Protein Synthesis Inhibitors
"Protein Synthesis Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds which inhibit the synthesis of proteins. They are usually ANTI-BACTERIAL AGENTS or toxins. Mechanism of the action of inhibition includes the interruption of peptide-chain elongation, the blocking the A site of ribosomes, the misreading of the genetic code or the prevention of the attachment of oligosaccharide side chains to glycoproteins.
| Descriptor ID |
D011500
|
| MeSH Number(s) |
D27.505.519.389.760
|
| Concept/Terms |
Protein Synthesis Inhibitors- Protein Synthesis Inhibitors
- Inhibitors, Protein Synthesis
- Protein Synthesis Antagonists
- Antagonists, Protein Synthesis
|
Below are MeSH descriptors whose meaning is more general than "Protein Synthesis Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Protein Synthesis Inhibitors".
This graph shows the total number of publications written about "Protein Synthesis Inhibitors" by people in this website by year, and whether "Protein Synthesis Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 1 | 2 |
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 6 | 6 |
| 2004 | 2 | 1 | 3 |
| 2005 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
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Below are the most recent publications written about "Protein Synthesis Inhibitors" by people in Profiles.
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Pucci MJ, Bush K. Investigational antimicrobial agents of 2013. Clin Microbiol Rev. 2013 Oct; 26(4):792-821.
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Abbas T, Mueller AC, Shibata E, Keaton M, Rossi M, Dutta A. CRL1-FBXO11 promotes Cdt2 ubiquitylation and degradation and regulates Pr-Set7/Set8-mediated cellular migration. Mol Cell. 2013 Mar 28; 49(6):1147-58.
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Bush K, Pucci MJ. New antimicrobial agents on the horizon. Biochem Pharmacol. 2011 Dec 1; 82(11):1528-39.
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G?ller M, Toualbi-Abed K, Legrand A, Michel L, Mauviel A, Bernuau D, Daniel F. c-Fos overexpression increases the proliferation of human hepatocytes by stabilizing nuclear Cyclin D1. World J Gastroenterol. 2008 Nov 07; 14(41):6339-46.
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Tacheau C, Michel L, Farge D, Mauviel A, Verrecchia F. Involvement of ERK signaling in halofuginone-driven inhibition of fibroblast ability to contract collagen lattices. Eur J Pharmacol. 2007 Nov 14; 573(1-3):65-9.
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Sandorfi N, Louneva N, Hitraya E, Hajnoczky G, Saitta B, Jimenez SA. Inhibition of collagen gene expression in systemic sclerosis dermal fibroblasts by mithramycin. Ann Rheum Dis. 2005 Dec; 64(12):1685-91.
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Suon S, Jin H, Donaldson AE, Caterson EJ, Tuan RS, Deschennes G, Marshall C, Iacovitti L. Transient differentiation of adult human bone marrow cells into neuron-like cells in culture: development of morphological and biochemical traits is mediated by different molecular mechanisms. Stem Cells Dev. 2004 Dec; 13(6):625-35.
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Fiscella RG, Lai WW, Buerk B, Khan M, Rodvold KA, Pulido JS, Labib S, Shapiro MJ, Blair NP. Aqueous and vitreous penetration of linezolid (Zyvox) after oral administration. Ophthalmology. 2004 Jun; 111(6):1191-5.
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Xavier S, Piek E, Fujii M, Javelaud D, Mauviel A, Flanders KC, Samuni AM, Felici A, Reiss M, Yarkoni S, Sowers A, Mitchell JB, Roberts AB, Russo A. Amelioration of radiation-induced fibrosis: inhibition of transforming growth factor-beta signaling by halofuginone. J Biol Chem. 2004 Apr 09; 279(15):15167-76.
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Tafani M, Cohn JA, Karpinich NO, Rothman RJ, Russo MA, Farber JL. Regulation of intracellular pH mediates Bax activation in HeLa cells treated with staurosporine or tumor necrosis factor-alpha. J Biol Chem. 2002 Dec 20; 277(51):49569-76.