Induction of experimental autoimmune encephalomyelitis in IL-12 receptor-beta 2-deficient mice: IL-12 responsiveness is not required in the pathogenesis of inflammatory demyelination in the central nervous system.
Zhang GX, Gran B, Yu S, Li J, Siglienti I, Chen X, Kamoun M, Rostami A. Induction of experimental autoimmune encephalomyelitis in IL-12 receptor-beta 2-deficient mice: IL-12 responsiveness is not required in the pathogenesis of inflammatory demyelination in the central nervous system. J Immunol. 2003 Feb 15; 170(4):2153-60.
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Animals
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Apoptosis
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B-Lymphocyte Subsets
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CD4-Positive T-Lymphocytes
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Demyelinating Autoimmune Diseases, CNS
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Encephalomyelitis, Autoimmune, Experimental
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Epitopes, B-Lymphocyte
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Epitopes, T-Lymphocyte
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Genetic Predisposition to Disease
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Glycoproteins
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Inflammation
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Interleukin-12
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Interleukin-18
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Interleukin-18 Receptor alpha Subunit
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Interleukin-23
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Interleukin-23 Subunit p19
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Interleukins
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Mice
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Mice, Inbred C57BL
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Mice, Knockout
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Myelin-Oligodendrocyte Glycoprotein
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Peptide Fragments
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Receptors, Interleukin
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Receptors, Interleukin-12
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Receptors, Interleukin-18
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RNA, Messenger
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Severity of Illness Index
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T-Lymphocyte Subsets
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Up-Regulation