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Structural basis for DNA damage-dependent poly(ADP-ribosyl)ation by human PARP-1.
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Structural basis for DNA damage-dependent poly(ADP-ribosyl)ation by human PARP-1.
Langelier MF, Planck JL, Roy S, Pascal JM. Structural basis for DNA damage-dependent poly(ADP-ribosyl)ation by human PARP-1. Science. 2012 May 11; 336(6082):728-32.
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PubMed
subject areas
Catalytic Domain
Crystallography, X-Ray
DNA
DNA Breaks, Double-Stranded
Enzyme Stability
Humans
Hydrophobic and Hydrophilic Interactions
Models, Molecular
Nucleic Acid Conformation
Poly Adenosine Diphosphate Ribose
Poly(ADP-ribose) Polymerases
Protein Binding
Protein Conformation
Protein Structure, Tertiary
authors with profiles
John Pascal