Protein-Tyrosine Kinases

"Protein-Tyrosine Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Protein kinases that catalyze the PHOSPHORYLATION of TYROSINE residues in proteins with ATP or other nucleotides as phosphate donors.

Descriptor ID	D011505
MeSH Number(s)	D08.811.913.696.620.682.725
Concept/Terms	Protein-Tyrosine Kinases Protein-Tyrosine Kinases Kinases, Protein-Tyrosine Protein Tyrosine Kinases Tyrosine Kinase Kinase, Tyrosine Tyrosine Protein Kinase Kinase, Tyrosine Protein Tyrosylprotein Kinase Kinase, Tyrosylprotein Tyrosine-Specific Protein Kinase Kinase, Tyrosine-Specific Protein Protein Kinase, Tyrosine-Specific Tyrosine Specific Protein Kinase Tyrosine-Specific Protein Kinases Kinases, Tyrosine-Specific Protein Protein Kinases, Tyrosine-Specific Tyrosine Specific Protein Kinases Protein-Tyrosine Kinase Kinase, Protein-Tyrosine Protein Tyrosine Kinase Tyrosine Protein Kinases Kinases, Tyrosine Protein Protein Kinases, Tyrosine

Below are MeSH descriptors whose meaning is more general than "Protein-Tyrosine Kinases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
Phosphotransferases [D08.811.913.696]
Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
Protein Kinases [D08.811.913.696.620.682]
Protein-Tyrosine Kinases [D08.811.913.696.620.682.725]

Below are MeSH descriptors whose meaning is related to "Protein-Tyrosine Kinases".

Below are MeSH descriptors whose meaning is more specific than "Protein-Tyrosine Kinases".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Protein-Tyrosine Kinases" by people in this website by year, and whether "Protein-Tyrosine Kinases" was a major or minor topic of these publications.

Bar chart showing 165 publications over 28 distinct years, with a maximum of 16 publications in 2004

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	4	3	7
1997	4	5	9
1998	4	4	8
1999	4	5	9
2000	6	2	8
2001	1	3	4
2002	8	7	15
2003	4	7	11
2004	4	12	16
2005	0	4	4
2006	1	4	5
2007	4	5	9
2008	1	3	4
2009	2	2	4
2010	3	2	5
2011	2	1	3
2012	1	2	3
2013	3	1	4
2014	3	3	6
2015	2	2	4
2016	3	6	9
2017	1	3	4
2018	1	2	3
2019	1	0	1
2020	2	1	3
2021	1	1	2
2022	0	3	3
2023	0	2	2

Below are the most recent publications written about "Protein-Tyrosine Kinases" by people in Profiles.

Wood ML, Fanburg-Smith JC, Brian JM, White JC, Powell JL, Freiberg AS. Successful Crizotinib-targeted Therapy of Pediatric Unresectable ERC1::ALK Fusion Sarcoma. J Pediatr Hematol Oncol. 2024 03 01; 46(2):e184-e187.

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Gates JC, Clark AP, Cherkas E, Shreenivas AV, Kraus D, Danzinger N, Huang RSP, Johnson J, Ross JS. Genomic profiling and precision medicine in complex ameloblastoma. Head Neck. 2023 04; 45(4):816-826.

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Hernandez-Lara MA, Yadav SK, Shah SD, Okumura M, Yokoyama Y, Penn RB, Kambayashi T, Deshpande DA. Regulation of Airway Smooth Muscle Cell Proliferation by Diacylglycerol Kinase: Relevance to Airway Remodeling in Asthma. Int J Mol Sci. 2022 Oct 06; 23(19).

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Wei S, Talarchek JN, Huang M, Gong Y, Du F, Ehya H, Flieder DB, Patchefsky AS, Wasik MA, Pei J. Cell block-based RNA next generation sequencing for detection of gene fusions in lung adenocarcinoma: An institutional experience. Cytopathology. 2023 Jan; 34(1):28-34.

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Neill T, Xie C, Iozzo RV. Decorin evokes reversible mitochondrial depolarization in carcinoma and vascular endothelial cells. Am J Physiol Cell Physiol. 2022 11 01; 323(5):C1355-C1373.

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Sato K, Padgaonkar AA, Baker SJ, Cosenza SC, Rechkoblit O, Subbaiah DRCV, Domingo-Domenech J, Bartkowski A, Port ER, Aggarwal AK, Ramana Reddy MV, Irie HY, Reddy EP. Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem cells and chemotherapy-resistant disease. Nat Commun. 2021 08 03; 12(1):4671.

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Mendoza FA, Piera-Velazquez S, Jimenez SA. Tyrosine kinases in the pathogenesis of tissue fibrosis in systemic sclerosis and potential therapeutic role of their inhibition. Transl Res. 2021 05; 231:139-158.

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Agostini LC, Jain A, Shupp A, Nevler A, McCarthy G, Bussard KM, Yeo CJ, Brody JR. Combined Targeting of PARG and Wee1 Causes Decreased Cell Survival and DNA Damage in an S-Phase-Dependent Manner. Mol Cancer Res. 2021 02; 19(2):207-214.

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Tripathi R, Liu Z, Jain A, Lyon A, Meeks C, Richards D, Liu J, He D, Wang C, Nespi M, Rymar A, Wang P, Wilson M, Plattner R. Combating acquired resistance to MAPK inhibitors in melanoma by targeting Abl1/2-mediated reactivation of MEK/ERK/MYC signaling. Nat Commun. 2020 10 29; 11(1):5463.

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Paris AJ, Hayer KE, Oved JH, Avgousti DC, Toulmin SA, Zepp JA, Zacharias WJ, Katzen JB, Basil MC, Kremp MM, Slamowitz AR, Jayachandran S, Sivakumar A, Dai N, Wang P, Frank DB, Eisenlohr LC, Cantu E, Beers MF, Weitzman MD, Morrisey EE, Worthen GS. STAT3-BDNF-TrkB signalling promotes alveolar epithelial regeneration after lung injury. Nat Cell Biol. 2020 10; 22(10):1197-1210.

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