Theodore Tsangaris

TitleProfessor
InstitutionThomas Jefferson University
DepartmentSurgery
Address1015 Walnut St.
Philadelphia PA 19107
Phone215-503-1635
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Howard-McNatt M, Dupont E, Tsangaris T, Garcia-Cantu C, Chiba A, Berger AC, Levine EA, Gass JS, Ollila DW, Chagpar AB. Impact of Cavity Shave Margins on Margin Status in Patients with Pure Ductal Carcinoma in Situ. J Am Coll Surg. 2020 Dec 18. PMID: 33346081.
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    2. Woodward S, Willis A, Lazar M, Berger AC, Tsangaris T. Nipple-sparing mastectomy: A review of outcomes at a single institution. Breast J. 2020 Nov; 26(11):2183-2187. PMID: 33137841.
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    3. Woodward SG, Nimtz K, Hookim K, Sevrukov AB, Tsangaris TN, Willis A, Berger AC, Lazar M. Is radial scar on core needle biopsy a risk factor for malignancy? A single-center retrospective review and implications for management. Breast J. 2020 Jul 13. PMID: 32657492.
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    4. Wang C, Mu Z, Ye Z, Zhang Z, Abu-Khalaf MM, Silver DP, Palazzo JP, Jagannathan G, Fellin FM, Bhattacharya S, Jaslow RJ, Tsangaris TN, Berger A, Neupane M, Cescon TP, Lopez A, Yao K, Chong W, Lu B, Myers RE, Hou L, Wei Q, Li B, Cristofanilli M, Yang H. Prognostic value of HER2 status on circulating tumor cells in advanced-stage breast cancer patients with HER2-negative tumors. Breast Cancer Res Treat. 2020 May 04. PMID: 32367460.
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    5. Tsangaris TN. Comment on "Novel Use of Incisional Negative Pressure Wound Therapy for Management of High-risk Breast Incisions". Ann Surg. 2019 Aug 07. PMID: 31404011.
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    6. Dupont E, Tsangaris T, Garcia-Cantu C, Howard-McNatt M, Chiba A, Berger AC, Levine EA, Gass JS, Gallagher K, Lum SS, Martinez RD, Willis AI, Pandya SV, Brown EA, Fenton A, Mendiola A, Murray M, Solomon NL, Senthil M, Ollila DW, Edmonson D, Lazar M, Namm JP, Li F, Butler M, McGowan NE, Herrera ME, Avitan YP, Yoder B, Walters LL, McPartland T, Chagpar AB. Resection of Cavity Shave Margins in Stage 0-III Breast Cancer Patients Undergoing Breast Conserving Surgery: A Prospective Multicenter Randomized Controlled Trial. Ann Surg. 2019 Jul 08. PMID: 31290763.
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    7. Ye Z, Wang C, Wan S, Mu Z, Zhang Z, Abu-Khalaf MM, Fellin FM, Silver DP, Neupane M, Jaslow RJ, Bhattacharya S, Tsangaris TN, Chervoneva I, Berger A, Austin L, Palazzo JP, Myers RE, Pancholy N, Toorkey D, Yao K, Krall M, Li X, Chen X, Fu X, Xing J, Hou L, Wei Q, Li B, Cristofanilli M, Yang H. Association of clinical outcomes in metastatic breast cancer patients with circulating tumour cell and circulating cell-free DNA. Eur J Cancer. 2019 Jan; 106:133-143. PMID: 30528798.
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    8. Chagpar AB, Tsangaris TN, Lannin DR. Do All Positive Margins in Breast Cancer Patients Undergoing a Partial Mastectomy Need to Be Resected? J Am Coll Surg. 2018 Mar 07. PMID: 29524664.
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    9. Bailey CR, Ogbuagu O, Baltodano PA, Simjee UF, Manahan MA, Cooney DS, Jacobs LK, Tsangaris TN, Cooney CM, Rosson GD. Quality-of-Life Outcomes Improve with Nipple-Sparing Mastectomy and Breast Reconstruction. Plast Reconstr Surg. 2017 Aug; 140(2):219-226. PMID: 28746266.
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    10. Chagpar AB, Horowitz NR, Killelea BK, Tsangaris T, Longley P, Grizzle S, Loftus M, Li F, Butler M, Stavris K, Yao X, Harigopal M, Bossuyt V, Lannin DR, Pusztai L, Davidoff AJ, Gross CP. Economic Impact of Routine Cavity Margins Versus Standard Partial Mastectomy in Breast Cancer Patients: Results of a Randomized Controlled Trial. Ann Surg. 2017 Jan; 265(1):39-44. PMID: 27192352.
