Thomas Jefferson University

Elda Grabocka

TitleAssoc Professor
InstitutionThomas Jefferson University
DepartmentCancer Biology
Address233 S. 10th Street
Philadelphia PA 19107
Phone215-503-7783
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Redding A, Grabocka E. Stress granules and hormetic adaptation of cancer. Trends Cancer. 2023 Sep 11. PMID: 37704502.
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    2. Redding A, Grabocka E. A Splendid New Beginning at the End of a 40-Year Quest: The First KRASG12D Inhibitor in Pancreatic Cancer. Cancer Discov. 2023 Feb 06; 13(2):260-262. PMID: 36744321.
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    3. Fonteneau G, Redding A, Hoag-Lee H, Sim ES, Heinrich S, Gaida MM, Grabocka E. Stress Granules determine the Development of Obesity-associated Pancreatic Cancer. Cancer Discov. 2022 Jun 08. PMID: 35674408.
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    4. Redding A, Aplin AE, Grabocka E. RAS-mediated tumor stress adaptation and the targeting opportunities it presents. Dis Model Mech. 2022 02 01; 15(2). PMID: 35147163.
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    5. Song MS, Grabocka E. Stress Granules in Cancer. Rev Physiol Biochem Pharmacol. 2020 Aug 14. PMID: 32789791.
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    6. Sim E, Irollo E, Grabocka E. Evaluating Stress Granules in Pancreatic Cancer In Vitro and In Vivo. Methods Mol Biol. 2019; 1882:183-195. PMID: 30378055.
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    7. Grabocka E, Bar-Sagi D. Mutant KRAS Enhances Tumor Cell Fitness by Upregulating Stress Granules. Cell. 2016 Dec 15; 167(7):1803-1813.e12. PMID: 27984728.
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    8. Sundstrom A, Grabocka E, Bar-Sagi D, Mishra B. Histological Image Processing Features Induce a Quantitative Characterization of Chronic Tumor Hypoxia. PLoS One. 2016; 11(4):e0153623. PMID: 27093539.
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    9. Helms MC, Grabocka E, Martz MK, Fischer CC, Suzuki N, Wedegaertner PB. Mitotic-dependent phosphorylation of leukemia-associated RhoGEF (LARG) by Cdk1. Cell Signal. 2016 Jan; 28(1):43-52. PMID: 26483157.
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    10. Kamphorst JJ, Nofal M, Commisso C, Hackett SR, Lu W, Grabocka E, Vander Heiden MG, Miller G, Drebin JA, Bar-Sagi D, Thompson CB, Rabinowitz JD. Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein. Cancer Res. 2015 Feb 1; 75(3):544-53. PMID: 25644265.
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    11. Grabocka E, Commisso C, Bar-Sagi D. Molecular pathways: targeting the dependence of mutant RAS cancers on the DNA damage response. Clin Cancer Res. 2015 Mar 15; 21(6):1243-7. PMID: 25424849.
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    12. Grabocka E, Pylayeva-Gupta Y, Jones MJ, Lubkov V, Yemanaberhan E, Taylor L, Jeng HH, Bar-Sagi D. Wild-type H- and N-Ras promote mutant K-Ras-driven tumorigenesis by modulating the DNA damage response. Cancer Cell. 2014 Feb 10; 25(2):243-56. PMID: 24525237.
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    13. Martz MK, Grabocka E, Beeharry N, Yen TJ, Wedegaertner PB. Leukemia-associated RhoGEF (LARG) is a novel RhoGEF in cytokinesis and required for the proper completion of abscission. Mol Biol Cell. 2013 Sep; 24(18):2785-94. PMID: 23885121.
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    14. Commisso C, Davidson SM, Soydaner-Azeloglu RG, Parker SJ, Kamphorst JJ, Hackett S, Grabocka E, Nofal M, Drebin JA, Thompson CB, Rabinowitz JD, Metallo CM, Vander Heiden MG, Bar-Sagi D. Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells. Nature. 2013 May 30; 497(7451):633-7. PMID: 23665962.
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    15. Pylayeva-Gupta Y, Grabocka E, Bar-Sagi D. RAS oncogenes: weaving a tumorigenic web. Nat Rev Cancer. 2011 Oct 13; 11(11):761-74. PMID: 21993244.
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    16. Grabocka E, Bar-Sagi D. Raf-1 and squamous cell carcinoma: Rok-ing the boat. Cancer Cell. 2009 Aug 4; 16(2):85-6. PMID: 19647217.
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    17. Grabocka E, Wedegaertner PB. Disruption of oligomerization induces nucleocytoplasmic shuttling of leukemia-associated rho Guanine-nucleotide exchange factor. Mol Pharmacol. 2007 Oct; 72(4):993-1002. PMID: 17609419.
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    18. Grabocka E, Wedegaertner PB. Functional consequences of G alpha 13 mutations that disrupt interaction with p115RhoGEF. Oncogene. 2005 Mar 24; 24(13):2155-65. PMID: 15735747.
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