"Renin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.
| Descriptor ID |
D012083
|
| MeSH Number(s) |
D08.811.277.656.074.500.780 D08.811.277.656.300.048.780 D08.811.277.656.837.750
|
| Concept/Terms |
Renin- Renin
- Angiotensin-Forming Enzyme
- Angiotensin Forming Enzyme
- Angiotensinogenase
Prorenin- Prorenin
- Inactive Renin
- Renin, Inactive
- Big Renin
- Renin, Big
- Cryorenin
|
Below are MeSH descriptors whose meaning is more general than "Renin".
Below are MeSH descriptors whose meaning is more specific than "Renin".
This graph shows the total number of publications written about "Renin" by people in this website by year, and whether "Renin" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 3 | 4 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Renin" by people in Profiles.
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Maser RE, Lenhard MJ, Kolm P, Edwards DG. Direct renin inhibition improves parasympathetic function in diabetes. Diabetes Obes Metab. 2013 Jan; 15(1):28-34.
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Huan Y, Deloach S, Keith SW, Goodfriend TL, Falkner B. Aldosterone and aldosterone: renin ratio associations with insulin resistance and blood pressure in African Americans. J Am Soc Hypertens. 2012 Jan-Feb; 6(1):56-65.
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Wenner MM, Edwards DG, Ray CA, Rose WC, Gardner TJ, Stillabower M, Farquhar WB. Celecoxib does not alter cardiovascular and renal function during dietary salt loading. Clin Exp Pharmacol Physiol. 2011 Aug; 38(8):543-9.
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Chamarthi B, Williams GH, Ricchiuti V, Srikumar N, Hopkins PN, Luther JM, Jeunemaitre X, Thomas A. Inflammation and hypertension: the interplay of interleukin-6, dietary sodium, and the renin-angiotensin system in humans. Am J Hypertens. 2011 Oct; 24(10):1143-8.
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Quillo AR, Grant CS, Thompson GB, Farley DR, Richards ML, Young WF. Primary aldosteronism: results of adrenalectomy for nonsingle adenoma. J Am Coll Surg. 2011 Jul; 213(1):106-12; discussion 112-3.
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Bergset J, Storozynsky E, Bisognano JD. Renin inhibition for hypertension: selecting the right role for a new class of drug. Am J Ther. 2010 Mar-Apr; 17(2):182-7.
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Sanoski CA. Aliskiren: an oral direct renin inhibitor for the treatment of hypertension. Pharmacotherapy. 2009 Feb; 29(2):193-212.
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Davis ME, Pemberton CJ, Yandle TG, Fisher SF, Lainchbury JG, Frampton CM, Rademaker MT, Richards AM. Urocortin 2 infusion in healthy humans: hemodynamic, neurohormonal, and renal responses. J Am Coll Cardiol. 2007 Jan 30; 49(4):461-71.
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Thompson WR, Binder-Macleod SA. Association of genetic factors with selected measures of physical performance. Phys Ther. 2006 Apr; 86(4):585-91.
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Liao WC, Vesterqvist O, Delaney C, Jemal M, Ferreira I, Ford N, Swanson B, Uderman H. Pharmacokinetics and pharmacodynamics of the vasopeptidase inhibitor, omapatrilat in healthy subjects. Br J Clin Pharmacol. 2003 Oct; 56(4):395-406.