Thomas Jefferson University

Gerald Grunwald

TitleDean College Life Sciences
InstitutionThomas Jefferson University
DepartmentAdministration - Thomas Jefferson University
Address1020 Locust Street
Philadelphia PA 19107
Phone2155034191
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    R01EY006658     (GRUNWALD, GERALD B)Aug 1, 1986 - Feb 28, 2007
    NIH
    Cell Adhesion in Retinal Development and Pathology
    Role: Principal Investigator
    T32ES007282     (GRUNWALD, GERALD B)Jul 1, 1993 - Jun 30, 2010
    NIH
    Cellular and Molecular Determinants of Birth Defects
    Role: Principal Investigator
    R01EY010965     (GRUNWALD, GERALD B)Mar 1, 1995 - Mar 28, 1999
    NIH
    CADHERIN FUNCTION IN LENS DEVELOPMENT
    Role: Principal Investigator
    R13CA102013     (GRUNWALD, GERALD B)May 1, 2003 - Apr 30, 2008
    NIH
    Gordon Research Conference On Cell Contact And Adhesion
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Grunwald GB. A century of cell adhesion: from the blastomere to the clinic part 1: conceptual and experimental foundations and the pre-molecular era. Cell Commun Adhes. 2013 Dec; 20(6):127-38. PMID: 24245995.
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    2. Adijanto J, Castorino JJ, Wang ZX, Maminishkis A, Grunwald GB, Philp NJ. Microphthalmia-associated transcription factor (MITF) promotes differentiation of human retinal pigment epithelium (RPE) by regulating microRNAs-204/211 expression. J Biol Chem. 2012 Jun 08; 287(24):20491-503. PMID: 22523078.
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    3. Gallagher-Colombo S, Maminishkis A, Tate S, Grunwald GB, Philp NJ. Modulation of MCT3 expression during wound healing of the retinal pigment epithelium. Invest Ophthalmol Vis Sci. 2010 Oct; 51(10):5343-50. PMID: 20505202.
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    4. Pratt CH, Vadigepalli R, Chakravarthula P, Gonye GE, Philp NJ, Grunwald GB. Transcriptional regulatory network analysis during epithelial-mesenchymal transformation of retinal pigment epithelium. Mol Vis. 2008 Aug 04; 14:1414-28. PMID: 18682805.
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    5. Prozialeck WC, Grunwald GB, Dey PM, Reuhl KR, Parrish AR. Cadherins and NCAM as potential targets in metal toxicity. Toxicol Appl Pharmacol. 2002 Aug 01; 182(3):255-65. PMID: 12183105.
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    6. Leong L, Menko AS, Grunwald GB. Differential expression of N- and B-cadherin during lens development. Invest Ophthalmol Vis Sci. 2000 Oct; 41(11):3503-10. PMID: 11006245.
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    7. Ferreira-Cornwell MC, Veneziale RW, Grunwald GB, Menko AS. N-cadherin function is required for differentiation-dependent cytoskeletal reorganization in lens cells in vitro. Exp Cell Res. 2000 Apr 10; 256(1):237-47. PMID: 10739670.
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    8. Pittack C, Grunwald GB, Reh TA. Fibroblast growth factors are necessary for neural retina but not pigmented epithelium differentiation in chick embryos. Development. 1997 Feb; 124(4):805-16. PMID: 9043062.
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    9. Lee MM, Fink BD, Grunwald GB. Evidence that tyrosine phosphorylation regulates N-cadherin turnover during retinal development. Dev Genet. 1997; 20(3):224-34. PMID: 9216062.
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    10. Riehl R, Johnson K, Bradley R, Grunwald GB, Cornel E, Lilienbaum A, Holt CE. Cadherin function is required for axon outgrowth in retinal ganglion cells in vivo. Neuron. 1996 Nov; 17(5):837-48. PMID: 8938117.
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    11. Bixby JL, Grunwald GB, Bookman RJ. Ca2+ influx and neurite growth in response to purified N-cadherin and laminin. J Cell Biol. 1994 Dec; 127(5):1461-75. PMID: 7962102.
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    12. Grunwald GB. The structural and functional analysis of cadherin calcium-dependent cell adhesion molecules. Curr Opin Cell Biol. 1993 Oct; 5(5):797-805. PMID: 8240823.
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    13. Paradies NE, Grunwald GB. Purification and characterization of NCAD90, a soluble endogenous form of N-cadherin, which is generated by proteolysis during retinal development and retains adhesive and neurite-promoting function. J Neurosci Res. 1993 Sep 01; 36(1):33-45. PMID: 8230319.
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    14. Shih DT, Edelman JM, Horwitz AF, Grunwald GB, Buck CA. Structure/function analysis of the integrin beta 1 subunit by epitope mapping. J Cell Biol. 1993 Sep; 122(6):1361-71. PMID: 7690763.
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    15. Grunwald GB, Eisenman LM. Analysis of protein variations in adult and postnatal day 11 staggerer and lurcher mutant mice. Brain Res Dev Brain Res. 1993 May 21; 73(1):146-50. PMID: 8513552.
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    16. Lagunowich LA, Schneider JC, Chasen S, Grunwald GB. Immunohistochemical and biochemical analysis of N-cadherin expression during CNS development. J Neurosci Res. 1992 Jun; 32(2):202-8. PMID: 1404493.