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    11. Toss A, Palazzo J, Berger A, Guiles F, Sendecki JA, Simone N, Anne R, Avery T, Jaslow R, Lazar M, Tsangaris T, Cristofanilli M. Clinical-pathological features and treatment modalities associated with recurrence in DCIS and micro-invasive carcinoma: Who to treat more and who to treat less. Breast. 2016 Oct; 29:223-30. PMID: 27506636.
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    12. VandenBussche CJ, Cimino-Mathews A, Park BH, Emens LA, Tsangaris TN, Argani P. Reflex Estrogen Receptor (ER) and Progesterone Receptor (PR) Analysis of Ductal Carcinoma In Situ (DCIS) in Breast Needle Core Biopsy Specimens: An Unnecessary Exercise That Costs the United States $35 Million/y. Am J Surg Pathol. 2016 Aug; 40(8):1090-9. PMID: 27299796.
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    13. Tatarian T, Sokas C, Rufail M, Lazar M, Malhotra S, Palazzo JP, Hsu E, Tsangaris T, Berger AC. Intraductal Papilloma with Benign Pathology on Breast Core Biopsy: To Excise or Not? Ann Surg Oncol. 2016 Aug; 23(8):2501-7. PMID: 26960929.
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    14. VandenBussche CJ, Cimino-Mathews A, Park BH, Emens LA, Tsangaris TN, Argani P. Reflex estrogen receptor/progesterone receptor/human epidermal growth factor receptor 2 (ER/PR/Her2) analysis of breast cancers in needle core biopsy specimens dramatically increases health care costs. Am J Surg Pathol. 2015 Jul; 39(7):939-47. PMID: 25871620.
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    15. Chagpar AB, Killelea BK, Tsangaris TN, Butler M, Stavris K, Li F, Yao X, Bossuyt V, Harigopal M, Lannin DR, Pusztai L, Horowitz NR. A Randomized, Controlled Trial of Cavity Shave Margins in Breast Cancer. N Engl J Med. 2015 Aug 6; 373(6):503-10. PMID: 26028131.
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    16. Chand SN, Blanco FF, Jimbo M, Tsangaris TN, Cristofanilli M, Yeo CJ, Winter JM, Pishvaian MJ, Brody JR. PARP Inhibitors for Chemoprevention-Letter. Cancer Prev Res (Phila). 2014 Nov; 7(11):1170-1. PMID: 25368011.
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    17. Poling JS, Tsangaris TN, Argani P, Cimino-Mathews A. Frozen section evaluation of breast carcinoma sentinel lymph nodes: a retrospective review of 1,940 cases. Breast Cancer Res Treat. 2014 Nov; 148(2):355-61. PMID: 25318925.
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    18. Wiznia LE, Lannin DR, Evans SB, Hofstatter EW, Horowitz NR, Killelea BK, Tsangaris TN, Chagpar AB. The number of lymph nodes dissected in breast cancer patients influences the accuracy of prognosis. Ann Surg Oncol. 2014 Feb; 21(2):389-94. PMID: 24132625.
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    19. Killelea BK, Chagpar AB, Bishop J, Horowitz NR, Christy C, Tsangaris T, Raghu M, Lannin DR. Is there a correlation between breast cancer molecular subtype using receptors as surrogates and mammographic appearance? Ann Surg Oncol. 2013 Oct; 20(10):3247-53. PMID: 23975299.
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    20. Vandenbussche CJ, Khouri N, Sbaity E, Tsangaris TN, Vang R, Tatsas A, Cimino-Mathews A, Argani P. Borderline atypical ductal hyperplasia/low-grade ductal carcinoma in situ on breast needle core biopsy should be managed conservatively. Am J Surg Pathol. 2013 Jun; 37(6):913-23. PMID: 23598968.
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    21. Sue GR, Lannin DR, Killelea B, Tsangaris T, Chagpar AB. Does time to definitive treatment matter in patients with ductal carcinoma in situ? Am Surg. 2013 Jun; 79(6):561-5. PMID: 23711263.
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    22. Stearns V, Jacobs LK, Fackler M, Tsangaris TN, Rudek MA, Higgins M, Lange J, Cheng Z, Slater SA, Jeter SC, Powers P, Briest S, Chao C, Yoshizawa C, Sugar E, Espinoza-Delgado I, Sukumar S, Gabrielson E, Davidson NE. Biomarker modulation following short-term vorinostat in women with newly diagnosed primary breast cancer. Clin Cancer Res. 2013 Jul 15; 19(14):4008-16. PMID: 23719261.
