Purine-Nucleoside Phosphorylase
"Purine-Nucleoside Phosphorylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the reaction between a purine nucleoside and orthophosphate to form a free purine plus ribose-5-phosphate. EC 2.4.2.1.
| Descriptor ID |
D011683
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| MeSH Number(s) |
D08.811.913.400.725.800
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| Concept/Terms |
Purine-Nucleoside Phosphorylase- Purine-Nucleoside Phosphorylase
- Phosphorylase, Purine-Nucleoside
- Purine Nucleoside Phosphorylase
- Inosine Phosphorylase
- Phosphorylase, Inosine
- Purine Nucleoside Phosphorylases
- Nucleoside Phosphorylases, Purine
- Phosphorylases, Purine Nucleoside
|
Below are MeSH descriptors whose meaning is more general than "Purine-Nucleoside Phosphorylase".
Below are MeSH descriptors whose meaning is more specific than "Purine-Nucleoside Phosphorylase".
This graph shows the total number of publications written about "Purine-Nucleoside Phosphorylase" by people in this website by year, and whether "Purine-Nucleoside Phosphorylase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2005 | 2 | 0 | 2 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Purine-Nucleoside Phosphorylase" by people in Profiles.
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Barrett MT, Deiotte R, Lenkiewicz E, Malasi S, Holley T, Evers L, Posner RG, Jones T, Han H, Sausen M, Velculescu VE, Drebin J, O'Dwyer P, Jameson G, Ramanathan RK, Von Hoff DD. Clinical study of genomic drivers in pancreatic ductal adenocarcinoma. Br J Cancer. 2017 Aug 08; 117(4):572-582.
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Hustinx SR, Leoni LM, Yeo CJ, Brown PN, Goggins M, Kern SE, Hruban RH, Maitra A. Concordant loss of MTAP and p16/CDKN2A expression in pancreatic intraepithelial neoplasia: evidence of homozygous deletion in a noninvasive precursor lesion. Mod Pathol. 2005 Jul; 18(7):959-63.
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Hustinx SR, Hruban RH, Leoni LM, Iacobuzio-Donahue C, Cameron JL, Yeo CJ, Brown PN, Argani P, Ashfaq R, Fukushima N, Goggins M, Kern SE, Maitra A. Homozygous deletion of the MTAP gene in invasive adenocarcinoma of the pancreas and in periampullary cancer: a potential new target for therapy. Cancer Biol Ther. 2005 Jan; 4(1):83-6.
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Subhi AL, Tang B, Balsara BR, Altomare DA, Testa JR, Cooper HS, Hoffman JP, Meropol NJ, Kruger WD. Loss of methylthioadenosine phosphorylase and elevated ornithine decarboxylase is common in pancreatic cancer. Clin Cancer Res. 2004 Nov 01; 10(21):7290-6.