Thomas Jefferson University

Anna Pluciennik

TitleAsst Professor
InstitutionThomas Jefferson University
DepartmentBiochem & Molecular Biology
Address1020 Locust St.
Philadelphia PA 19107
Phone215-503-2035
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Phadte AS, Bhatia M, Ebert H, Abdullah H, Elrazaq EA, Komolov KE, Pluciennik A. FAN1 removes triplet repeat extrusions via a PCNA- and RFC-dependent mechanism. Proc Natl Acad Sci U S A. 2023 08 15; 120(33):e2302103120. PMID: 37549289.
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    2. Sengupta M, Pluciennik A, Merry DE. The role of ubiquitination in spinal and bulbar muscular atrophy. Front Mol Neurosci. 2022; 15:1020143. PMID: 36277484.
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    3. Pluciennik A, Liu Y, Molotsky E, Marsh GB, Ranxhi B, Arnold FJ, St-Cyr S, Davidson B, Pourshafie N, Lieberman AP, Gu W, Todi SV, Merry DE. Deubiquitinase USP7 contributes to the pathogenicity of spinal and bulbar muscular atrophy. J Clin Invest. 2021 Jan 04; 131(1). PMID: 33170804.
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    4. Iyer RR, Pluciennik A. DNA Mismatch Repair and its Role in Huntington's Disease. J Huntingtons Dis. 2021; 10(1):75-94. PMID: 33579865.
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    5. Arnold FJ, Pluciennik A, Merry DE. Impaired Nuclear Export of Polyglutamine-Expanded Androgen Receptor in Spinal and Bulbar Muscular Atrophy. Sci Rep. 2019 Jan 15; 9(1):119. PMID: 30644418.
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    6. Zboray L, Pluciennik A, Curtis D, Liu Y, Berman-Booty LD, Orr C, Kesler CT, Berger T, Gioeli D, Paschal BM, Merry DE. Preventing the Androgen Receptor N/C Interaction Delays Disease Onset in a Mouse Model of SBMA. Cell Rep. 2015 Dec 15; 13(10):2312-23. PMID: 26673324.
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    7. Heine EM, Berger TR, Pluciennik A, Orr CR, Zboray L, Merry DE. Proteasome-mediated Proteolysis of the Polyglutamine-expanded Androgen Receptor Is a Late Event in Spinal and Bulbar Muscular Atrophy (SBMA) Pathogenesis. J Biol Chem. 2015 May 15; 290(20):12572-84. PMID: 25795778.
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    8. Iyer RR, Pluciennik A, Napierala M, Wells RD. DNA triplet repeat expansion and mismatch repair. Annu Rev Biochem. 2015; 84:199-226. PMID: 25580529.
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    9. Pluciennik A, Burdett V, Baitinger C, Iyer RR, Shi K, Modrich P. Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLa endonuclease activation. Proc Natl Acad Sci U S A. 2013 Jul 23; 110(30):12277-82. PMID: 23840062.
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    10. Pluciennik A, Dzantiev L, Iyer RR, Constantin N, Kadyrov FA, Modrich P. PCNA function in the activation and strand direction of MutLa endonuclease in mismatch repair. Proc Natl Acad Sci U S A. 2010 Sep 14; 107(37):16066-71. PMID: 20713735.
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    11. Iyer RR, Pluciennik A, Genschel J, Tsai MS, Beese LS, Modrich P. MutLalpha and proliferating cell nuclear antigen share binding sites on MutSbeta. J Biol Chem. 2010 Apr 9; 285(15):11730-9. PMID: 20154325.
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    12. Pluciennik A, Burdett V, Lukianova O, O'Donnell M, Modrich P. Involvement of the beta clamp in methyl-directed mismatch repair in vitro. J Biol Chem. 2009 Nov 20; 284(47):32782-91. PMID: 19783657.
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    13. Pluciennik A, Modrich P. Protein roadblocks and helix discontinuities are barriers to the initiation of mismatch repair. Proc Natl Acad Sci U S A. 2007 Jul 31; 104(31):12709-13. PMID: 17620611.
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    14. Iyer RR, Pluciennik A, Burdett V, Modrich PL. DNA mismatch repair: functions and mechanisms. Chem Rev. 2006 Feb; 106(2):302-23. PMID: 16464007.
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    15. Bowers LM, Lapoint K, Anthony L, Pluciennik A, Filutowicz M. Bacterial expression system with tightly regulated gene expression and plasmid copy number. Gene. 2004 Sep 29; 340(1):11-8. PMID: 15556290.
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    16. Pluciennik A, Iyer RR, Napierala M, Larson JE, Filutowicz M, Wells RD. Long CTG.CAG repeats from myotonic dystrophy are preferred sites for intermolecular recombination. J Biol Chem. 2002 Sep 13; 277(37):34074-86. PMID: 12087090.
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    17. Napierala M, Parniewski P, Pluciennik A, Wells RD. Long CTG.CAG repeat sequences markedly stimulate intramolecular recombination. J Biol Chem. 2002 Sep 13; 277(37):34087-100. PMID: 12045198.
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