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    23. Stearns V, Mori T, Jacobs LK, Khouri NF, Gabrielson E, Yoshida T, Kominsky SL, Huso DL, Jeter S, Powers P, Tarpinian K, Brown RJ, Lange JR, Rudek MA, Zhang Z, Tsangaris TN, Sukumar S. Preclinical and clinical evaluation of intraductally administered agents in early breast cancer. Sci Transl Med. 2011 Oct 26; 3(106):106ra108. PMID: 22030751.
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    24. Jacobs MA, Stearns V, Wolff AC, Macura K, Argani P, Khouri N, Tsangaris T, Barker PB, Davidson NE, Bhujwalla ZM, Bluemke DA, Ouwerkerk R. Multiparametric magnetic resonance imaging, spectroscopy and multinuclear (²³Na) imaging monitoring of preoperative chemotherapy for locally advanced breast cancer. Acad Radiol. 2010 Dec; 17(12):1477-85. PMID: 20863721.
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    25. Subhawong AP, Subhawong TK, Khouri N, Tsangaris T, Nassar H. Incidental minimal atypical lobular hyperplasia on core needle biopsy: correlation with findings on follow-up excision. Am J Surg Pathol. 2010 Jun; 34(6):822-8. PMID: 20431477.
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    26. Chumsri S, Jeter S, Jacobs LK, Nassar H, Armstrong DK, Emens LA, Fetting JH, Lange JR, Riley C, Tsangaris TN, Wolff AC, Zellars R, Zhang Z, Stearns V. Pathologic complete response to preoperative sequential doxorubicin/cyclophosphamide and single-agent taxane with or without trastuzumab in stage II/III HER2-positive breast cancer. Clin Breast Cancer. 2010 Feb; 10(1):40-5. PMID: 20133257.
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    27. Zhou J, Trock B, Tsangaris TN, Friedman NB, Shapiro D, Brotzman M, Chan-Li Y, Chan DW, Li J. A unique proteolytic fragment of alpha1-antitrypsin is elevated in ductal fluid of breast cancer patient. Breast Cancer Res Treat. 2010 Aug; 123(1):73-86. PMID: 19902353.
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    28. Bevers TB, Anderson BO, Bonaccio E, Buys S, Buys S, Daly MB, Dempsey PJ, Farrar WB, Fleming I, Garber JE, Harris RE, Heerdt AS, Helvie M, Huff JG, Khakpour N, Khan SA, Krontiras H, Lyman G, Rafferty E, Shaw S, Smith ML, Tsangaris TN, Williams C, Yankeelov T, Yaneeklov T. NCCN clinical practice guidelines in oncology: breast cancer screening and diagnosis. J Natl Compr Canc Netw. 2009 Nov; 7(10):1060-96. PMID: 19930975.
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    29. Balmanoukian A, Zhang Z, Jeter S, Slater S, Armstrong DK, Emens LA, Fetting JH, Wolff AC, Davidson NE, Jacobs L, Lange J, Tsangaris TN, Zellars R, Gabrielson E, Stearns V. African American women who receive primary anthracycline- and taxane-based chemotherapy for triple-negative breast cancer suffer worse outcomes compared with white women. J Clin Oncol. 2009 Aug 1; 27(22):e35-7; author reply e38-9. PMID: 19564528.
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    30. Zellars RC, Stearns V, Frassica D, Asrari F, Tsangaris T, Myers L, DiPasquale S, Lange JR, Jacobs LK, Emens LA, Armstrong DK, Fetting JH, Garrett-Mayer E, Davidson NE, Wolff AC. Feasibility trial of partial breast irradiation with concurrent dose-dense doxorubicin and cyclophosphamide in early-stage breast cancer. J Clin Oncol. 2009 Jun 10; 27(17):2816-22. PMID: 19332718.
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    31. Voltura AM, Tsangaris TN, Rosson GD, Jacobs LK, Flores JI, Singh NK, Argani P, Balch CM. Nipple-sparing mastectomy: critical assessment of 51 procedures and implications for selection criteria. Ann Surg Oncol. 2008 Dec; 15(12):3396-401. PMID: 18923874.
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    32. Cao D, Tsangaris TN, Kouprina N, Wu LS, Balch CM, Vang R, Argani P. The superficial margin of the skin-sparing mastectomy for breast carcinoma: factors predicting involvement and efficacy of additional margin sampling. Ann Surg Oncol. 2008 May; 15(5):1330-40. PMID: 18246402.
