Sheath" by people in this website by year, and whether "Myelin Sheath" was a major or minor topic of these publications.

Bar chart showing 20 publications over 12 distinct years, with a maximum of 4 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	0	2	2
2002	2	1	3
2003	1	1	2
2004	1	0	1
2005	1	1	2
2006	0	1	1
2007	1	0	1
2008	3	1	4
2009	0	1	1
2010	1	0	1
2014	0	1	1
2016	0	1	1

Below are the most recent publications written about "Myelin Sheath" by people in Profiles.

Zhang Y, Li X, Ciric B, Ma CG, Gran B, Rostami A, Zhang GX. Effect of Fingolimod on Neural Stem Cells: A Novel Mechanism and Broadened Application for Neural Repair. Mol Ther. 2017 Feb 01; 25(2):401-415.

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Zivadinov R, Dwyer MG, Markovic-Plese S, Kennedy C, Bergsland N, Ramasamy DP, Durfee J, Hojnacki D, Hayward B, Dangond F, Weinstock-Guttman B. Effect of treatment with interferon beta-1a on changes in voxel-wise magnetization transfer ratio in normal appearing brain tissue and lesions of patients with relapsing-remitting multiple sclerosis: a 24-week, controlled pilot study. PLoS One. 2014; 9(3):e91098.

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Desai MK, Mastrangelo MA, Ryan DA, Sudol KL, Narrow WC, Bowers WJ. Early oligodendrocyte/myelin pathology in Alzheimer's disease mice constitutes a novel therapeutic target. Am J Pathol. 2010 Sep; 177(3):1422-35.

View in: PubMed
Das Sarma J, Kenyon LC, Hingley ST, Shindler KS. Mechanisms of primary axonal damage in a viral model of multiple sclerosis. J Neurosci. 2009 Aug 19; 29(33):10272-80.

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Montes M, Zhang X, Berthelot L, Laplaud DA, Brouard S, Jin J, Rogan S, Armao D, Jewells V, Soulillou JP, Markovic-Plese S. Oligoclonal myelin-reactive T-cell infiltrates derived from multiple sclerosis lesions are enriched in Th17 cells. Clin Immunol. 2009 Feb; 130(2):133-44.

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Yang J, Rostami A, Zhang GX. Cellular remyelinating therapy in multiple sclerosis. J Neurol Sci. 2009 Jan 15; 276(1-2):1-5.

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Das Sarma J, Iacono K, Gard L, Marek R, Kenyon LC, Koval M, Weiss SR. Demyelinating and nondemyelinating strains of mouse hepatitis virus differ in their neural cell tropism. J Virol. 2008 Jun; 82(11):5519-26.

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Iocca HA, Plant SR, Wang Y, Runkel L, O'Connor BP, Lundsmith ET, Hahm K, van Deventer HW, Burkly LC, Ting JP. TNF superfamily member TWEAK exacerbates inflammation and demyelination in the cuprizone-induced model. J Neuroimmunol. 2008 Feb; 194(1-2):97-106.

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Warrington AE, Bieber AJ, Ciric B, Pease LR, Van Keulen V, Rodriguez M. A recombinant human IgM promotes myelin repair after a single, very low dose. J Neurosci Res. 2007 Apr; 85(5):967-76.

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Taylor RM, Lee JP, Palacino JJ, Bower KA, Li J, Vanier MT, Wenger DA, Sidman RL, Snyder EY. Intrinsic resistance of neural stem cells to toxic metabolites may make them well suited for cell non-autonomous disorders: evidence from a mouse model of Krabbe leukodystrophy. J Neurochem. 2006 Jun; 97(6):1585-99.

View in: PubMed

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