"Pepsin A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Formed from pig pepsinogen by cleavage of one peptide bond. The enzyme is a single polypeptide chain and is inhibited by methyl 2-diaazoacetamidohexanoate. It cleaves peptides preferentially at the carbonyl linkages of phenylalanine or leucine and acts as the principal digestive enzyme of gastric juice.
| Descriptor ID |
D010434
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| MeSH Number(s) |
D08.811.277.656.074.500.700 D08.811.277.656.300.048.700
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pepsin A".
Below are MeSH descriptors whose meaning is more specific than "Pepsin A".
This graph shows the total number of publications written about "Pepsin A" by people in this website by year, and whether "Pepsin A" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pepsin A" by people in Profiles.
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Farhath S, He Z, Saslow J, Soundar S, Amendolia B, Bhat V, Pyon K, Stahl G, Mehta D, Aghai ZH. Detection of pepsin in mouth swab: correlation with clinical gastroesophageal reflux in preterm infants. J Matern Fetal Neonatal Med. 2013 May; 26(8):819-24.
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Seidler DG, Schaefer L, Robenek H, Iozzo RV, Kresse H, Schönherr E. A physiologic three-dimensional cell culture system to investigate the role of decorin in matrix organisation and cell survival. Biochem Biophys Res Commun. 2005 Jul 15; 332(4):1162-70.
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Steplewski A, Ito H, Rucker E, Brittingham RJ, Alabyeva T, Gandhi M, Ko FK, Birk DE, Jimenez SA, Fertala A. Position of single amino acid substitutions in the collagen triple helix determines their effect on structure of collagen fibrils. J Struct Biol. 2004 Dec; 148(3):326-37.
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Sieron AL, Louneva N, Fertala A. Site-specific interaction of bone morphogenetic protein 2 with procollagen II. Cytokine. 2002 May 21; 18(4):214-21.