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    33. Cooney CS, Khouri NF, Tsangaris TN. The role of breast MRI in the management of patients with breast disease. Adv Surg. 2008; 42:299-312. PMID: 18953825.
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    34. Jain A, Haisfield-Wolfe ME, Lange J, Ahuja N, Khouri N, Tsangaris T, Zhang Z, Balch C, Jacobs LK. The role of ultrasound-guided fine-needle aspiration of axillary nodes in the staging of breast cancer. Ann Surg Oncol. 2008 Feb; 15(2):462-71. PMID: 17985188.
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    35. Bevers TB, Anderson BO, Bonaccio E, Borgen PI, Buys S, Daly MB, Dempsey PJ, Farrar WB, Fleming I, Garber JE, Harris RE, Helvie M, Hoover S, Krontiras H, Shaw S, Singletary E, Sugg Skinner C, Smith ML, Tsangaris TN, Wiley EL, Williams C. Breast cancer screening and diagnosis. J Natl Compr Canc Netw. 2006 May; 4(5):480-508. PMID: 16687096.
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    36. Nahabedian MY, Tsangaris TN. Breast reconstruction following subcutaneous mastectomy for cancer: a critical appraisal of the nipple-areola complex. Plast Reconstr Surg. 2006 Apr; 117(4):1083-90. PMID: 16582769.
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    37. Cao D, Lin C, Woo SH, Vang R, Tsangaris TN, Argani P. Separate cavity margin sampling at the time of initial breast lumpectomy significantly reduces the need for reexcisions. Am J Surg Pathol. 2005 Dec; 29(12):1625-32. PMID: 16327435.
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    38. Nahabedian MY, Tsangaris T, Momen B. Breast reconstruction with the DIEP flap or the muscle-sparing (MS-2) free TRAM flap: is there a difference? Plast Reconstr Surg. 2005 Feb; 115(2):436-44; discussion 445-6. PMID: 15692347.
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    39. Schwartz MD, Lerman C, Brogan B, Peshkin BN, Halbert CH, DeMarco T, Lawrence W, Main D, Finch C, Magnant C, Pennanen M, Tsangaris T, Willey S, Isaacs C. Impact of BRCA1/BRCA2 counseling and testing on newly diagnosed breast cancer patients. J Clin Oncol. 2004 May 15; 22(10):1823-9. PMID: 15067026.
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    40. Nahabedian MY, Tsangaris T, Momen B, Manson PN. Infectious complications following breast reconstruction with expanders and implants. Plast Reconstr Surg. 2003 Aug; 112(2):467-76. PMID: 12900604.
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    41. Frassica DA, Bajaj GK, Tsangaris TN. Treatment of complications after breast-conservation therapy. Oncology (Williston Park). 2003 Aug; 17(8):1118-28; discussion 1131-6, 1141. PMID: 12966679.
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    42. Spear SL, Pelletiere CV, Wolfe AJ, Tsangaris TN, Pennanen MF. Experience with reduction mammaplasty combined with breast conservation therapy in the treatment of breast cancer. Plast Reconstr Surg. 2003 Mar; 111(3):1102-9. PMID: 12621180.
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    43. Mandelblatt JS, Edge SB, Meropol NJ, Senie R, Tsangaris T, Grey L, Peterson BM, Hwang YT, Kerner J, Weeks J. Predictors of long-term outcomes in older breast cancer survivors: perceptions versus patterns of care. J Clin Oncol. 2003 Mar 1; 21(5):855-63. PMID: 12610185.
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    44. Stearns V, Singh B, Tsangaris T, Crawford JG, Novielli A, Ellis MJ, Isaacs C, Pennanen M, Tibery C, Farhad A, Slack R, Hayes DF. A prospective randomized pilot study to evaluate predictors of response in serial core biopsies to single agent neoadjuvant doxorubicin or paclitaxel for patients with locally advanced breast cancer. Clin Cancer Res. 2003 Jan; 9(1):124-33. PMID: 12538460.
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    45. Mandelblatt JS, Edge SB, Meropol NJ, Senie R, Tsangaris T, Grey L, Peterson B, Hwang YT, Weeks JC. Sequelae of axillary lymph node dissection in older women with stage 1 and 2 breast carcinoma. Cancer. 2002 Dec 15; 95(12):2445-54. PMID: 12467056.
