Arie Horowitz

TitleAssoc Professor
InstitutionThomas Jefferson University
DepartmentHematology
Address1020 Locust St.
Philadelphia PA 19107
Phone215-955-3824
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Horowitz A, Saugier-Veber P, Gilard V. Inference of Diagnostic Markers and Therapeutic Targets From CSF Proteomics for the Treatment of Hydrocephalus. Front Cell Neurosci. 2020; 14:576028. PMID: 33192320.
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    2. Simonneau C, Yang J, Kong X, Kilker R, Edelstein L, Fortina P, Londin E, Horowitz A. Validation of a Miniaturized Permeability Assay Compatible with CRISPR-Mediated Genome-Wide Screen. Sci Rep. 2019 Oct 02; 9(1):14238. PMID: 31578372.
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    3. Yang J, Simonneau C, Kilker R, Oakley L, Byrne MD, Nichtova Z, Stefanescu I, Pardeep-Kumar F, Tripathi S, Londin E, Saugier-Veber P, Willard B, Thakur M, Pickup S, Ishikawa H, Schroten H, Smeyne R, Horowitz A. Murine MPDZ-linked hydrocephalus is caused by hyperpermeability of the choroid plexus. EMBO Mol Med. 2019 Jan; 11(1). PMID: 30518636.
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    4. Yang J, Wu C, Stefanescu I, Horowitz A. Analysis of Retinoic Acid-induced Neural Differentiation of Mouse Embryonic Stem Cells in Two and Three-dimensional Embryoid Bodies. J Vis Exp. 2017 Apr 22; (122). PMID: 28518115.
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    5. Horowitz A. Letter by Horowitz Regarding Article, "Protein Interactions at Endothelial Junctions and Signaling Mechanisms Regulating Endothelial Permeability". Circ Res. 2017 Mar 03; 120(5):e27. PMID: 28254807.
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    6. Horowitz A, Yang J, Cai J, Iacovitti L. The versatility of RhoA activities in neural differentiation. Small GTPases. 2017 Jan 26; 1-7. PMID: 28125332.
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    7. Yang J, Wu C, Stefanescu I, Jakobsson L, Chervoneva I, Horowitz A. RhoA inhibits neural differentiation in murine stem cells through multiple mechanisms. Sci Signal. 2016; 9(438):ra76. PMID: 27460990.
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    8. Ngok SP, Geyer R, Liu M, Kourtidis A, Agrawal S, Wu C, Seerapu HR, Lewis-Tuffin LJ, Moodie KL, Huveldt D, Marx R, Baraban JM, Storz P, Horowitz A, Anastasiadis PZ. VEGF and Angiopoietin-1 exert opposing effects on cell junctions by regulating the Rho GEF Syx. J Cell Biol. 2012 Dec 24; 199(7):1103-15. PMID: 23253477.
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    9. Fan Y, Arif A, Gong Y, Jia J, Eswarappa SM, Willard B, Horowitz A, Graham LM, Penn MS, Fox PL. Stimulus-dependent phosphorylation of profilin-1 in angiogenesis. Nat Cell Biol. 2012 Oct; 14(10):1046-56. PMID: 23000962; PMCID: PMC3619429.
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    10. Wu C, Horowitz A. Membrane traffic as a coordinator of cell migration and junction remodeling. Commun Integr Biol. 2011 Nov 1; 4(6):703-5. PMID: 22446532.
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    11. Wu C, Agrawal S, Vasanji A, Drazba J, Sarkaria S, Xie J, Welch CM, Liu M, Anand-Apte B, Horowitz A. Rab13-dependent trafficking of RhoA is required for directional migration and angiogenesis. J Biol Chem. 2011 Jul 01; 286(26):23511-20. PMID: 21543326.
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    12. Horowitz A, Simons M. Branching morphogenesis. Circ Res. 2009 Jan 30; 104(2):e21. PMID: 19179661; PMCID: PMC2844453.
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    13. Horowitz A, Simons M. Branching morphogenesis. Circ Res. 2008 Oct 10; 103(8):784-95. PMID: 18845818.
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    14. Ernkvist M, Luna Persson N, Audebert S, Lecine P, Sinha I, Liu M, Schlueter M, Horowitz A, Aase K, Weide T, Borg JP, Majumdar A, Holmgren L. The Amot/Patj/Syx signaling complex spatially controls RhoA GTPase activity in migrating endothelial cells. Blood. 2009 Jan 01; 113(1):244-53. PMID: 18824598; PMCID: PMC2614636.
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    15. Garnaas MK, Moodie KL, Liu ML, Samant GV, Li K, Marx R, Baraban JM, Horowitz A, Ramchandran R. Syx, a RhoA guanine exchange factor, is essential for angiogenesis in Vivo. Circ Res. 2008 Sep 26; 103(7):710-6. PMID: 18757825; PMCID: PMC2758496.
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    16. Salikhova A, Wang L, Lanahan AA, Liu M, Simons M, Leenders WP, Mukhopadhyay D, Horowitz A. Vascular endothelial growth factor and semaphorin induce neuropilin-1 endocytosis via separate pathways. Circ Res. 2008 Sep 12; 103(6):e71-9. PMID: 18723443; PMCID: PMC2674948.
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    17. Liu M, Horowitz A. A PDZ-binding motif as a critical determinant of Rho guanine exchange factor function and cell phenotype. Mol Biol Cell. 2006 Apr; 17(4):1880-7. PMID: 16467373; PMCID: PMC1415294.
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