"Notochord" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cartilaginous rod of mesodermal cells at the dorsal midline of all CHORDATE embryos. In lower vertebrates, notochord is the backbone of support. In the higher vertebrates, notochord is a transient structure, and segments of the vertebral column will develop around it. Notochord is also a source of midline signals that pattern surrounding tissues including the NEURAL TUBE development.
| Descriptor ID |
D009672
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| MeSH Number(s) |
A16.660
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Notochord".
Below are MeSH descriptors whose meaning is more specific than "Notochord".
This graph shows the total number of publications written about "Notochord" by people in this website by year, and whether "Notochord" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 |
| 2010 | 2 | 0 | 2 |
| 2011 | 2 | 1 | 3 |
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Notochord" by people in Profiles.
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Plastaras C, Tsay T, Schran S, Zhang Y, Becker S, Pukenas B. Vertebral Benign Notochordal Cell Tumor (BNCT) as an Incidental Finding in Cervical Radiculitis. PM R. 2015 Nov; 7(11):1198-1200.
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Pulina MV, Hou SY, Mittal A, Julich D, Whittaker CA, Holley SA, Hynes RO, Astrof S. Essential roles of fibronectin in the development of the left-right embryonic body plan. Dev Biol. 2011 Jun 15; 354(2):208-20.
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Nishiguchi T, Mochizuki K, Ohsawa M, Inoue T, Kageyama K, Suzuki A, Takami T, Miki Y. Differentiating benign notochordal cell tumors from chordomas: radiographic features on MRI, CT, and tomography. AJR Am J Roentgenol. 2011 Mar; 196(3):644-50.
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Risbud MV, Shapiro IM. Notochordal cells in the adult intervertebral disc: new perspective on an old question. Crit Rev Eukaryot Gene Expr. 2011; 21(1):29-41.
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Risbud MV, Schaer TP, Shapiro IM. Toward an understanding of the role of notochordal cells in the adult intervertebral disc: from discord to accord. Dev Dyn. 2010 Aug; 239(8):2141-8.
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Shapiro IM, Risbud MV. Transcriptional profiling of the nucleus pulposus: say yes to notochord. Arthritis Res Ther. 2010; 12(3):117.
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Oguz E, Tsai TT, Di Martino A, Guttapalli A, Albert TJ, Shapiro IM, Risbud MV. Galectin-3 expression in the intervertebral disc: a useful marker of the notochord phenotype? Spine (Phila Pa 1976). 2007 Jan 1; 32(1):9-16.