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    46. Edge SB, Gold K, Berg CD, Meropol NJ, Tsangaris TN, Gray L, Petersen BM, Hwang YT, Mandelblatt JS. Patient and provider characteristics that affect the use of axillary dissection in older women with stage I-II breast carcinoma. Cancer. 2002 May 15; 94(10):2534-41. PMID: 12173318.
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    47. Ellis M, Davis N, Coop A, Liu M, Schumaker L, Lee RY, Srikanchana R, Russell CG, Singh B, Miller WR, Stearns V, Pennanen M, Tsangaris T, Gallagher A, Liu A, Zwart A, Hayes DF, Lippman ME, Wang Y, Clarke R. Development and validation of a method for using breast core needle biopsies for gene expression microarray analyses. Clin Cancer Res. 2002 May; 8(5):1155-66. PMID: 12006532.
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    48. Stearns V, Ewing CA, Slack R, Penannen MF, Hayes DF, Tsangaris TN. Sentinel lymphadenectomy after neoadjuvant chemotherapy for breast cancer may reliably represent the axilla except for inflammatory breast cancer. Ann Surg Oncol. 2002 Apr; 9(3):235-42. PMID: 11923129.
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    49. Fernandez PM, Tabbara SO, Jacobs LK, Manning FC, Tsangaris TN, Schwartz AM, Kennedy KA, Patierno SR. Overexpression of the glucose-regulated stress gene GRP78 in malignant but not benign human breast lesions. Breast Cancer Res Treat. 2000 Jan; 59(1):15-26. PMID: 10752676.
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    50. Tsangaris TN, Trad K, Brody FJ, Jacobs LK, Tsangaris NT, Sackier JM. Endoscopic axillary exploration and sentinel lymphadenectomy. Surg Endosc. 1999 Jan; 13(1):43-7. PMID: 9869687.
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    51. Stomper PC, Mazurchuk RV, Tsangaris TN. Breast MRI as an adjunct in the diagnosis of a carcinoma partially obscured on mammography. Clin Imaging. 1994 Jul-Sep; 18(3):195-8. PMID: 7922840.
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    52. Carson W, Sanchez-Forgach E, Stomper P, Penetrante R, Tsangaris TN, Edge SB. Lobular carcinoma in situ: observation without surgery as an appropriate therapy. Ann Surg Oncol. 1994 Mar; 1(2):141-6. PMID: 7834439.
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    53. Stomper PC, Cholewinski SP, Penetrante RB, Harlos JP, Tsangaris TN. Atypical hyperplasia: frequency and mammographic and pathologic relationships in excisional biopsies guided with mammography and clinical examination. Radiology. 1993 Dec; 189(3):667-71. PMID: 8234688.
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    54. Stomper PC, Tsangaris TN. CT of pectoralis muscle invasion by breast carcinoma. J Comput Assist Tomogr. 1993 Sep-Oct; 17(5):829-31. PMID: 8396601.
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    55. Palmer ML, Tsangaris TN. Breast biopsy in women 30 years old or less. Am J Surg. 1993 Jun; 165(6):708-12. PMID: 8506971.
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    56. Cajucom CC, Tsangaris TN, Nemoto T, Driscoll D, Penetrante RB, Holyoke ED. Results of salvage mastectomy for local recurrence after breast-conserving surgery without radiation therapy. Cancer. 1993 Mar 1; 71(5):1774-9. PMID: 8448741.
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    57. Mamounas EP, Perez-Mesa C, Penetrante RB, Driscoll DL, Blumenson LE, Tsangaris TN. Patterns of occurrence of second primary non-mammary malignancies in breast cancer patients: results from 1382 consecutive autopsies. Surg Oncol. 1993; 2(3):175-85. PMID: 8252207.
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    58. Stomper PC, Stewart CC, Penetrante RB, Nava ME, Tsangaris TN. Flow cytometric DNA analysis of excised breast lesions: use of fresh tissue needle aspirates obtained under guidance with mammography of the specimen. Radiology. 1992 Nov; 185(2):415-22. PMID: 1329141.
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    59. Sanchez-Forgach ER, Mamounas EP, Warneke J, Driscoll D, Blumenson LE, Tsangaris TN. Factors affecting outcome in locally advanced breast cancer. Surg Oncol. 1992 Oct; 1(5):347-55. PMID: 1341270.
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    60. Tsangaris TN, Knox SM, Cheek JH. Tumor hormone receptor status and recurrences in premenopausal patients with node-negative breast carcinoma. Cancer. 1992 Feb 15; 69(4):984-7. PMID: 1735091.
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