"Optic Neuritis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Inflammation of the optic nerve. Commonly associated conditions include autoimmune disorders such as MULTIPLE SCLEROSIS, infections, and granulomatous diseases. Clinical features include retro-orbital pain that is aggravated by eye movement, loss of color vision, and contrast sensitivity that may progress to severe visual loss, an afferent pupillary defect (Marcus-Gunn pupil), and in some instances optic disc hyperemia and swelling. Inflammation may occur in the portion of the nerve within the globe (neuropapillitis or anterior optic neuritis) or the portion behind the globe (retrobulbar neuritis or posterior optic neuritis).
Descriptor ID |
D009902
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MeSH Number(s) |
C10.292.700.550 C11.640.576
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Concept/Terms |
Optic Neuritis- Optic Neuritis
- Neuritides, Optic
- Neuritis, Optic
- Optic Neuritides
Neuropapillitis- Neuropapillitis
- Neuropapillitides
- Anterior Optic Neuritis
- Anterior Optic Neuritides
- Neuritides, Anterior Optic
- Neuritis, Anterior Optic
- Optic Neuritides, Anterior
- Optic Neuritis, Anterior
Retrobulbar Neuritis- Retrobulbar Neuritis
- Neuritides, Retrobulbar
- Neuritis, Retrobulbar
- Retrobulbar Neuritides
- Posterior Optic Neuritis
- Neuritides, Posterior Optic
- Neuritis, Posterior Optic
- Optic Neuritides, Posterior
- Optic Neuritis, Posterior
- Posterior Optic Neuritides
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Below are MeSH descriptors whose meaning is more general than "Optic Neuritis".
Below are MeSH descriptors whose meaning is more specific than "Optic Neuritis".
This graph shows the total number of publications written about "Optic Neuritis" by people in this website by year, and whether "Optic Neuritis" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 |
2006 | 1 | 0 | 1 |
2007 | 1 | 0 | 1 |
2008 | 2 | 0 | 2 |
2009 | 2 | 0 | 2 |
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Below are the most recent publications written about "Optic Neuritis" by people in Profiles.
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Dutt M, Tabuena P, Ventura E, Rostami A, Shindler KS. Timing of corticosteroid therapy is critical to prevent retinal ganglion cell loss in experimental optic neuritis. Invest Ophthalmol Vis Sci. 2010 Mar; 51(3):1439-45.
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Techavipoo U, Okai AF, Lackey J, Shi J, Dresner MA, Leist TP, Lai S. Toward a practical protocol for human optic nerve DTI with EPI geometric distortion correction. J Magn Reson Imaging. 2009 Oct; 30(4):699-707.
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Shindler KS, Kenyon LC, Dutt M, Hingley ST, Das Sarma J. Experimental optic neuritis induced by a demyelinating strain of mouse hepatitis virus. J Virol. 2008 Sep; 82(17):8882-6.
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Shindler KS, Ventura E, Dutt M, Rostami A. Inflammatory demyelination induces axonal injury and retinal ganglion cell apoptosis in experimental optic neuritis. Exp Eye Res. 2008 Sep; 87(3):208-13.
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Shindler KS, Ventura E, Rex TS, Elliott P, Rostami A. SIRT1 activation confers neuroprotection in experimental optic neuritis. Invest Ophthalmol Vis Sci. 2007 Aug; 48(8):3602-9.
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Shindler KS, Guan Y, Ventura E, Bennett J, Rostami A. Retinal ganglion cell loss induced by acute optic neuritis in a relapsing model of multiple sclerosis. Mult Scler. 2006 Oct; 12(5):526-32.
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Faro SH, Mohamed FB, Tracy JI, Elfont RM, Pinus AB, Lublin FD, Koenigsberg RA, Chen CY, Tsai FY. Quantitative functional MR imaging of the visual cortex at 1.5 T as a function of luminance contrast in healthy volunteers and patients with multiple sclerosis. AJNR Am J Neuroradiol. 2002 Jan; 23(1):59-65.