"Relapsing Fever" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An acute infection characterized by recurrent episodes of PYREXIA alternating with asymptomatic intervals of apparent recovery. This condition is caused by SPIROCHETES of the genus BORRELIA. It is transmitted by the BITES of either the body louse (PEDICULUS humanus corporis), for which humans are the reservoir, or by soft ticks of the genus ORNITHODOROS, for which rodents and other animals are the principal reservoirs.
Descriptor ID |
D012061
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MeSH Number(s) |
C01.252.400.155.644 C01.252.400.825.750 C01.252.847.193.644
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Concept/Terms |
Relapsing Fever- Relapsing Fever
- Fever, Relapsing
- Fevers, Relapsing
- Relapsing Fevers
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Below are MeSH descriptors whose meaning is more general than "Relapsing Fever".
Below are MeSH descriptors whose meaning is more specific than "Relapsing Fever".
This graph shows the total number of publications written about "Relapsing Fever" by people in this website by year, and whether "Relapsing Fever" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 0 | 1 | 1 |
2001 | 1 | 0 | 1 |
2003 | 1 | 1 | 2 |
2009 | 1 | 0 | 1 |
2010 | 2 | 0 | 2 |
2011 | 1 | 0 | 1 |
2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Relapsing Fever" by people in Profiles.
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Cheng M, Xu J, Ding K, Zhang J, Lu W, Liu J, Gao J, Alugupalli KR, Liu H. Attenuation of relapsing fever neuroborreliosis in mice by IL-17A blockade. Proc Natl Acad Sci U S A. 2022 10 18; 119(42):e2205460119.
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Vuyyuru R, Liu H, Manser T, Alugupalli KR. Characteristics of Borrelia hermsii infection in human hematopoietic stem cell-engrafted mice mirror those of human relapsing fever. Proc Natl Acad Sci U S A. 2011 Dec 20; 108(51):20707-12.
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Dickinson GS, Piccone H, Sun G, Lien E, Gatto L, Alugupalli KR. Toll-like receptor 2 deficiency results in impaired antibody responses and septic shock during Borrelia hermsii infection. Infect Immun. 2010 Nov; 78(11):4579-88.
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Liu H, Fitzgerald D, Gran B, Leong JM, Alugupalli KR. Induction of distinct neurologic disease manifestations during relapsing fever requires T lymphocytes. J Immunol. 2010 May 15; 184(10):5859-64.
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Benoit VM, Petrich A, Alugupalli KR, Marty-Roix R, Moter A, Leong JM, Boyartchuk VL. Genetic control of the innate immune response to Borrelia hermsii influences the course of relapsing fever in inbred strains of mice. Infect Immun. 2010 Feb; 78(2):586-94.
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Alugupalli KR, Michelson AD, Joris I, Schwan TG, Hodivala-Dilke K, Hynes RO, Leong JM. Spirochete-platelet attachment and thrombocytopenia in murine relapsing fever borreliosis. Blood. 2003 Oct 15; 102(8):2843-50.
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Alugupalli KR, Gerstein RM, Chen J, Szomolanyi-Tsuda E, Woodland RT, Leong JM. The resolution of relapsing fever borreliosis requires IgM and is concurrent with expansion of B1b lymphocytes. J Immunol. 2003 Apr 1; 170(7):3819-27.
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Alugupalli KR, Michelson AD, Barnard MR, Robbins D, Coburn J, Baker EK, Ginsberg MH, Schwan TG, Leong JM. Platelet activation by a relapsing fever spirochaete results in enhanced bacterium-platelet interaction via integrin alphaIIbbeta3 activation. Mol Microbiol. 2001 Jan; 39(2):330-40.
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Magoun L, Zückert WR, Robbins D, Parveen N, Alugupalli KR, Schwan TG, Barbour AG, Leong JM. Variable small protein (Vsp)-dependent and Vsp-independent pathways for glycosaminoglycan recognition by relapsing fever spirochaetes. Mol Microbiol. 2000 May; 36(4):886-97.