DNA-Directed RNA Polymerases
"DNA-Directed RNA Polymerases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze DNA template-directed extension of the 3'-end of an RNA strand one nucleotide at a time. They can initiate a chain de novo. In eukaryotes, three forms of the enzyme have been distinguished on the basis of sensitivity to alpha-amanitin, and the type of RNA synthesized. (From Enzyme Nomenclature, 1992).
Descriptor ID |
D012321
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MeSH Number(s) |
D08.811.913.696.445.735.270
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Concept/Terms |
DNA-Directed RNA Polymerases- DNA-Directed RNA Polymerases
- DNA Directed RNA Polymerases
- Polymerases, DNA-Directed RNA
- RNA Polymerases, DNA-Directed
- RNA Polymerase
- Polymerase, RNA
- Transcriptases
- DNA-Directed RNA Polymerase
- DNA Directed RNA Polymerase
- Polymerase, DNA-Directed RNA
- RNA Polymerase, DNA-Directed
- DNA-Dependent RNA Polymerases
- DNA Dependent RNA Polymerases
- Polymerases, DNA-Dependent RNA
- RNA Polymerases, DNA-Dependent
- RNA Polymerases
- Polymerases, RNA
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Below are MeSH descriptors whose meaning is more general than "DNA-Directed RNA Polymerases".
Below are MeSH descriptors whose meaning is more specific than "DNA-Directed RNA Polymerases".
This graph shows the total number of publications written about "DNA-Directed RNA Polymerases" by people in this website by year, and whether "DNA-Directed RNA Polymerases" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 2 | 0 | 2 |
2004 | 1 | 0 | 1 |
2005 | 1 | 3 | 4 |
2006 | 3 | 0 | 3 |
2007 | 1 | 0 | 1 |
2008 | 0 | 1 | 1 |
2009 | 2 | 1 | 3 |
2010 | 1 | 2 | 3 |
2011 | 1 | 0 | 1 |
2012 | 0 | 1 | 1 |
2013 | 1 | 0 | 1 |
2014 | 1 | 0 | 1 |
2015 | 1 | 0 | 1 |
2017 | 0 | 1 | 1 |
2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "DNA-Directed RNA Polymerases" by people in Profiles.
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Lokareddy RK, Hou CD, Forti F, Iglesias SM, Li F, Pavlenok M, Horner DS, Niederweis M, Briani F, Cingolani G. Integrative structural analysis of Pseudomonas phage DEV reveals a genome ejection motor. Nat Commun. 2024 Oct 01; 15(1):8482.
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Herbine K, Nayak AR, Temiakov D. Structural basis for substrate binding and selection by human mitochondrial RNA polymerase. Nat Commun. 2024 Aug 20; 15(1):7134.
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Hillen HS, Morozov YI, Sarfallah A, Temiakov D, Cramer P. Structural Basis of Mitochondrial Transcription Initiation. Cell. 2017 Nov 16; 171(5):1072-1081.e10.
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Agaronyan K, Morozov YI, Anikin M, Temiakov D. Mitochondrial biology. Replication-transcription switch in human mitochondria. Science. 2015 Jan 30; 347(6221):548-51.
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Morozov YI, Agaronyan K, Cheung AC, Anikin M, Cramer P, Temiakov D. A novel intermediate in transcription initiation by human mitochondrial RNA polymerase. Nucleic Acids Res. 2014 Apr; 42(6):3884-93.
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Schwinghammer K, Cheung AC, Morozov YI, Agaronyan K, Temiakov D, Cramer P. Structure of human mitochondrial RNA polymerase elongation complex. Nat Struct Mol Biol. 2013 Nov; 20(11):1298-303.
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Blomain ES, McMahon SB. Dynamic regulation of mitochondrial transcription as a mechanism of cellular adaptation. Biochim Biophys Acta. 2012 Sep-Oct; 1819(9-10):1075-9.
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Ringel R, Sologub M, Morozov YI, Litonin D, Cramer P, Temiakov D. Structure of human mitochondrial RNA polymerase. Nature. 2011 Sep 25; 478(7368):269-73.
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Litonin D, Sologub M, Shi Y, Savkina M, Anikin M, Falkenberg M, Gustafsson CM, Temiakov D. Human mitochondrial transcription revisited: only TFAM and TFB2M are required for transcription of the mitochondrial genes in vitro. J Biol Chem. 2010 Jun 11; 285(24):18129-33.
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Hou YM. CCA addition to tRNA: implications for tRNA quality control. IUBMB Life. 2010 Apr; 62(4):251-60.