Scott Gygax

TitleAsst Prof CHP
InstitutionThomas Jefferson University
DepartmentBioscience Technology
Address130 S. 9th Street
Philadelphia PA 19107
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Moore KR, Tomar M, Taylor BD, Gygax SE, Hilbert DW, Baird DD. Mycoplasma genitalium and Bacterial Vaginosis-Associated Bacteria in a Non-Clinic-Based Sample of African American Women. Sex Transm Dis. 2021 Feb 01; 48(2):118-122. PMID: 32925595.
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    2. Stemmer SM, Mordechai E, Adelson ME, Gygax SE, Hilbert DW. Trichomonas vaginalis is most frequently detected in women at the age of peri-/premenopause: an unusual pattern for a sexually transmitted pathogen. Am J Obstet Gynecol. 2018 Mar; 218(3):328.e1-328.e13. PMID: 29247635.
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    3. Ventolini G, Khandelwal N, Hutton K, Lugo J, Gygax SE, Schlabritz-Loutsevitch N. Obesity and recurrent vulvovaginal bacterial infections in women of reproductive age. Postgrad Med J. 2017 May; 93(1099):297. PMID: 28057837.
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    4. Hilbert DW, Smith WL, Paulish-Miller TE, Chadwick SG, Toner G, Mordechai E, Adelson ME, Sobel JD, Gygax SE. Utilization of molecular methods to identify prognostic markers for recurrent bacterial vaginosis. Diagn Microbiol Infect Dis. 2016 Oct; 86(2):231-42. PMID: 27431434.
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    5. Hilbert DW, Smith WL, Chadwick SG, Toner G, Mordechai E, Adelson ME, Aguin TJ, Sobel JD, Gygax SE. Correction for Hilbert et al., Development and Validation of a Highly Accurate Quantitative Real-Time PCR Assay for Diagnosis of Bacterial Vaginosis. J Clin Microbiol. 2016 Jul; 54(7):1930. PMID: 27343296.
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    6. Schlabritz-Loutsevitch N, Gygax SE, Dick E, Smith WL, Snider C, Hubbard G, Ventolini G. Vaginal Dysbiosis from an Evolutionary Perspective. Sci Rep. 2016 May 26; 6:26817. PMID: 27226349.
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    7. Hilbert DW, Smith WL, Chadwick SG, Toner G, Mordechai E, Adelson ME, Aguin TJ, Sobel JD, Gygax SE. Development and Validation of a Highly Accurate Quantitative Real-Time PCR Assay for Diagnosis of Bacterial Vaginosis. J Clin Microbiol. 2016 Apr; 54(4):1017-24. PMID: 26818677; PMCID: PMC4809904.
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    8. Schuyler JA, Mordechai E, Adelson ME, Gygax SE, Hilbert DW. Draft Genome Sequence of a Metronidazole-Resistant Derivative of Gardnerella vaginalis Strain ATCC 14019. Genome Announc. 2015; 3(6). PMID: 26564054.
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    9. Schuyler JA, Mordechai E, Adelson ME, Sobel JD, Gygax SE, Hilbert DW. Identification of intrinsically metronidazole-resistant clades of Gardnerella vaginalis. Diagn Microbiol Infect Dis. 2016 Jan; 84(1):1-3. PMID: 26514076.
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    10. Schuyler JA, Chadwick SG, Mordechai E, Adelson ME, Gygax SE, Hilbert DW. Draft Genome Sequence of a Metronidazole-Resistant Gardnerella vaginalis Isolate. Genome Announc. 2015; 3(5). PMID: 26337887.
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    11. Schuyler JA, Mordechai E, Adelson ME, Gygax SE, Hilbert DW. Draft Genome Sequence of a Metronidazole-Susceptible Atopobium vaginae Isolate. Genome Announc. 2015; 3(5). PMID: 26337886.
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    12. Smith WL, Hedges SR, Mordechai E, Adelson ME, Trama JP, Gygax SE, Kaunitz AM, Hilbert DW. Cervical and vaginal flora specimens are highly concordant with respect to bacterial vaginosis-associated organisms and commensal Lactobacillus species in women of reproductive age. J Clin Microbiol. 2014 Aug; 52(8):3078-81. PMID: 24899020.
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    13. Whaley SG, Caudle KE, Vermitsky JP, Chadwick SG, Toner G, Barker KS, Gygax SE, Rogers PD. UPC2A is required for high-level azole antifungal resistance in Candida glabrata. Antimicrob Agents Chemother. 2014 Aug; 58(8):4543-54. PMID: 24867980.
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    14. Paulish-Miller TE, Augostini P, Schuyler JA, Smith WL, Mordechai E, Adelson ME, Gygax SE, Secor WE, Hilbert DW. Trichomonas vaginalis metronidazole resistance is associated with single nucleotide polymorphisms in the nitroreductase genes ntr4Tv and ntr6Tv. Antimicrob Agents Chemother. 2014 May; 58(5):2938-43. PMID: 24550324.
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    15. Balashov SV, Mordechai E, Adelson ME, Sobel JD, Gygax SE. Multiplex quantitative polymerase chain reaction assay for the identification and quantitation of major vaginal lactobacilli. Diagn Microbiol Infect Dis. 2014 Apr; 78(4):321-7. PMID: 24445159.
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    16. Balashov SV, Mordechai E, Adelson ME, Gygax SE. Identification, quantification and subtyping of Gardnerella vaginalis in noncultured clinical vaginal samples by quantitative PCR. J Med Microbiol. 2014 Feb; 63(Pt 2):162-75. PMID: 24200640.
