"Phosphonoacetic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A simple organophosphorus compound that inhibits DNA polymerase, especially in viruses and is used as an antiviral agent.
| Descriptor ID |
D010746
|
| MeSH Number(s) |
D02.241.081.018.677 D02.705.429.875
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Phosphonoacetic Acid".
Below are MeSH descriptors whose meaning is more specific than "Phosphonoacetic Acid".
This graph shows the total number of publications written about "Phosphonoacetic Acid" by people in this website by year, and whether "Phosphonoacetic Acid" was a major or minor topic of these publications.
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Below are the most recent publications written about "Phosphonoacetic Acid" by people in Profiles.
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Meropol NJ, Creaven PJ, Petrelli NJ. Metastatic colorectal cancer: advances in biochemical modulation and new drug development. Semin Oncol. 1995 Oct; 22(5):509-24.
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Ardalan B, Stridhar K, Reddy R, Benedetto P, Richman S, Waldman S, Morrell L, Feun L, Savaraj N, Livingstone A. Phase I study of high dose 5-fluorouracil and high dose Leucovorin with low dose phosphonacetyl-L-aspartic acid in patients with advanced malignancies. Int J Radiat Oncol Biol Phys. 1992; 22(3):511-4.
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Rosvold E, Schilder R, Walczak J, DiFino SM, Flynn PJ, Banerjee TK, Heim WJ, Engstrom PF, Ozols RF, O'Dwyer PJ. Phase II trial of PALA in combination with 5-fluorouracil in advanced pancreatic cancer. Cancer Chemother Pharmacol. 1992; 29(4):305-8.
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Ardalan B, Sridhar KS, Benedetto P, Richman S, Waldman S, Morrell L, Feun L, Savaraj N, Fodor M, Livingstone A. A phase I, II study of high-dose 5-fluorouracil and high-dose leucovorin with low-dose phosphonacetyl-L-aspartic acid in patients with advanced malignancies. Cancer. 1991 Sep 15; 68(6):1242-6.
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Strayer DS, Skaletsky E, Leibowitz JL. Inhibition of virus replication does not alter malignant rabbit fibroma virus-induced immunosuppression. Clin Exp Immunol. 1986 Oct; 66(1):25-36.