Phosphodiesterase Inhibitors
"Phosphodiesterase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds which inhibit or antagonize the biosynthesis or actions of phosphodiesterases.
Descriptor ID |
D010726
|
MeSH Number(s) |
D27.505.519.389.735
|
Concept/Terms |
Phosphodiesterase Inhibitors- Phosphodiesterase Inhibitors
- Phosphodiesterase Antagonists
- Phosphoric Diester Hydrolase Inhibitors
- Antiphosphodiesterases
|
Below are MeSH descriptors whose meaning is more general than "Phosphodiesterase Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Phosphodiesterase Inhibitors".
This graph shows the total number of publications written about "Phosphodiesterase Inhibitors" by people in this website by year, and whether "Phosphodiesterase Inhibitors" was a major or minor topic of these publications.
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click here.
Year | Major Topic | Minor Topic | Total |
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1999 | 2 | 0 | 2 |
2001 | 0 | 2 | 2 |
2002 | 3 | 1 | 4 |
2003 | 2 | 2 | 4 |
2004 | 1 | 1 | 2 |
2005 | 1 | 2 | 3 |
2006 | 1 | 0 | 1 |
2007 | 0 | 1 | 1 |
2012 | 1 | 1 | 2 |
2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Phosphodiesterase Inhibitors" by people in Profiles.
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Gopalakrishna G, Ithman MH, Lauriello J. Update on New and Emerging Treatments for Schizophrenia. Psychiatr Clin North Am. 2016 06; 39(2):217-38.
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Tazzeo T, Bates G, Roman HN, Lauzon AM, Khasnis MD, Eto M, Janssen LJ. Caffeine relaxes smooth muscle through actin depolymerization. Am J Physiol Lung Cell Mol Physiol. 2012 Aug 15; 303(4):L334-42.
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Almario B, Wu S, Peng J, Alapati D, Chen S, Sosenko IR. Pentoxifylline and prevention of hyperoxia-induced lung -injury in neonatal rats. Pediatr Res. 2012 May; 71(5):583-9.
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Windhofer F, Wu W, Iliakis G. Low levels of DNA ligases III and IV sufficient for effective NHEJ. J Cell Physiol. 2007 Nov; 213(2):475-83.
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Kowey PR, Yan GX. "Doctor, why didn't you tell me about this before the ICD?". J Cardiovasc Electrophysiol. 2006 Mar; 17(3):296-7.
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Hollander JE. Emergency department considerations regarding erectile dysfunction. Am J Cardiol. 2005 Dec 26; 96(12B):73M-75M.
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Cook DG, Li X, Cherry SD, Cantrell AR. Presenilin 1 deficiency alters the activity of voltage-gated Ca2+ channels in cultured cortical neurons. J Neurophysiol. 2005 Dec; 94(6):4421-9.
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Kowey PR, Yan GX. Making a silk purse out of a sow's ear. J Am Coll Cardiol. 2005 Aug 16; 46(4):688-9.
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Jung AS, Quaile MP, Mills GD, Bednarik DP, Houser SR, Margulies KB. Pharmacological effects of ATI22-107 [2-(2-{2-[2-chloro-4-(6-oxo-1,4,5,6-tetrahydro-pyridazin-3-yl)-phenoxy]-acetylamino}-ethoxymethyl)-4-(2-chloro-phenyl)-6-methyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid dimethyl ester)], a novel dual pharmacophore, on myocyte calcium cycling and contractility. J Pharmacol Exp Ther. 2005 Feb; 312(2):517-24.
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Losco PE, Evans EW, Barat SA, Blackshear PE, Reyderman L, Fine JS, Bober LA, Anthes JC, Mirro EJ, Cuss FM. The toxicity of SCH 351591, a novel phosphodiesterase-4 inhibitor, in Cynomolgus monkeys. Toxicol Pathol. 2004 May-Jun; 32(3):295-308.