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    17. Gallo-Ebert C, Donigan M, Stroke IL, Swanson RN, Manners MT, Francisco J, Toner G, Gallagher D, Huang CY, Gygax SE, Webb M, Nickels JT. Novel antifungal drug discovery based on targeting pathways regulating the fungus-conserved Upc2 transcription factor. Antimicrob Agents Chemother. 2014; 58(1):258-66. PMID: 24145546.
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    18. Steier Z, Vermitsky JP, Toner G, Gygax SE, Edlind T, Katiyar S. Flucytosine antagonism of azole activity versus Candida glabrata: role of transcription factor Pdr1 and multidrug transporter Cdr1. Antimicrob Agents Chemother. 2013 Nov; 57(11):5543-7. PMID: 23979762.
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    19. Chadwick SG, Prasad A, Smith WL, Mordechai E, Adelson ME, Gygax SE. Detection of epidemic USA300 community-associated methicillin-resistant Staphylococcus aureus strains by use of a single allele-specific PCR assay targeting a novel polymorphism of Staphylococcus aureus pbp3. J Clin Microbiol. 2013 Aug; 51(8):2541-50. PMID: 23698534.
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    20. Sobel JD, Subramanian C, Foxman B, Fairfax M, Gygax SE. Mixed vaginitis-more than coinfection and with therapeutic implications. Curr Infect Dis Rep. 2013 Apr; 15(2):104-8. PMID: 23354954.
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    21. Chadwick SG, Schuyler JA, Vermitsky JP, Adelson ME, Mordechai E, Gygax SE. X-Plate Technology: a new method for detecting fluconazole resistance in Candida species. J Med Microbiol. 2013 May; 62(Pt 5):720-6. PMID: 23378559.
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    22. Balashov S, Mordechai E, Adelson ME, Gygax SE. Multiplex bead suspension array for screening Neisseria gonorrhoeae antibiotic resistance genetic determinants in noncultured clinical samples. J Mol Diagn. 2013 Jan; 15(1):116-29. PMID: 23159594.
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    23. Flowers SA, Barker KS, Berkow EL, Toner G, Chadwick SG, Gygax SE, Morschhäuser J, Rogers PD. Gain-of-function mutations in UPC2 are a frequent cause of ERG11 upregulation in azole-resistant clinical isolates of Candida albicans. Eukaryot Cell. 2012 Oct; 11(10):1289-99. PMID: 22923048.
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    24. Chadwick SG, Hart CE, Mordechai E, Adelson ME, Gygax SE. Staphylococcal Cassette Chromosome mec type and antibiotic susceptibility profiles of vaginal and nonvaginal MRSA clinical isolates. Diagn Microbiol Infect Dis. 2012 Oct; 74(2):210-2. PMID: 22867728.
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    25. Hilbert DW, Paulish-Miller TE, Tan CK, Carey AJ, Ulett GC, Mordechai E, Adelson ME, Gygax SE, Trama JP. Clinical Escherichia coli isolates utilize alpha-hemolysin to inhibit in vitro epithelial cytokine production. Microbes Infect. 2012 Jul; 14(7-8):628-38. PMID: 22326301.
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    26. Gallo-Ebert C, McCourt PC, Donigan M, Villasmil ML, Chen W, Pandya D, Franco J, Romano D, Chadwick SG, Gygax SE, Nickels JT. Arv1 lipid transporter function is conserved between pathogenic and nonpathogenic fungi. Fungal Genet Biol. 2012 Feb; 49(2):101-13. PMID: 22142782.
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    27. Gygax SE, Vermitsky JP, Chadwick SG, Self MJ, Zimmerman JA, Mordechai E, Adelson ME, Trama JP. Antifungal resistance of Candida glabrata vaginal isolates and development of a quantitative reverse transcription-PCR-based azole susceptibility assay. Antimicrob Agents Chemother. 2008 Sep; 52(9):3424-6. PMID: 18591262.
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    28. Vermitsky JP, Self MJ, Chadwick SG, Trama JP, Adelson ME, Mordechai E, Gygax SE. Survey of vaginal-flora Candida species isolates from women of different age groups by use of species-specific PCR detection. J Clin Microbiol. 2008 Apr; 46(4):1501-3. PMID: 18305136.
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    29. Gygax SE, Schuyler JA, Trama JP, Mordechai E, Adelson ME. Detection of erythromycin and clindamycin resistance genes in Group B Streptococcal clinical isolates and cervicovaginal-rectal swabs. Microb Drug Resist. 2007; 13(2):119-23. PMID: 17650964.
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    30. Vellucci VF, Gygax SE, Hostetter MK. Involvement of Candida albicans pyruvate dehydrogenase complex protein X (Pdx1) in filamentation. Fungal Genet Biol. 2007 Oct; 44(10):979-90. PMID: 17254815.
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    31. Gygax SE, Schuyler JA, Kimmel LE, Trama JP, Mordechai E, Adelson ME. Erythromycin and clindamycin resistance in group B streptococcal clinical isolates. Antimicrob Agents Chemother. 2006 May; 50(5):1875-7. PMID: 16641466.
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    32. Gygax SE, Semighini CP, Goldman GH, Harris SD. SepBCTF4 is required for the formation of DNA-damage-induced UvsCRAD51 foci in Aspergillus nidulans. Genetics. 2005 Mar; 169(3):1391-402. PMID: 15654119.
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