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    17. Roark EF, Paradies NE, Lagunowich LA, Grunwald GB. Evidence for endogenous proteases, mRNA level and insulin as multiple mechanisms of N-cadherin down-regulation during retinal development. Development. 1992 Apr; 114(4):973-84. PMID: 1618157.
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    18. Schiffman JS, Grunwald GB. Differential cell adhesion and expression of N-cadherin among retinoblastoma cell lines. Invest Ophthalmol Vis Sci. 1992 Apr; 33(5):1568-74. PMID: 1559754.
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    19. Chu PG, Grunwald GB. Functional inhibition of retinal pigment epithelial cell-substrate adhesion with a monoclonal antibody against the beta 1 subunit of integrin. Invest Ophthalmol Vis Sci. 1991 May; 32(6):1763-9. PMID: 2032798.
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    20. Lagunowich LA, Grunwald GB. Tissue and age-specificity of post-translational modifications of N-cadherin during chick embryo development. Differentiation. 1991 May; 47(1):19-27. PMID: 1916067.
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    21. Chu P, Grunwald GB. Identification of the 2A10 antigen of retinal pigment epithelium as a beta 1 subunit of integrin. Invest Ophthalmol Vis Sci. 1991 May; 32(6):1757-62. PMID: 2032797.
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    22. Grunwald GB. The conceptual and experimental foundations of vertebrate embryonic cell adhesion research. Dev Biol (N Y 1985). 1991; 7:129-58. PMID: 1804211.
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    23. Lagunowich LA, Donoso LA, Grunwald GB. Identification of mammalian and invertebrate analogues of the avian calcium-dependent cell adhesion protein N-cadherin with synthetic-peptide directed antibodies against a conserved cytoplasmic domain. Biochem Biophys Res Commun. 1990 Oct 15; 172(1):313-20. PMID: 2121144.
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    24. Chu PG, Grunwald GB. Identification of an adhesion-associated protein of the retinal pigment epithelium. Invest Ophthalmol Vis Sci. 1990 May; 31(5):847-55. PMID: 2186012.
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    25. Chu P, Grunwald GB. Generation and characterization of monoclonal antibodies specific for the retinal pigment epithelium. Invest Ophthalmol Vis Sci. 1990 May; 31(5):856-62. PMID: 1692311.
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    26. Grunwald GB, Gilbert SF, Brewer K, Cleland L, Kawai M. Immunocytochemical analysis of embryonic compartmentation with a monoclonal antibody against a cytokeratin-related antigen. Histochemistry. 1990; 94(5):545-53. PMID: 1704360.
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    27. Lagunowich LA, Grunwald GB. Expression of calcium-dependent cell adhesion during ocular development: a biochemical, histochemical and functional analysis. Dev Biol. 1989 Sep; 135(1):158-71. PMID: 2475376.
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    28. Chepenik KP, Grunwald GB. Effects of epidermal growth factor and phorbol 12-myristate 13-acetate on protein phosphorylation in mouse embryo palate mesenchyme cells in vitro. J Craniofac Genet Dev Biol. 1988; 8(2):147-53. PMID: 3263383.
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    29. Dubois C, Magnani JL, Grunwald GB, Spitalnik SL, Trisler GD, Nirenberg M, Ginsburg V. Monoclonal antibody 18B8, which detects synapse-associated antigens, binds to ganglioside GT3 (II3 (NeuAc)3LacCer). J Biol Chem. 1986 Mar 15; 261(8):3826-30. PMID: 3949793.
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    30. Grunwald GB, Gierschik P, Nirenberg M, Spiegel A. Detection of alpha-transducin in retinal rods but not cones. Science. 1986 Feb 21; 231(4740):856-9. PMID: 3080807.
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    31. Balsamo J, Pratt RS, Emmerling MR, Grunwald GB, Lilien J. Identification of the chick neural retina cell surface N-acetylgalactosaminyltransferase using monoclonal antibodies. J Cell Biochem. 1986; 32(2):125-41. PMID: 3097030.
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    32. Grunwald GB, Fredman P, Magnani JL, Trisler D, Ginsburg V, Nirenberg M. Monoclonal antibody 18B8 detects gangliosides associated with neuronal differentiation and synapse formation. Proc Natl Acad Sci U S A. 1985 Jun; 82(12):4008-12. PMID: 3858858.
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    33. Grunwald GB, Pratt RS, Lilien J. Enzymic dissection of embryonic cell adhesive mechanisms. III. Immunological identification of a component of the calcium-dependent adhesive system of embryonic chick neural retina cells. J Cell Sci. 1982 Jun; 55:69-83. PMID: 7107729.
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    34. Grunwald GB, Bromberg RE, Crowley NJ, Lilien J. Enzymatic dissection of embryonic cell adhesive mechanisms. II. Developmental regulation of an endogenous adhesive system in the chick neural retina. Dev Biol. 1981 Sep; 86(2):327-38. PMID: 7286405.
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    35. Grunwald GB, Geller RL, Lilien J. Enzymatic dissection of embryonic cell adhesive mechanisms. J Cell Biol. 1980 Jun; 85(3):766-76. PMID: 7391140.
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